Published in Mol Cell Biol on September 01, 2004
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dSmurf selectively degrades decapentaplegic-activated MAD, and its overexpression disrupts imaginal disc development. J Biol Chem (2003) 1.10
Inverse relationship between Skp2 ubiquitin ligase and the cyclin dependent kinase inhibitor p27Kip1 in prostate cancer. J Urol (2003) 0.99
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Smad7-induced beta-catenin degradation alters epidermal appendage development. Dev Cell (2006) 2.41
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Tumor suppressor CYLD regulates acute lung injury in lethal Streptococcus pneumoniae infections. Immunity (2007) 2.07
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Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer. Mol Cancer Ther (2008) 1.90
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Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression. Proc Natl Acad Sci U S A (2007) 1.81
Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder. EMBO J (2004) 1.75
A crucial role of caspase-3 in osteogenic differentiation of bone marrow stromal stem cells. J Clin Invest (2004) 1.71
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The cardiac determination factor, Nkx2-5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer. J Biol Chem (2003) 1.58
Opposed regulation of corepressor CtBP by SUMOylation and PDZ binding. Mol Cell (2003) 1.57
Identification of novel protein-protein interactions using a versatile mammalian tandem affinity purification expression system. Mol Cell Proteomics (2003) 1.49
TGF-beta induces p65 acetylation to enhance bacteria-induced NF-kappaB activation. EMBO J (2007) 1.49
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Ubiquitination of p21Cip1/WAF1 by SCFSkp2: substrate requirement and ubiquitination site selection. Biochemistry (2005) 1.41
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Smad3 differentially regulates the induction of regulatory and inflammatory T cell differentiation. J Biol Chem (2009) 1.38
Small C-terminal domain phosphatases dephosphorylate the regulatory linker regions of Smad2 and Smad3 to enhance transforming growth factor-beta signaling. J Biol Chem (2006) 1.35
Activation of transforming growth factor-beta signaling by SUMO-1 modification of tumor suppressor Smad4/DPC4. J Biol Chem (2003) 1.32
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Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling. J Biol Chem (2007) 1.31
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TGFBR2 mutations alter smooth muscle cell phenotype and predispose to thoracic aortic aneurysms and dissections. Cardiovasc Res (2010) 1.30
Down-regulation of ZIP4 by RNA interference inhibits pancreatic cancer growth and increases the survival of nude mice with pancreatic cancer xenografts. Clin Cancer Res (2009) 1.30
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Protein serine/threonine phosphatase PPM1A dephosphorylates Smad1 in the bone morphogenetic protein signaling pathway. J Biol Chem (2006) 1.22
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Routine HIV screening in two health-care settings--New York City and New Orleans, 2011-2013. MMWR Morb Mortal Wkly Rep (2014) 1.21
Polymer nanofiber-embedded microchips for detection, isolation, and molecular analysis of single circulating melanoma cells. Angew Chem Int Ed Engl (2013) 1.21
The genomic analysis of the impact of steroid receptor coactivators ablation on hepatic metabolism. Mol Endocrinol (2006) 1.21
The Analytic Information Warehouse (AIW): a platform for analytics using electronic health record data. J Biomed Inform (2013) 1.20
Laparoscopic colon resection early in the learning curve: what is the appropriate setting? Ann Surg (2006) 1.19
A concise total synthesis of largazole, solution structure, and some preliminary structure activity relationships. Org Lett (2008) 1.19
BCL6 represses Smad signaling in transforming growth factor-beta resistance. Cancer Res (2008) 1.19
CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt. Nat Commun (2012) 1.18
Decoding the quantitative nature of TGF-beta/Smad signaling. Trends Cell Biol (2008) 1.18
Smad2 positively regulates the generation of Th17 cells. J Biol Chem (2010) 1.17
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Phase I trial of "bi-shRNAi(furin)/GMCSF DNA/autologous tumor cell" vaccine (FANG) in advanced cancer. Mol Ther (2011) 1.15
TGFbeta1 regulation of vimentin gene expression during differentiation of the C2C12 skeletal myogenic cell line requires Smads, AP-1 and Sp1 family members. Biochim Biophys Acta (2006) 1.15
Smad6 recruits transcription corepressor CtBP to repress bone morphogenetic protein-induced transcription. Mol Cell Biol (2003) 1.13
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dSmurf selectively degrades decapentaplegic-activated MAD, and its overexpression disrupts imaginal disc development. J Biol Chem (2003) 1.10
Use of RNA interference to target cyclin E-overexpressing hepatocellular carcinoma. Cancer Res (2003) 1.10
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