Published in PLoS One on August 18, 2009
The miR-15/107 group of microRNA genes: evolutionary biology, cellular functions, and roles in human diseases. J Mol Biol (2010) 2.20
Exosomal cell-to-cell transmission of alpha synuclein oligomers. Mol Neurodegener (2012) 2.11
Expression of versican 3'-untranslated region modulates endogenous microRNA functions. PLoS One (2010) 1.94
The tumor suppressors p53, p63, and p73 are regulators of microRNA processing complex. PLoS One (2010) 1.63
MicroRNA profiles in allograft tissues and paired urines associate with chronic allograft dysfunction with IF/TA. Am J Transplant (2011) 1.27
Lung Cancer: Are we up to the Challenge? Curr Genomics (2010) 1.21
miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner. Mol Cancer (2011) 1.19
p53 activates the PANK1/miRNA-107 gene leading to downregulation of CDK6 and p130 cell cycle proteins. Nucleic Acids Res (2010) 1.19
Autoregulatory suppression of c-Myc by miR-185-3p. J Biol Chem (2011) 1.16
MicroRNA-107, an oncogene microRNA that regulates tumour invasion and metastasis by targeting DICER1 in gastric cancer. J Cell Mol Med (2011) 1.15
One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor. J Biomed Biotechnol (2011) 1.14
Association of germline microRNA SNPs in pre-miRNA flanking region and breast cancer risk and survival: the Carolina Breast Cancer Study. Cancer Causes Control (2013) 1.13
Regulation of cancer aggressive features in melanoma cells by microRNAs. PLoS One (2011) 1.07
MicroRNAs as lung cancer biomarkers. World J Clin Oncol (2014) 1.07
MiR-185 targets the DNA methyltransferases 1 and regulates global DNA methylation in human glioma. Mol Cancer (2011) 1.05
miR-200c regulates FGFR-dependent epithelial proliferation via Vldlr during submandibular gland branching morphogenesis. Development (2011) 1.04
Systematic screen identifies miRNAs that target RAD51 and RAD51D to enhance chemosensitivity. Mol Cancer Res (2013) 1.01
Toll-like receptor-4 (TLR4) down-regulates microRNA-107, increasing macrophage adhesion via cyclin-dependent kinase 6. J Biol Chem (2011) 1.01
Discordant expression of miR-103/7 and pantothenate kinase host genes in mouse. Mol Genet Metab (2010) 0.97
STIM1, a direct target of microRNA-185, promotes tumor metastasis and is associated with poor prognosis in colorectal cancer. Oncogene (2014) 0.97
Transgenic expression of microRNA-185 causes a developmental arrest of T cells by targeting multiple genes including Mzb1. J Biol Chem (2013) 0.93
Small players with big roles: microRNAs as targets to inhibit breast cancer progression. Curr Drug Targets (2010) 0.93
MicroRNA-185 regulates chemotherapeutic sensitivity in gastric cancer by targeting apoptosis repressor with caspase recruitment domain. Cell Death Dis (2014) 0.92
Repression of ATR pathway by miR-185 enhances radiation-induced apoptosis and proliferation inhibition. Cell Death Dis (2013) 0.91
MicroRNAs - Important Molecules in Lung Cancer Research. Front Genet (2012) 0.90
Clinicopathological and prognostic significance of microRNA-107 in human non small cell lung cancer. Int J Clin Exp Pathol (2014) 0.89
MicroRNA-107 inhibits tumor growth and metastasis by targeting the BDNF-mediated PI3K/AKT pathway in human non-small lung cancer. Int J Oncol (2016) 0.88
MicroRNA-185 targets SOCS3 to inhibit beta-cell dysfunction in diabetes. PLoS One (2015) 0.87
miR-107 regulates cisplatin chemosensitivity of A549 non small cell lung cancer cell line by targeting cyclin dependent kinase 8. Int J Clin Exp Pathol (2014) 0.85
A Cancer-Indicative microRNA Pattern in Normal Prostate Tissue. Int J Mol Sci (2013) 0.85
The novel miR-9500 regulates the proliferation and migration of human lung cancer cells by targeting Akt1. Cell Death Differ (2014) 0.84
Diagnostic Value of Circulating Extracellular miR-134, miR-185, and miR-22 Levels in Lung Adenocarcinoma-Associated Malignant Pleural Effusion. Cancer Res Treat (2014) 0.84
Epigenetic Therapy in Lung Cancer - Role of microRNAs. Front Oncol (2013) 0.84
miR-185 mediates lung epithelial cell death after oxidative stress. Am J Physiol Lung Cell Mol Physiol (2016) 0.82
miR-185 acts as a tumor suppressor by targeting AKT1 in non-small cell lung cancer cells. Int J Clin Exp Pathol (2015) 0.81
TRIM29 functions as an oncogene in gastric cancer and is regulated by miR-185. Int J Clin Exp Pathol (2015) 0.81
MicroRNAs in Acute Myeloid Leukemia and Other Blood Disorders. Leuk Res Treatment (2012) 0.78
miR-107 regulates tumor progression by targeting NF1 in gastric cancer. Sci Rep (2016) 0.78
Overexpression of Lin28 Decreases the Chemosensitivity of Gastric Cancer Cells to Oxaliplatin, Paclitaxel, Doxorubicin, and Fluorouracil in Part via microRNA-107. PLoS One (2015) 0.77
c-Myc-activated long non-coding RNA H19 downregulates miR-107 and promotes cell cycle progression of non-small cell lung cancer. Int J Clin Exp Pathol (2015) 0.77
MicroRNAs As Biomarkers For Clinical Features Of Lung Cancer. Metabolomics (Los Angel) (2012) 0.77
Regulation of TPD52 by antitumor microRNA-218 suppresses cancer cell migration and invasion in lung squamous cell carcinoma. Int J Oncol (2016) 0.76
Annotating non-coding transcription using functional genomics strategies. Brief Funct Genomic Proteomic (2009) 0.76
A step-by-step microRNA guide to cancer development and metastasis. Cell Oncol (Dordr) (2017) 0.75
MicroRNA-1258: An invasion and metastasis regulator that targets heparanase in gastric cancer. Oncol Lett (2017) 0.75
Serum MicroRNA profile in patients with colon adenomas or cancer. BMC Med Genomics (2017) 0.75
MiR-185/AKT and miR-29a/Collagen 1a pathways are activated in IPF BAL cells. Oncotarget (2016) 0.75
A systems biology approach reveals the dose- and time-dependent effect of primary human airway epithelium tissue culture after exposure to cigarette smoke in vitro. Bioinform Biol Insights (2015) 0.75
Downregulation of CCR5 inhibits the proliferation and invasion of cervical cancer cells and is regulated by microRNA-107. Exp Ther Med (2015) 0.75
Chicken gga-miR-103-3p Targets CCNE1 and TFDP2 and Inhibits MDCC-MSB1 Cell Migration. G3 (Bethesda) (2016) 0.75
Role of microRNA-4458 in patients with non-small-cell lung cancer. Oncol Lett (2016) 0.75
miR-185 enhances the inhibition of proliferation and migration induced by ionizing radiation in melanoma. Oncol Lett (2017) 0.75
Cis-acting elements in its 3' UTR mediate post-transcriptional regulation of KRAS. Oncotarget (2016) 0.75
In vitro effect of microRNA-107 targeting Dkk-1 by regulation of Wnt/β-catenin signaling pathway in osteosarcoma. Medicine (Baltimore) (2017) 0.75
MicroRNA-107-5p suppresses non-small cell lung cancer by directly targeting oncogene epidermal growth factor receptor. Oncotarget (2017) 0.75
MiRNA-107 enhances chemosensitivity to paclitaxel by targeting antiapoptotic factor Bcl-w in non small cell lung cancer. Am J Cancer Res (2017) 0.75
Prediction of mammalian microRNA targets. Cell (2003) 53.70
Combinatorial microRNA target predictions. Nat Genet (2005) 50.48
A microRNA polycistron as a potential human oncogene. Nature (2005) 40.21
c-Myc-regulated microRNAs modulate E2F1 expression. Nature (2005) 31.81
GOstat: find statistically overrepresented Gene Ontologies within a group of genes. Bioinformatics (2004) 30.14
A microRNA component of the p53 tumour suppressor network. Nature (2007) 19.25
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature (2000) 19.15
Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res (2004) 18.86
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol Cell (2007) 14.58
Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat Rev Genet (2004) 12.97
Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res (2005) 9.80
Transcriptional activation of miR-34a contributes to p53-mediated apoptosis. Mol Cell (2007) 9.51
The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res (2007) 9.32
Transcription and processing of human microRNA precursors. Mol Cell (2004) 8.98
Getting to the root of miRNA-mediated gene silencing. Cell (2008) 7.17
Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis. Cancer Res (2005) 6.93
p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr Biol (2007) 6.87
Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression. Mol Cell Biol (2007) 6.43
Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues. Mol Cancer (2006) 6.39
CIBEX: center for information biology gene expression database. C R Biol (2004) 6.16
Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells. Proc Natl Acad Sci U S A (2007) 5.50
MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior. J Clin Oncol (2006) 5.40
microRNAs join the p53 network--another piece in the tumour-suppression puzzle. Nat Rev Cancer (2007) 5.38
MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res (2007) 4.95
Micro-RNA profiling in kidney and bladder cancers. Urol Oncol (2007) 4.35
Distinctive microRNA profiles relating to patient survival in esophageal squamous cell carcinoma. Cancer Res (2008) 2.75
MicroRNAs and cell cycle regulation. Cell Cycle (2007) 2.62
Energizing miRNA research: a review of the role of miRNAs in lipid metabolism, with a prediction that miR-103/107 regulates human metabolic pathways. Mol Genet Metab (2007) 2.52
MicroRNA expression profiling during human cord blood-derived CD34 cell erythropoiesis. Exp Hematol (2007) 2.40
Epigenetic silencing of MicroRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer. Pancreatology (2009) 1.76
miRNA in the regulation of skeletal muscle adaptation to acute endurance exercise in C57Bl/6J male mice. PLoS One (2009) 1.67
A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A. J Cell Biol (2009) 1.67
Circular reasoning: microRNAs and cell-cycle control. Trends Biochem Sci (2008) 1.41
GASDERMIN, suppressed frequently in gastric cancer, is a target of LMO1 in TGF-beta-dependent apoptotic signalling. Oncogene (2007) 1.21
Use of RNA interference to target cyclin E-overexpressing hepatocellular carcinoma. Cancer Res (2003) 1.10
Gasdermin (Gsdm) localizing to mouse Chromosome 11 is predominantly expressed in upper gastrointestinal tract but significantly suppressed in human gastric cancer cells. Mamm Genome (2000) 1.07
The RNA continent. Adv Cancer Res (2008) 1.00
Stem cell transcriptome profiling via massive-scale mRNA sequencing. Nat Methods (2008) 31.04
Genome-wide analysis of mammalian promoter architecture and evolution. Nat Genet (2006) 17.19
A promoter-level mammalian expression atlas. Nature (2014) 6.25
An atlas of combinatorial transcriptional regulation in mouse and man. Cell (2010) 6.24
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nat Genet (2009) 6.02
The regulated retrotransposon transcriptome of mammalian cells. Nat Genet (2009) 5.79
Tiny RNAs associated with transcription start sites in animals. Nat Genet (2009) 4.19
TagDust--a program to eliminate artifacts from next generation sequencing data. Bioinformatics (2009) 3.64
The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling. Mol Cell Biol (2003) 3.53
LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death. Mol Cell (2002) 3.36
Hidden layers of human small RNAs. BMC Genomics (2008) 3.31
A rescue strategy for multimapping short sequence tags refines surveys of transcriptional activity by CAGE. Genomics (2008) 3.19
Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat. Nature (2012) 3.08
A comprehensive survey of 3' animal miRNA modification events and a possible role for 3' adenylation in modulating miRNA targeting effectiveness. Genome Res (2010) 2.87
Methods for analyzing deep sequencing expression data: constructing the human and mouse promoterome with deepCAGE data. Genome Biol (2009) 2.86
Transcript annotation in FANTOM3: mouse gene catalog based on physical cDNAs. PLoS Genet (2006) 2.48
Linking promoters to functional transcripts in small samples with nanoCAGE and CAGEscan. Nat Methods (2010) 2.30
The miR-17-5p microRNA is a key regulator of the G1/S phase cell cycle transition. Genome Biol (2008) 2.29
SAMStat: monitoring biases in next generation sequencing data. Bioinformatics (2010) 1.95
Expression profiling in ovarian clear cell carcinoma: identification of hepatocyte nuclear factor-1 beta as a molecular marker and a possible molecular target for therapy of ovarian clear cell carcinoma. Am J Pathol (2003) 1.94
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells. Science (2015) 1.91
Unamplified cap analysis of gene expression on a single-molecule sequencer. Genome Res (2011) 1.79
Cross-mapping and the identification of editing sites in mature microRNAs in high-throughput sequencing libraries. Genome Res (2010) 1.73
Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages. Proc Natl Acad Sci U S A (2012) 1.72
Species-specific loop-mediated isothermal amplification (LAMP) for diagnosis of trypanosomosis. Acta Trop (2007) 1.61
The FANTOM web resource: from mammalian transcriptional landscape to its dynamic regulation. Genome Biol (2009) 1.60
Gateways to the FANTOM5 promoter level mammalian expression atlas. Genome Biol (2015) 1.58
Multifaceted mammalian transcriptome. Curr Opin Cell Biol (2008) 1.52
Molecular networks of DYX1C1 gene show connection to neuronal migration genes and cytoskeletal proteins. Biol Psychiatry (2012) 1.50
Development of a multiplex loop-mediated isothermal amplification (mLAMP) method for the simultaneous detection of bovine Babesia parasites. J Microbiol Methods (2007) 1.48
Adipose tissue microRNAs as regulators of CCL2 production in human obesity. Diabetes (2012) 1.44
Overexpression of cortactin is involved in motility and metastasis of hepatocellular carcinoma. J Hepatol (2004) 1.37
Transcriptional features of genomic regulatory blocks. Genome Biol (2009) 1.37
Analysis of the DNA methylome and transcriptome in granulopoiesis reveals timed changes and dynamic enhancer methylation. Blood (2014) 1.36
FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions. Genome Biol (2009) 1.32
Probabilistic resolution of multi-mapping reads in massively parallel sequencing data using MuMRescueLite. Bioinformatics (2009) 1.32
Effects of cytosine methylation on transcription factor binding sites. BMC Genomics (2014) 1.31
Integrative gene-metabolite network with implemented causality deciphers informational fluxes of sulphur stress response. J Exp Bot (2005) 1.31
Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes. Proc Natl Acad Sci U S A (2012) 1.26
NGSView: an extensible open source editor for next-generation sequencing data. Bioinformatics (2009) 1.20
Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation. Proc Natl Acad Sci U S A (2014) 1.12
Transcription and enhancer profiling in human monocyte subsets. Blood (2014) 1.12
Redefinition of the human mast cell transcriptome by deep-CAGE sequencing. Blood (2014) 1.09
Comparison of CAGE and RNA-seq transcriptome profiling using clonally amplified and single-molecule next-generation sequencing. Genome Res (2014) 1.08
Update of the FANTOM web resource: from mammalian transcriptional landscape to its dynamic regulation. Nucleic Acids Res (2010) 1.08
The enhancer and promoter landscape of human regulatory and conventional T-cell subpopulations. Blood (2014) 1.08
The Tohoku Medical Megabank Project: Design and Mission. J Epidemiol (2016) 1.08
Critical involvement of the phosphatidylinositol 3-kinase/Akt pathway in anchorage-independent growth and hematogeneous intrahepatic metastasis of liver cancer. Cancer Res (2002) 1.07
Dual roles of plasmalemmal chloride channels in induction of cell death. Pflugers Arch (2004) 1.07
Promoter architecture of mouse olfactory receptor genes. Genome Res (2011) 1.06
Subcellular localization of mammalian type II membrane proteins. Traffic (2006) 1.06
The combination of gene perturbation assay and ChIP-chip reveals functional direct target genes for IRF8 in THP-1 cells. Mol Immunol (2010) 1.05
Optimization of turn-back primers in isothermal amplification. Nucleic Acids Res (2011) 1.04
pre-miRNA profiles obtained through application of locked nucleic acids and deep sequencing reveals complex 5'/3' arm variation including concomitant cleavage and polyuridylation patterns. Nucleic Acids Res (2011) 1.02
The short non-coding transcriptome of the protozoan parasite Trypanosoma cruzi. PLoS Negl Trop Dis (2011) 1.01
Do pointing gestures by infants provoke comments from adults? Infant Behav Dev (2007) 1.00
Core promoter structure and genomic context reflect histone 3 lysine 9 acetylation patterns. BMC Genomics (2010) 0.96
Dysadherin expression facilitates cell motility and metastatic potential of human pancreatic cancer cells. Cancer Res (2004) 0.95
LRRN4 and UPK3B are markers of primary mesothelial cells. PLoS One (2011) 0.93
HLA-VBSeq: accurate HLA typing at full resolution from whole-genome sequencing data. BMC Genomics (2015) 0.91
Automated workflow for preparation of cDNA for cap analysis of gene expression on a single molecule sequencer. PLoS One (2012) 0.91
Building promoter aware transcriptional regulatory networks using siRNA perturbation and deepCAGE. Nucleic Acids Res (2010) 0.91
Regional differences in gene expression and promoter usage in aged human brains. Neurobiol Aging (2013) 0.90
Inference of gene regulation via miRNAs during ES cell differentiation using MiRaGE method. Int J Mol Sci (2011) 0.89
High-throughput transcription profiling identifies putative epigenetic regulators of hematopoiesis. Blood (2014) 0.89
Clostridium botulinum type A progenitor toxin binds to Intestine-407 cells via N-acetyllactosamine moiety. Biochem Biophys Res Commun (2005) 0.88
Acquisition and transmission of Theileria parva by vector tick, Rhipicephalus appendiculatus. Acta Trop (2006) 0.88
Two serine protease inhibitors (serpins) that induce a bovine protective immune response against Rhipicephalus appendiculatus ticks. Vaccine (2005) 0.88
Glycyrrhiza uralensis transcriptome landscape and study of phytochemicals. Plant Cell Physiol (2013) 0.88
CC chemokine ligand 2 and leukemia inhibitory factor cooperatively promote pluripotency in mouse induced pluripotent cells. Stem Cells (2011) 0.87
Prerequisite role of persistent cell shrinkage in apoptosis of human epithelial cells. Sheng Li Xue Bao (2007) 0.86
Early-phase occurrence of K+ and Cl- efflux in addition to Ca 2+ mobilization is a prerequisite to apoptosis in HeLa cells. Apoptosis (2012) 0.86
RECLU: a pipeline to discover reproducible transcriptional start sites and their alternative regulation using capped analysis of gene expression (CAGE). BMC Genomics (2014) 0.85
Telomerase activity and telomere length of peripheral blood mononuclear cells in SLE patients. Lupus (2003) 0.84
SDRF2GRAPH: a visualization tool of a spreadsheet-based description of experimental processes. BMC Bioinformatics (2009) 0.84
Autoimmunity to citrullinated type II collagen in rheumatoid arthritis. Mod Rheumatol (2006) 0.84
Spontaneous regression of a cervical intraspinal cyst in a dog. J Vet Med Sci (2009) 0.83
Prediction of function divergence in protein families using the substitution rate variation parameter alpha. Mol Biol Evol (2006) 0.83
Kinetics of circulating endothelial progenitor cells in mice with type II collagen arthritis. Blood Cells Mol Dis (2005) 0.82
Isolation of Rhodococcus equi from the feces of indigenous animals and soil from the Lower Zambezi National Park and Lochinvar National Park, Zambia. J Vet Med Sci (2004) 0.82
Clinicopathological significance of nuclear factor-κB activation in hepatocellular carcinoma. Hepatol Res (2011) 0.81