Published in Nature on July 17, 2003
Kinesin moves by an asymmetric hand-over-hand mechanism. Science (2003) 3.83
Structural basis of HIV-1 tethering to membranes by the BST-2/tetherin ectodomain. Cell Host Microbe (2010) 2.44
Essential role of coiled coils for aggregation and activity of Q/N-rich prions and PolyQ proteins. Cell (2010) 1.76
Structure of the mid-region of tropomyosin: bending and binding sites for actin. Proc Natl Acad Sci U S A (2005) 1.72
Coiled-coil irregularities and instabilities in group A Streptococcus M1 are required for virulence. Science (2008) 1.70
Three-dimensional reconstruction of tarantula myosin filaments suggests how phosphorylation may regulate myosin activity. J Mol Biol (2008) 1.59
Crystal structures of human cardiac beta-myosin II S2-Delta provide insight into the functional role of the S2 subfragment. Proc Natl Acad Sci U S A (2006) 1.26
Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains. Proc Natl Acad Sci U S A (2007) 1.24
Bioinformatics assessment of beta-myosin mutations reveals myosin's high sensitivity to mutations. Trends Cardiovasc Med (2008) 1.20
The elastic properties of the structurally characterized myosin II S2 subdomain: a molecular dynamics and normal mode analysis. Biophys J (2008) 1.17
Removal of the cardiac myosin regulatory light chain increases isometric force production. FASEB J (2009) 1.14
Structural and biophysical analysis of BST-2/tetherin ectodomains reveals an evolutionary conserved design to inhibit virus release. J Biol Chem (2010) 1.13
Coiled-coil nanomechanics and uncoiling and unfolding of the superhelix and alpha-helices of myosin. Biophys J (2006) 1.12
A small surface hydrophobic stripe in the coiled-coil domain of type I keratins mediates tetramer stability. J Cell Biol (2005) 1.09
Common structural motifs for the regulation of divergent class II myosins. J Biol Chem (2010) 1.08
Invertebrate muscles: thin and thick filament structure; molecular basis of contraction and its regulation, catch and asynchronous muscle. Prog Neurobiol (2008) 1.03
Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human proteome. PLoS One (2011) 0.98
Structural basis of the relaxed state of a Ca2+-regulated myosin filament and its evolutionary implications. Proc Natl Acad Sci U S A (2013) 0.96
Antiparallel coiled-coil-mediated dimerization of myosin X. Proc Natl Acad Sci U S A (2012) 0.96
How sequence directs bending in tropomyosin and other two-stranded alpha-helical coiled coils. Protein Sci (2010) 0.88
Structural insights into the molecular mechanisms of cauliflower mosaic virus transmission by its insect vector. J Virol (2010) 0.86
Structure-function analysis of the C-terminal domain of CNM67, a core component of the Saccharomyces cerevisiae spindle pole body. J Biol Chem (2011) 0.83
Structural and functional insights on the Myosin superfamily. Bioinform Biol Insights (2012) 0.83
Subunit b-dimer of the Escherichia coli ATP synthase can form left-handed coiled-coils. Biophys J (2008) 0.82
A conformational transition in the myosin VI converter contributes to the variable step size. Biophys J (2011) 0.81
An unstable head-rod junction may promote folding into the compact off-state conformation of regulated myosins. J Mol Biol (2007) 0.78
Distribution and evolution of stable single α-helices (SAH domains) in myosin motor proteins. PLoS One (2017) 0.75
Structure of myosin filaments from relaxed Lethocerus flight muscle by cryo-EM at 6 Å resolution. Sci Adv (2016) 0.75
Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor. Structure (2007) 2.25
Structure of the mid-region of tropomyosin: bending and binding sites for actin. Proc Natl Acad Sci U S A (2005) 1.72
Regulation of muscle contraction by tropomyosin and troponin: how structure illuminates function. Adv Protein Chem (2005) 1.66
Crystal structure of apo-calmodulin bound to the first two IQ motifs of myosin V reveals essential recognition features. Proc Natl Acad Sci U S A (2006) 1.63
Crystal structure of scallop Myosin s1 in the pre-power stroke state to 2.6 a resolution: flexibility and function in the head. Structure (2003) 1.46
Myosin V from Drosophila reveals diversity of motor mechanisms within the myosin V family. J Biol Chem (2005) 1.32
The crystal structure of the C-terminal fragment of striated-muscle alpha-tropomyosin reveals a key troponin T recognition site. Proc Natl Acad Sci U S A (2002) 1.31
DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond. FEBS J (2011) 1.18
Alternatively spliced exon B of myosin Va is essential for binding the tail-associated light chain shared by dynein. Biochemistry (2006) 1.17
Charged single alpha-helix: a versatile protein structural motif. Proteins (2009) 1.12
Myosin subfragment 1 structures reveal a partially bound nucleotide and a complex salt bridge that helps couple nucleotide and actin binding. Proc Natl Acad Sci U S A (2004) 1.07
The on-off switch in regulated myosins: different triggers but related mechanisms. J Mol Biol (2009) 1.03
Selective perturbation of the myosin recovery stroke by point mutations at the base of the lever arm affects ATP hydrolysis and phosphate release. J Biol Chem (2007) 1.01
Two-headed binding of the unphosphorylated nonmuscle heavy meromyosin.ADP complex to actin. Biochemistry (2004) 0.98
Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human proteome. PLoS One (2011) 0.98
Visualizing key hinges and a potential major source of compliance in the lever arm of myosin. Proc Natl Acad Sci U S A (2010) 0.96
Increased prevalence of transfusion-transmitted virus and cross-reactivity with immunodominant epitopes of the HRES-1/p28 endogenous retroviral autoantigen in patients with systemic lupus erythematosus. Clin Immunol (2005) 0.93
Crystal structure of the S100A4-nonmuscle myosin IIA tail fragment complex reveals an asymmetric target binding mechanism. Proc Natl Acad Sci U S A (2012) 0.93
LC8 dynein light chain (DYNLL1) binds to the C-terminal domain of ATM-interacting protein (ATMIN/ASCIZ) and regulates its subcellular localization. Biochem Biophys Res Commun (2011) 0.93
Structural evidence for non-canonical binding of Ca2+ to a canonical EF-hand of a conventional myosin. J Biol Chem (2005) 0.92
Affinity, avidity, and kinetics of target sequence binding to LC8 dynein light chain isoforms. J Biol Chem (2010) 0.90
Charged single alpha-helices in proteomes revealed by a consensus prediction approach. Biochim Biophys Acta (2012) 0.89
Bioinformatics education in high school: implications for promoting science, technology, engineering, and mathematics careers. CBE Life Sci Educ (2013) 0.88
Structural insights into the Trp-cage folding intermediate formation. Chemistry (2013) 0.88
Laparoscopic repair of circumcaval ureter: one-year follow-up of three patients and literature review. Urology (2009) 0.87
The structure of the complex of calmodulin with KAR-2: a novel mode of binding explains the unique pharmacology of the drug. J Biol Chem (2004) 0.86
Folded-unfolded cross-predictions and protein evolution: the case study of coiled-coils. FEBS Lett (2010) 0.85
Striatins contain a noncanonical coiled coil that binds protein phosphatase 2A A subunit to form a 2:2 heterotetrameric core of striatin-interacting phosphatase and kinase (STRIPAK) complex. J Biol Chem (2014) 0.81
Purification, crystallization and preliminary X-ray crystallographic analysis of squid heavy meromyosin. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.81
Easy method for keratin 14 gene amplification to exclude pseudogene sequences: new keratin 5 and 14 mutations in epidermolysis bullosa simplex. J Invest Dermatol (2008) 0.80
Coiled coils as possible models of protein structure evolution. Biomol Concepts (2011) 0.79
DYNLL2 dynein light chain binds to an extended linear motif of myosin 5a tail that has structural plasticity. Biochemistry (2014) 0.78
Crystal structure of a phosphorylated light chain domain of scallop smooth-muscle myosin. Biophys J (2011) 0.78
An unstable head-rod junction may promote folding into the compact off-state conformation of regulated myosins. J Mol Biol (2007) 0.78
Detection of TT virus in patients with idiopathic inflammatory myopathies. Ann N Y Acad Sci (2005) 0.77
Association between carcinosarcoma and the transplanted kidney. Anticancer Res (2006) 0.75
Pillars article: three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature. 1993. 364: 33-39. J Immunol (2015) 0.75
Engineering lysine reactivity as a conformational sensor in the Dictyostelium myosin II motor domain. J Muscle Res Cell Motil (2004) 0.75
[From the surgical field to the microscope. A new tool to identify the lymph node specimens in oncologic surgery]. Magy Seb (2011) 0.75
Epidermolysis bullosa simplex with mottled pigmentation - mutation analysis proved the diagnosis in a four-generation pedigree. Eur J Dermatol (2010) 0.75
High-tone electric muscles stimulation of thigh augments the impaired penile blood flow of diabetic patients without improving symptoms of erectile dysfunction. Clin Nephrol (2013) 0.75