Published in J Biol Chem on April 21, 2007
The globular tail domain puts on the brake to stop the ATPase cycle of myosin Va. Proc Natl Acad Sci U S A (2008) 1.31
Atomically detailed simulation of the recovery stroke in myosin by Milestoning. Proc Natl Acad Sci U S A (2010) 1.31
Evidence for an interaction between the SH3 domain and the N-terminal extension of the essential light chain in class II myosins. J Mol Biol (2007) 1.03
Direct real-time detection of the actin-activated power stroke within the myosin catalytic domain. Proc Natl Acad Sci U S A (2013) 0.99
Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke. Proc Natl Acad Sci U S A (2010) 0.91
The influence of myosin converter and relay domains on cross-bridge kinetics of Drosophila indirect flight muscle. Biophys J (2010) 0.91
Structural mechanism of the ATP-induced dissociation of rigor myosin from actin. Proc Natl Acad Sci U S A (2011) 0.86
Mutating the converter-relay interface of Drosophila myosin perturbs ATPase activity, actin motility, myofibril stability and flight ability. J Mol Biol (2010) 0.85
The superfast human extraocular myosin is kinetically distinct from the fast skeletal IIa, IIb, and IId isoforms. J Biol Chem (2013) 0.82
Energetics of subdomain movements and fluorescence probe solvation environment change in ATP-bound myosin. Eur Biophys J (2008) 0.80
Poorly understood aspects of striated muscle contraction. Biomed Res Int (2015) 0.78
A subdomain interaction at the base of the lever allosterically tunes the mechanochemical mechanism of myosin 5a. PLoS One (2013) 0.75
The Relay/Converter Interface Influences Hydrolysis of ATP by Skeletal Muscle Myosin II. J Biol Chem (2015) 0.75
PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data. Nucleic Acids Res (2003) 6.19
Mechanism of blebbistatin inhibition of myosin II. J Biol Chem (2004) 5.45
The Plasmodium genome database. Nature (2002) 4.36
Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor. Structure (2007) 2.25
Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plus-end-directed motor. EMBO J (2002) 2.22
The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression. EMBO Rep (2008) 2.22
Adenosine diphosphate and strain sensitivity in myosin motors. Philos Trans R Soc Lond B Biol Sci (2004) 2.11
Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights. Acta Crystallogr D Biol Crystallogr (2013) 2.03
Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C. J Biol Chem (2005) 1.86
Myosin cleft movement and its coupling to actomyosin dissociation. Nat Struct Biol (2003) 1.80
The core FH2 domain of diaphanous-related formins is an elongated actin binding protein that inhibits polymerization. Mol Cell (2004) 1.74
Upregulation of cardiomyocyte ribonucleotide reductase increases intracellular 2 deoxy-ATP, contractility, and relaxation. J Mol Cell Cardiol (2011) 1.72
Keeping uracil out of DNA: physiological role, structure and catalytic mechanism of dUTPases. Acc Chem Res (2009) 1.62
Visualization of an unstable coiled coil from the scallop myosin rod. Nature (2003) 1.45
What kinesin does at roadblocks: the coordination mechanism for molecular walking. EMBO J (2003) 1.41
Cryptococcus neoformans senses CO2 through the carbonic anhydrase Can2 and the adenylyl cyclase Cac1. Eukaryot Cell (2006) 1.41
Acetylation regulates tropomyosin function in the fission yeast Schizosaccharomyces pombe. J Cell Sci (2007) 1.39
Interferon-alpha therapy in children with malignant diseases: clinical experience in twenty-four patients treated in a single pediatric oncology unit. Med Pediatr Oncol (2002) 1.39
Phosphatidylinositol phosphate kinase type 1gamma and beta1-integrin cytoplasmic domain bind to the same region in the talin FERM domain. J Biol Chem (2003) 1.37
The mechanism of the reverse recovery step, phosphate release, and actin activation of Dictyostelium myosin II. J Biol Chem (2008) 1.37
Myo1c is designed for the adaptation response in the inner ear. EMBO J (2004) 1.36
What limits the velocity of fast-skeletal muscle contraction in mammals? J Mol Biol (2005) 1.35
Myosin V from Drosophila reveals diversity of motor mechanisms within the myosin V family. J Biol Chem (2005) 1.32
Protonation, photobleaching, and photoactivation of yellow fluorescent protein (YFP 10C): a unifying mechanism. Biochemistry (2005) 1.30
Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis. Proc Natl Acad Sci U S A (2012) 1.29
Targeted amino-terminal acetylation of recombinant proteins in E. coli. PLoS One (2010) 1.23
DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond. FEBS J (2011) 1.18
Alternatively spliced exon B of myosin Va is essential for binding the tail-associated light chain shared by dynein. Biochemistry (2006) 1.17
Reversible movement of switch 1 loop of myosin determines actin interaction. EMBO J (2007) 1.17
Role of tropomyosin isoforms in the calcium sensitivity of striated muscle thin filaments. J Muscle Res Cell Motil (2007) 1.15
Kinetic mechanism of human dUTPase, an essential nucleotide pyrophosphatase enzyme. J Biol Chem (2007) 1.14
Calcium sensitivity of the cross-bridge cycle of Myo1c, the adaptation motor in the inner ear. Proc Natl Acad Sci U S A (2008) 1.13
Further characterization of the interaction between the cytoskeletal proteins talin and vinculin. Biochem J (2002) 1.13
Charged single alpha-helix: a versatile protein structural motif. Proteins (2009) 1.12
The flexibility of two tropomyosin mutants, D175N and E180G, that cause hypertrophic cardiomyopathy. Biochem Biophys Res Commun (2012) 1.12
Kinetic analysis of Drosophila muscle myosin isoforms suggests a novel mode of mechanochemical coupling. J Biol Chem (2003) 1.12
Human myosin Vc is a low duty ratio, nonprocessive molecular motor. J Biol Chem (2008) 1.11
Ribosomal intersubunit bridge B2a is involved in factor-dependent translation initiation and translational processivity. J Mol Biol (2008) 1.10
Effects of two familial hypertrophic cardiomyopathy mutations in alpha-tropomyosin, Asp175Asn and Glu180Gly, on the thermal unfolding of actin-bound tropomyosin. Biophys J (2004) 1.10
Dynamics of actomyosin interactions in relation to the cross-bridge cycle. Philos Trans R Soc Lond B Biol Sci (2004) 1.08
Processive translocation mechanism of the human Bloom's syndrome helicase along single-stranded DNA. Nucleic Acids Res (2010) 1.08
Shaking the myosin family tree: biochemical kinetics defines four types of myosin motor. Semin Cell Dev Biol (2011) 1.08
A modulatory role for the troponin T tail domain in thin filament regulation. J Biol Chem (2002) 1.07
Emerging complex pathways of the actomyosin powerstroke. Trends Biochem Sci (2010) 1.07
Kinetic mechanism of myosinV-S1 using a new fluorescent ATP analogue. Biochemistry (2006) 1.06
Identification of functional differences between recombinant human α and β cardiac myosin motors. Cell Mol Life Sci (2012) 1.06
Structural basis for the interaction between the cytoplasmic domain of the hyaluronate receptor layilin and the talin F3 subdomain. J Mol Biol (2008) 1.06
Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase. FEBS Lett (2007) 1.05
Stoichiometry of a regulatory splicing complex revealed by single-molecule analyses. EMBO J (2010) 1.05
Dictyostelium myosin-IE is a fast molecular motor involved in phagocytosis. J Cell Sci (2006) 1.03
Analysis of nucleotide binding to Dictyostelium myosin II motor domains containing a single tryptophan near the active site. J Biol Chem (2002) 1.03
The slow skeletal muscle isoform of myosin shows kinetic features common to smooth and non-muscle myosins. J Biol Chem (2006) 1.02
Functional analysis of the GTPases EngA and YhbZ encoded by Salmonella typhimurium. Protein Sci (2007) 1.02
Mechanical unfolding of human telomere G-quadruplex DNA probed by integrated fluorescence and magnetic tweezers spectroscopy. Nucleic Acids Res (2013) 1.01
Mutations in the relay loop region result in dominant-negative inhibition of myosin II function in Dictyostelium. EMBO Rep (2002) 1.01
Switch 1 mutation S217A converts myosin V into a low duty ratio motor. J Biol Chem (2008) 1.01
Erratum to: Identification of functional differences between recombinant human α and β cardiac myosin motors. Cell Mol Life Sci (2012) 1.01
Differential regulation of the actomyosin interaction by skeletal and cardiac troponin isoforms. J Biol Chem (2002) 1.01
Changes in Mg2+ ion concentration and heavy chain phosphorylation regulate the motor activity of a class I myosin. J Biol Chem (2004) 0.99
Dimerized Drosophila myosin VIIa: a processive motor. Proc Natl Acad Sci U S A (2006) 0.99
Two-headed binding of the unphosphorylated nonmuscle heavy meromyosin.ADP complex to actin. Biochemistry (2004) 0.98
Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human proteome. PLoS One (2011) 0.98
An enzyme-trap approach allows isolation of intermediates in cobalamin biosynthesis. Nat Chem Biol (2012) 0.98
Shared developmental roles and transcriptional control of autophagy and apoptosis in Caenorhabditis elegans. J Cell Sci (2011) 0.96
A variable domain near the ATP-binding site in Drosophila muscle myosin is part of the communication pathway between the nucleotide and actin-binding sites. J Mol Biol (2007) 0.96
A kinetic model of the co-operative binding of calcium and ADP to scallop (Argopecten irradians) heavy meromyosin. Biochem J (2002) 0.96
Kinetic mechanism of myosin IXB and the contributions of two class IX-specific regions. J Biol Chem (2005) 0.95
Kinetic and mechanistic basis of the nonprocessive Kinesin-3 motor NcKin3. J Biol Chem (2006) 0.94
The effect of F-actin on the relay helix position of myosin II, as revealed by tryptophan fluorescence, and its implications for mechanochemical coupling. Biochemistry (2004) 0.94
Crystal structure of the Ca(2+)-form and Ca(2+)-binding kinetics of metastasis-associated protein, S100A4. FEBS Lett (2008) 0.93
Stretching the lever-arm theory. Nature (2002) 0.93
Crystal structure of the S100A4-nonmuscle myosin IIA tail fragment complex reveals an asymmetric target binding mechanism. Proc Natl Acad Sci U S A (2012) 0.93
LC8 dynein light chain (DYNLL1) binds to the C-terminal domain of ATM-interacting protein (ATMIN/ASCIZ) and regulates its subcellular localization. Biochem Biophys Res Commun (2011) 0.93
Myosin VIIB from Drosophila is a high duty ratio motor. J Biol Chem (2005) 0.92
The myosin-activated thin filament regulatory state, M⁻-open: a link to hypertrophic cardiomyopathy (HCM). J Muscle Res Cell Motil (2014) 0.92
Loop 1 of transducer region in mammalian class I myosin, Myo1b, modulates actin affinity, ATPase activity, and nucleotide access. J Biol Chem (2005) 0.92
Alternative exon 9-encoded relay domains affect more than one communication pathway in the Drosophila myosin head. J Mol Biol (2009) 0.92
Drug effect prediction by polypharmacology-based interaction profiling. J Chem Inf Model (2011) 0.92
Structural evidence for non-canonical binding of Ca2+ to a canonical EF-hand of a conventional myosin. J Biol Chem (2005) 0.92
Cooperative regulation of myosin-S1 binding to actin filaments by a continuous flexible Tm-Tn chain. Eur Biophys J (2012) 0.92
Loop 2 of limulus myosin III is phosphorylated by protein kinase A and autophosphorylation. Biochemistry (2007) 0.92
Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke. Proc Natl Acad Sci U S A (2010) 0.91
Asymmetric mode of Ca²⁺-S100A4 interaction with nonmuscle myosin IIA generates nanomolar affinity required for filament remodeling. Structure (2012) 0.90
Affinity, avidity, and kinetics of target sequence binding to LC8 dynein light chain isoforms. J Biol Chem (2010) 0.90
Myosin cleft closure determines the energetics of the actomyosin interaction. FASEB J (2010) 0.90
Drug effect unveils inter-head cooperativity and strain-dependent ADP release in fast skeletal actomyosin. J Biol Chem (2009) 0.90