Published in J Am Chem Soc on August 20, 2003
Enzymatic incorporation of a third nucleobase pair. Nucleic Acids Res (2007) 1.79
Synthesis and properties of size-expanded DNAs: toward designed, functional genetic systems. Acc Chem Res (2007) 1.36
Artificially expanded genetic information system: a new base pair with an alternative hydrogen bonding pattern. Nucleic Acids Res (2006) 1.32
Model systems for understanding DNA base pairing. Curr Opin Chem Biol (2007) 1.18
Redesigning the architecture of the base pair: toward biochemical and biological function of new genetic sets. Chem Biol (2009) 1.05
Exploring the limits of DNA size: naphtho-homologated DNA bases and pairs. J Am Chem Soc (2006) 1.04
Toward a designed, functioning genetic system with expanded-size base pairs: solution structure of the eight-base xDNA double helix. J Am Chem Soc (2006) 0.91
Synthetic Routes to a Series of Proximal and Distal 2'-Deoxy Fleximers. Synthesis (Stuttg) (2012) 0.83
Nucleoside alpha-thiotriphosphates, polymerases and the exonuclease III analysis of oligonucleotides containing phosphorothioate linkages. Nucleic Acids Res (2007) 0.81
Investigating the binding mode of an inhibitor of the MBNL1·RNA complex in myotonic dystrophy type 1 (DM1) leads to the unexpected discovery of a DNA-selective binder. Chembiochem (2012) 0.80
DNA polymerases engineered by directed evolution to incorporate non-standard nucleotides. Front Microbiol (2014) 0.80
A computational study of expanded heterocyclic nucleosides in DNA. J Biomol Struct Dyn (2008) 0.79
A new, but old, nucleoside analog: the first synthesis of 1-deaza-2'-deoxyguanosine and its properties as a nucleoside and as oligodeoxynucleotides. Nucleic Acids Res (2003) 0.78
Structural basis for a six nucleotide genetic alphabet. J Am Chem Soc (2015) 0.77
Unnatural imidazopyridopyrimidine:naphthyridine base pairs: selective incorporation and extension reaction by Deep Vent (exo- ) DNA polymerase. Nucleic Acids Res (2009) 0.76
Flex-nucleoside analogues - Novel therapeutics against filoviruses. Bioorg Med Chem Lett (2017) 0.75
The medaka draft genome and insights into vertebrate genome evolution. Nature (2007) 5.77
Role of TBX1 in human del22q11.2 syndrome. Lancet (2003) 4.45
A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming. Nat Genet (2009) 2.96
Diagnosis and classification of myelodysplastic syndrome: International Working Group on Morphology of myelodysplastic syndrome (IWGM-MDS) consensus proposals for the definition and enumeration of myeloblasts and ring sideroblasts. Haematologica (2008) 2.69
DNA sequence and analysis of human chromosome 8. Nature (2006) 1.91
Piccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP-GEFII.Rim2. Piccolo complex in cAMP-dependent exocytosis. J Biol Chem (2002) 1.85
Endoscopic management of biliary complications after adult living donor liver transplantation. Am J Gastroenterol (2006) 1.78
Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region. Biochem Biophys Res Commun (2003) 1.77
Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. Antimicrob Agents Chemother (2010) 1.74
Functional SNPs in the distal promoter of the ST2 gene are associated with atopic dermatitis. Hum Mol Genet (2005) 1.70
Genomic organization of the sex-determining and adjacent regions of the sex chromosomes of medaka. Genome Res (2006) 1.61
LOXL1 genetic polymorphisms are associated with exfoliation glaucoma in the Japanese population. Mol Vis (2008) 1.61
Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins. Exp Cell Res (2007) 1.60
Efficacy and safety of low-pressured and short-time dilation in endoscopic papillary balloon dilation for bile duct stone removal. J Gastroenterol Hepatol (2007) 1.60
Results of the Tokyo trial of prevention of post-ERCP pancreatitis with risperidone-2: a multicenter, randomized, placebo-controlled, double-blind clinical trial. Gastrointest Endosc (2013) 1.58
Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population. Nat Genet (2012) 1.58
Three susceptible loci associated with primary open-angle glaucoma identified by genome-wide association study in a Japanese population. Proc Natl Acad Sci U S A (2009) 1.51
Impact of introduction of wire-guided cannulation in therapeutic biliary endoscopic retrograde cholangiopancreatography. J Gastroenterol Hepatol (2011) 1.47
Silencing of int6 gene restores function of the ischaemic hindlimb in a rat model of peripheral arterial disease. Cardiovasc Res (2011) 1.46
Lower incidence of biliary carcinoma in patients with primary sclerosing cholangitis and high serum levels of immunoglobulin E. Clin Gastroenterol Hepatol (2011) 1.44
FTY720 reduces T-cell recruitment into murine intestinal allograft and prevents activation of graft-infiltrating cells. Transplantation (2003) 1.44
Long-term prognosis of autoimmune pancreatitis with and without corticosteroid treatment. Gut (2007) 1.43
Differences in blast immunophenotypes among disease types in myelodysplastic syndromes: a multicenter validation study. Leuk Res (2012) 1.42
Clinical utility of single-operator cholangiopancreatoscopy using a SpyGlass probe through an endoscopic retrograde cholangiopancreatography catheter. J Gastroenterol Hepatol (2012) 1.42
Circadian rhythms and the effect of glucocorticoids on expression of the clock gene period1 in canine peripheral blood mononuclear cells. Vet J (2012) 1.41
Prevalence of vitreous hemorrhage following coronary revascularization in patients with diabetic retinopathy. Circ J (2010) 1.40
Is macrocytosis a favourable prognostic factor in myelodysplastic syndrome patients without increased blasts? Br J Haematol (2003) 1.39
Rapid and accurate identification of human-associated staphylococci by use of multiplex PCR. J Clin Microbiol (2011) 1.37
Efficacy and safety of luseogliflozin as monotherapy in Japanese patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled, phase 3 study. Curr Med Res Opin (2014) 1.37
Cholecystitis after metallic stent placement in patients with malignant distal biliary obstruction. Clin Gastroenterol Hepatol (2006) 1.31
MicroRNAs miR-199a-5p and -3p target the Brm subunit of SWI/SNF to generate a double-negative feedback loop in a variety of human cancers. Cancer Res (2010) 1.29
Mammalian 5-formyluracil-DNA glycosylase. 2. Role of SMUG1 uracil-DNA glycosylase in repair of 5-formyluracil and other oxidized and deaminated base lesions. Biochemistry (2003) 1.27
MEPD: a resource for medaka gene expression patterns. Bioinformatics (2005) 1.22
Measurement of radial and axial forces of biliary self-expandable metallic stents. Gastrointest Endosc (2009) 1.22
IL-33-mediated innate response and adaptive immune cells contribute to maximum responses of protease allergen-induced allergic airway inflammation. J Immunol (2013) 1.19
Smqnr, a new chromosome-carried quinolone resistance gene in Stenotrophomonas maltophilia. Antimicrob Agents Chemother (2008) 1.18
Development of vaccine strains of H5 and H7 influenza viruses. Jpn J Vet Res (2008) 1.18
Frequent translocations occur between low copy repeats on chromosome 22q11.2 (LCR22s) and telomeric bands of partner chromosomes. Hum Mol Genet (2003) 1.17
Diagnostic utility of flow cytometry in low-grade myelodysplastic syndromes: a prospective validation study. Haematologica (2009) 1.16
Electrotransformation of Lactobacillus delbrueckii subsp. bulgaricus and L. delbrueckii subsp. lactis with various plasmids. Appl Environ Microbiol (2002) 1.16
Dose-finding study of luseogliflozin in Japanese patients with type 2 diabetes mellitus: a 12-week, randomized, double-blind, placebo-controlled, phase II study. Curr Med Res Opin (2014) 1.16
Genetic diversity of staphylocoagulase genes (coa): insight into the evolution of variable chromosomal virulence factors in Staphylococcus aureus. PLoS One (2009) 1.14
Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma. Hum Genet (2005) 1.14
Clinical outcomes of chemotherapy for diabetic and nondiabetic patients with pancreatic cancer: better prognosis with statin use in diabetic patients. Pancreas (2013) 1.12
Efficacy and safety of luseogliflozin monotherapy in Japanese patients with type 2 diabetes mellitus: a 12-week, randomized, placebo-controlled, phase II study. Curr Med Res Opin (2014) 1.12
A novel giant gene CSMD3 encoding a protein with CUB and sushi multiple domains: a candidate gene for benign adult familial myoclonic epilepsy on human chromosome 8q23.3-q24.1. Biochem Biophys Res Commun (2003) 1.12
Management of distal malignant biliary obstruction with the ComVi stent, a new covered metallic stent. Surg Endosc (2009) 1.11
Slow pull versus suction in endoscopic ultrasound-guided fine-needle aspiration of pancreatic solid masses. Dig Dis Sci (2014) 1.09
Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway. Genomics (2007) 1.09
Synthesis and structure of duplex DNA containing the genotoxic nucleobase lesion N7-methylguanine. J Am Chem Soc (2008) 1.09
Tumor-associated calcium signal transducer 2 is required for the proper subcellular localization of claudin 1 and 7: implications in the pathogenesis of gelatinous drop-like corneal dystrophy. Am J Pathol (2010) 1.09
The immunosuppressive agent mizoribine monophosphate forms a transition state analogue complex with inosine monophosphate dehydrogenase. Biochemistry (2003) 1.09
Preliminary report on a new, fully covered, metal stent designed for the treatment of pancreatic fluid collections. Gastrointest Endosc (2013) 1.08
Role of the IL-6 classic- and trans-signaling pathways in corneal sterile inflammation and wound healing. Invest Ophthalmol Vis Sci (2011) 1.08
Dapagliflozin as monotherapy or combination therapy in Japanese patients with type 2 diabetes: an open-label study. Diabetes Ther (2014) 1.08
Mutagenicity of 5-formylcytosine, an oxidation product of 5-methylcytosine, in DNA in mammalian cells. J Biochem (2002) 1.07
Laparoscopic treatment of gallbladder volvulus: a pediatric case report and literature review. J Laparoendosc Adv Surg Tech A (2008) 1.07
Impact of S-1 on the survival of patients with advanced pancreatic cancer. Pancreas (2010) 1.06
Endoscopic papillary balloon dilation for bile duct stone: immediate and long-term outcomes in 1000 patients. Clin Gastroenterol Hepatol (2007) 1.05
The hotei mutation of medaka in the anti-Mullerian hormone receptor causes the dysregulation of germ cell and sexual development. Proc Natl Acad Sci U S A (2007) 1.04
A potent 2'-O-methylated RNA-based microRNA inhibitor with unique secondary structures. Nucleic Acids Res (2012) 1.04
Association between IFNA genotype and the risk of sarcoidosis. Hum Genet (2004) 1.03
Genetic association of glutathione peroxidase-1 with coronary artery calcification in type 2 diabetes: a case control study with multi-slice computed tomography. Cardiovasc Diabetol (2007) 1.03
Strong immunostimulatory activity of AT-oligodeoxynucleotide requires a six-base loop with a self-stabilized 5'-C...G-3' stem structure. Cell Microbiol (2006) 1.03
Comparison of enzymatic characterization and gene organization of cyclic nucleotide phosphodiesterase 8 family in humans. Cell Signal (2003) 1.01
Complete nucleotide sequences of mitochondrial genomes of two solitary entoprocts, Loxocorone allax and Loxosomella aloxiata: implications for lophotrochozoan phylogeny. Mol Phylogenet Evol (2008) 1.01
Efficacy of Solifenacin on Irritable Bowel Syndrome With Diarrhea: Open-label Prospective Pilot Trial. J Neurogastroenterol Motil (2012) 1.01
No enhancement of nuclear entry by direct conjugation of a nuclear localization signal peptide to linearized DNA. Bioconjug Chem (2003) 1.01
Transmural biliary drainage can be an alternative to transpapillary drainage in patients with an indwelling duodenal stent. Dig Dis Sci (2014) 1.01
New NTP analogs: the synthesis of 4'-thioUTP and 4'-thioCTP and their utility for SELEX. Nucleic Acids Res (2005) 1.00
Repair of 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine-induced DNA single-strand breaks by transcription-coupled nucleotide excision repair. Cancer Res (2008) 1.00
New method of covered wallstents for distal malignant biliary obstruction to reduce early stent-related complications based on characteristics. Dig Endosc (2010) 1.00
Synthesis and physical and physiological properties of 4'-thioRNA: application to post-modification of RNA aptamer toward NF-kappaB. Nucleic Acids Res (2004) 1.00
Safety and efficacy of laparoscopic percutaneous extraperitoneal closure for inguinal hernias and hydroceles in children: a comparison with traditional open repair. J Laparoendosc Adv Surg Tech A (2013) 1.00
Subcellular localization of cyclic nucleotide phosphodiesterase type 10A variants, and alteration of the localization by cAMP-dependent protein kinase-dependent phosphorylation. J Biol Chem (2003) 0.99
Clinical significance of bile cytology via an endoscopic nasobiliary drainage tube for pathological diagnosis of malignant biliary strictures. J Hepatobiliary Pancreat Sci (2011) 0.99
Long-term prognosis of autoimmune pancreatitis in terms of glucose tolerance. Pancreas (2012) 0.99
Total synthesis of caprazol, a core structure of the caprazamycin antituberculosis antibiotics. Angew Chem Int Ed Engl (2005) 0.99
Synthesis of 1,8-naphthyridine C-nucleosides and their base-pairing properties in oligodeoxynucleotides: thermally stable naphthyridine:imidazopyridopyrimidine base-pairing motifs. Angew Chem Int Ed Engl (2005) 0.99
Clinical outcome and histologic findings of costal osteochondral grafts for cartilage defects in finger joints. J Hand Surg Am (2008) 0.99
Risk factors for acute suppurative cholangitis caused by bile duct stones. Eur J Gastroenterol Hepatol (2007) 0.99
Antigenic, genetic, and pathogenic characterization of H5N1 highly pathogenic avian influenza viruses isolated from dead whooper swans (Cygnus cygnus) found in northern Japan in 2008. Virus Genes (2010) 0.99
RNA interference induced by siRNAs modified with 4'-thioribonucleosides in cultured mammalian cells. FEBS Lett (2005) 0.99
Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase. Structure (2004) 0.97
Restoration of the intrinsic properties of human dermal papilla in vitro. J Cell Sci (2012) 0.97
Periostin promotes the generation of fibrous membranes in proliferative vitreoretinopathy. FASEB J (2013) 0.97
Sensitivity of human cancer cells to the new anticancer ribo-nucleoside TAS-106 is correlated with expression of uridine-cytidine kinase 2. Jpn J Cancer Res (2002) 0.97
Newly designed large cell Niti-S stent for malignant hilar biliary obstruction: a pilot study. Surg Endosc (2010) 0.97
Characterization of Staphylococcus aureus isolates from faecal samples of the Straw-Coloured Fruit Bat (Eidolon helvum) in Obafemi Awolowo University (OAU), Nigeria. BMC Microbiol (2012) 0.96
Acoustic radiation force impulse elastography for noninvasive assessment of chronic pancreatitis. J Gastroenterol (2011) 0.96
Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species. Gene (2004) 0.96
Long-term responses and outcomes following immunosuppressive therapy in large granular lymphocyte leukemia-associated pure red cell aplasia: a Nationwide Cohort Study in Japan for the PRCA Collaborative Study Group. Haematologica (2008) 0.96
Synthetic routes toward carborane-wheeled nanocars. J Org Chem (2007) 0.94
A large volume of visceral adipose tissue leads to severe acute pancreatitis. J Gastroenterol (2011) 0.94
A crucial role of uridine/cytidine kinase 2 in antitumor activity of 3'-ethynyl nucleosides. Drug Metab Dispos (2004) 0.94
Impact of S-1 in patients with gemcitabine-refractory pancreatic cancer in Japan. Jpn J Clin Oncol (2010) 0.94
Association of the IL12RB1 promoter polymorphisms with increased risk of atopic dermatitis and other allergic phenotypes. Hum Mol Genet (2005) 0.94
Mechanistic analysis of muraymycin analogues: a guide to the design of MraY inhibitors. J Med Chem (2011) 0.94