Published in Blood on August 14, 2003
Platelet bioreactor-on-a-chip. Blood (2014) 1.87
The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. Blood (2007) 1.64
The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis. Blood (2006) 1.48
Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice. Cell Res (2011) 1.48
Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells. J Exp Med (2008) 1.19
Autologous blood cell therapies from pluripotent stem cells. Blood Rev (2009) 1.09
Challenges and promises for the development of donor-independent platelet transfusions. Blood (2013) 1.09
Prolonged continuous in vitro human platelet production using three-dimensional scaffolds. Exp Hematol (2008) 1.07
In vitro megakaryocyte production and platelet biogenesis: state of the art. Transfus Med Rev (2010) 1.07
Historical perspective and future directions in platelet research. J Thromb Haemost (2011) 1.06
Distinct Sources of Hematopoietic Progenitors Emerge before HSCs and Provide Functional Blood Cells in the Mammalian Embryo. Cell Rep (2015) 1.01
Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/Maf. Blood (2012) 0.99
Knockdown of Pu.1 by small interfering RNA in CD34+ embryoid body cells derived from mouse ES cells turns cell fate determination to pro-B cells. Proc Natl Acad Sci U S A (2005) 0.94
Designer blood: creating hematopoietic lineages from embryonic stem cells. Blood (2005) 0.93
Induced pluripotent stem cell-derived human platelets: one step closer to the clinic. J Exp Med (2010) 0.90
Generation of megakaryocytic progenitors from human embryonic stem cells in a feeder- and serum-free medium. PLoS One (2013) 0.90
Lymphoid progenitor emergence in the murine embryo and yolk sac precedes stem cell detection. Stem Cells Dev (2014) 0.89
Pluripotent stem cells reveal the developmental biology of human megakaryocytes and provide a source of platelets for clinical application. Cell Mol Life Sci (2012) 0.84
Human endometrial stromal stem cells differentiate into megakaryocytes with the ability to produce functional platelets. PLoS One (2012) 0.84
Challenges and strategies for generating therapeutic patient-specific hemangioblasts and hematopoietic stem cells from human pluripotent stem cells. Int J Dev Biol (2010) 0.83
Multiple ETS family proteins regulate PF4 gene expression by binding to the same ETS binding site. PLoS One (2011) 0.82
Separation of in-vitro-derived megakaryocytes and platelets using spinning-membrane filtration. Biotechnol Bioeng (2014) 0.81
A Microfluidic Study of Megakaryocytes Membrane Transport Properties to Water and Dimethyl Sulfoxide at Suprazero and Subzero Temperatures. Biopreserv Biobank (2011) 0.79
OP9 bone marrow stroma cells differentiate into megakaryocytes and platelets. PLoS One (2013) 0.78
Modeling murine yolk sac hematopoiesis with embryonic stem cell culture systems. Front Biol (Beijing) (2014) 0.75
Advances in cellular technology in the hematology field: What have we learned so far? World J Stem Cells (2015) 0.75
Platelet generation in vivo and in vitro. Springerplus (2016) 0.75
SDF-1 directs megakaryocyte relocation. Blood (2014) 0.75
Megakaryocyte Polyploidization and Proplatelet Formation in Low-Attachment Conditions. Biochem Eng J (2016) 0.75
Mutations of optineurin in amyotrophic lateral sclerosis. Nature (2010) 4.54
Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche. Cell Stem Cell (2007) 4.31
Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders. Mol Brain (2008) 2.55
Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats. Stroke (2009) 2.37
Familial essential thrombocythemia associated with a dominant-positive activating mutation of the c-MPL gene, which encodes for the receptor for thrombopoietin. Blood (2004) 2.27
The ALG-2-interacting protein Alix associates with CHMP4b, a human homologue of yeast Snf7 that is involved in multivesicular body sorting. J Biol Chem (2003) 2.19
Basophils play a critical role in the development of IgE-mediated chronic allergic inflammation independently of T cells and mast cells. Immunity (2005) 2.19
Determinants of poor outcome after aneurysmal subarachnoid hemorrhage when both clipping and coiling are available: Prospective Registry of Subarachnoid Aneurysms Treatment (PRESAT) in Japan. World Neurosurg (2011) 2.13
Evaluation of the hematoma consequences, neurobehavioral profiles, and histopathology in a rat model of pontine hemorrhage. J Neurosurg (2012) 2.02
Characteristic air temperature distributions observed in summer and winter in urban area in Japan. Environ Monit Assess (2006) 2.01
Isoflurane delays the development of early brain injury after subarachnoid hemorrhage through sphingosine-related pathway activation in mice. Crit Care Med (2012) 1.78
Design of efficient thermally activated delayed fluorescence materials for pure blue organic light emitting diodes. J Am Chem Soc (2012) 1.68
Role of interleukin-1beta in early brain injury after subarachnoid hemorrhage in mice. Stroke (2009) 1.63
Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats. Crit Care Med (2012) 1.60
Efficient green thermally activated delayed fluorescence (TADF) from a phenoxazine-triphenyltriazine (PXZ-TRZ) derivative. Chem Commun (Camb) (2012) 1.56
Interpretation of reverse redistribution of 99mTc-tetrofosmin in patients with acute myocardial infarction. Eur J Nucl Med Mol Imaging (2002) 1.54
Clot retraction is mediated by factor XIII-dependent fibrin-αIIbβ3-myosin axis in platelet sphingomyelin-rich membrane rafts. Blood (2013) 1.48
Involvement of gangliosides in the process of Cbp/PAG phosphorylation by Lyn in developing cerebellar growth cones. J Neurochem (2013) 1.44
Thrombopoietin-producing hepatocellular carcinoma. Intern Med (2003) 1.42
Human platelets promote liver regeneration with Kupffer cells in SCID mice. J Surg Res (2012) 1.42
b-series Ganglioside deficiency exhibits no definite changes in the neurogenesis and the sensitivity to Fas-mediated apoptosis but impairs regeneration of the lesioned hypoglossal nerve. J Biol Chem (2001) 1.38
Reversal of hippocampal neuronal maturation by serotonergic antidepressants. Proc Natl Acad Sci U S A (2010) 1.37
Potent activation of RhoA by Galpha q and Gq-coupled receptors. J Biol Chem (2002) 1.35
Deficiency of schnurri-2, an MHC enhancer binding protein, induces mild chronic inflammation in the brain and confers molecular, neuronal, and behavioral phenotypes related to schizophrenia. Neuropsychopharmacology (2013) 1.33
NGF and GDNF differentially regulate TRPV1 expression that contributes to development of inflammatory thermal hyperalgesia. Eur J Neurosci (2004) 1.24
Preservation of tropomyosin-related kinase B (TrkB) signaling by sodium orthovanadate attenuates early brain injury after subarachnoid hemorrhage in rats. Stroke (2010) 1.22
Apoptotic mechanisms for neuronal cells in early brain injury after subarachnoid hemorrhage. Acta Neurochir Suppl (2011) 1.21
PDGFR-α inhibition preserves blood-brain barrier after intracerebral hemorrhage. Ann Neurol (2011) 1.19
Laminin alpha5 is required for dental epithelium growth and polarity and the development of tooth bud and shape. J Biol Chem (2005) 1.17
Keratin down-regulation in vimentin-positive cancer cells is reversible by vimentin RNA interference, which inhibits growth and motility. Mol Cancer Ther (2008) 1.14
Low wall shear stress is independently associated with the rupture status of middle cerebral artery aneurysms. Stroke (2012) 1.13
Takotsubo cardiomyopathy during acute adrenal crisis due to isolated adrenocorticotropin deficiency. Intern Med (2009) 1.11
WAVE/Scars in platelets. Blood (2004) 1.09
Neural differentiation of adipose-derived stem cells isolated from GFP transgenic mice. Biochem Biophys Res Commun (2005) 1.08
Isoflurane attenuates blood-brain barrier disruption in ipsilateral hemisphere after subarachnoid hemorrhage in mice. Stroke (2012) 1.08
α7 nicotinic acetylcholine receptor agonist PNU-282987 attenuates early brain injury in a perforation model of subarachnoid hemorrhage in rats. Stroke (2011) 1.07
Prior immunization with severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) nucleocapsid protein causes severe pneumonia in mice infected with SARS-CoV. J Immunol (2008) 1.07
Low serum levels of brain-derived neurotrophic factor and epidermal growth factor in patients with chronic schizophrenia. Schizophr Res (2008) 1.07
Functional phenotype of phosphoinositide 3-kinase p85alpha-null platelets characterized by an impaired response to GP VI stimulation. Blood (2003) 1.07
Role for EPS8 in squamous carcinogenesis. Carcinogenesis (2008) 1.06
Chronic fluoxetine bidirectionally modulates potentiating effects of serotonin on the hippocampal mossy fiber synaptic transmission. J Neurosci (2008) 1.05
Osteopontin reduced hypoxia-ischemia neonatal brain injury by suppression of apoptosis in a rat pup model. Stroke (2011) 1.05
Craniofacial malformation in R-spondin2 knockout mice. Biochem Biophys Res Commun (2009) 1.05
Non-proteolytic functions of calpain-3 in sarcoplasmic reticulum in skeletal muscles. J Mol Biol (2011) 1.05
Expression changes of cation chloride cotransporters in the rat spinal cord following intraplantar formalin. Neurosci Res (2006) 1.04
Overexpressed GM1 suppresses nerve growth factor (NGF) signals by modulating the intracellular localization of NGF receptors and membrane fluidity in PC12 cells. J Biol Chem (2004) 1.03
Strangulated hernia through a defect of the broad ligament and mobile cecum: a case report. World J Gastroenterol (2006) 1.03
Gain-of-function mutant p53 upregulates CXC chemokines and enhances cell migration. Carcinogenesis (2011) 1.03
A new member of the LIM protein family binds to filamin B and localizes at stress fibers. J Biol Chem (2002) 1.03
Calpain 8/nCL-2 and calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense. PLoS Genet (2010) 1.03
Augmented autocrine bone morphogenic protein (BMP) 7 signaling increases the metastatic potential of mouse breast cancer cells. Clin Exp Metastasis (2012) 1.02
Highly sensitive analysis of sterol profiles in human serum by LC-ESI-MS/MS. J Lipid Res (2008) 1.02
Thrombin inhibition by argatroban ameliorates early brain injury and improves neurological outcomes after experimental subarachnoid hemorrhage in rats. Stroke (2009) 1.01
Inhibition of basic leucine zipper transcription is a major mediator of atrial dilatation. Cardiovasc Res (2006) 1.01
Highly sensitive quantification of 7alpha-hydroxy-4-cholesten-3-one in human serum by LC-ESI-MS/MS. J Lipid Res (2006) 1.00
Adenovirus-mediated overexpression of caveolin-3 inhibits rat cardiomyocyte hypertrophy. Hypertension (2003) 1.00
Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment. Proc Natl Acad Sci U S A (2004) 1.00
Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy. J Clin Invest (2010) 0.99
Effects of pegylated recombinant human megakaryocyte growth and development factor in patients with idiopathic thrombocytopenic purpura. Blood (2002) 0.99
Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/Maf. Blood (2012) 0.99
Overexpression of ganglioside GM1 results in the dispersion of platelet-derived growth factor receptor from glycolipid-enriched microdomains and in the suppression of cell growth signals. J Biol Chem (2002) 0.99
The penta-EF-hand protein ALG-2 interacts directly with the ESCRT-I component TSG101, and Ca2+-dependently co-localizes to aberrant endosomes with dominant-negative AAA ATPase SKD1/Vps4B. Biochem J (2005) 0.99
miR-7a alleviates the maintenance of neuropathic pain through regulation of neuronal excitability. Brain (2013) 0.99
Chemokine CCL2/MCP-1 negatively regulates metastasis in a highly bone marrow-metastatic mouse breast cancer model. Clin Exp Metastasis (2009) 0.99
Roles of CXCL8 in squamous cell carcinoma proliferation and migration. Oral Oncol (2008) 0.98
Development of an optical fiber SPR sensor for living cell activation. Biosens Bioelectron (2009) 0.98
Highly efficient organic light-emitting diode based on a hidden thermally activated delayed fluorescence channel in a heptazine derivative. Adv Mater (2013) 0.98
Role of Porphyromonas gingivalis FeoB2 in metal uptake and oxidative stress protection. Infect Immun (2006) 0.98
An ultrastructural study of Porphyromonas gingivalis-induced platelet aggregation. Thromb Res (2008) 0.98
VEGF-C contributes to head and neck squamous cell carcinoma growth and motility. Oral Oncol (2010) 0.97
Identification of erythropoietin-induced microRNAs in haematopoietic cells during erythroid differentiation. Br J Haematol (2008) 0.96
Quantitative analyses of expression of GDNF and neurotrophins during postnatal development in rat skeletal muscles. Neurosci Res (2003) 0.96
Minocycline improves functional outcomes, memory deficits, and histopathology after endovascular perforation-induced subarachnoid hemorrhage in rats. J Neurotrauma (2011) 0.95
Prenatal dexamethasone exposure affects anxiety-like behaviour and neuroendocrine systems in an age-dependent manner. Neurosci Res (2007) 0.95
Dopamine selectively potentiates hippocampal mossy fiber to CA3 synaptic transmission. Neuropharmacology (2006) 0.95
Brap2 functions as a cytoplasmic retention protein for p21 during monocyte differentiation. Mol Cell Biol (2004) 0.95
Midline lumbar fusion with cortical bone trajectory screw. Neurol Med Chir (Tokyo) (2014) 0.94
Metabotropic P2Y purinoceptor-mediated presynaptic and postsynaptic enhancement of cerebellar GABAergic transmission. J Neurosci (2005) 0.93
The prolonged analgesic effect of epidural ropivacaine in a rat model of neuropathic pain. Anesth Analg (2008) 0.93
Caspase-1 inhibitor prevents neurogenic pulmonary edema after subarachnoid hemorrhage in mice. Stroke (2009) 0.93
Characterization of the brain injury, neurobehavioral profiles, and histopathology in a rat model of cerebellar hemorrhage. Exp Neurol (2010) 0.93
Shwachman-Diamond syndrome is not necessary for the terminal maturation of neutrophils but is important for maintaining viability of granulocyte precursors. Exp Hematol (2007) 0.93
Foot shock stress prolongs the telogen stage of the spontaneous hair cycle in a non-depilated mouse model. Exp Dermatol (2007) 0.92
Thrombospondin-bound integrin-associated protein (CD47) physically and functionally modifies integrin alphaIIbbeta3 by its extracellular domain. J Biol Chem (2003) 0.92
Autoantibody to c-Mpl (thrombopoietin receptor) in systemic lupus erythematosus: relationship to thrombocytopenia with megakaryocytic hypoplasia. Arthritis Rheum (2002) 0.91
Heat shock protein 70 upregulation by geldanamycin reduces brain injury in a mouse model of intracerebral hemorrhage. Neurochem Int (2010) 0.91
Potent transforming activity of the small GTP-binding protein Rit in NIH 3T3 cells: evidence for a role of a p38gamma-dependent signaling pathway. FEBS Lett (2002) 0.91
Thrombopoietin in postoperative thrombocytopenia following living donor hepatectomy. Liver Transpl (2006) 0.91
Imatinib mesylate prevents cerebral vasospasm after subarachnoid hemorrhage via inhibiting tenascin-C expression in rats. Neurobiol Dis (2012) 0.91
Chronic fluoxetine selectively upregulates dopamine D₁-like receptors in the hippocampus. Neuropsychopharmacology (2012) 0.90
Immune response to CagA protein is associated with improved platelet count after Helicobacter pylori eradication in patients with idiopathic thrombocytopenic purpura. Helicobacter (2007) 0.90
Interferon-alpha 2b-induced thrombocytopenia is caused by inhibition of platelet production but not proliferation and endomitosis in human megakaryocytes. Blood (2008) 0.90
Role of substance P in stress-derived degranulation of dermal mast cells in mice. J Dermatol Sci (2006) 0.90
Polymorphisms in genes involved in inflammatory pathways in patients with sudden sensorineural hearing loss. J Neurogenet (2012) 0.90
MRI findings of malignant transformation of epidermoid cyst: case report. J Neurooncol (2006) 0.90
Behavioral destabilization induced by the selective serotonin reuptake inhibitor fluoxetine. Mol Brain (2011) 0.90
Chronic stress enhances synaptic plasticity due to disinhibition in the anterior cingulate cortex and induces hyper-locomotion in mice. Neuropharmacology (2009) 0.89
Electrophysiological and pharmacological properties of GABAergic cells in the dorsal raphe nucleus. J Physiol Sci (2012) 0.89