Published in Mol Biol Cell on August 22, 2003
Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2. Mol Cell (2007) 4.22
Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells. Cell (2009) 3.95
The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis. Mol Biol Cell (2004) 2.63
A role for Rab5 in structuring the endoplasmic reticulum. J Cell Biol (2007) 2.34
A protein domain-based interactome network for C. elegans early embryogenesis. Cell (2008) 2.23
Structural evidence for common ancestry of the nuclear pore complex and vesicle coats. Science (2008) 2.15
The C9orf72 repeat expansion disrupts nucleocytoplasmic transport. Nature (2015) 2.11
The nuclear pore complex has entered the atomic age. Structure (2009) 2.07
Caenorhabditis elegans BAF-1 and its kinase VRK-1 participate directly in post-mitotic nuclear envelope assembly. EMBO J (2006) 1.81
A microtubule-independent role for centrosomes and aurora a in nuclear envelope breakdown. Dev Cell (2007) 1.81
Structural and functional analysis of Nup133 domains reveals modular building blocks of the nuclear pore complex. J Cell Biol (2004) 1.71
Integral nuclear pore proteins bind to Pol III-transcribed genes and are required for Pol III transcript processing in C. elegans. Mol Cell (2013) 1.58
The Arabidopsis SUPPRESSOR OF AUXIN RESISTANCE proteins are nucleoporins with an important role in hormone signaling and development. Plant Cell (2006) 1.52
Vertebrate Nup53 interacts with the nuclear lamina and is required for the assembly of a Nup93-containing complex. Mol Biol Cell (2005) 1.49
An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer. Cell (2016) 1.49
Systematic deletion and mitotic localization of the nuclear pore complex proteins of Aspergillus nidulans. Mol Biol Cell (2006) 1.48
Reorganization of the nuclear envelope during open mitosis. Curr Opin Cell Biol (2008) 1.46
Nuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryo. Dev Cell (2008) 1.46
Targeting Homologous Recombination in Notch-Driven C. elegans Stem Cell and Human Tumors. PLoS One (2015) 1.39
Nup155 regulates nuclear envelope and nuclear pore complex formation in nematodes and vertebrates. EMBO J (2005) 1.39
P granules extend the nuclear pore complex environment in the C. elegans germ line. J Cell Biol (2011) 1.34
The nucleoporin Nup188 controls passage of membrane proteins across the nuclear pore complex. J Cell Biol (2010) 1.33
Nup53 is required for nuclear envelope and nuclear pore complex assembly. Mol Biol Cell (2008) 1.29
The fission yeast Nup107-120 complex functionally interacts with the small GTPase Ran/Spi1 and is required for mRNA export, nuclear pore distribution, and proper cell division. Mol Cell Biol (2004) 1.27
Versatility at the nuclear pore complex: lessons learned from the nucleoporin Nup153. Chromosoma (2005) 1.27
The nucleoporins Nup170p and Nup157p are essential for nuclear pore complex assembly. J Cell Biol (2009) 1.24
Molecular architecture of the Nup84-Nup145C-Sec13 edge element in the nuclear pore complex lattice. Nat Struct Mol Biol (2009) 1.23
The dynamics of replication licensing in live Caenorhabditis elegans embryos. J Cell Biol (2012) 1.11
Dual lipid modification of Arabidopsis Ggamma-subunits is required for efficient plasma membrane targeting. Plant Physiol (2007) 1.08
Nuclear accumulation of plasmid DNA can be enhanced by non-selective gating of the nuclear pore. Nucleic Acids Res (2007) 1.03
The nucleoporin Nup153 affects spindle checkpoint activity due to an association with Mad1. Nucleus (2011) 1.03
Nuclear pore complexes: guardians of the nuclear genome. Cold Spring Harb Symp Quant Biol (2011) 1.02
Structure, dynamics, evolution, and function of a major scaffold component in the nuclear pore complex. Structure (2013) 1.00
Nucleoporins NPP-1, NPP-3, NPP-4, NPP-11 and NPP-13 are required for proper spindle orientation in C. elegans. Dev Biol (2005) 1.00
The C. elegans homolog of nucleoporin Nup98 is required for the integrity and function of germline P granules. Development (2010) 0.98
The Nuclear Pore Complex as a Flexible and Dynamic Gate. Cell (2016) 0.98
Dissection of the NUP107 nuclear pore subcomplex reveals a novel interaction with spindle assembly checkpoint protein MAD1 in Caenorhabditis elegans. Mol Biol Cell (2012) 0.98
Specific nucleoporin requirement for Smad nuclear translocation. Mol Cell Biol (2010) 0.98
Centrosome attachment to the C. elegans male pronucleus is dependent on the surface area of the nuclear envelope. Dev Biol (2009) 0.98
Multiple mechanisms actively target the SUN protein UNC-84 to the inner nuclear membrane. Mol Biol Cell (2011) 0.97
RAE-1, a novel PHR binding protein, is required for axon termination and synapse formation in Caenorhabditis elegans. J Neurosci (2012) 0.97
Dimerization and direct membrane interaction of Nup53 contribute to nuclear pore complex assembly. EMBO J (2012) 0.96
Two structurally distinct domains of the nucleoporin Nup170 cooperate to tether a subset of nucleoporins to nuclear pores. J Cell Biol (2009) 0.94
A broad requirement for TLS polymerases η and κ, and interacting sumoylation and nuclear pore proteins, in lesion bypass during C. elegans embryogenesis. PLoS Genet (2012) 0.93
A novel function for the Caenorhabditis elegans torsin OOC-5 in nucleoporin localization and nuclear import. Mol Biol Cell (2015) 0.92
Localized accumulation of tubulin during semi-open mitosis in the Caenorhabditis elegans embryo. Mol Biol Cell (2012) 0.92
A Nucleoporin Docks Protein Phosphatase 1 to Direct Meiotic Chromosome Segregation and Nuclear Assembly. Dev Cell (2016) 0.89
The C-terminal domain of Nup93 is essential for assembly of the structural backbone of nuclear pore complexes. Mol Biol Cell (2011) 0.88
Live imaging and modeling of inner nuclear membrane targeting reveals its molecular requirements in mammalian cells. J Cell Biol (2015) 0.87
Spatial control of phospholipid flux restricts endoplasmic reticulum sheet formation to allow nuclear envelope breakdown. Genes Dev (2014) 0.86
Characterization of nuclear pore complex components in fission yeast Schizosaccharomyces pombe. Nucleus (2014) 0.86
Identification of Conserved MEL-28/ELYS Domains with Essential Roles in Nuclear Assembly and Chromosome Segregation. PLoS Genet (2016) 0.86
LONO1 encoding a nucleoporin is required for embryogenesis and seed viability in Arabidopsis. Plant Physiol (2012) 0.86
Components of the Arabidopsis nuclear pore complex play multiple diverse roles in control of plant growth. J Exp Bot (2014) 0.86
NPP-16/Nup50 function and CDK-1 inactivation are associated with anoxia-induced prophase arrest in Caenorhabditis elegans. Mol Biol Cell (2010) 0.85
The nucleoporin Nup205/NPP-3 is lost near centrosomes at mitotic onset and can modulate the timing of this process in Caenorhabditis elegans embryos. Mol Biol Cell (2012) 0.85
Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C. elegans Embryos. Cell Rep (2015) 0.84
Nuclear envelope and genome interactions in cell fate. Front Genet (2015) 0.81
Worming our way in and out of the Caenorhabditis elegans germline and developing embryo. Traffic (2013) 0.80
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PUF-8 and TCER-1 are essential for normal levels of multiple mRNAs in the C. elegans germline. Development (2013) 0.79
Post-translational O-GlcNAcylation is essential for nuclear pore integrity and maintenance of the pore selectivity filter. J Mol Cell Biol (2015) 0.79
The Structure Inventory of the Nuclear Pore Complex. J Mol Biol (2016) 0.78
Uncovering buffered pleiotropy: a genome-scale screen for mel-28 genetic interactors in Caenorhabditis elegans. G3 (Bethesda) (2014) 0.78
Interaction of adenovirus type 5 E4orf4 with the nuclear pore subunit Nup205 is required for proper viral gene expression. J Virol (2014) 0.78
Sm protein down-regulation leads to defects in nuclear pore complex disassembly and distribution in C. elegans embryos. Dev Biol (2012) 0.78
N-glycosylation is required for secretion and mitosis in C. elegans. PLoS One (2013) 0.77
Proteomic Analysis of the Peri-Infarct Area after Human Umbilical Cord Mesenchymal Stem Cell Transplantation in Experimental Stroke. Aging Dis (2016) 0.77
Functional Interplay of Two Paralogs Encoding SWI/SNF Chromatin-Remodeling Accessory Subunits During Caenorhabditis elegans Development. Genetics (2016) 0.77
Nuclear assembly as a target for anti-cancer therapies. Nucleus (2014) 0.76
Cell Biology of the Caenorhabditis elegans Nucleus. Genetics (2017) 0.75
Identification and analysis of LNO1-like and AtGLE1-like nucleoporins in plants. Plant Signal Behav (2013) 0.75
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature (2003) 26.58
Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature (2000) 15.98
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Creation of low-copy integrated transgenic lines in Caenorhabditis elegans. Genetics (2001) 10.29
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Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III. Nature (2000) 9.82
Proteomic analysis of the mammalian nuclear pore complex. J Cell Biol (2002) 6.38
Large-scale analysis of gene function in Caenorhabditis elegans by high-throughput RNAi. Curr Biol (2001) 6.05
Identification and cloning of unc-119, a gene expressed in the Caenorhabditis elegans nervous system. Genetics (1995) 5.33
A novel complex of nucleoporins, which includes Sec13p and a Sec13p homolog, is essential for normal nuclear pores. Cell (1996) 4.37
Open-reading-frame sequence tags (OSTs) support the existence of at least 17,300 genes in C. elegans. Nat Genet (2001) 4.03
Nuclear pore complex contains a family of glycoproteins that includes p62: glycosylation through a previously unidentified cellular pathway. Proc Natl Acad Sci U S A (1987) 3.95
The conserved Nup107-160 complex is critical for nuclear pore complex assembly. Cell (2003) 3.58
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Gene clustering based on RNAi phenotypes of ovary-enriched genes in C. elegans. Curr Biol (2002) 3.30
An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells. J Cell Biol (2001) 3.26
Nuclear architecture and spatial positioning help establish transcriptional states of telomeres in yeast. Nat Cell Biol (2002) 3.16
Nucleocytoplasmic transport enters the atomic age. Curr Opin Cell Biol (2001) 3.06
Removal of a single pore subcomplex results in vertebrate nuclei devoid of nuclear pores. Mol Cell (2003) 3.01
Spindle dynamics and the role of gamma-tubulin in early Caenorhabditis elegans embryos. Mol Biol Cell (2001) 2.87
A conserved biogenesis pathway for nucleoporins: proteolytic processing of a 186-kilodalton precursor generates Nup98 and the novel nucleoporin, Nup96. J Cell Biol (1999) 2.76
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The nucleoporin Nup153 is required for nuclear pore basket formation, nuclear pore complex anchoring and import of a subset of nuclear proteins. EMBO J (2001) 2.14
The cytoplasmic filaments of the nuclear pore complex are dispensable for selective nuclear protein import. J Cell Biol (2002) 2.13
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Depletion of a single nucleoporin, Nup107, prevents the assembly of a subset of nucleoporins into the nuclear pore complex. Proc Natl Acad Sci U S A (2003) 2.09
Nup93, a vertebrate homologue of yeast Nic96p, forms a complex with a novel 205-kDa protein and is required for correct nuclear pore assembly. Mol Biol Cell (1997) 2.08
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The many functions of SMC proteins in chromosome dynamics. Nat Rev Mol Cell Biol (2002) 1.80
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A human condensin complex containing hCAP-C-hCAP-E and CNAP1, a homolog of Xenopus XCAP-D2, colocalizes with phosphorylated histone H3 during the early stage of mitotic chromosome condensation. Mol Cell Biol (2000) 1.73
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Nuclear envelope breakdown in starfish oocytes proceeds by partial NPC disassembly followed by a rapidly spreading fenestration of nuclear membranes. J Cell Biol (2003) 1.52
Two-color GFP expression system for C. elegans. Biotechniques (1999) 1.47
A targeted RNAi screen for genes involved in chromosome morphogenesis and nuclear organization in the Caenorhabditis elegans germline. Genetics (2002) 1.35
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Transmission electron microscope studies of the nuclear envelope in Caenorhabditis elegans embryos. J Struct Biol (2002) 1.20
Novel role for a Saccharomyces cerevisiae nucleoporin, Nup170p, in chromosome segregation. Genetics (2001) 1.18
Identification of a new vertebrate nucleoporin, Nup188, with the use of a novel organelle trap assay. Mol Biol Cell (2000) 1.17
Nuclear pore protein gp210 is essential for viability in HeLa cells and Caenorhabditis elegans. Mol Biol Cell (2003) 1.03
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Pushing the envelope: structure, function, and dynamics of the nuclear periphery. Annu Rev Cell Dev Biol (2005) 2.95
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Step-wise methylation of histone H3K9 positions heterochromatin at the nuclear periphery. Cell (2012) 2.67
MEL-28/ELYS is required for the recruitment of nucleoporins to chromatin and postmitotic nuclear pore complex assembly. EMBO Rep (2007) 2.18
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Large-scale induced fit recognition of an m(7)GpppG cap analogue by the human nuclear cap-binding complex. EMBO J (2002) 2.10
RanGTP mediates nuclear pore complex assembly. Nature (2003) 2.08
The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly. Nat Cell Biol (2002) 2.05
The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells. Mol Cell (2006) 2.04
The integral membrane nucleoporin pom121 functionally links nuclear pore complex assembly and nuclear envelope formation. Mol Cell (2005) 1.85
Caenorhabditis elegans BAF-1 and its kinase VRK-1 participate directly in post-mitotic nuclear envelope assembly. EMBO J (2006) 1.81
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Ran GTPase cycle and importins alpha and beta are essential for spindle formation and nuclear envelope assembly in living Caenorhabditis elegans embryos. Mol Biol Cell (2002) 1.69
Direct membrane protein-DNA interactions required early in nuclear envelope assembly. J Cell Biol (2006) 1.46
Nup155 regulates nuclear envelope and nuclear pore complex formation in nematodes and vertebrates. EMBO J (2005) 1.39
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NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules. Mol Biol Cell (2006) 1.37
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Nup53 is required for nuclear envelope and nuclear pore complex assembly. Mol Biol Cell (2008) 1.29
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Coordination of kinase and phosphatase activities by Lem4 enables nuclear envelope reassembly during mitosis. Cell (2012) 1.19
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The Nup107-160 nucleoporin complex promotes mitotic events via control of the localization state of the chromosome passenger complex. Mol Biol Cell (2009) 1.15
Importin alpha associates with membranes and participates in nuclear envelope assembly in vitro. EMBO J (2004) 1.14
Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate. J Cell Biol (2008) 1.13
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A compartmentalized phosphorylation/dephosphorylation system that regulates U snRNA export from the nucleus. Mol Cell Biol (2007) 0.89
Nuclear pore complexes: round the bend? Nat Cell Biol (2005) 0.89
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The nucleoporin Nup205/NPP-3 is lost near centrosomes at mitotic onset and can modulate the timing of this process in Caenorhabditis elegans embryos. Mol Biol Cell (2012) 0.85
Genome-wide analysis links emerin to neuromuscular junction activity in Caenorhabditis elegans. Genome Biol (2014) 0.85
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