Published in Mol Cell Biol on September 01, 2003
Transcription termination by nuclear RNA polymerases. Genes Dev (2009) 2.65
Gene loops enhance transcriptional directionality. Science (2012) 2.50
A role for the CPF 3'-end processing machinery in RNAP II-dependent gene looping. Genes Dev (2005) 2.49
A Requirement for the Saccharomyces cerevisiae Paf1 complex in snoRNA 3' end formation. Mol Cell (2005) 2.05
Identification of cis elements directing termination of yeast nonpolyadenylated snoRNA transcripts. Mol Cell Biol (2004) 1.81
Polyadenylation linked to transcription termination directs the processing of snoRNA precursors in yeast. Mol Cell (2008) 1.71
Biogenesis of mRNPs: integrating different processes in the eukaryotic nucleus. Chromosoma (2008) 1.69
Expanding the functional repertoire of CTD kinase I and RNA polymerase II: novel phosphoCTD-associating proteins in the yeast proteome. Biochemistry (2004) 1.68
cis- and trans-Acting determinants of transcription termination by yeast RNA polymerase II. Mol Cell Biol (2006) 1.47
cis-Proline-mediated Ser(P)5 dephosphorylation by the RNA polymerase II C-terminal domain phosphatase Ssu72. J Biol Chem (2010) 1.47
The essential WD repeat protein Swd2 has dual functions in RNA polymerase II transcription termination and lysine 4 methylation of histone H3. Mol Cell Biol (2004) 1.38
RNA polymerase II C-terminal domain: Tethering transcription to transcript and template. Chem Rev (2013) 1.35
The Ess1 prolyl isomerase is required for transcription termination of small noncoding RNAs via the Nrd1 pathway. Mol Cell (2009) 1.35
Npl3 is an antagonist of mRNA 3' end formation by RNA polymerase II. EMBO J (2005) 1.34
Properties of an intergenic terminator and start site switch that regulate IMD2 transcription in yeast. Mol Cell Biol (2008) 1.33
Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination. J Biol Chem (2012) 1.30
Functions for S. cerevisiae Swd2p in 3' end formation of specific mRNAs and snoRNAs and global histone 3 lysine 4 methylation. RNA (2004) 1.22
Yeast Nrd1, Nab3, and Sen1 transcriptome-wide binding maps suggest multiple roles in post-transcriptional RNA processing. RNA (2011) 1.17
Role for the Ssu72 C-terminal domain phosphatase in RNA polymerase II transcription elongation. Mol Cell Biol (2006) 1.17
Coupling between snoRNP assembly and 3' processing controls box C/D snoRNA biosynthesis in yeast. EMBO J (2004) 1.09
The conserved AAUAAA hexamer of the poly(A) signal can act alone to trigger a stable decrease in RNA polymerase II transcription velocity. RNA (2006) 1.08
Emerging Views on the CTD Code. Genet Res Int (2012) 1.08
A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors. EMBO J (2011) 1.04
A chromatin-based mechanism for limiting divergent noncoding transcription. Cell (2014) 1.04
Functional interaction of the Ess1 prolyl isomerase with components of the RNA polymerase II initiation and termination machineries. Mol Cell Biol (2009) 1.03
The essential N terminus of the Pta1 scaffold protein is required for snoRNA transcription termination and Ssu72 function but is dispensable for pre-mRNA 3'-end processing. Mol Cell Biol (2009) 1.02
The two steps of poly(A)-dependent termination, pausing and release, can be uncoupled by truncation of the RNA polymerase II carboxyl-terminal repeat domain. Mol Cell Biol (2004) 1.02
Identification of a role for histone H2B ubiquitylation in noncoding RNA 3'-end formation through mutational analysis of Rtf1 in Saccharomyces cerevisiae. Genetics (2011) 0.95
Nab2 functions in the metabolism of RNA driven by polymerases II and III. Mol Biol Cell (2011) 0.92
Budding yeast telomerase RNA transcription termination is dictated by the Nrd1/Nab3 non-coding RNA termination pathway. Nucleic Acids Res (2012) 0.91
A genetic screen for terminator function in yeast identifies a role for a new functional domain in termination factor Nab3. Nucleic Acids Res (2012) 0.91
Terminate and make a loop: regulation of transcriptional directionality. Trends Biochem Sci (2014) 0.91
Conserved and specific functions of mammalian ssu72. Nucleic Acids Res (2005) 0.90
The role of the Brr5/Ysh1 C-terminal domain and its homolog Syc1 in mRNA 3'-end processing in Saccharomyces cerevisiae. RNA (2006) 0.89
Human snRNA genes use polyadenylation factors to promote efficient transcription termination. Nucleic Acids Res (2013) 0.88
The role of the putative 3' end processing endonuclease Ysh1p in mRNA and snoRNA synthesis. RNA (2008) 0.87
The exosome component Rrp6 is required for RNA polymerase II termination at specific targets of the Nrd1-Nab3 pathway. PLoS Genet (2015) 0.87
Saccharomyces cerevisiae Sen1 as a model for the study of mutations in human Senataxin that elicit cerebellar ataxia. Genetics (2014) 0.85
New suppressors of THO mutations identify Thp3 (Ypr045c)-Csn12 as a protein complex involved in transcription elongation. Mol Cell Biol (2010) 0.85
Non-mRNA 3' end formation: how the other half lives. Wiley Interdiscip Rev RNA (2013) 0.84
Cryptic transcription and early termination in the control of gene expression. Genet Res Int (2011) 0.82
The Ssu72 phosphatase mediates the RNA polymerase II initiation-elongation transition. J Biol Chem (2014) 0.82
Kinase Cak1 functionally interacts with the PAF1 complex and phosphatase Ssu72 via kinases Ctk1 and Bur1. Mol Genet Genomics (2005) 0.82
Rrp47 functions in RNA surveillance and stable RNA processing when divorced from the exoribonuclease and exosome-binding domains of Rrp6. RNA (2013) 0.81
Termination of Transcription of Short Noncoding RNAs by RNA Polymerase II. Annu Rev Biochem (2015) 0.81
RNA polymerase II mutations conferring defects in poly(A) site cleavage and termination in Saccharomyces cerevisiae. G3 (Bethesda) (2013) 0.79
Transcriptional activators enhance polyadenylation of mRNA precursors. RNA Biol (2011) 0.79
Pcf11 orchestrates transcription termination pathways in yeast. Genes Dev (2015) 0.79
Nab3 facilitates the function of the TRAMP complex in RNA processing via recruitment of Rrp6 independent of Nrd1. PLoS Genet (2015) 0.78
Vertebrate Ssu72 regulates and coordinates 3'-end formation of RNAs transcribed by RNA polymerase II. PLoS One (2014) 0.76
Phosphatase Rtr1 Regulates Global Levels of Serine 5 RNA Polymerase II C-Terminal Domain Phosphorylation and Cotranscriptional Histone Methylation. Mol Cell Biol (2016) 0.76
Enhancement of Transcription by a Splicing-Competent Intron Is Dependent on Promoter Directionality. PLoS Genet (2016) 0.76
A gene-specific role for the Ssu72 RNAPII CTD phosphatase in HIV-1 Tat transactivation. Genes Dev (2014) 0.76
Context-dependent modulation of Pol II CTD phosphatase SSUP-72 regulates alternative polyadenylation in neuronal development. Genes Dev (2015) 0.76
Dephosphorylating eukaryotic RNA polymerase II. Biochim Biophys Acta (2016) 0.76
Transcriptomes of six mutants in the Sen1 pathway reveal combinatorial control of transcription termination across the Saccharomyces cerevisiae genome. PLoS Genet (2017) 0.75
Translesion synthesis DNA polymerase η exhibits a specific RNA extension activity and a transcription-associated function. Sci Rep (2017) 0.75
Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature (2002) 45.19
A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene (1987) 19.68
Formation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis. Microbiol Mol Biol Rev (1999) 11.32
Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription. Genes Dev (2000) 10.64
Integrating mRNA processing with transcription. Cell (2002) 9.74
Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution. Science (2001) 8.24
A rapid method for localized mutagenesis of yeast genes. Yeast (1992) 7.79
Transcription of eukaryotic protein-coding genes. Annu Rev Genet (2000) 6.12
Functions of the exosome in rRNA, snoRNA and snRNA synthesis. EMBO J (1999) 5.68
Opposing effects of Ctk1 kinase and Fcp1 phosphatase at Ser 2 of the RNA polymerase II C-terminal domain. Genes Dev (2001) 4.64
Yeast exosome mutants accumulate 3'-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs. Mol Cell Biol (2000) 4.57
The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins. Proc Natl Acad Sci U S A (1996) 4.16
A functional mRNA polyadenylation signal is required for transcription termination by RNA polymerase II. Genes Dev (1988) 3.80
Functional interaction of yeast pre-mRNA 3' end processing factors with RNA polymerase II. Mol Cell (2002) 3.39
A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene. Proc Natl Acad Sci U S A (1987) 3.38
RNA-binding protein Nrd1 directs poly(A)-independent 3'-end formation of RNA polymerase II transcripts. Nature (2001) 3.29
Alpha-thalassaemia caused by a poly(A) site mutation reveals that transcriptional termination is linked to 3' end processing in the human alpha 2 globin gene. EMBO J (1986) 3.25
Coupling termination of transcription to messenger RNA maturation in yeast. Science (1998) 3.09
The mRNA assembly line: transcription and processing machines in the same factory. Curr Opin Cell Biol (2002) 2.89
The RNA processing exosome is linked to elongating RNA polymerase II in Drosophila. Nature (2002) 2.77
Kin28, the TFIIH-associated carboxy-terminal domain kinase, facilitates the recruitment of mRNA processing machinery to RNA polymerase II. Mol Cell Biol (2000) 2.64
RNA processing generates the mature 3' end of yeast CYC1 messenger RNA in vitro. Science (1988) 2.62
Probabilistic prediction of Saccharomyces cerevisiae mRNA 3'-processing sites. Nucleic Acids Res (2002) 2.23
A role for SSU72 in balancing RNA polymerase II transcription elongation and termination. Mol Cell (2002) 2.06
Amino acid changes in conserved regions of the beta-subunit of Escherichia coli RNA polymerase alter transcription pausing and termination. Genes Dev (1990) 2.06
Repression of gene expression by an exogenous sequence element acting in concert with a heterogeneous nuclear ribonucleoprotein-like protein, Nrd1, and the putative helicase Sen1. Mol Cell Biol (1996) 2.02
Cleavage/polyadenylation factor IA associates with the carboxyl-terminal domain of RNA polymerase II in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2001) 1.89
Effects of alterations in the 3' flanking sequence on in vivo and in vitro expression of the yeast SUP4-o tRNATyr gene. EMBO J (1985) 1.87
A yeast heterogeneous nuclear ribonucleoprotein complex associated with RNA polymerase II. Genetics (2000) 1.86
Evolutionarily conserved interaction between CstF-64 and PC4 links transcription, polyadenylation, and termination. Mol Cell (2001) 1.85
Polyadenylation: a tail of two complexes. Curr Biol (2002) 1.83
Transcription terminates near the poly(A) site in the CYC1 gene of the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1989) 1.81
Functional interactions between the transcription and mRNA 3' end processing machineries mediated by Ssu72 and Sub1. Genes Dev (2003) 1.79
Independent functions of yeast Pcf11p in pre-mRNA 3' end processing and in transcription termination. EMBO J (2003) 1.72
SEN1, a positive effector of tRNA-splicing endonuclease in Saccharomyces cerevisiae. Mol Cell Biol (1992) 1.71
Yhh1p/Cft1p directly links poly(A) site recognition and RNA polymerase II transcription termination. EMBO J (2002) 1.71
Preparation and analysis of low molecular weight RNAs and small ribonucleoproteins. Methods Enzymol (1991) 1.62
Ssu72 is a phosphatase essential for transcription termination of snoRNAs and specific mRNAs in yeast. EMBO J (2003) 1.59
Control of pre-mRNA accumulation by the essential yeast protein Nrd1 requires high-affinity transcript binding and a domain implicated in RNA polymerase II association. Proc Natl Acad Sci U S A (1998) 1.58
Synthetic enhancement of a TFIIB defect by a mutation in SSU72, an essential yeast gene encoding a novel protein that affects transcription start site selection in vivo. Mol Cell Biol (1996) 1.51
Poly(A) signals control both transcriptional termination and initiation between the tandem GAL10 and GAL7 genes of Saccharomyces cerevisiae. EMBO J (1998) 1.50
Functional analysis of yeast snoRNA and snRNA 3'-end formation mediated by uncoupling of cleavage and polyadenylation. Mol Cell Biol (2002) 1.49
Mutational analysis of yeast TFIIB. A functional relationship between Ssu72 and Sub1/Tsp1 defined by allele-specific interactions with TFIIB. Genetics (1999) 1.48
Yeast snoRNA accumulation relies on a cleavage-dependent/polyadenylation-independent 3'-processing apparatus. EMBO J (2000) 1.47
Transcription termination by RNA polymerase III: uncoupling of polymerase release from termination signal recognition. Mol Cell Biol (1992) 1.44
The putative nucleic acid helicase Sen1p is required for formation and stability of termini and for maximal rates of synthesis and levels of accumulation of small nucleolar RNAs in Saccharomyces cerevisiae. Mol Cell Biol (1998) 1.43
Balancing transcriptional interference and initiation on the GAL7 promoter of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2000) 1.35
Orientation-dependent function of a short CYC1 DNA fragment in directing mRNA 3' end formation in yeast. Proc Natl Acad Sci U S A (1988) 1.32
The poly(A) signal, without the assistance of any downstream element, directs RNA polymerase II to pause in vivo and then to release stochastically from the template. J Biol Chem (2002) 1.30
Functional interaction between TFIIB and the Rpb9 (Ssu73) subunit of RNA polymerase II in Saccharomyces cerevisiae. Nucleic Acids Res (1996) 1.27
Functional interaction between Ssu72 and the Rpb2 subunit of RNA polymerase II in Saccharomyces cerevisiae. Mol Cell Biol (2000) 1.17
Termination-altering mutations in the second-largest subunit of yeast RNA polymerase III. Mol Cell Biol (1995) 1.09
Analysis of premature termination in c-myc during transcription by RNA polymerase II in a HeLa nuclear extract. Mol Cell Biol (1991) 1.07
Transcriptional termination factors for RNA polymerase II in yeast. Mol Cell (2001) 1.07
Saccharomyces cerevisiae RNA polymerase I terminates transcription at the Reb1 terminator in vivo. Mol Cell Biol (1999) 1.05
The mRNA transcription/processing factor Ssu72 is a potential tyrosine phosphatase. J Biol Chem (2003) 1.03
Poly(A)-driven and poly(A)-assisted termination: two different modes of poly(A)-dependent transcription termination. Mol Cell Biol (1998) 0.93
Genome-wide distribution of yeast RNA polymerase II and its control by Sen1 helicase. Mol Cell (2006) 3.46
Metal binding and base ionization in the U6 RNA intramolecular stem-loop structure. Nat Struct Biol (2002) 2.75
Regulation of a eukaryotic gene by GTP-dependent start site selection and transcription attenuation. Mol Cell (2008) 2.19
U2-U6 RNA folding reveals a group II intron-like domain and a four-helix junction. Nat Struct Mol Biol (2004) 1.66
cis- and trans-Acting determinants of transcription termination by yeast RNA polymerase II. Mol Cell Biol (2006) 1.47
Quantitative analysis of in vivo initiator selection by yeast RNA polymerase II supports a scanning model. J Biol Chem (2006) 1.46
Distinct domains of splicing factor Prp8 mediate different aspects of spliceosome activation. Proc Natl Acad Sci U S A (2002) 1.36
Structure and interactions of the first three RNA recognition motifs of splicing factor prp24. J Mol Biol (2007) 1.14
The N- and C-terminal RNA recognition motifs of splicing factor Prp24 have distinct functions in U6 RNA binding. RNA (2005) 1.04
A dynamic bulge in the U6 RNA internal stem-loop functions in spliceosome assembly and activation. RNA (2007) 1.03
A novel occluded RNA recognition motif in Prp24 unwinds the U6 RNA internal stem loop. Nucleic Acids Res (2011) 0.99
Structure and functional implications of a complex containing a segment of U6 RNA bound by a domain of Prp24. RNA (2010) 0.96
An unanticipated early function of DEAD-box ATPase Prp28 during commitment to splicing is modulated by U5 snRNP protein Prp8. RNA (2013) 0.83
Eye on RNA unwinding. Nat Struct Mol Biol (2009) 0.77
Position-dependent function of a B block promoter element implies a specialized chromatin structure on the S.cerevisiae U6 RNA gene, SNR6. Nucleic Acids Res (2004) 0.76