Published in Yeast on February 01, 1992
Wavelength mutations and posttranslational autoxidation of green fluorescent protein. Proc Natl Acad Sci U S A (1994) 10.50
The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex. EMBO J (1998) 7.83
Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures. Nat Methods (2010) 6.00
Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1p. J Cell Biol (1998) 5.21
Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates. Antimicrob Agents Chemother (2005) 4.89
Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways. J Cell Biol (2000) 4.30
A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole. J Cell Biol (1997) 4.16
Nuclear mRNA export requires complex formation between Mex67p and Mtr2p at the nuclear pores. Mol Cell Biol (1998) 3.66
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A putative protein complex consisting of Ctf19, Mcm21, and Okp1 represents a missing link in the budding yeast kinetochore. Genes Dev (1999) 3.50
The path from nucleolar 90S to cytoplasmic 40S pre-ribosomes. EMBO J (2003) 3.38
Specific retrieval of the exocytic SNARE Snc1p from early yeast endosomes. Mol Biol Cell (2000) 3.32
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Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast. J Cell Biol (1995) 3.16
Vam7p, a SNAP-25-like molecule, and Vam3p, a syntaxin homolog, function together in yeast vacuolar protein trafficking. Mol Cell Biol (1998) 2.80
Cdc34 and the F-box protein Met30 are required for degradation of the Cdk-inhibitory kinase Swe1. Genes Dev (1998) 2.75
Sld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiae. EMBO J (2001) 2.70
Novel Golgi to vacuole delivery pathway in yeast: identification of a sorting determinant and required transport component. EMBO J (1997) 2.60
Regulation of ceramide biosynthesis by TOR complex 2. Cell Metab (2008) 2.57
Interaction of the Doa4 deubiquitinating enzyme with the yeast 26S proteasome. Mol Biol Cell (1999) 2.57
Localization of core spindle pole body (SPB) components during SPB duplication in Saccharomyces cerevisiae. J Cell Biol (1999) 2.50
The yeast v-SNARE Vti1p mediates two vesicle transport pathways through interactions with the t-SNAREs Sed5p and Pep12p. J Cell Biol (1997) 2.50
Receptors determine the cellular localization of a gamma-tubulin complex and thereby the site of microtubule formation. EMBO J (1998) 2.48
Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses. J Cell Biol (2000) 2.48
The yeast synaptojanin-like proteins control the cellular distribution of phosphatidylinositol (4,5)-bisphosphate. Mol Biol Cell (2002) 2.39
The spindle pole body component Spc98p interacts with the gamma-tubulin-like Tub4p of Saccharomyces cerevisiae at the sites of microtubule attachment. EMBO J (1996) 2.39
Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism. Genetics (1998) 2.37
Apg5p functions in the sequestration step in the cytoplasm-to-vacuole targeting and macroautophagy pathways. Mol Biol Cell (2000) 2.33
Sli15 associates with the ipl1 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiae. J Cell Biol (1999) 2.32
Pbp1p, a factor interacting with Saccharomyces cerevisiae poly(A)-binding protein, regulates polyadenylation. Mol Cell Biol (1998) 2.26
Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for sub2, an essential spliceosomal ATPase. Genes Dev (2001) 2.24
A novel Sec18p/NSF-dependent complex required for Golgi-to-endosome transport in yeast. Mol Biol Cell (1997) 2.24
Control of cleavage site selection during mRNA 3' end formation by a yeast hnRNP. EMBO J (1998) 2.21
A new class of histone H2A mutations in Saccharomyces cerevisiae causes specific transcriptional defects in vivo. Mol Cell Biol (1995) 2.20
Identification of a cytoplasm to vacuole targeting determinant in aminopeptidase I. J Cell Biol (1996) 2.16
COPI-independent anterograde transport: cargo-selective ER to Golgi protein transport in yeast COPI mutants. J Cell Biol (1997) 2.16
Control of microtubule dynamics by Stu2p is essential for spindle orientation and metaphase chromosome alignment in yeast. Mol Biol Cell (2001) 2.16
Allele-specific genetic interactions between Prp8 and RNA active site residues suggest a function for Prp8 at the catalytic core of the spliceosome. Genes Dev (1999) 2.12
A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1. J Cell Biol (2004) 2.07
A Requirement for the Saccharomyces cerevisiae Paf1 complex in snoRNA 3' end formation. Mol Cell (2005) 2.05
Fal1p is an essential DEAD-box protein involved in 40S-ribosomal-subunit biogenesis in Saccharomyces cerevisiae. Mol Cell Biol (1997) 2.05
Chromatin assembly factor I mutants defective for PCNA binding require Asf1/Hir proteins for silencing. Mol Cell Biol (2002) 2.05
LST8 negatively regulates amino acid biosynthesis as a component of the TOR pathway. J Cell Biol (2003) 2.01
Sac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology. Mol Biol Cell (2001) 1.99
The recruitment of RNA polymerase I on rDNA is mediated by the interaction of the A43 subunit with Rrn3. EMBO J (2000) 1.96
Mutagenesis of the yeast gene PRP8 reveals domains governing the specificity and fidelity of 3' splice site selection. Genetics (1996) 1.94
The phosphatidylinositol 3-phosphate binding protein Vac1p interacts with a Rab GTPase and a Sec1p homologue to facilitate vesicle-mediated vacuolar protein sorting. Mol Biol Cell (1999) 1.93
Role of calmodulin and Spc110p interaction in the proper assembly of spindle pole body compenents. J Cell Biol (1996) 1.92
Mitotic chromosome condensation requires Brn1p, the yeast homologue of Barren. Mol Biol Cell (2000) 1.90
The Ess1 prolyl isomerase is linked to chromatin remodeling complexes and the general transcription machinery. EMBO J (2000) 1.88
PCF11 encodes a third protein component of yeast cleavage and polyadenylation factor I. Mol Cell Biol (1997) 1.88
Sfi1p has conserved centrin-binding sites and an essential function in budding yeast spindle pole body duplication. J Cell Biol (2003) 1.88
Rck2 kinase is a substrate for the osmotic stress-activated mitogen-activated protein kinase Hog1. Mol Cell Biol (2000) 1.87
A yeast heterogeneous nuclear ribonucleoprotein complex associated with RNA polymerase II. Genetics (2000) 1.86
Interactions between centromere complexes in Saccharomyces cerevisiae. Mol Biol Cell (2003) 1.85
PDK1 homologs activate the Pkc1-mitogen-activated protein kinase pathway in yeast. Mol Cell Biol (1999) 1.83
Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing. J Cell Biol (1998) 1.75
Genetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid system. Proc Natl Acad Sci U S A (1996) 1.72
Spc29p is a component of the Spc110p subcomplex and is essential for spindle pole body duplication. Proc Natl Acad Sci U S A (1999) 1.72
Two AAA family peroxins, PpPex1p and PpPex6p, interact with each other in an ATP-dependent manner and are associated with different subcellular membranous structures distinct from peroxisomes. Mol Cell Biol (1998) 1.66
Positive and negative regulation of a SNARE protein by control of intracellular localization. Mol Biol Cell (2004) 1.65
Evidence that Swi/Snf directly represses transcription in S. cerevisiae. Genes Dev (2002) 1.64
Ssu72 protein mediates both poly(A)-coupled and poly(A)-independent termination of RNA polymerase II transcription. Mol Cell Biol (2003) 1.64
The yeast spindle pole body component Spc72p interacts with Stu2p and is required for proper microtubule assembly. J Cell Biol (1998) 1.63
Genetic selection of intragenic suppressor mutations that reverse the effect of common p53 cancer mutations. EMBO J (1998) 1.62
Acidic di-leucine motif essential for AP-3-dependent sorting and restriction of the functional specificity of the Vam3p vacuolar t-SNARE. J Cell Biol (1998) 1.58
A region of the Sir1 protein dedicated to recognition of a silencer and required for interaction with the Orc1 protein in saccharomyces cerevisiae. Genetics (1999) 1.58
A yeast protein related to a mammalian Ras-binding protein, Vps9p, is required for localization of vacuolar proteins. Mol Cell Biol (1996) 1.56
Meiotic segregation, synapsis, and recombination checkpoint functions require physical interaction between the chromosomal proteins Red1p and Hop1p. Mol Cell Biol (2000) 1.52
Histone-histone interactions and centromere function. Mol Cell Biol (2000) 1.49
Dynamic localization of the Swe1 regulator Hsl7 during the Saccharomyces cerevisiae cell cycle. Mol Biol Cell (2001) 1.49
Requirement for a functional interaction between mediator components Med6 and Srb4 in RNA polymerase II transcription. Mol Cell Biol (1998) 1.48
Mutational analysis of yeast TFIIB. A functional relationship between Ssu72 and Sub1/Tsp1 defined by allele-specific interactions with TFIIB. Genetics (1999) 1.48
The nucleotide exchange factor Cdc24p may be regulated by auto-inhibition. EMBO J (2004) 1.44
Role of SGS1 and SLX4 in maintaining rDNA structure in Saccharomyces cerevisiae. Curr Genet (2002) 1.42
Functional expression of a fungal laccase in Saccharomyces cerevisiae by directed evolution. Appl Environ Microbiol (2003) 1.40
Use1p is a yeast SNARE protein required for retrograde traffic to the ER. EMBO J (2003) 1.40
Identification of functionally important amino acids of ribosomal protein L3 by saturation mutagenesis. Mol Cell Biol (2005) 1.39
A subcomplex of RNA polymerase III subunits involved in transcription termination and reinitiation. EMBO J (2005) 1.39
Mutational analysis of STE5 in the yeast Saccharomyces cerevisiae: application of a differential interaction trap assay for examining protein-protein interactions. Genetics (1997) 1.38
Sec61p serves multiple roles in secretory precursor binding and translocation into the endoplasmic reticulum membrane. Mol Biol Cell (1998) 1.38
Novel Gal3 proteins showing altered Gal80p binding cause constitutive transcription of Gal4p-activated genes in Saccharomyces cerevisiae. Mol Cell Biol (1997) 1.37
Residues in the WD repeats of Tup1 required for interaction with alpha2. Mol Cell Biol (1997) 1.36
In vivo analysis reveals that the interdomain region of the yeast proliferating cell nuclear antigen is important for DNA replication and DNA repair. Genetics (1996) 1.36
A mutational analysis identifies three functional regions of the spindle pole component Spc110p in Saccharomyces cerevisiae. Mol Biol Cell (1997) 1.36
Dosage suppressors of pds1 implicate ubiquitin-associated domains in checkpoint control. Mol Cell Biol (2001) 1.35
A mutational analysis of the interaction between FliG and FliM, two components of the flagellar motor of Escherichia coli. J Bacteriol (1996) 1.33
Method for generation of in vivo biotinylated recombinant antibodies by yeast mating. J Immunol Methods (2006) 1.32
Positive and negative regulation of poly(A) nuclease. Mol Cell Biol (2004) 1.32
Human RNA polymerase II subunit hsRPB7 functions in yeast and influences stress survival and cell morphology. Mol Biol Cell (1995) 1.32
The origin recognition complex and Sir4 protein recruit Sir1p to yeast silent chromatin through independent interactions requiring a common Sir1p domain. Mol Cell Biol (2004) 1.30
Stu1p is physically associated with beta-tubulin and is required for structural integrity of the mitotic spindle. Mol Biol Cell (2002) 1.30
A direct interaction between the Utp6 half-a-tetratricopeptide repeat domain and a specific peptide in Utp21 is essential for efficient pre-rRNA processing. Mol Cell Biol (2008) 1.30
Genetic analysis reveals a role for the C terminus of the Saccharomyces cerevisiae GTPase Snu114 during spliceosome activation. Genetics (2005) 1.30
A transcriptional mediator protein that is required for activation of many RNA polymerase II promoters and is conserved from yeast to humans. Mol Cell Biol (1997) 1.29
The Bbp1p-Mps2p complex connects the SPB to the nuclear envelope and is essential for SPB duplication. EMBO J (2000) 1.29
A genetic strategy to eliminate self-activator baits prior to high-throughput yeast two-hybrid screens. Genome Res (1999) 1.28
Tom40, the import channel of the mitochondrial outer membrane, plays an active role in sorting imported proteins. EMBO J (2003) 1.27
Identification of three regions essential for interaction between a sigma-like factor and core RNA polymerase. Genes Dev (1997) 1.26
A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation. Genes Dev (1993) 9.28
Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript. Genes Dev (1994) 7.57
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An essential component of the decapping enzyme required for normal rates of mRNA turnover. Nature (1996) 6.15
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Yeast Sm-like proteins function in mRNA decapping and decay. Nature (2000) 5.95
The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae. Cell (2001) 5.86
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The DCP2 protein is required for mRNA decapping in Saccharomyces cerevisiae and contains a functional MutT motif. EMBO J (1999) 5.08
The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes. RNA (2001) 4.80
Yeast exosome mutants accumulate 3'-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs. Mol Cell Biol (2000) 4.57
Mutations in translation initiation factors lead to increased rates of deadenylation and decapping of mRNAs in Saccharomyces cerevisiae. Mol Cell Biol (1999) 4.35
Mechanisms and control of mRNA turnover in Saccharomyces cerevisiae. Microbiol Rev (1996) 4.34
Mutations affecting stability and deadenylation of the yeast MFA2 transcript. Genes Dev (1992) 4.20
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Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAs in yeast. EMBO J (2000) 2.44
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