Published in Curr Biol on September 02, 2003
Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions. J Cell Biol (2010) 3.61
XMAP215 is a processive microtubule polymerase. Cell (2008) 3.33
TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly. Mol Biol Cell (2004) 2.65
Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis. J Cell Biol (2005) 2.57
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The Xenopus TACC homologue, maskin, functions in mitotic spindle assembly. Mol Biol Cell (2005) 1.25
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The mbk-2 kinase is required for inactivation of MEI-1/katanin in the one-cell Caenorhabditis elegans embryo. EMBO Rep (2003) 1.07
The microtubule lattice and plus-end association of Drosophila Mini spindles is spatially regulated to fine-tune microtubule dynamics. Mol Biol Cell (2011) 1.02
Structure-function evolution of the transforming acidic coiled coil genes revealed by analysis of phylogenetically diverse organisms. BMC Evol Biol (2004) 1.00
RACK-1 directs dynactin-dependent RAB-11 endosomal recycling during mitosis in Caenorhabditis elegans. Mol Biol Cell (2009) 0.98
XMAP215-EB1 interaction is required for proper spindle assembly and chromosome segregation in Xenopus egg extract. Mol Biol Cell (2009) 0.97
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The UBXN-2/p37/p47 adaptors of CDC-48/p97 regulate mitosis by limiting the centrosomal recruitment of Aurora A. J Cell Biol (2013) 0.95
TACC3 is a microtubule plus end-tracking protein that promotes axon elongation and also regulates microtubule plus end dynamics in multiple embryonic cell types. Mol Biol Cell (2014) 0.93
The fission yeast transforming acidic coiled coil-related protein Mia1p/Alp7p is required for formation and maintenance of persistent microtubule-organizing centers at the nuclear envelope. Mol Biol Cell (2006) 0.93
Xenopus TACC3/maskin is not required for microtubule stability but is required for anchoring microtubules at the centrosome. Mol Biol Cell (2008) 0.92
Asymmetric spindle positioning. Curr Opin Cell Biol (2005) 0.90
LET-711, the Caenorhabditis elegans NOT1 ortholog, is required for spindle positioning and regulation of microtubule length in embryos. Mol Biol Cell (2006) 0.89
Asymmetric cell divisions in the epidermis. Int Rev Cell Mol Biol (2012) 0.88
The centrosomal, putative tumor suppressor protein TACC2 is dispensable for normal development, and deficiency does not lead to cancer. Mol Cell Biol (2004) 0.88
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CLASPs function redundantly to regulate astral microtubules in the C. elegans embryo. Dev Biol (2012) 0.85
Axon injury triggers EFA-6 mediated destabilization of axonal microtubules via TACC and doublecortin like kinase. Elife (2015) 0.84
Mutations of a redundant alpha-tubulin gene affect Caenorhabditis elegans early embryonic cleavage via MEI-1/katanin-dependent and -independent pathways. Genetics (2005) 0.84
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CDK-dependent phosphorylation of Alp7-Alp14 (TACC-TOG) promotes its nuclear accumulation and spindle microtubule assembly. Mol Biol Cell (2014) 0.82
Csi1p recruits alp7p/TACC to the spindle pole bodies for bipolar spindle formation. Mol Biol Cell (2014) 0.80
A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly. Sci Rep (2015) 0.79
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Mos1-mediated transgenesis to probe consequences of single gene mutations in variation-rich isolates of Caenorhabditis elegans. PLoS One (2012) 0.75
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature (2010) 9.95
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals. Nat Methods (2008) 6.51
Germline P granules are liquid droplets that localize by controlled dissolution/condensation. Science (2009) 5.55
Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science (2010) 4.69
Dynamics and mechanics of the microtubule plus end. Nature (2003) 4.68
Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers. Cell (2010) 4.31
Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner. Nat Cell Biol (2006) 4.13
Genome-scale RNAi profiling of cell division in human tissue culture cells. Nat Cell Biol (2007) 3.91
Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis. Nature (2005) 3.62
Centriole assembly in Caenorhabditis elegans. Nature (2006) 3.58
A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell (2013) 3.53
XMAP215 is a processive microtubule polymerase. Cell (2008) 3.33
SAS-4 is a C. elegans centriolar protein that controls centrosome size. Cell (2003) 3.19
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity. Curr Biol (2009) 2.98
The distribution of active force generators controls mitotic spindle position. Science (2003) 2.97
Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells. Nat Cell Biol (2010) 2.91
Hydrostatic pressure and the actomyosin cortex drive mitotic cell rounding. Nature (2011) 2.68
Spindle oscillations during asymmetric cell division require a threshold number of active cortical force generators. Curr Biol (2006) 2.67
A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue. Cell (2011) 2.64
Microtubule polymerases and depolymerases. Curr Opin Cell Biol (2006) 2.64
RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells. Proc Natl Acad Sci U S A (2005) 2.59
Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis. J Cell Biol (2005) 2.57
Genome-wide identification of binding sites defines distinct functions for Caenorhabditis elegans PHA-4/FOXA in development and environmental response. PLoS Genet (2010) 2.46
Katanin disrupts the microtubule lattice and increases polymer number in C. elegans meiosis. Curr Biol (2006) 2.45
The Caenorhabditis elegans centrosomal protein SPD-2 is required for both pericentriolar material recruitment and centriole duplication. Curr Biol (2004) 2.44
Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes. Proc Natl Acad Sci U S A (2011) 2.44
Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegans. Genome Res (2010) 2.30
Limiting amounts of centrosome material set centrosome size in C. elegans embryos. Curr Biol (2011) 2.25
A protein domain-based interactome network for C. elegans early embryogenesis. Cell (2008) 2.23
Centrosome size sets mitotic spindle length in Caenorhabditis elegans embryos. Curr Biol (2010) 2.23
Asymmetric cell division in C. elegans: cortical polarity and spindle positioning. Annu Rev Cell Dev Biol (2004) 2.22
A cytokinesis furrow is positioned by two consecutive signals. Nature (2005) 2.21
GTP binding induces filament assembly of a recombinant septin. Curr Biol (2002) 2.16
Spindle positioning by cortical pulling forces. Dev Cell (2005) 2.14
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. EMBO J (2011) 2.14
The kinetically dominant assembly pathway for centrosomal asters in Caenorhabditis elegans is gamma-tubulin dependent. J Cell Biol (2002) 2.13
Sororin mediates sister chromatid cohesion by antagonizing Wapl. Cell (2010) 2.12
A genome-scale resource for in vivo tag-based protein function exploration in C. elegans. Cell (2012) 2.07
Identification and characterization of factors required for microtubule growth and nucleation in the early C. elegans embryo. Dev Cell (2005) 2.02
The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae. Nature (2005) 2.01
Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A. J Cell Biol (2008) 1.92
LET-99, GOA-1/GPA-16, and GPR-1/2 are required for aster-positioned cytokinesis. Curr Biol (2006) 1.91
The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis. Curr Biol (2008) 1.88
Polarization of PAR proteins by advective triggering of a pattern-forming system. Science (2011) 1.88
XMAP215: a key component of the dynamic microtubule cytoskeleton. Trends Cell Biol (2002) 1.87
Centrosomes direct cell polarity independently of microtubule assembly in C. elegans embryos. Nature (2004) 1.85
CDC-42 and RHO-1 coordinate acto-myosin contractility and PAR protein localization during polarity establishment in C. elegans embryos. Development (2006) 1.74
Organelle growth control through limiting pools of cytoplasmic components. Curr Biol (2012) 1.71
Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules. J Cell Biol (2005) 1.70
Cell division. WormBook (2006) 1.63
Growth, fluctuation and switching at microtubule plus ends. Nat Rev Mol Cell Biol (2009) 1.62
Role of mitochondria in the pheromone- and amiodarone-induced programmed death of yeast. J Cell Biol (2005) 1.57
XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region. Proc Natl Acad Sci U S A (2011) 1.56
Crystal structure of a TOG domain: conserved features of XMAP215/Dis1-family TOG domains and implications for tubulin binding. Structure (2007) 1.54
Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division. EMBO J (2009) 1.51
EB1 recognizes the nucleotide state of tubulin in the microtubule lattice. PLoS One (2009) 1.45
BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures. Mol Biol Cell (2012) 1.44
Stoichiometry of chromatin-associated protein complexes revealed by label-free quantitative mass spectrometry-based proteomics. Nucleic Acids Res (2012) 1.43
Morphologically distinct microtubule ends in the mitotic centrosome of Caenorhabditis elegans. J Cell Biol (2003) 1.42
APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex. Nat Struct Mol Biol (2012) 1.40
Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions. Cell (2012) 1.40
The C. elegans RSA complex localizes protein phosphatase 2A to centrosomes and regulates mitotic spindle assembly. Cell (2007) 1.34
Acto-myosin reorganization and PAR polarity in C. elegans. Development (2007) 1.32
Systematic phosphorylation analysis of human mitotic protein complexes. Sci Signal (2011) 1.31
Stress generation and filament turnover during actin ring constriction. PLoS One (2007) 1.31
Cell cycle progression requires the CDC-48UFD-1/NPL-4 complex for efficient DNA replication. Proc Natl Acad Sci U S A (2008) 1.29
Myosin II regulation during C. elegans embryonic elongation: LET-502/ROCK, MRCK-1 and PAK-1, three kinases with different roles. Development (2009) 1.29
The Rho GTPase-activating proteins RGA-3 and RGA-4 are required to set the initial size of PAR domains in Caenorhabditis elegans one-cell embryos. Proc Natl Acad Sci U S A (2007) 1.29
An essential function of the C. elegans ortholog of TPX2 is to localize activated aurora A kinase to mitotic spindles. Dev Cell (2005) 1.27
Synergy between XMAP215 and EB1 increases microtubule growth rates to physiological levels. Nat Cell Biol (2013) 1.27
Proliferating versus differentiating stem and cancer cells exhibit distinct midbody-release behaviour. Nat Commun (2011) 1.26
Spatial organization of the cell cytoplasm by position-dependent phase separation. Phys Rev Lett (2013) 1.22
Automated tracking and analysis of centrosomes in early Caenorhabditis elegans embryos. Bioinformatics (2010) 1.21
XMAP215 activity sets spindle length by controlling the total mass of spindle microtubules. Nat Cell Biol (2013) 1.20
LGL can partition the cortex of one-cell Caenorhabditis elegans embryos into two domains. Curr Biol (2010) 1.16
GTSE1 is a microtubule plus-end tracking protein that regulates EB1-dependent cell migration. PLoS One (2012) 1.12
A genomic toolkit to investigate kinesin and myosin motor function in cells. Nat Cell Biol (2013) 1.11
The RhoGAP RGA-2 and LET-502/ROCK achieve a balance of actomyosin-dependent forces in C. elegans epidermis to control morphogenesis. Development (2007) 1.08
The mbk-2 kinase is required for inactivation of MEI-1/katanin in the one-cell Caenorhabditis elegans embryo. EMBO Rep (2003) 1.07
Functional interaction between phosducin-like protein 2 and cytosolic chaperonin is essential for cytoskeletal protein function and cell cycle progression. Mol Biol Cell (2007) 1.06
Membrane invaginations reveal cortical sites that pull on mitotic spindles in one-cell C. elegans embryos. PLoS One (2010) 1.05
PAR proteins diffuse freely across the anterior-posterior boundary in polarized C. elegans embryos. J Cell Biol (2011) 1.04
Multiple regulatory elements with spatially and temporally distinct activities control the expression of the epithelial differentiation gene lin-26 in C. elegans. Dev Biol (2004) 1.04
One-step purification of assembly-competent tubulin from diverse eukaryotic sources. Mol Biol Cell (2012) 1.03
Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores. J Cell Biol (2012) 1.03
Cyclin E-Cdk2 temporally regulates centrosome assembly and establishment of polarity in Caenorhabditis elegans embryos. Nat Cell Biol (2006) 1.00
Efficient chaperone-mediated tubulin biogenesis is essential for cell division and cell migration in C. elegans. Dev Biol (2007) 0.99
High-efficiency counterselection recombineering for site-directed mutagenesis in bacterial artificial chromosomes. Nat Methods (2011) 0.98
Purification of tubulin from porcine brain. Methods Mol Biol (2011) 0.97
Automated tracing of microtubules in electron tomograms of plastic embedded samples of Caenorhabditis elegans embryos. J Struct Biol (2011) 0.97
Cortical domain correction repositions the polarity boundary to match the cytokinesis furrow in C. elegans embryos. Development (2010) 0.96
FRAP analysis of membrane-associated proteins: lateral diffusion and membrane-cytoplasmic exchange. Biophys J (2010) 0.94
Characterization of protein dynamics in asymmetric cell division by scanning fluorescence correlation spectroscopy. Biophys J (2008) 0.93
Tracking mechanics and volume of globular cells with atomic force microscopy using a constant-height clamp. Nat Protoc (2012) 0.91
VAB-10 spectraplakin acts in cell and nuclear migration in Caenorhabditis elegans. Development (2011) 0.90
Conserved TCP domain of Sas-4/CPAP is essential for pericentriolar material tethering during centrosome biogenesis. Proc Natl Acad Sci U S A (2014) 0.89