Interaction of DNA polymerase alpha-primase with cellular replication protein A and SV40 T antigen.

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Published in EMBO J on February 01, 1992

Authors

I Dornreiter1, L F Erdile, I U Gilbert, D von Winkler, T J Kelly, E Fanning

Author Affiliations

1: Institute for Biochemistry, Munich, Germany.

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Adenovirus origin of DNA replication: sequence requirements for replication in vitro. Mol Cell Biol (1987) 1.44

Two regions of simian virus 40 T antigen determine cooperativity of double-hexamer assembly on the viral origin of DNA replication and promote hexamer interactions during bidirectional origin DNA unwinding. J Virol (1999) 1.43

Expression of the differentiation-induced gene for fatty acid-binding protein is activated by glucocorticoid and cAMP. Proc Natl Acad Sci U S A (1988) 1.40

The structure of replicating adenovirus DNA molecules: characterization of DNA-protein complexes from infected cells. Cold Spring Harb Symp Quant Biol (1979) 1.38

Mechanism of regulation of the 422(aP2) gene by cAMP during preadipocyte differentiation. Proc Natl Acad Sci U S A (1989) 1.36

Intracellular forms of adenovirus DNA. V. Viral DNA sequences in hamster cells abortively infected and transformed with human adenovirus type 12. J Virol (1976) 1.36

Safety and immunogenicity of a recombinant outer surface protein A Lyme vaccine. JAMA (1994) 1.36

DNA polymerase alpha is associated with replicating SV40 nucleoprotein complexes. Nucleic Acids Res (1978) 1.36

Interaction of the S phase regulator cdc18 with cyclin-dependent kinase in fission yeast. Proc Natl Acad Sci U S A (1997) 1.34

Sequence-specific interactions between a cellular DNA-binding protein and the simian virus 40 origin of DNA replication. Mol Cell Biol (1988) 1.34

Cyclin-dependent kinase and initiation at eukaryotic origins: a replication switch? Curr Opin Cell Biol (1997) 1.33

Maturation of newly replicated chromatin of simian virus 40 and its host cell. J Mol Biol (1980) 1.31

Intracistronic complementation reveals a new function of SV40 T antigen that co-operates with Rb and p53 binding to stimulate DNA synthesis in quiescent cells. Oncogene (1992) 1.29