Published in Cell on January 16, 1987
Two DNA-binding factors recognize specific sequences at silencers, upstream activating sequences, autonomously replicating sequences, and telomeres in Saccharomyces cerevisiae. Mol Cell Biol (1988) 7.10
Some recent advances in the chemistry and biology of transforming growth factor-beta. J Cell Biol (1987) 5.25
Identification and purification of a polypeptide that binds to the c-fos serum response element. EMBO J (1987) 4.68
Identification and purification of a human immunoglobulin-enhancer-binding protein (NF-kappa B) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro. Proc Natl Acad Sci U S A (1988) 4.33
A relational database of transcription factors. Nucleic Acids Res (1990) 4.03
Connections between transcriptional activators, silencers, and telomeres as revealed by functional analysis of a yeast DNA-binding protein. Mol Cell Biol (1988) 3.69
Purification of a yeast protein that binds to origins of DNA replication and a transcriptional silencer. Proc Natl Acad Sci U S A (1988) 3.18
The human beta-globin promoter; nuclear protein factors and erythroid specific induction of transcription. EMBO J (1988) 3.16
A mutational analysis of the insulin gene transcription control region: expression in beta cells is dependent on two related sequences within the enhancer. Proc Natl Acad Sci U S A (1987) 3.08
Several distinct "CCAAT" box binding proteins coexist in eukaryotic cells. Proc Natl Acad Sci U S A (1988) 3.01
Purified hepatocyte nuclear factor 1 interacts with a family of hepatocyte-specific promoters. Proc Natl Acad Sci U S A (1988) 2.90
The adenovirus-inducible factor E2F stimulates transcription after specific DNA binding. Mol Cell Biol (1989) 2.83
Mutational analysis of the chicken beta-globin enhancer reveals two positive-acting domains. Proc Natl Acad Sci U S A (1988) 2.80
Purification of KBF1, a common factor binding to both H-2 and beta 2-microglobulin enhancers. EMBO J (1987) 2.71
A human cytomegalovirus early gene has three inducible promoters that are regulated differentially at various times after infection. J Virol (1989) 2.70
Cis- and trans-acting elements responsible for the cell-specific expression of the human alpha 1-antitrypsin gene. EMBO J (1987) 2.69
Purification of a NF1-like DNA-binding protein from rat liver and cloning of the corresponding cDNA. EMBO J (1988) 2.60
Four classes of mRNA are expressed from the mouse int-2 gene, a member of the FGF gene family. EMBO J (1988) 2.51
Co-evolution from yeast to mouse: cDNA cloning of the two NF-Y (CP-1/CBF) subunits. EMBO J (1990) 2.49
Roles of two DNA-binding factors in replication, segregation and transcriptional repression mediated by a yeast silencer. EMBO J (1988) 2.46
Association of the virD2 protein with the 5' end of T strands in Agrobacterium tumefaciens. J Bacteriol (1988) 2.44
Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals. Mol Cell Biol (1990) 2.41
Destabilization of simple repetitive DNA sequences by transcription in yeast. Genetics (1996) 2.39
GATAAG; a cis-control region binding an erythroid-specific nuclear factor with a role in globin and non-globin gene expression. Nucleic Acids Res (1989) 2.31
Multiple genes encode nuclear factor 1-like proteins that bind to the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Proc Natl Acad Sci U S A (1988) 2.31
Promoter interaction of the E1A-inducible factor E2F and its potential role in the formation of a multi-component complex. EMBO J (1987) 2.30
Chicken NFI/TGGCA proteins are encoded by at least three independent genes: NFI-A, NFI-B and NFI-C with homologues in mammalian genomes. Nucleic Acids Res (1990) 2.24
Activation of a preexisting cellular factor as a basis for adenovirus E1A-mediated transcription control. Proc Natl Acad Sci U S A (1988) 2.16
RAP30/74: a general initiation factor that binds to RNA polymerase II. Mol Cell Biol (1988) 2.16
DNA binding by c-Ets-1, but not v-Ets, is repressed by an intramolecular mechanism. EMBO J (1992) 2.15
Multiple early transcripts and splicing of the Autographa californica nuclear polyhedrosis virus IE-1 gene. J Virol (1988) 2.13
Systematic binding analysis of the insulin gene transcription control region: insulin and immunoglobulin enhancers utilize similar transactivators. Mol Cell Biol (1988) 2.13
In vitro activation of the HIV-1 enhancer in extracts from cells treated with a phorbol ester tumor promoter. EMBO J (1987) 2.09
Purification of intercalator-released p67, a polypeptide that interacts specifically with the c-fos serum response element. Nucleic Acids Res (1987) 2.09
Mammalian p53 can function as a transcription factor in yeast. Nucleic Acids Res (1992) 2.07
One cell-specific and three ubiquitous nuclear proteins bind in vitro to overlapping motifs in the domain B1 of the SV40 enhancer. EMBO J (1987) 2.04
Interaction of the TGGCA-binding protein with upstream sequences is required for efficient transcription of mouse mammary tumor virus. EMBO J (1987) 2.04
A yeast ARS-binding protein activates transcription synergistically in combination with other weak activating factors. Mol Cell Biol (1990) 2.00
A beta-cell-specific protein binds to the two major regulatory sequences of the insulin gene enhancer. Proc Natl Acad Sci U S A (1988) 2.00
Amino-terminal domain of NF1 binds to DNA as a dimer and activates adenovirus DNA replication. EMBO J (1990) 1.95
Functional distinctions between yeast TATA elements. Mol Cell Biol (1989) 1.94
Common factor 1 is a transcriptional activator which binds in the c-myc promoter, the skeletal alpha-actin promoter, and the immunoglobulin heavy-chain enhancer. Mol Cell Biol (1991) 1.93
Purification and analysis of RNA polymerase II transcription factors by using wheat germ agglutinin affinity chromatography. Proc Natl Acad Sci U S A (1989) 1.90
Transcriptional initiation is controlled by upstream GC-box interactions in a TATAA-less promoter. Mol Cell Biol (1990) 1.90
Identification of basal and cyclic AMP regulatory elements in the promoter of the phosphoenolpyruvate carboxykinase gene. Mol Cell Biol (1988) 1.89
The DNA binding domain (POU domain) of transcription factor oct-1 suffices for stimulation of DNA replication. EMBO J (1990) 1.88
Properties of a CCAAT box-binding protein. Nucleic Acids Res (1987) 1.85
Identification of multiple proteins that interact with functional regions of the human cardiac alpha-actin promoter. Mol Cell Biol (1989) 1.82
The -117 mutation in Greek HPFH affects the binding of three nuclear factors to the CCAAT region of the gamma-globin gene. EMBO J (1988) 1.81
A variant nuclear protein in dedifferentiated hepatoma cells binds to the same functional sequences in the beta fibrinogen gene promoter as HNF-1. EMBO J (1988) 1.79
Cellular factors that interact with the hepatitis B virus enhancer. Mol Cell Biol (1989) 1.78
Multiple basal elements of a human hsp70 promoter function differently in human and rodent cell lines. Mol Cell Biol (1987) 1.77
Promoter and enhancer elements containing a conserved sequence motif are recognized by nuclear factor III, a protein stimulating adenovirus DNA replication. EMBO J (1987) 1.74
Tissue-specific transcription of the mouse alpha-fetoprotein gene promoter is dependent on HNF-1. Mol Cell Biol (1989) 1.74
A retinoic acid response element is present in the mouse cellular retinol binding protein I (mCRBPI) promoter. EMBO J (1991) 1.74
Mutagenesis of the rat insulin II 5'-flanking region defines sequences important for expression in HIT cells. Mol Cell Biol (1989) 1.72
Transcription factors NFI and NFIII/oct-1 function independently, employing different mechanisms to enhance adenovirus DNA replication. J Virol (1990) 1.72
The BCMA gene, preferentially expressed during B lymphoid maturation, is bidirectionally transcribed. Nucleic Acids Res (1994) 1.72
RNA polymerase II transcription termination is mediated specifically by protein binding to a CCAAT box sequence. Mol Cell Biol (1989) 1.67
Constitutive synthesis of activator protein 1 transcription factor after viral transformation of mouse fibroblasts. Proc Natl Acad Sci U S A (1988) 1.67
The gene for a novel human lamin maps at a highly transcribed locus of chromosome 19 which replicates at the onset of S-phase. Mol Cell Biol (1992) 1.66
Cell-type specific activity of two glucocorticoid responsive units of rat tyrosine aminotransferase gene is associated with multiple binding sites for C/EBP and a novel liver-specific nuclear factor. Nucleic Acids Res (1991) 1.66
Nuclear proteins that bind the human gamma-globin gene promoter: alterations in binding produced by point mutations associated with hereditary persistence of fetal hemoglobin. Mol Cell Biol (1988) 1.63
Cooperative activation of transcription by bovine papillomavirus type 1 E2 can occur over a large distance. Mol Cell Biol (1990) 1.63
Promoter upstream elements of the chicken cardiac myosin light-chain 2-A gene interact with trans-acting regulatory factors for muscle-specific transcription. Mol Cell Biol (1989) 1.63
Individual protein-binding domains of the insulin gene enhancer positively activate beta-cell-specific transcription. Mol Cell Biol (1989) 1.61
Association of herpes simplex virus regulatory protein ICP4 with sequences spanning the ICP4 gene transcription initiation site. Nucleic Acids Res (1988) 1.60
DNA replication origin and transcriptional enhancer in c-myc gene share the c-myc protein binding sequences. EMBO J (1989) 1.60
Role of multifunctional autonomously replicating sequence binding factor 1 in the initiation of DNA replication and transcriptional control in Saccharomyces cerevisiae. Mol Cell Biol (1992) 1.59
Positive and negative regulatory elements in the mouse albumin enhancer. Proc Natl Acad Sci U S A (1989) 1.58
The ABF1 factor is the transcriptional activator of the L2 ribosomal protein genes in Saccharomyces cerevisiae. Mol Cell Biol (1990) 1.56
A tissue-specific nuclear factor binds to multiple sites in the human insulin-gene enhancer. Biochem J (1989) 1.55
A protein factor binding to an octamer motif in the gamma-globin promoter disappears upon induction of differentiation and hemoglobin synthesis in K562 cells. Nucleic Acids Res (1987) 1.54
Lysozyme gene activity in chicken macrophages is controlled by positive and negative regulatory elements. Nucleic Acids Res (1987) 1.54
Mithramycin blocks protein binding and function of the SV40 early promoter. J Clin Invest (1989) 1.53
Identification of a novel constitutive enhancer element and an associated binding protein: implications for human papillomavirus type 11 enhancer regulation. J Virol (1989) 1.52
Recognition of the adenovirus type 2 origin of DNA replication by the virally encoded DNA polymerase and preterminal proteins. EMBO J (1992) 1.52
A combination of closely associated positive and negative cis-acting promoter elements regulates transcription of the skeletal alpha-actin gene. Mol Cell Biol (1990) 1.52
Negative regulation of the human epsilon-globin gene by transcriptional interference: role of an Alu repetitive element. Mol Cell Biol (1990) 1.51
Clusters of nuclear factor I binding sites identify enhancers of several papillomaviruses but alone are not sufficient for enhancer function. Nucleic Acids Res (1989) 1.50
rar mutations which increase artificial chromosome stability in Saccharomyces cerevisiae identify transcription and recombination proteins. Nucleic Acids Res (1991) 1.50
Recognition mechanisms in the synthesis of animal virus DNA. Biochem J (1989) 1.49
Nuclear factor I enhances adenovirus DNA replication by increasing the stability of a preinitiation complex. EMBO J (1992) 1.49
Chicken liver TGGCA protein purified by preparative mobility shift electrophoresis (PMSE) shows a 36.8 to 29.8 kd microheterogeneity. Nucleic Acids Res (1987) 1.48
A quantitative analysis of nuclear factor I/DNA interactions. Nucleic Acids Res (1988) 1.46
DNA sequences involved in transcriptional regulation of the mouse beta-globin promoter in murine erythroleukemia cells. Mol Cell Biol (1988) 1.45
Cell-cycle-specific interaction of nuclear DNA-binding proteins with a CCAAT sequence from the human thymidine kinase gene. Proc Natl Acad Sci U S A (1987) 1.45
Cloning of the human keratin 18 gene and its expression in nonepithelial mouse cells. Mol Cell Biol (1988) 1.43
A cDNA for a human cyclic AMP response element-binding protein which is distinct from CREB and expressed preferentially in brain. Mol Cell Biol (1990) 1.43
Discrimination among potential activators of the beta-globin CACCC element by correlation of binding and transcriptional properties. Mol Cell Biol (1993) 1.43
Upstream regulatory regions required to stabilize binding to the TATA sequence in an adenovirus early promoter. Nucleic Acids Res (1987) 1.43
Analysis of the transcript of the herpes simplex virus DNA polymerase gene provides evidence that polymerase expression is inefficient at the level of translation. J Virol (1988) 1.43
Site-specific DNA binding of nuclear factor I: effect of the spacer region. Nucleic Acids Res (1987) 1.41
Binding of multiple factors to the MMTV promoter in crude and fractionated nuclear extracts. Nucleic Acids Res (1988) 1.41
A mammary cell-specific enhancer in mouse mammary tumor virus DNA is composed of multiple regulatory elements including binding sites for CTF/NFI and a novel transcription factor, mammary cell-activating factor. Mol Cell Biol (1992) 1.40
A regulatory potential of the Xist gene promoter in vole M. rossiaemeridionalis. PLoS One (2012) 1.40
The nuclear protooncogenes c-jun and c-fos as regulators of DNA replication. Proc Natl Acad Sci U S A (1991) 1.40
Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science (1989) 25.68
The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter. Cell (1983) 15.09
Affinity purification of sequence-specific DNA binding proteins. Proc Natl Acad Sci U S A (1986) 14.92
Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Cell (1987) 14.62
Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins. Nature (1985) 14.41
Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell (1988) 12.68
Purification and biochemical characterization of the promoter-specific transcription factor, Sp1. Science (1986) 12.58
Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain. Cell (1987) 12.30
A restriction enzyme from Hemophilus influenzae. II. J Mol Biol (1970) 11.54
Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro. Cell (1985) 11.03
The binding site on SV40 DNA for a T antigen-related protein. Cell (1978) 10.58
Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1. Science (1987) 10.25
Regulation of simian virus 40 early transcription in vitro by a purified tumor antigen. Proc Natl Acad Sci U S A (1980) 10.22
A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA. Cell (1998) 10.14
Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II. Cell (1983) 8.85
The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain. Cell (1989) 8.60
Mechanism of transcriptional activation by Sp1: evidence for coactivators. Cell (1990) 8.18
Activation of the AIDS retrovirus promoter by the cellular transcription factor, Sp1. Science (1986) 8.01
Structure and function of a human TAFII250 double bromodomain module. Science (2000) 8.00
Transcriptional selectivity of viral genes in mammalian cells. Cell (1986) 7.95
Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins. Nature (1990) 7.91
Simian virus 40 DNA replication in vitro. Proc Natl Acad Sci U S A (1984) 7.76
Positive and negative regulation of transcription in vitro: enhancer-binding protein AP-2 is inhibited by SV40 T antigen. Cell (1987) 7.51
Construction and analysis of simian virus 40 origins defective in tumor antigen binding and DNA replication. Proc Natl Acad Sci U S A (1980) 7.04
Multiple specific contacts between a mammalian transcription factor and its cognate promoters. Nature (1985) 6.77
Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40. Nature (1987) 6.76
Structure of replicating simian virus 40 deoxyribonucleic acid molecules. J Virol (1971) 6.74
A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs. Nature (1988) 6.54
Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers. Science (1989) 6.51
Animal virus DNA replication. Annu Rev Biochem (1989) 6.41
Fos-associated protein p39 is the product of the jun proto-oncogene. Science (1988) 6.34
Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation. Cell (1991) 6.04
What's up and down with histone deacetylation and transcription? Cell (1997) 5.99
Adenovirus DNA replication in vitro. Proc Natl Acad Sci U S A (1979) 5.94
Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators. Cell (1993) 5.91
Orchestrated response: a symphony of transcription factors for gene control. Genes Dev (2000) 5.86
Going the distance: a current view of enhancer action. Science (1998) 5.83
O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation. Cell (1988) 5.82
Purification of nuclear factor I by DNA recognition site affinity chromatography. J Biol Chem (1986) 5.79
Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes. Genes Dev (1989) 5.59
The RCAF complex mediates chromatin assembly during DNA replication and repair. Nature (1999) 5.27
ACF, an ISWI-containing and ATP-utilizing chromatin assembly and remodeling factor. Cell (1997) 5.22
Topography of simian virus 40 A protein-DNA complexes: arrangement of pentanucleotide interaction sites at the origin of replication. J Virol (1983) 5.00
Bidirectional SV40 transcription mediated by tandem Sp1 binding interactions. Science (1985) 5.00
Integrated simian virus 40 sequences in transformed cell DNA: analysis using restriction endonucleases. Proc Natl Acad Sci U S A (1976) 4.92
Transcription factors that activate the Ultrabithorax promoter in developmentally staged extracts. Cell (1988) 4.87
Functional domains and upstream activation properties of cloned human TATA binding protein. Science (1990) 4.67
SV40 gene expression is modulated by the cooperative binding of T antigen to DNA. Cell (1981) 4.64
Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB. Cell (1993) 4.57
Enhancer-promoter specificity mediated by DPE or TATA core promoter motifs. Genes Dev (2001) 4.54
Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism. Genes Dev (1991) 4.54
Protein-DNA interactions at the origin of simian virus 40 DNA replication. Cold Spring Harb Symp Quant Biol (1979) 4.51
Synergistic activation by the glutamine-rich domains of human transcription factor Sp1. Cell (1989) 4.49
The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein. Genes Dev (1998) 4.38
Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation. Nature (1993) 4.38
The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway. Cell (1994) 4.30
A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation. Proc Natl Acad Sci U S A (1994) 4.27
The downstream core promoter element, DPE, is conserved from Drosophila to humans and is recognized by TAFII60 of Drosophila. Genes Dev (1997) 4.25
A thymus-specific member of the HMG protein family regulates the human T cell receptor C alpha enhancer. Genes Dev (1991) 4.25
Phosphorylation of the transcription factor PHO4 by a cyclin-CDK complex, PHO80-PHO85. Science (1994) 4.24
Transcription from a TATA-less promoter requires a multisubunit TFIID complex. Genes Dev (1991) 4.23
Initiation of simian virus 40 DNA replication in vitro: large-tumor-antigen- and origin-dependent unwinding of the template. Proc Natl Acad Sci U S A (1987) 4.23
Adenovirus DNA replication in vitro: characterization of a protein covalently linked to nascent DNA strands. Proc Natl Acad Sci U S A (1980) 4.20
Functional cooperativity between transcription factors UBF1 and SL1 mediates human ribosomal RNA synthesis. Science (1988) 4.17
Sequence-specific antirepression of histone H1-mediated inhibition of basal RNA polymerase II transcription. Science (1991) 4.12
The TATA-binding protein and associated factors are integral components of the RNA polymerase I transcription factor, SL1. Cell (1992) 4.11
The International Intravitreal Bevacizumab Safety Survey: using the internet to assess drug safety worldwide. Br J Ophthalmol (2006) 4.09
Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators. Cell (1994) 4.06
GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase. Cell (1990) 4.04
Sp1 binds to promoter sequences and activates herpes simplex virus 'immediate-early' gene transcription in vitro. Nature (1985) 3.99
Transcriptional coactivator complexes. Annu Rev Biochem (2001) 3.97
ACF consists of two subunits, Acf1 and ISWI, that function cooperatively in the ATP-dependent catalysis of chromatin assembly. Genes Dev (1999) 3.85
Simian virus 40 DNA replication in vitro: specificity of initiation and evidence for bidirectional replication. Mol Cell Biol (1985) 3.84
Enzymatic activities associated with a purified simian virus 40 T antigen-related protein. Proc Natl Acad Sci U S A (1979) 3.82
Use of nondefective adenovirus-simian virus 40 hybrids for mapping the simian virus 40 genome. J Virol (1973) 3.81
DNA template and activator-coactivator requirements for transcriptional synergism by Drosophila bicoid. Science (1995) 3.79
Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex. Genes Dev (1991) 3.77
p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60. Science (1995) 3.74
Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements. Genes Dev (1988) 3.72
Multiple tandemly repeated binding sites for cellular nuclear factor 1 that surround the major immediate-early promoters of simian and human cytomegalovirus. J Virol (1987) 3.68
Transcription factors IIE and IIH and ATP hydrolysis direct promoter clearance by RNA polymerase II. Cell (1994) 3.61
TAFs mediate transcriptional activation and promoter selectivity. Trends Biochem Sci (1996) 3.59
Role of nucleosomal cores and histone H1 in regulation of transcription by RNA polymerase II. Science (1991) 3.55
Drosophila TFIID binds to a conserved downstream basal promoter element that is present in many TATA-box-deficient promoters. Genes Dev (1996) 3.55
Interaction of DNA polymerase alpha-primase with cellular replication protein A and SV40 T antigen. EMBO J (1992) 3.53
Analysis of the DNA-binding and activation properties of the human transcription factor AP-2. Genes Dev (1991) 3.50
Direct interaction between Sp1 and the BPV enhancer E2 protein mediates synergistic activation of transcription. Cell (1991) 3.46
Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis. Genes Dev (1991) 3.46
Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity. Genes Dev (1990) 3.44
The genome of simian virus 40. Adv Virus Res (1977) 3.42