R Callahan

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Notch signaling is essential for vascular morphogenesis in mice. Genes Dev 2000 6.88
2 Loss of heterozygosity on chromosome 7q and aggressive primary breast cancer. Lancet 1992 3.11
3 Isolation from the asian mouse Mus caroli of an endogenous type C virus related to infectious primate type C viruses. Proc Natl Acad Sci U S A 1975 2.71
4 Infection and labor. V. Prevalence, microbiology, and clinical significance of intraamniotic infection in women with preterm labor and intact membranes. Am J Obstet Gynecol 1989 2.69
5 Detection of baboon type C viral sequences in various primate tissues by molecular hybridization. J Virol 1974 2.69
6 Genetic alteration of the c-myc protooncogene (MYC) in human primary breast carcinomas. Proc Natl Acad Sci U S A 1986 2.66
7 Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands. Genes Dev 1992 2.59
8 Nucleic acid homology of murine type-C viral genes. J Virol 1974 2.51
9 Mammary tumorigenesis in feral mice: identification of a new int locus in mouse mammary tumor virus (Czech II)-induced mammary tumors. J Virol 1987 2.51
10 Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells. J Virol 1992 2.29
11 Major pol gene progenitors in the evolution of oncoviruses. Science 1984 2.28
12 Reduction to homozygosity of genes on chromosome 11 in human breast neoplasia. Science 1987 2.17
13 Presence of two members of c-erbA receptor gene family (c-erbA beta and c-erbA2) in smallest region of somatic homozygosity on chromosome 3p21-p25 in human breast carcinoma. J Natl Cancer Inst 1989 2.09
14 Two distinct endogenous type C viruses isolated from the asian rodent Mus cervicolor: conservation of virogene sequences in related rodent species. J Virol 1977 1.98
15 Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis. Cancer Res 1996 1.90
16 A new class of endogenous human retroviral genomes. Science 1985 1.89
17 Nucleic acid homology of murine xenotropic type C viruses. J Virol 1975 1.82
18 The mouse mammary tumor associated gene INT3 is a unique member of the NOTCH gene family (NOTCH4). Oncogene 1997 1.81
19 Int-6, a highly conserved, widely expressed gene, is mutated by mouse mammary tumor virus in mammary preneoplasia. J Virol 1995 1.79
20 Detection and cloning of human DNA sequences related to the mouse mammary tumor virus genome. Proc Natl Acad Sci U S A 1982 1.74
21 Constitutive expression of a truncated INT3 gene in mouse mammary epithelium impairs differentiation and functional development. Cell Growth Differ 1995 1.62
22 Novel class of mouse mammary tumor virus-related DNA sequences found in all species of Mus, including mice lacking the virus proviral genome. Proc Natl Acad Sci U S A 1982 1.58
23 High frequency of rare alleles of the human c-Ha-ras-1 proto-oncogene in breast cancer patients. J Natl Cancer Inst 1986 1.52
24 Loss of a c-H-ras-1 allele and aggressive human primary breast carcinomas. Cancer Res 1986 1.52
25 Endogenous primate and feline type C viruses. Cold Spring Harb Symp Quant Biol 1975 1.51
26 Somatic allelic deletion of nm23 in human cancer. Cancer Res 1991 1.50
27 A new class of genetically transmitted retravirus isolated from Mus cervicolor. Proc Natl Acad Sci U S A 1976 1.46
28 A new common integration region (int-3) for mouse mammary tumor virus on mouse chromosome 17. J Virol 1987 1.45
29 Frequent alteration of the DF3 tumor-associated antigen gene in primary human breast carcinomas. Cancer Res 1989 1.41
30 Amplification of the int-2 gene in primary human breast tumors. Oncogene Res 1988 1.40
31 In vitro synthesis of adenovirus core proteins. J Virol 1974 1.35
32 Cell-free synthesis of adenovirus coat proteins. J Biol Chem 1974 1.34
33 Two distinct regions involved in 1p deletion in human primary breast cancer. Cancer Res 1993 1.33
34 Ancestry of a human endogenous retrovirus family. J Virol 1989 1.26
35 Reduced expression of INT-6/eIF3-p48 in human tumors. Int J Oncol 2001 1.26
36 Amniotic fluid glucose concentration: a rapid and simple method for the detection of intraamniotic infection in preterm labor. Am J Obstet Gynecol 1990 1.26
37 Male and female mouse DNAs can be discriminated using retroviral probes. Nature 1982 1.24
38 Identification of a novel NOTCH-4/INT-3 RNA species encoding an activated gene product in certain human tumor cell lines. Oncogene 2000 1.23
39 A new class of murine retroviruses: immunological and biochemical comparison of novel isolates from Mus cervicolor and Mus caroli. Virology 1977 1.23
40 Relationship between airway narrowing, patchy ventilation and lung mechanics in asthmatics. Eur Respir J 2007 1.20
41 Evidence for the transforming activity of a truncated Int6 gene, in vitro. Oncogene 2001 1.20
42 Genetic relationship between the Mus cervicolor M432 retrovirus and the Mus Musculus intracisternal type A particle. J Virol 1981 1.19
43 An endogenous mouse mammary tumor virus genome common in inbred mouse strains is located on chromosome 6. J Virol 1986 1.19
44 Immunological relationship between the structural proteins of intracisternal A-particles of Mus musculus and the M432 retrovirus of Mus cervicolor. J Virol 1980 1.18
45 Loss of heterozygosity on chromosomes 17 and 18 in breast carcinoma: two additional regions identified. Proc Natl Acad Sci U S A 1990 1.15
46 Mutations in the p53 gene in primary human breast cancers. Cancer Res 1991 1.15
47 The chromosome location of the human homolog of the mouse mammary tumor-associated gene INT6 and its status in human breast carcinomas. Genomics 1997 1.15
48 Long-term in vivo expression of genes introduced by retrovirus-mediated transfer into mammary epithelial cells. J Virol 1991 1.15
49 Two genetically transmitted BALB/c mouse mammary tumor virus genomes located on chromosomes 12 and 16. J Virol 1984 1.13
50 Regulatory mutants of the tryptophan operon of Salmonella typhimurium. Genetics 1970 1.13
51 Multiple regions of chromosome 6q affected by loss of heterozygosity in primary human breast carcinomas. Br J Cancer 1996 1.12
52 Analysis of adenovirus type 2 gene functions by cell-free translation of viral messenger RNA. Cold Spring Harb Symp Quant Biol 1975 1.11
53 Lack of evidence for the prognostic significance of c-erbB-2 amplification in human breast carcinoma. Oncogene Res 1988 1.10
54 In situ c-myc expression and genomic status of the c-myc locus in infiltrating ductal carcinomas of the breast. Cancer Res 1988 1.10
55 Meconium-stained amniotic fluid: a risk factor for microbial invasion of the amniotic cavity. Am J Obstet Gynecol 1991 1.10
56 p53 mutations and histological type of invasive breast carcinoma. Cancer Res 1993 1.06
57 p53 alterations in non-small cell lung cancers correlate with metastatic involvement of hilar and mediastinal lymph nodes. Cancer Res 1993 1.05
58 The amplification unit on chromosome 11q13 in aggressive primary human breast tumors entails the bcl-1, int-2 and hst loci. Oncogene 1989 1.05
59 Loss of heterozygosity on chromosome 17p13 in breast carcinomas identifies tumors with high proliferation index. Am J Pathol 1992 1.05
60 Bovine leukemia virus genes in the DNA of leukemic cattle. Science 1976 1.04
61 Redistribution of regional and organ blood volume and effect on cardiac function in relation to upright exercise intensity in healthy human subjects. Circulation 1990 1.03
62 Rbpj conditional knockout reveals distinct functions of Notch4/Int3 in mammary gland development and tumorigenesis. Oncogene 2008 1.03
63 Host genetic background effect on the frequency of mouse mammary tumor virus-induced rearrangements of the int-1 and int-2 loci in mouse mammary tumors. J Virol 1991 1.01
64 Chromosomal localization of the met proto-oncogene in the mouse and cat genome. Genomics 1987 1.00
65 ras gene alterations and enhanced levels of ras p21 expression in a spectrum of benign and malignant human mammary tissues. Lab Invest 1986 1.00
66 Amplification of the proto-oncogenes int-2, c-erb B-2 and c-myc in human breast cancer. Clin Chim Acta 1989 0.99
67 Mammary tumorigenesis in feral Mus cervicolor popaeus. J Virol 1986 0.96
68 Identification of three regions on chromosome 17q in primary human breast carcinomas which are frequently deleted. Cancer Res 1993 0.95
69 Genetic mapping of Prm-1, Igl-1, Smst, Mtv-6, Sod-1, and Ets-2 and localization of the Down syndrome region on mouse chromosome 16. Cytogenet Cell Genet 1987 0.94
70 p53 mutations, another breast cancer prognostic factor. J Natl Cancer Inst 1992 0.93
71 Isolation of an endogenous type C virus related to the infectious primate type C viruses from the Asian rodent Vandeleuria oleracea. J Virol 1979 0.93
72 Growth suppression of normal mammary epithelial cells by wild-type p53. Oncogene 1994 0.92
73 Transformation of an established mouse mammary epithelial cell line following transfection with a human transforming growth factor alpha cDNA. Mol Carcinog 1989 0.91
74 NME1 protein expression and loss of heterozygosity mutations in primary human breast tumors. J Natl Cancer Inst 1994 0.91
75 Chromosomal locations of members of a family of novel endogenous human retroviral genomes. J Virol 1986 0.91
76 Infection and labor. VI. Prevalence, microbiology, and clinical significance of intraamniotic infection in twin gestations with preterm labor. Am J Obstet Gynecol 1990 0.90
77 Evidence for involvement of BRCA1 in sporadic breast carcinomas. Cancer Res 1994 0.90
78 Tryptophan operon: structural gene mutation creating a "promoter" and leading to 5-methyltryptophan dependence. Science 1970 0.89
79 Lipoprotein-associated oncornavirus-inactivating factor in the genus Mus: effects on murine leukemia viruses of laboratory and exotic mice. Cancer Res 1987 0.87
80 Enhanced expression of c-Ha-ras p21 in human stomach adenocarcinomas defined by immunoassays using monoclonal antibodies and in situ hybridization. Cancer Res 1987 0.87
81 Prognostic significance of loss of heterozygosity at loci on chromosome 17p13.3-ter in sporadic breast cancer is evidence for a putative tumour suppressor gene. Br J Cancer 1999 0.87
82 The mouse biliary glycoprotein gene (Bgp): partial nucleotide sequence, expression, and chromosomal assignment. Genomics 1991 0.87
83 Characterization of the INT6 mammary tumor gene product. DNA Cell Biol 1997 0.87
84 Evidence for the order promoter-operator-first structural gene in the tryptophan operon of Salmonella. J Mol Biol 1970 0.87
85 Endogenous MMTV proviral genomes in feral Mus musculus domesticus. Curr Top Microbiol Immunol 1986 0.86
86 Characterization of a new virus from Mus cervicolor immunologically related to the mouse mammary tumor virus. J Natl Cancer Inst 1978 0.86
87 Evidence for a second tumor suppressor gene on 17p linked to high S-phase index in primary human breast carcinomas. Cancer Genet Cytogenet 1994 0.86
88 Kit and PDGFR-alpha activities are necessary for Notch4/Int3-induced tumorigenesis. Oncogene 2006 0.86
89 The chromosomal location of the mouse mammary tumor gene Int6 and related pseudogenes in the mouse genome. Genomics 1995 0.86
90 In primary human breast carcinomas mutations in exons 5 and 6 of the p53 gene are associated with a high S-phase index. Int J Cancer 1993 0.85
91 mRNA expression of transforming growth factor alpha in human breast carcinomas and its activity in effusions of breast cancer patients. J Natl Cancer Inst 1989 0.85
92 Detection of amphiregulin and Cripto-1 in mammary tumors from transgenic mice. Mol Carcinog 1996 0.85
93 A novel non-mouse mammary tumor virus activation of the Int-3 gene in a spontaneous mouse mammary tumor. J Virol 1995 0.84
94 Differentiation of regional perfusion and fatty acid uptake in zones of myocardial injury. Nucl Med Commun 1991 0.84
95 Induction of transforming growth factor alpha expression in mouse mammary epithelial cells after transformation with a point-mutated c-Ha-ras protooncogene. Mol Endocrinol 1988 0.83
96 Expression of int-2 mRNA in human tumors amplified at the int-2 locus. Oncogene 1989 0.83
97 Fainting: a review of its mechanisms and a study in blood donors. Medicine (Baltimore) 1967 0.83
98 Chimeric B72.3 mouse/human (IgG1) antibody directs the lysis of tumor cells by lymphokine-activated killer cells. Cancer Immunol Immunother 1990 0.82
99 Mammary tumorigenesis in feral species of the genus Mus. Curr Top Microbiol Immunol 1986 0.82
100 Characterization of the Drosophila ortholog of mouse eIF-3p48/INT-6. Gene 1999 0.81
101 Candidate target genes for loss of heterozygosity on human chromosome 17q21. Br J Cancer 2004 0.81
102 Translational initiation: defects arising in Escherichia coli infected with phage T7, , and Q . Arch Biochem Biophys 1972 0.80
103 Transforming growth factor-alpha messenger RNA localization in the developing adult rat and human mammary gland by in situ hybridization. Dev Biol 1990 0.80
104 Biochemical characterization of endogenous type C virus information in differentiated and undifferentiated murine teratocarcinoma-derived cell lines. J Virol 1980 0.79
105 Detection of loss of heterozygosity in tumor DNA samples by PCR. Biotechniques 1991 0.79
106 Imaging of Pneumocystis carinii pneumonia with 111In-labelled non-specific polyclonal IgG: an experimental study in rats. Nucl Med Commun 1991 0.79
107 [Demonstration of two regions involved in chromosome 1p deletion in breast tumors]. Bull Cancer 1994 0.79
108 Isovolemic hemodilution in experimental focal cerebral ischemia. Part 1: Effects on hemodynamics, hemorheology, and intracranial pressure. J Neurosurg 1988 0.79
109 Loss of heterozygosity of the L-myc oncogene in human breast tumors. Hum Genet 1990 0.79
110 Detection of novel murine mammary tumor viruses by interspecies immunoassays. J Natl Cancer Inst 1980 0.79
111 Interspecies radioimmunoassay for the major internal protein of mammary tumor viruses. Virology 1980 0.79
112 Specific and nonspecific imaging of localized Fisher immunotype 1 Pseudomonas aeruginosa infection with radiolabeled monoclonal antibody. J Nucl Med 1988 0.79
113 The int-2 gene product acts as a growth factor and substitutes for basic fibroblast growth factor in promoting the differentiation of a normal mouse mammary epithelial cell line. Cell Growth Differ 1992 0.78
114 Detection of DNA mutations in acid formalin-fixed paraffin-embedded archival tumor specimens by polymerase chain reaction-single strand conformation polymorphism analysis. Cancer Detect Prev 1995 0.78
115 In situ detection of c-myc mRNA in adenocarcinomas, adenomas, and mucosa of human colon. J Histochem Cytochem 1989 0.78
116 Genetic transmission of retroviral genes and cellular oncogenes. Proc R Soc Lond B Biol Sci 1980 0.77
117 A mutation to 5-methyltryptophan dependence in the tryptophan (trp) operon of Salmonella typhimurium. II. Studies of 5-methyltryptophan-dependent mutants and their revertants. Mol Gen Genet 1978 0.76
118 Genetic variability of proto-oncogenes for breast cancer risk and prognosis. Biochimie 1988 0.76
119 Infectious primate type C virus group: evidence for an origin from an endogenous virus of the rodent, Mus caroli. Bibl Haematol 1975 0.76
120 p53 mutations and histologic type of invasive breast carcinoma. A polymerase chain reaction-single-strand conformation polymorphism and immunohistochemical analysis. Ann N Y Acad Sci 1993 0.75
121 Direct measurement of tubulin and bulk message distributions on polysomes of growing, starved and deciliated Tetrahymena using RNA gel blots of sucrose gradients containing acrylamide. Nucleic Acids Res 1988 0.75
122 A locus on chromosome 17p13.3, associated with a high S-phase index is distinct from the p53 gene in breast cancer. Ann N Y Acad Sci 1993 0.75
123 Growth suppression of normal mammary epithelial cells by wild-type p53. Ann N Y Acad Sci 1993 0.75
124 Heterogeneity of genetic alterations in primary human breast tumors. Cancer Treat Res 1988 0.75
125 Noninvasive diagnosis of Pneumocystis carinii in the rat using radiolabeled, nonspecific, human polyclonal immunoglobulin. J Protozool 1989 0.75
126 Effect of heta-starch colloidal solutions on reticuloendothelial phagocytic system (RES) function in burned and infected rats. Burns 1992 0.75
127 Effect of a bedtime snack on sleep. J Am Diet Assoc 1966 0.75
128 T-cell receptor b-V repertoire expression in the absence of an endogenous mouse mammary tumor provirus. Immunogenetics 1993 0.75
129 In vitro initiation of coliphage T7 mRNA. Arch Biochem Biophys 1972 0.75
130 The genetic stability of endogenous type B and C retroviruses in BALB/c sublines. Curr Top Microbiol Immunol 1985 0.75
131 Diffusing capacity is not measurably affected by routine lung perfusion scanning. J Nucl Med 1988 0.75