Published in Lancet on April 25, 1992
Translocator protein 18 kDa (TSPO): molecular sensor of brain injury and repair. Pharmacol Ther (2008) 2.47
Two binding sites for [3H]PBR28 in human brain: implications for TSPO PET imaging of neuroinflammation. J Cereb Blood Flow Metab (2010) 1.85
[11C]-DPA-713 and [18F]-DPA-714 as new PET tracers for TSPO: a comparison with [11C]-(R)-PK11195 in a rat model of herpes encephalitis. Mol Imaging Biol (2009) 1.43
The positron emission tomography ligand DAA1106 binds with high affinity to activated microglia in human neurological disorders. J Neuropathol Exp Neurol (2008) 1.12
The high affinity peripheral benzodiazepine receptor ligand DAA1106 binds specifically to microglia in a rat model of traumatic brain injury: implications for PET imaging. Exp Neurol (2007) 1.12
Imaging the head: functional imaging. J Neurol Neurosurg Psychiatry (1995) 0.99
Transient focal ischemia results in persistent and widespread neuroinflammation and loss of glutamate NMDA receptors. Neuroimage (2010) 0.99
Human cellular inflammation in the pathology of acute cerebral ischaemia. J Neurol Neurosurg Psychiatry (2003) 0.97
Positron emission tomography imaging of neuroinflammation. J Child Neurol (2009) 0.97
The methodology of TSPO imaging with positron emission tomography. Biochem Soc Trans (2015) 0.96
Adaptive immune regulation of glial homeostasis as an immunization strategy for neurodegenerative diseases. J Neurochem (2010) 0.89
The development, past achievements, and future directions of brain PET. J Cereb Blood Flow Metab (2012) 0.84
Dynamics of neuroinflammation in the macrosphere model of arterio-arterial embolic focal ischemia: an approximation to human stroke patterns. Exp Transl Stroke Med (2010) 0.81
Imaging Neuroinflammation - from Bench to Bedside. J Clin Cell Immunol (2014) 0.77
Emerging ideas: can erythromycin reduce the risk of aseptic loosening? Clin Orthop Relat Res (2011) 0.75
Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest (2001) 23.21
A voxel-based morphometric study of ageing in 465 normal adult human brains. Neuroimage (2001) 19.86
Analysis of fMRI time-series revisited. Neuroimage (1995) 17.70
Regulation of simian virus 40 early transcription in vitro by a purified tumor antigen. Proc Natl Acad Sci U S A (1980) 10.22
Movement-related effects in fMRI time-series. Magn Reson Med (1996) 8.87
Navigation-related structural change in the hippocampi of taxi drivers. Proc Natl Acad Sci U S A (2000) 8.17
Assessing the significance of focal activations using their spatial extent. Hum Brain Mapp (1994) 7.28
Trinucleotide repeat length instability and age of onset in Huntington's disease. Nat Genet (1993) 6.53
Functional connectivity: the principal-component analysis of large (PET) data sets. J Cereb Blood Flow Metab (1993) 6.20
The neural correlates of the verbal component of working memory. Nature (1993) 6.13
Silent ischemia as a central problem: regional brain activation compared in silent and painful myocardial ischemia. Ann Intern Med (1996) 6.11
A direct demonstration of functional specialization in human visual cortex. J Neurosci (1991) 5.71
Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012. Euro Surveill (2012) 4.96
Quantitative measurement of regional cerebral blood flow and oxygen metabolism in man using 15O and positron emission tomography: theory, procedure, and normal values. J Comput Assist Tomogr (1980) 4.94
Other minds in the brain: a functional imaging study of "theory of mind" in story comprehension. Cognition (1995) 4.92
Area V5 of the human brain: evidence from a combined study using positron emission tomography and magnetic resonance imaging. Cereb Cortex (1993) 4.79
Comparing functional (PET) images: the assessment of significant change. J Cereb Blood Flow Metab (1991) 4.69
Cerebral asymmetry and the effects of sex and handedness on brain structure: a voxel-based morphometric analysis of 465 normal adult human brains. Neuroimage (2001) 4.52
A voxel-based morphometry study of semantic dementia: relationship between temporal lobe atrophy and semantic memory. Ann Neurol (2000) 4.22
Knowing where and getting there: a human navigation network. Science (1998) 4.15
Functional anatomy of a common semantic system for words and pictures. Nature (1996) 4.14
Parametric imaging of ligand-receptor binding in PET using a simplified reference region model. Neuroimage (1997) 4.13
Brain activity during stimulus independent thought. Neuroreport (1996) 4.00
Treatment-induced cortical reorganization after stroke in humans. Stroke (2000) 3.83
The relationship between global and local changes in PET scans. J Cereb Blood Flow Metab (1990) 3.78
Abnormal monitoring of inner speech: a physiological basis for auditory hallucinations. Lancet (1995) 3.74
Cerebral blood flow, blood volume and oxygen utilization. Normal values and effect of age. Brain (1990) 3.54
In-vivo measurement of activated microglia in dementia. Lancet (2001) 3.51
Characterizing evoked hemodynamics with fMRI. Neuroimage (1995) 3.39
Willed action and the prefrontal cortex in man: a study with PET. Proc Biol Sci (1991) 3.33
Hypothalamic activation in cluster headache attacks. Lancet (1998) 3.32
Elevating clinical licensing examinations to professional testing standards. N Y State Dent J (1998) 3.20
Positron emission tomography for in-vivo measurement of regional blood flow, oxygen utilisation, and blood volume in patients with breast carcinoma. Lancet (1984) 3.05
The prefrontal cortex: response selection or maintenance within working memory? Science (2000) 2.91
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity. Brain (2000) 2.84
Characterizing dynamic brain responses with fMRI: a multivariate approach. Neuroimage (1995) 2.84
The Huntington's disease candidate region exhibits many different haplotypes. Nat Genet (1992) 2.84
The functional anatomy of motor recovery after stroke in humans: a study with positron emission tomography. Ann Neurol (1991) 2.84
Recalling routes around london: activation of the right hippocampus in taxi drivers. J Neurosci (1997) 2.79
Brain regions associated with acquisition and retrieval of verbal episodic memory. Nature (1994) 2.71
Motor sequence learning: a study with positron emission tomography. J Neurosci (1994) 2.71
The colour centre in the cerebral cortex of man. Nature (1989) 2.69
Analysis of temporal structure in sound by the human brain. Nat Neurosci (1998) 2.68
Cortical areas and the selection of movement: a study with positron emission tomography. Exp Brain Res (1991) 2.68
Functional localization of the system for visuospatial attention using positron emission tomography. Brain (1997) 2.67
Correlation between structural and functional changes in brain in an idiopathic headache syndrome. Nat Med (1999) 2.67
Comparison of methods for analysis of clinical [11C]raclopride studies. J Cereb Blood Flow Metab (1996) 2.66
The anatomy of melancholia--focal abnormalities of cerebral blood flow in major depression. Psychol Med (1992) 2.58
A voxel-based method for the statistical analysis of gray and white matter density applied to schizophrenia. Neuroimage (1995) 2.58
Differing patterns of striatal 18F-dopa uptake in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy. Ann Neurol (1990) 2.45
Central nervous pathways mediating angina pectoris. Lancet (1994) 2.38
The trouble with cognitive subtraction. Neuroimage (1996) 2.35
Investigations of the functional anatomy of attention using the Stroop test. Neuropsychologia (1993) 2.35
Time course of wallerian degeneration after ischaemic stroke revealed by diffusion tensor imaging. J Neurol Neurosurg Psychiatry (2005) 2.34
Functional reorganization of the brain in recovery from striatocapsular infarction in man. Ann Neurol (1992) 2.34
The role of the right hemisphere in the interpretation of figurative aspects of language. A positron emission tomography activation study. Brain (1994) 2.29
Anatomy of motor learning. I. Frontal cortex and attention to action. J Neurophysiol (1997) 2.29
A fronto-parietal network for rapid visual information processing: a PET study of sustained attention and working memory. Neuropsychologia (1996) 2.27
Mechanisms of placebo analgesia: rACC recruitment of a subcortical antinociceptive network. Pain (2005) 2.26
Where in the brain does visual attention select the forest and the trees? Nature (1996) 2.24
Patterns of cerebral blood flow in schizophrenia. Br J Psychiatry (1992) 2.21
White matter asymmetry in the human brain: a diffusion tensor MRI study. Cereb Cortex (2004) 2.19
Hearing and saying. The functional neuro-anatomy of auditory word processing. Brain (1996) 2.19
A PET study of word finding. Neuropsychologia (1991) 2.18
Noun and verb retrieval by normal subjects. Studies with PET. Brain (1996) 2.13
Motor cortex plasticity during constraint-induced movement therapy in stroke patients. Neurosci Lett (1998) 2.09
Demonstrating the implicit processing of visually presented words and pseudowords. Cereb Cortex (1996) 2.09
Functional topography: multidimensional scaling and functional connectivity in the brain. Cereb Cortex (1996) 2.08
Regional cerebral oxygen supply and utilization in dementia. A clinical and physiological study with oxygen-15 and positron tomography. Brain (1981) 2.08
Functional mapping of brain areas implicated in auditory--verbal memory function. Brain (1993) 2.08
Monitoring response to therapy in cancer using [18F]-2-fluoro-2-deoxy-D-glucose and positron emission tomography: an overview of different analytical methods. Eur J Nucl Med (2000) 2.06
Is developmental dyslexia a disconnection syndrome? Evidence from PET scanning. Brain (1996) 2.02
Variability in fMRI: an examination of intersession differences. Neuroimage (2000) 2.01
The mind's eye--precuneus activation in memory-related imagery. Neuroimage (1995) 2.00
Artifacts due to stimulus correlated motion in functional imaging of the brain. Magn Reson Med (1994) 1.99
Individual patterns of functional reorganization in the human cerebral cortex after capsular infarction. Ann Neurol (1993) 1.98
Multiple nonprimary motor areas in the human cortex. J Neurophysiol (1997) 1.97
Anatomy of motor learning. II. Subcortical structures and learning by trial and error. J Neurophysiol (1997) 1.97
A functional neuroanatomy of tics in Tourette syndrome. Arch Gen Psychiatry (2000) 1.94
Review: does measurement of regional cerebral blood flow reflect synaptic activity? Implications for PET and fMRI. Neuroimage (1995) 1.93
Functional anatomy of the mental representation of upper extremity movements in healthy subjects. J Neurophysiol (1995) 1.92
Relation between cerebral activity and force in the motor areas of the human brain. J Neurophysiol (1995) 1.91
Changes in relative biological effectiveness with depth of the Clatterbridge neutron therapy beam. Br J Radiol (1988) 1.91
The cortical localization of the lexicons. Positron emission tomography evidence. Brain (1992) 1.91
Conscious visual perception without V1. Brain (1993) 1.89
Motor cortex disinhibition of the unaffected hemisphere after acute stroke. Muscle Nerve (2000) 1.88
Impaired mesial frontal and putamen activation in Parkinson's disease: a positron emission tomography study. Ann Neurol (1992) 1.86
Painful stimuli evoke different stimulus-response functions in the amygdala, prefrontal, insula and somatosensory cortex: a single-trial fMRI study. Brain (2002) 1.84
Regional cerebral blood flow during volitional breathing in man. J Physiol (1991) 1.84
A review of differences between basal ganglia and cerebellar control of movements as revealed by functional imaging studies. Brain (1998) 1.83
Brainstem activation specific to migraine headache. Lancet (2001) 1.80
Neural basis of an inherited speech and language disorder. Proc Natl Acad Sci U S A (1998) 1.76
Acute stroke evaluated by time-to-peak mapping during initial and early follow-up perfusion CT studies. AJNR Am J Neuroradiol (2000) 1.74
Training-induced brain plasticity in aphasia. Brain (1999) 1.73