Published in J Exp Med on November 01, 1992
The biology of activin: recent advances in structure, regulation and function. J Endocrinol (2009) 1.64
Activin A is a critical component of the inflammatory response, and its binding protein, follistatin, reduces mortality in endotoxemia. Proc Natl Acad Sci U S A (2007) 1.62
Activin A programs the differentiation of human TFH cells. Nat Immunol (2016) 1.45
Expression of immunoreactive activin A protein in remodeling lesions associated with interstitial pulmonary fibrosis. Am J Pathol (1996) 0.97
cDNA array analysis of altered gene expression in human endothelial cells in response to Chlamydia pneumoniae infection. Infect Immun (2001) 0.94
The glycoprotein-hormones activin A and inhibin A interfere with dendritic cell maturation. Reprod Biol Endocrinol (2008) 0.85
Activin, neutrophils, and inflammation: just coincidence? Semin Immunopathol (2013) 0.85
Expression profiling of cardiovascular disease. Hum Genomics (2004) 0.84
Induced expression of the new cytokine, activin A, in human monocytes: inhibition by glucocorticoids and retinoic acid. Immunology (1996) 0.82
Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res (1984) 86.56
Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature (1984) 24.45
The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature (1988) 14.43
Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C. Biochemistry (1984) 10.83
Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA. Nucleic Acids Res (1984) 6.56
Novel method for studying mRNA phenotypes in single or small numbers of cells. J Cell Biochem (1989) 3.30
Differentiation in erythroleukemic cells and their somatic hybrids. Proc Natl Acad Sci U S A (1975) 3.05
Structure of two human ovarian inhibins. Biochem Biophys Res Commun (1986) 1.57
Purification and characterization of erythroid differentiation factor (EDF) isolated from human leukemia cell line THP-1. Biochem Biophys Res Commun (1987) 1.43
Gonadal and extragonadal expression of inhibin alpha, beta A, and beta B subunits in various tissues predicts diverse functions. Proc Natl Acad Sci U S A (1988) 1.40
Erythroid differentiation factor is encoded by the same mRNA as that of the inhibin beta A chain. Proc Natl Acad Sci U S A (1988) 1.28
Activin-like factor from a Xenopus laevis cell line responsible for mesoderm induction. Nature (1990) 1.25
Induction of human monocyte to macrophage maturation in vitro by 1,25-dihydroxyvitamin D3. Blood (1990) 1.17
Importance of FSH-releasing protein and inhibin in erythrodifferentiation. Nature (1988) 1.15
Selective and indirect modulation of human multipotential and erythroid hematopoietic progenitor cell proliferation by recombinant human activin and inhibin. Proc Natl Acad Sci U S A (1988) 1.11
Evidence for the participation of endogenous activin A/erythroid differentiation factor in the regulation of erythropoiesis. Proc Natl Acad Sci U S A (1992) 0.93
In vivo treatment with erythroid differentiation factor (EDF/activin A) increases erythroid precursors (CFU-E and BFU-E) in mice. Biochem Biophys Res Commun (1989) 0.90
Expression of activin A/erythroid differentiation factor in murine bone marrow stromal cells. Blood (1992) 0.84
Inducible gene expression of activin A/erythroid differentiation factor in HL-60 cells. Biochem Biophys Res Commun (1990) 0.79
Scoring of patellofemoral disorders. Arthroscopy (1993) 3.89
Mutations in an oocyte-derived growth factor gene (BMP15) cause increased ovulation rate and infertility in a dosage-sensitive manner. Nat Genet (2000) 3.05
Plasma insulin-like growth factor-I, insulin-like growth factor-binding proteins, and prostate cancer risk: a prospective study. J Natl Cancer Inst (2000) 2.34
Plasma level of soluble urokinase-type plasminogen activator receptor as a predictor of disease severity and case fatality in patients with bacteraemia: a prospective cohort study. J Intern Med (2011) 2.29
Presence of the IL-1RA allele 2 (IL1RN*2) is associated with enhanced IL-1beta production in vitro. Scand J Immunol (1998) 2.06
Risk of minor and major fetal malformations in diabetics with high haemoglobin A1c values in early pregnancy. Br Med J (Clin Res Ed) (1984) 1.77
When do social inequalities in C-reactive protein start? A life course perspective from conception to adulthood in the Cardiovascular Risk in Young Finns Study. Int J Epidemiol (2007) 1.74
The lumbar multifidus muscle five years after surgery for a lumbar intervertebral disc herniation. Spine (Phila Pa 1976) (1993) 1.73
Diagnosis of ectopic pregnancy by vaginal ultrasonography in combination with a discriminatory serum hCG level of 1000 IU/l (IRP) Br J Obstet Gynaecol (1990) 1.65
Radioimmunoassay of plasma renin activity. Clin Chem (1976) 1.62
Rapid measurement of urinary trypsinogen-2 as a screening test for acute pancreatitis. N Engl J Med (1997) 1.61
Genetic association between interleukin-10 promoter region polymorphisms and primary Sjögren's syndrome. Arthritis Rheum (2001) 1.59
Ovarian cancer antigen CA 125 levels in pelvic inflammatory disease and pregnancy. Cancer (1986) 1.55
Cytotoxic T-cell responses to H-Y: mapping of the Ir genes. J Exp Med (1978) 1.53
Normal early pregnancy: serum hCG levels and vaginal ultrasonography findings. Br J Obstet Gynaecol (1990) 1.53
Interleukin-10 generation in atopic children following oral Lactobacillus rhamnosus GG. Clin Exp Allergy (2000) 1.53
Measurement of the complex between prostate-specific antigen and alpha1-protease inhibitor in serum. Clin Chem (1999) 1.52
Polycystic ovaries and levels of gonadotrophins and androgens in recurrent miscarriage: prospective study in 50 women. Br J Obstet Gynaecol (1993) 1.51
Cytotoxic T-cell responses to H-Y: correlation with the rejection of syngeneic male skin grafts. J Exp Med (1978) 1.51
Serum tumour markers CA 15-3, TPA, TPS, hCGbeta and TATI in the monitoring of chemotherapy response in metastatic breast cancer. Scand J Clin Lab Invest (2001) 1.47
Quantification of prostate specific antigen mRNA levels in circulation after prostatic surgery and endocrine treatment by quantitative reverse transcription-polymerase chain reaction. Scand J Clin Lab Invest (2004) 1.47
Detection of prostatic cells in peripheral blood: correlation with serum concentrations of prostate-specific antigen. Clin Chem (1995) 1.46
Three assays for glycohemoglobin compared. Clin Chem (1995) 1.45
Correlation of HbA1C, glycated serum proteins and albumin, and fructosamine with the 24-h glucose profile of insulin-dependent pregnant diabetics. Clin Chem (1989) 1.45
Uukuniemi virus maturation: immunofluorescence microscopy with monoclonal glycoprotein-specific antibodies. J Virol (1984) 1.40
CEA, CA 19-9 and CA 72-4 improve the diagnostic accuracy in gastrointestinal cancers. Anticancer Res (2002) 1.36
Anti-Müllerian hormone inhibits initiation of growth of human primordial ovarian follicles in vitro. Hum Reprod (2006) 1.35
Elevated interleukin-6 plasma levels are regulated by the promoter region polymorphism of the IL6 gene in primary Sjögren's syndrome and correlate with the clinical manifestations of the disease. Rheumatology (Oxford) (2001) 1.31
In vitro stability of free prostate-specific antigen (PSA) and prostate-specific antigen (PSA) complexed to alpha 1-antichymotrypsin in blood samples. Urology (1996) 1.27
Polymorphisms of the interleukin-1 gene complex in schizophrenia. Mol Psychiatry (1999) 1.27
Clinical features of primary ovarian failure caused by a point mutation in the follicle-stimulating hormone receptor gene. J Clin Endocrinol Metab (1996) 1.27
Excretion of a tumor-associated trypsin inhibitor (TATI) in urine of patients with gynecological malignancy. Int J Cancer (1983) 1.27
Purification and characterization of different molecular forms of prostate-specific antigen in human seminal fluid. Clin Chem (1995) 1.21
Leptin is associated with increased prostate cancer risk: a nested case-referent study. J Clin Endocrinol Metab (2001) 1.20
Purification and characterization of a tumor-associated trypsin inhibitor from the urine of a patient with ovarian cancer. J Biol Chem (1982) 1.20
The oocyte and its role in regulating ovulation rate: a new paradigm in reproductive biology. Reproduction (2004) 1.19
Human growth differentiation factor 9 (GDF-9) and its novel homolog GDF-9B are expressed in oocytes during early folliculogenesis. J Clin Endocrinol Metab (1999) 1.19
Activation of type IV procollagenases by human tumor-associated trypsin-2. J Biol Chem (1997) 1.19
Cross-reactive cytotoxic responses. H-2 restricted are more specific than anti-H-2 responses. J Exp Med (1978) 1.17
Production of tumour necrosis factor and interleukin 1 by monocytes of patients with previous Yersinia arthritis. Clin Exp Immunol (1988) 1.16
Immunochemical demonstration of an ovarian cancer-associated urinary peptide. Int J Cancer (1982) 1.16
Tumor necrosis factor as a potent inhibitor of adrenocorticotropin-induced cortisol production and steroidogenic P450 enzyme gene expression in cultured human fetal adrenal cells. Endocrinology (1991) 1.15
A novel growth differentiation factor-9 (GDF-9) related factor is co-expressed with GDF-9 in mouse oocytes during folliculogenesis. Mech Dev (1998) 1.15
Indoleamine 2,3-dioxygenase activity in nonagenarians is markedly increased and predicts mortality. Mech Ageing Dev (2006) 1.14
Transvaginal sonography and serum hCG in monitoring of presumed ectopic pregnancies selected for expectant management. Ultrasound Obstet Gynecol (1995) 1.13
Retinoic acid activates interferon regulatory factor-1 gene expression in myeloid cells. Blood (1996) 1.13
Polymorphism of the interleukin-10 gene is associated with susceptibility to Epstein-Barr virus infection. J Infect Dis (1999) 1.12
Elevation of free beta subunit of human choriogonadotropin and core beta fragment of human choriogonadotropin in the serum and urine of patients with malignant pancreatic and biliary disease. Cancer Res (1992) 1.11
A rare allele combination of the interleukin-1 gene complex is associated with high interleukin-1 beta plasma levels in healthy individuals. Eur Cytokine Netw (2000) 1.11
Human ovarian tumor-associated trypsin. Its purification and characterization from mucinous cyst fluid and identification as an activator of pro-urokinase. J Biol Chem (1989) 1.11
Allergic sensitization and microbial load--a comparison between Finland and Russian Karelia. Clin Exp Immunol (2007) 1.10
Free, complexed and total serum prostate specific antigen: the establishment of appropriate reference ranges for their concentrations and ratios. J Urol (1995) 1.10
European randomized study of prostate cancer screening: first-year results of the Finnish trial. Br J Cancer (1999) 1.09
Evidence for oligomeric IgA production by peripheral rat lymph nodes. Nature (1974) 1.09
Tumor-associated trypsin participates in cancer cell-mediated degradation of extracellular matrix. Cancer Res (1991) 1.07
Tumour-associated trypsin inhibitor, TATI, in patients with pancreatic cancer, pancreatitis and benign biliary diseases. Br J Cancer (1986) 1.06
New nomenclature for the human tissue kallikrein gene family. Clin Chem (2000) 1.06
Use of a rapid hCG-beta-subunit radioimmunoassay in acute gynaecological emergencies. Lancet (1980) 1.05
Comparison of serous and mucinous ovarian carcinomas: distinct pattern of allelic loss at distal 8p and expression of transcription factor GATA-4. Lab Invest (2001) 1.05
Measles virus infection enhances IL-1 beta but reduces tumor necrosis factor-alpha expression in human monocytes. J Immunol (1992) 1.04
Validity of the prostate specific antigen test for prostate cancer screening: followup study with a bank of 21,000 sera in Finland. J Urol (2001) 1.04
Indoleamine 2,3-dioxygenase enzyme activity correlates with risk factors for atherosclerosis: the Cardiovascular Risk in Young Finns Study. Clin Exp Immunol (2007) 1.03
Bmp15 mutations and ovarian function. Mol Cell Endocrinol (2002) 1.02
Serum levels of human chorionic gonadotropin in nonpregnant women and men are modulated by gonadotropin-releasing hormone and sex steroids. J Clin Endocrinol Metab (1987) 1.01
Disappearance of human chorionic gonadotropin and its alpha- and beta-subunits after term pregnancy. Clin Chem (1997) 1.01
Transcription factors GATA-4 and GATA-6 and a GATA family cofactor, FOG-2, are expressed in human ovary and sex cord-derived ovarian tumors. J Clin Endocrinol Metab (2000) 1.01
The IL1A genotype is associated with nasal polyposis in asthmatic adults. Allergy (2003) 1.01
Differential hormonal regulation of vascular endothelial growth factors VEGF, VEGF-B, and VEGF-C messenger ribonucleic acid levels in cultured human granulosa-luteal cells. Endocrinology (1997) 1.01
The promoter polymorphism of the interleukin-6 gene regulates interleukin-6 production in neonates but not in adults. Eur Cytokine Netw (2001) 1.00
Human colon carcinoma, fibrosarcoma and leukemia cell lines produce tumor-associated trypsinogen. Int J Cancer (1991) 0.99
Bilateral Achilles tendon rupture: a report on two cases. Scand J Med Sci Sports (1996) 0.99
Time-resolved immunofluorometric assays for trypsinogen-1 and 2 in serum reveal preferential elevation of trypsinogen-2 in pancreatitis. J Lab Clin Med (1990) 0.99
Interaction between 5-HT1A and BDNF genotypes increases the risk of treatment-resistant depression. J Neural Transm (Vienna) (2007) 0.99
Indoleamine 2,3-dioxygenase activity is increased in patients with systemic lupus erythematosus and predicts disease activation in the sunny season. Clin Exp Immunol (2007) 0.99
Tumour-associated trypsin inhibitor (TATI) in human ovarian cyst fluid. Comparison with CA 125 and CEA. Br J Cancer (1987) 0.98
Gonadotrophin stimulation of non-luteinized granulosa cells increases steroid production and the expression of enzymes involved in estrogen and progesterone synthesis. Hum Reprod (2006) 0.98
Polymorphisms within the tumor necrosis factor locus and prevalence of coronary artery disease in middle-aged men. Atherosclerosis (2001) 0.98
Severe sciatica: a 13-year follow-up of 342 patients. Eur Spine J (1995) 0.97
Interleukin-6 and interleukin-1 receptor antagonist in cerebrospinal fluid from patients with recent tonic-clonic seizures. Epilepsy Res (2000) 0.97
Signal transduction pathways leading to the production of IL-8 by human monocytes are differentially regulated by dexamethasone. Clin Exp Immunol (1992) 0.97
Double-label time-resolved immunofluorometric assay of prostate-specific antigen and of its complex with alpha 1-antichymotrypsin. Clin Chem (1993) 0.97
The multifidus muscle in patients with lumbar disc herniation. A histochemical and morphometric analysis of intraoperative biopsies. Spine (Phila Pa 1976) (1986) 0.97
Suspected ectopic pregnancy: ultrasound findings and hCG levels assessed by an immunofluorometric assay. Br J Obstet Gynaecol (1988) 0.97
Dendritic cells in human peripheral blood: effective enrichment from the nonadherent cells. Immunol Lett (1987) 0.97
Anti-inflammatory cytokine response and the development of multiple organ failure in severe sepsis. Acta Anaesthesiol Scand (2003) 0.96
Optimization of a time-resolved immunofluorometric assay for tumor-associated trypsin inhibitor (TATI) using the streptavidin-biotin system. J Immunol Methods (1993) 0.96
Association of interferon-gamma +874(T/A) single nucleotide polymorphism with the rate of tryptophan catabolism in healthy individuals. Scand J Immunol (2005) 0.96
Interleukin-10 gene promoter region polymorphism is associated with eosinophil count and circulating immunoglobulin E in adult asthma. Clin Exp Allergy (2003) 0.96
Oocyte-expressed genes affecting ovulation rate. Mol Cell Endocrinol (2005) 0.96
Analysis of Campylobacter jejuni antigens with monoclonal antibodies. J Clin Microbiol (1984) 0.95
Preoperative serum concentration of hCGbeta as a prognostic factor in ovarian cancer. Int J Cancer (2001) 0.95
cDNA cloning, expression studies and chromosome mapping of human type I serine/threonine kinase receptor ALK7 (ACVR1C). Cytogenet Cell Genet (2001) 0.95
Susceptibility to primary Epstein-Barr virus infection is associated with interleukin-10 gene promoter polymorphism. J Infect Dis (2001) 0.95
Serum human chorionic gonadotropin dynamics during spontaneous resolution of ectopic pregnancy. Fertil Steril (1994) 0.95
Genetic differences in the cyclophosphamide-induced immune suppression: weaker suppression of T-cell cytotoxicity by cyclophosphamide activated by CBA mice. Clin Immunol Immunopathol (1980) 0.95
Polymorphism of the cytokine genes in hospitalized patients with Puumala hantavirus infection. Nephrol Dial Transplant (2001) 0.94