Published in Cell on November 13, 1992
The ankyrin repeat as molecular architecture for protein recognition. Protein Sci (2004) 5.07
Autoregulation of I kappa B alpha activity. Proc Natl Acad Sci U S A (1994) 3.24
A core transcriptional network for early mesoderm development in Drosophila melanogaster. Genes Dev (2007) 3.01
Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B. Mol Cell Biol (1995) 2.69
The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae. J Cell Biol (1995) 2.69
Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila. EMBO J (1995) 2.48
A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF. EMBO J (1999) 1.99
Mitochondria-to-nuclear signaling is regulated by the subcellular localization of the transcription factors Rtg1p and Rtg3p. Mol Biol Cell (2000) 1.98
The bcl-3 proto-oncogene encodes a nuclear I kappa B-like molecule that preferentially interacts with NF-kappa B p50 and p52 in a phosphorylation-dependent manner. Mol Cell Biol (1993) 1.93
Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos. Genes Dev (1998) 1.82
Common structural constituents confer I kappa B activity to NF-kappa B p105 and I kappa B/MAD-3. EMBO J (1993) 1.77
Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation. Mol Cell Biol (1996) 1.73
Dissociation of the dorsal-cactus complex and phosphorylation of the dorsal protein correlate with the nuclear localization of dorsal. J Cell Biol (1993) 1.70
In vivo stimulation of I kappa B phosphorylation is not sufficient to activate NF-kappa B. Mol Cell Biol (1995) 1.64
The oncoprotein Bcl-3 can facilitate NF-kappa B-mediated transactivation by removing inhibiting p50 homodimers from select kappa B sites. EMBO J (1993) 1.61
The regulation of protein transport to the nucleus by phosphorylation. Biochem J (1995) 1.52
NF-κB/Rel proteins and the humoral immune responses of Drosophila melanogaster. Curr Top Microbiol Immunol (2011) 1.45
Human T-cell leukemia virus type I Tax associates with and is negatively regulated by the NF-kappa B2 p100 gene product: implications for viral latency. Mol Cell Biol (1994) 1.45
Domain organization of I kappa B alpha and sites of interaction with NF-kappa B p65. Mol Cell Biol (1995) 1.44
The dorsal-related immunity factor, Dif, is a sequence-specific trans-activator of Drosophila Cecropin gene expression. EMBO J (1995) 1.43
A heterotrimeric death domain complex in Toll signaling. Proc Natl Acad Sci U S A (2002) 1.35
The Schizosaccharomyces pombe MBF complex requires heterodimerization for entry into S phase. Mol Cell Biol (1995) 1.31
Two distinct mechanisms contribute to the constitutive activation of RelB in lymphoid cells. EMBO J (1994) 1.30
BZP, a novel serum-responsive zinc finger protein that inhibits gene transcription. Mol Cell Biol (1994) 1.28
Dorsal, a Drosophila Rel-like protein, is phosphorylated upon activation of the transmembrane protein Toll. Mol Cell Biol (1994) 1.28
BCL3 encodes a nuclear protein which can alter the subcellular location of NF-kappa B proteins. Mol Cell Biol (1994) 1.22
A conserved signal transduction pathway regulating the activity of the rel-like proteins dorsal and NF-kappa B. Mol Biol Cell (1993) 1.18
Interactions between the ankyrin repeat-containing protein Akr1p and the pheromone response pathway in Saccharomyces cerevisiae. Mol Cell Biol (1996) 1.15
Genetic characterization of tube and pelle, genes required for signaling between Toll and dorsal in the specification of the dorsal-ventral pattern of the Drosophila embryo. Genetics (1993) 1.13
Ventralization of the Drosophila embryo by deletion of extracellular leucine-rich repeats in the Toll protein. Mol Biol Cell (1995) 1.13
Interactions of a Rel protein with its inhibitor. Proc Natl Acad Sci U S A (1995) 1.11
Uncoupling gastrulation and mesoderm differentiation in the Drosophila embryo. EMBO J (1994) 1.06
Ankyrin and beta-spectrin accumulate independently of alpha-spectrin in Drosophila. Proc Natl Acad Sci U S A (1994) 1.05
Nuclear import of the Drosophila Rel protein Dorsal is regulated by phosphorylation. Genes Dev (1999) 1.05
Purification, reconstitution, and I kappa B association of the c-Rel-p65 (RelA) complex, a strong activator of transcription. Mol Cell Biol (1994) 1.04
A role for CKII phosphorylation of the cactus PEST domain in dorsoventral patterning of the Drosophila embryo. Genes Dev (1997) 1.03
Disulfide cross-linking in crude embryonic lysates reveals three complexes of the Drosophila morphogen dorsal and its inhibitor cactus. Proc Natl Acad Sci U S A (1994) 1.01
Specificity of Rel-inhibitor interactions in Drosophila embryos. Mol Cell Biol (1995) 1.00
The inhibitor of DNA replication encoded by the Drosophila gene plutonium is a small, ankyrin repeat protein. EMBO J (1994) 1.00
Retinoic acid induction of major histocompatibility complex class I genes in NTera-2 embryonal carcinoma cells involves induction of NF-kappa B (p50-p65) and retinoic acid receptor beta-retinoid X receptor beta heterodimers. Mol Cell Biol (1993) 1.00
A genomewide survey of developmentally relevant genes in Ciona intestinalis. III. Genes for Fox, ETS, nuclear receptors and NFkappaB. Dev Genes Evol (2003) 0.98
A homolog of human transcription factor NF-X1 encoded by the Drosophila shuttle craft gene is required in the embryonic central nervous system. Mol Cell Biol (1996) 0.97
Shark, a Src homology 2, ankyrin repeat, tyrosine kinase, is expressed on the apical surfaces of ectodermal epithelia. Proc Natl Acad Sci U S A (1995) 0.96
Inhibition of NF-kappaB activity by IkappaBbeta in association with kappaB-Ras. Mol Cell Biol (2004) 0.96
Regulated nuclear import of the Drosophila rel protein dorsal: structure-function analysis. Mol Cell Biol (1996) 0.95
Purification and characterization of a 59-kilodalton protein that specifically binds to NF-kappa B-binding motifs of the defense protein genes of Sarcophaga peregrina (the flesh fly). Mol Cell Biol (1993) 0.94
Avian I kappa B alpha is transcriptionally induced by c-Rel and v-Rel with different kinetics. J Virol (1995) 0.94
Polydnaviral ankyrin proteins aid parasitic wasp survival by coordinate and selective inhibition of hematopoietic and immune NF-kappa B signaling in insect hosts. PLoS Pathog (2013) 0.94
Domain mapping of tube, a protein essential for dorsoventral patterning of the Drosophila embryo. EMBO J (1993) 0.92
In vivo evolution of c-rel oncogenic potential. J Virol (1994) 0.92
The relocalization of v-Rel from the nucleus to the cytoplasm coincides with induction of expression of Ikba and nfkb1 and stabilization of I kappa B-alpha. J Virol (1995) 0.88
A multimeric complex and the nuclear targeting of the Drosophila Rel protein Dorsal. Proc Natl Acad Sci U S A (1997) 0.87
Domains of p85cdc10 required for function of the fission yeast DSC-1 factor. Nucleic Acids Res (1993) 0.86
The Dorsal Rel homology domain plays an active role in transcriptional regulation. Mol Cell Biol (2002) 0.86
The thick veins gene of Drosophila is required for dorsoventral polarity of the embryo. Genetics (1994) 0.86
Divergences in protein activity and cellular localization within the Campoletis sonorensis Ichnovirus Vankyrin family. J Virol (2006) 0.83
GAL4-I kappa B alpha and GAL4-I kappa B gamma activate transcription by different mechanisms. Nucleic Acids Res (1993) 0.83
Identification, characterization, and function analysis of the Cactus gene from Litopenaeus vannamei. PLoS One (2012) 0.83
Notch and PKC are involved in formation of the lateral region of the dorso-ventral axis in Drosophila embryos. PLoS One (2013) 0.81
The IRAK homolog Pelle is the functional counterpart of IκB kinase in the Drosophila Toll pathway. PLoS One (2013) 0.80
Relocalization of Drosophila dorsal protein can be induced by a rise in cytoplasmic calcium concentration and the expression of constitutively active but not wild-type Toll receptors. Biochem J (1993) 0.80
From Drosophila development to adult: clues to Notch function in long-term memory. Front Cell Neurosci (2013) 0.80
Regulation of nuclear factor κB (NF-κB) transcriptional activity via p65 acetylation by the chaperonin containing TCP1 (CCT). PLoS One (2012) 0.80
The dorsal protein enhances the biosynthesis and stability of the Drosophila I kappa B homologue cactus. Nucleic Acids Res (1995) 0.80
Maternal control of the Drosophila dorsal-ventral body axis. Wiley Interdiscip Rev Dev Biol (2014) 0.78
Calpain A modulates Toll responses by limited Cactus/IκB proteolysis. Mol Biol Cell (2013) 0.77
Alternative NF-κB Isoforms in the Drosophila Neuromuscular Junction and Brain. PLoS One (2015) 0.76
The Friend of GATA Transcriptional Co-Regulator, U-Shaped, Is a Downstream Antagonist of Dorsal-Driven Prohemocyte Differentiation in Drosophila. PLoS One (2016) 0.75
Modeling of the dorsal gradient across species reveals interaction between embryo morphology and Toll signaling pathway during evolution. PLoS Comput Biol (2014) 0.75
Annotation of the Asian Citrus Psyllid Genome Reveals a Reduced Innate Immune System. Front Physiol (2016) 0.75
Metabolic learning and memory formation by the brain influence systemic metabolic homeostasis. Nat Commun (2015) 0.75