Published in J Biol Chem on December 10, 1977
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The amino terminus of the yeast F1-ATPase beta-subunit precursor functions as a mitochondrial import signal. J Cell Biol (1986) 4.07
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A purified precursor polypeptide requires a cytosolic protein fraction for import into mitochondria. EMBO J (1984) 1.99
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The amino terminus of the yeast F1-ATPase beta-subunit precursor functions as a mitochondrial import signal. J Cell Biol (1986) 4.07
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The amino-terminal region of an imported mitochondrial precursor polypeptide can direct cytoplasmic dihydrofolate reductase into the mitochondrial matrix. EMBO J (1984) 3.69
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Different import pathways through the mitochondrial intermembrane space for inner membrane proteins. EMBO J (1999) 3.58
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Import of proteins into mitochondria. The precursor of cytochrome c1 is processed in two steps, one of them heme-dependent. J Biol Chem (1982) 3.26
Intracellular targeting and import of an F1-ATPase beta-subunit-beta-galactosidase hybrid protein into yeast mitochondria. Proc Natl Acad Sci U S A (1984) 3.02
A 70-kd protein of the yeast mitochondrial outer membrane is targeted and anchored via its extreme amino terminus. EMBO J (1984) 2.96
A chemically synthesized pre-sequence of an imported mitochondrial protein can form an amphiphilic helix and perturb natural and artificial phospholipid bilayers. EMBO J (1986) 2.91
Import of proteins into mitochondria. Partial purification of a matrix-located protease involved in cleavage of mitochondrial precursor polypeptides. J Biol Chem (1983) 2.81
The cleavable prepiece of an imported mitochondrial protein is sufficient to direct cytosolic dihydrofolate reductase into the mitochondrial matrix. FEBS Lett (1984) 2.75
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Characterization of YDJ1: a yeast homologue of the bacterial dnaJ protein. J Cell Biol (1991) 2.63
A precursor protein partly translocated into yeast mitochondria is bound to a 70 kd mitochondrial stress protein. EMBO J (1990) 2.56
Yeast mitochondrial outer membrane specifically binds cytoplasmically-synthesized precursors of mitochondrial proteins. EMBO J (1983) 2.55
Cytochrome c oxidase from bakers' yeast. I. Isolation and properties. J Biol Chem (1973) 2.50
YDJ1p facilitates polypeptide translocation across different intracellular membranes by a conserved mechanism. Cell (1992) 2.49
The outer membrane of yeast mitochondria: isolation of outside-out sealed vesicles. EMBO J (1983) 2.48
Import of proteins into mitochondria. Energy-dependent, two-step processing of the intermembrane space enzyme cytochrome b2 by isolated yeast mitochondria. J Biol Chem (1982) 2.46
Regulation of Hsp70 function by a eukaryotic DnaJ homolog. J Biol Chem (1992) 2.46
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Imported mitochondrial proteins cytochrome b2 and cytochrome c1 are processed in two steps. Proc Natl Acad Sci U S A (1982) 2.39
Mitochondrial proteins essential for viability mediate protein import into yeast mitochondria. Nature (1991) 2.37
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Import of proteins into mitochondria. Yeast cells grown in the presence of carbonyl cyanide m-chlorophenylhydrazone accumulate massive amounts of some mitochondrial precursor polypeptides. J Biol Chem (1982) 2.34
Import of proteins into mitochondria: a 70 kilodalton outer membrane protein with a large carboxy-terminal deletion is still transported to the outer membrane. EMBO J (1983) 2.33
Isolation of the nuclear yeast genes for citrate synthase and fifteen other mitochondrial proteins by a new screening method. EMBO J (1984) 2.33
A neutral metallo endoprotease involved in the processing of an F1-ATPase subunit precursor in mitochondria. J Biol Chem (1982) 2.28
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Sequential action of mitochondrial chaperones in protein import into the matrix. EMBO J (1991) 2.27
Heme is necessary for the accumulation and assembly of cytochrome c oxidase subunits in Saccharomyces cerevisiae. J Biol Chem (1978) 2.25
Protein import into yeast mitochondria is accelerated by the outer membrane protein MAS70. EMBO J (1990) 2.22
An essential yeast gene with homology to the exonuclease-encoding XRN1/KEM1 gene also encodes a protein with exoribonuclease activity. Mol Cell Biol (1993) 2.20
A 42K outer-membrane protein is a component of the yeast mitochondrial protein import site. Nature (1989) 2.18
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The presequences of two imported mitochondrial proteins contain information for intracellular and intramitochondrial sorting. Cell (1986) 2.14
Energy-dependent processing of cytoplasmically made precursors to mitochondrial proteins. Proc Natl Acad Sci U S A (1979) 2.14
Import of proteins into mitochondria. Extramitochondrial pools and post-translational import of mitochondrial protein precursors in vivo. J Biol Chem (1982) 2.12
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A conserved HPD sequence of the J-domain is necessary for YDJ1 stimulation of Hsp70 ATPase activity at a site distinct from substrate binding. J Biol Chem (1996) 2.09
Both ATP and an energized inner membrane are required to import a purified precursor protein into mitochondria. EMBO J (1987) 2.08
The first twelve amino acids of a yeast mitochondrial outer membrane protein can direct a nuclear-coded cytochrome oxidase subunit to the mitochondrial inner membrane. EMBO J (1985) 2.06
A yeast mutant lacking mitochondrial manganese-superoxide dismutase is hypersensitive to oxygen. Proc Natl Acad Sci U S A (1986) 2.01
A purified precursor polypeptide requires a cytosolic protein fraction for import into mitochondria. EMBO J (1984) 1.99
Protein import into mitochondria: ATP-dependent protein translocation activity in a submitochondrial fraction enriched in membrane contact sites and specific proteins. J Cell Biol (1989) 1.98
Subunit IV of yeast cytochrome c oxidase: cloning and nucleotide sequencing of the gene and partial amino acid sequencing of the mature protein. EMBO J (1984) 1.97
Import of proteins into mitochondria: nucleotide sequence of the gene for a 70-kd protein of the yeast mitochondrial outer membrane. EMBO J (1983) 1.97
MAS1, a gene essential for yeast mitochondrial assembly, encodes a subunit of the mitochondrial processing protease. EMBO J (1988) 1.95
DNA-protein conjugates can enter mitochondria via the protein import pathway. Nature (1989) 1.95
Amphiphilicity is essential for mitochondrial presequence function. EMBO J (1988) 1.93
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A two-subunit cytochrome c oxidase (cytochrome aa3) from Paracoccus dentrificans. Proc Natl Acad Sci U S A (1980) 1.88
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Dynamic interaction between Isp45 and mitochondrial hsp70 in the protein import system of the yeast mitochondrial inner membrane. Proc Natl Acad Sci U S A (1994) 1.87
Import of proteins into yeast mitochondria: the purified matrix processing protease contains two subunits which are encoded by the nuclear MAS1 and MAS2 genes. EMBO J (1988) 1.87
Farnesylation of YDJ1p is required for function at elevated growth temperatures in Saccharomyces cerevisiae. J Biol Chem (1992) 1.87
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Protein unfolding and the energetics of protein translocation across biological membranes. Cell (1988) 1.84
A chimeric mitochondrial precursor protein with internal disulfide bridges blocks import of authentic precursors into mitochondria and allows quantitation of import sites. J Cell Biol (1988) 1.83
A yeast mitochondrial outer membrane protein essential for protein import and cell viability. Nature (1990) 1.82
Requirement for the yeast gene LON in intramitochondrial proteolysis and maintenance of respiration. Science (1994) 1.82
Promitochondria of anaerobically grown yeast. I. Isolation and biochemical properties. Biochemistry (1969) 1.79
Unfolding and refolding of a purified precursor protein during import into isolated mitochondria. EMBO J (1988) 1.75
The cytoplasmically-made subunit IV is necessary for assembly of cytochrome c oxidase in yeast. EMBO J (1985) 1.75
Comparison of the response to the prone position between pulmonary and extrapulmonary acute respiratory distress syndrome. Intensive Care Med (2001) 1.72
Cytochrome c oxidase from bakers' yeast. II. Site of translation of the protein components. J Biol Chem (1973) 1.71
Functional cooperation of mitochondrial protein import receptors in yeast. EMBO J (1993) 1.71
Import of proteins into mitochondria. Translatable mRNAs for imported mitochondrial proteins are present in free as well as mitochondria-bound cytoplasmic polysomes. J Biol Chem (1982) 1.70
Energy transfer and charge separation kinetics in photosystem I: Part 1: Picosecond transient absorption and fluorescence study of cyanobacterial photosystem I particles. Biophys J (1993) 1.69
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The protein import receptor of mitochondria. Trends Biochem Sci (1995) 1.68
Identification of a 45-kDa protein at the protein import site of the yeast mitochondrial inner membrane. Proc Natl Acad Sci U S A (1992) 1.67
A yeast mutant temperature-sensitive for mitochondrial assembly is deficient in a mitochondrial protease activity that cleaves imported precursor polypeptides. EMBO J (1985) 1.66
Clinical course and lung function change of idiopathic nonspecific interstitial pneumonia. Eur Respir J (2008) 1.65
Biogenesis of porin of the outer mitochondrial membrane involves an import pathway via receptors and the general import pore of the TOM complex. J Cell Biol (2001) 1.65
Active unfolding of precursor proteins during mitochondrial protein import. EMBO J (1997) 1.62
Sequencing of the nuclear gene for the yeast cytochrome c1 precursor reveals an unusually complex amino-terminal presequence. EMBO J (1984) 1.61
Cytochrome c oxidase from bakers' yeast. IV. Immunological evidence for the participation of a mitochondrially synthesized subunit in enzymatic activity. J Biol Chem (1975) 1.61
Cyclophilin catalyzes protein folding in yeast mitochondria. Proc Natl Acad Sci U S A (1995) 1.60
A mitochondrial homolog of bacterial GrpE interacts with mitochondrial hsp70 and is essential for viability. EMBO J (1994) 1.60
17th Sir Hans Krebs lecture. Signals guiding proteins to their correct locations in mitochondria. Eur J Biochem (1987) 1.60
Phosphodiester bond cleavage outside mitochondria is required for the completion of protein import into the mitochondrial matrix. Cell (1987) 1.59