Published in Development on October 22, 2003
Vascular remodeling of the mouse yolk sac requires hemodynamic force. Development (2007) 3.26
Functional modulation of cardiac form through regionally confined cell shape changes. PLoS Biol (2007) 2.05
The effects of hemodynamic force on embryonic development. Microcirculation (2010) 1.66
Piezo1, a mechanically activated ion channel, is required for vascular development in mice. Proc Natl Acad Sci U S A (2014) 1.57
Tropomodulin1 is required in the heart but not the yolk sac for mouse embryonic development. Circ Res (2008) 1.22
Absence of heartbeat in the Xenopus tropicalis mutation muzak is caused by a nonsense mutation in cardiac myosin myh6. Dev Biol (2009) 1.20
Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling. EMBO J (2009) 1.15
Dynamic responses of endothelial cells to changes in blood flow during vascular remodeling of the mouse yolk sac. Development (2013) 1.13
Depletion of zebrafish essential and regulatory myosin light chains reduces cardiac function through distinct mechanisms. Cardiovasc Res (2008) 1.11
Cardiovascular assessment of fetal mice by in utero echocardiography. Ultrasound Med Biol (2008) 1.08
FGF-16 is required for embryonic heart development. Biochem Biophys Res Commun (2008) 1.08
High-purity enrichment of functional cardiovascular cells from human iPS cells. Cardiovasc Res (2012) 1.07
Understanding vascular development. Wiley Interdiscip Rev Dev Biol (2012) 1.02
Repression of arterial genes in hemogenic endothelium is sufficient for haematopoietic fate acquisition. Nat Commun (2015) 0.97
Line-scanning particle image velocimetry: an optical approach for quantifying a wide range of blood flow speeds in live animals. PLoS One (2012) 0.93
Engineering of arteries in vitro. Cell Mol Life Sci (2014) 0.92
Mammalian formin Fhod3 plays an essential role in cardiogenesis by organizing myofibrillogenesis. Biol Open (2012) 0.91
Mechanotransduction in embryonic vascular development. Biomech Model Mechanobiol (2012) 0.90
Heavy and light roles: myosin in the morphogenesis of the heart. Cell Mol Life Sci (2012) 0.89
Vascular development and hemodynamic force in the mouse yolk sac. Front Physiol (2014) 0.88
Functions of myosin light chain-2 (MYL2) in cardiac muscle and disease. Gene (2015) 0.88
Combinatorial polymer matrices enhance in vitro maturation of human induced pluripotent stem cell-derived cardiomyocytes. Biomaterials (2015) 0.86
Intracardiac flow dynamics regulate atrioventricular valve morphogenesis. Cardiovasc Res (2014) 0.86
Endothelium as master regulator of organ development and growth. Vascul Pharmacol (2008) 0.86
Hadp1, a newly identified pleckstrin homology domain protein, is required for cardiac contractility in zebrafish. Dis Model Mech (2011) 0.85
Extracellular matrix and the mechanics of large artery development. Biomech Model Mechanobiol (2012) 0.84
Lrrc10 is required for early heart development and function in zebrafish. Dev Biol (2007) 0.83
Trastuzumab alters the expression of genes essential for cardiac function and induces ultrastructural changes of cardiomyocytes in mice. PLoS One (2013) 0.82
Investigating developmental cardiovascular biomechanics and the origins of congenital heart defects. Front Physiol (2014) 0.82
3-OST-7 regulates BMP-dependent cardiac contraction. PLoS Biol (2013) 0.81
Adult cardiac expression of the activating transcription factor 3, ATF3, promotes ventricular hypertrophy. PLoS One (2013) 0.81
The functional diversity of essential genes required for mammalian cardiac development. Genesis (2014) 0.79
β-Lapachone induces heart morphogenetic and functional defects by promoting the death of erythrocytes and the endocardium in zebrafish embryos. J Biomed Sci (2011) 0.79
Formation, contraction, and mechanotransduction of myofribrils in cardiac development: clues from genetics. Biochem Res Int (2012) 0.76
Growth and hemodynamics after early embryonic aortic arch occlusion. Biomech Model Mechanobiol (2014) 0.75
Cardiovascular Patterning as Determined by Hemodynamic Forces and Blood Vessel Genetics. PLoS One (2015) 0.75
Depletion of Tip60 from In Vivo Cardiomyocytes Increases Myocyte Density, Followed by Cardiac Dysfunction, Myocyte Fallout and Lethality. PLoS One (2016) 0.75
Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion. Cell Rep (2016) 0.75
Abnormal arterial-venous fusions and fate specification in mouse embryos lacking blood flow. Sci Rep (2017) 0.75
Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Nature (2005) 9.44
Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. Dev Cell (2003) 8.00
A myocardial lineage derives from Tbx18 epicardial cells. Nature (2008) 6.15
Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy. Nat Cell Biol (2011) 4.64
Superoxide flashes in single mitochondria. Cell (2008) 4.08
ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell (2005) 3.96
Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling. J Clin Invest (2006) 3.72
ErbB2 is essential in the prevention of dilated cardiomyopathy. Nat Med (2002) 3.36
Vascular remodeling of the mouse yolk sac requires hemodynamic force. Development (2007) 3.26
Mutations in Cypher/ZASP in patients with dilated cardiomyopathy and left ventricular non-compaction. J Am Coll Cardiol (2003) 3.20
Selective stimulation of astrocyte calcium in situ does not affect neuronal excitatory synaptic activity. Neuron (2007) 3.15
Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice. Proc Natl Acad Sci U S A (2002) 3.13
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. J Clin Invest (2009) 2.98
Islet 1 is expressed in distinct cardiovascular lineages, including pacemaker and coronary vascular cells. Dev Biol (2006) 2.81
Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits. Cell (2013) 2.43
Endothelin-1-induced arrhythmogenic Ca2+ signaling is abolished in atrial myocytes of inositol-1,4,5-trisphosphate(IP3)-receptor type 2-deficient mice. Circ Res (2005) 2.42
Required, tissue-specific roles for Fgf8 in outflow tract formation and remodeling. Development (2006) 2.41
Cardiac myocyte-specific excision of the beta1 integrin gene results in myocardial fibrosis and cardiac failure. Circ Res (2002) 2.36
An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice. J Clin Invest (2008) 2.19
Gap junctions in the inner ear: comparison of distribution patterns in different vertebrates and assessement of connexin composition in mammals. J Comp Neurol (2003) 2.18
Inducible cardiac-restricted expression of enteroviral protease 2A is sufficient to induce dilated cardiomyopathy. Circulation (2006) 2.07
Isl1Cre reveals a common Bmp pathway in heart and limb development. Development (2006) 2.04
MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. J Clin Invest (2010) 2.04
Nebulin-deficient mice exhibit shorter thin filament lengths and reduced contractile function in skeletal muscle. J Cell Biol (2006) 2.00
Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects. Am J Physiol Heart Circ Physiol (2007) 1.99
T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis. Development (2005) 1.92
Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release. Nat Med (2011) 1.88
Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart. EMBO J (2004) 1.88
Loss of enigma homolog protein results in dilated cardiomyopathy. Circ Res (2010) 1.85
The guanine cation radical: investigation of deprotonation states by ESR and DFT. J Phys Chem B (2006) 1.83
Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis. J Clin Invest (2014) 1.82
Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis. Proc Natl Acad Sci U S A (2007) 1.80
In vivo cardiac reprogramming contributes to zebrafish heart regeneration. Nature (2013) 1.79
Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene. J Mol Cell Cardiol (2009) 1.72
Type 1 IP3 receptors activate BKCa channels via local molecular coupling in arterial smooth muscle cells. J Gen Physiol (2010) 1.71
Involvement of estrogen receptor beta in terminal differentiation of mammary gland epithelium. Proc Natl Acad Sci U S A (2002) 1.63
Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice. J Clin Invest (2005) 1.61
Simple and high yielding method for preparing tissue specific extracellular matrix coatings for cell culture. PLoS One (2010) 1.60
Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease. J Clin Invest (2012) 1.59
Stabilization of the coronary sinus electrode position with coronary stent implantation to prevent and treat dislocation. J Cardiovasc Electrophysiol (2007) 1.49
Nesprin 1 is critical for nuclear positioning and anchorage. Hum Mol Genet (2009) 1.48
Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice. Proc Natl Acad Sci U S A (2008) 1.48
In vivo stimulus-induced vasodilation occurs without IP3 receptor activation and may precede astrocytic calcium increase. J Neurosci (2013) 1.47
Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte function. J Clin Invest (2011) 1.46
Points of view: a survey of survey courses: are they effective? Cell Biol Educ (2005) 1.46
Biological activities of fibroblast growth factor-2 in the adult myocardium. Cardiovasc Res (2003) 1.46
Atrial chamber-specific expression of sarcolipin is regulated during development and hypertrophic remodeling. J Biol Chem (2003) 1.44
Formation of 8-oxo-7,8-dihydroguanine-radicals in gamma-irradiated DNA by multiple one-electron oxidations. Nucleic Acids Res (2004) 1.44
Dynamics of Z-band based proteins in developing skeletal muscle cells. Cell Motil Cytoskeleton (2005) 1.43
Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes. Nature (2012) 1.42
UVA-visible photo-excitation of guanine radical cations produces sugar radicals in DNA and model structures. Nucleic Acids Res (2005) 1.42
Blockade of NOX2 and STIM1 signaling limits lipopolysaccharide-induced vascular inflammation. J Clin Invest (2013) 1.40
Obscurin determines the architecture of the longitudinal sarcoplasmic reticulum. J Cell Sci (2009) 1.40
Dilated cardiomyopathy in Erb-b4-deficient ventricular muscle. Am J Physiol Heart Circ Physiol (2005) 1.35
Cell-cell connection to cardiac disease. Trends Cardiovasc Med (2009) 1.34
Pitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardium. Dev Biol (2006) 1.32
Meta-analysis of cotton fiber quality QTLs across diverse environments in a Gossypium hirsutum x G. barbadense RIL population. BMC Plant Biol (2010) 1.32
Imaging superoxide flash and metabolism-coupled mitochondrial permeability transition in living animals. Cell Res (2011) 1.32
E-Tmod capping of actin filaments at the slow-growing end is required to establish mouse embryonic circulation. Am J Physiol Heart Circ Physiol (2003) 1.31
Rapid muscle-specific gene expression changes after a single bout of eccentric contractions in the mouse. Am J Physiol Cell Physiol (2003) 1.30
alpha-E-catenin inactivation disrupts the cardiomyocyte adherens junction, resulting in cardiomyopathy and susceptibility to wall rupture. Circulation (2006) 1.28
PINCH1 plays an essential role in early murine embryonic development but is dispensable in ventricular cardiomyocytes. Mol Cell Biol (2005) 1.27
Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice. J Neurosci (2010) 1.25
Sterol regulatory element binding protein 2 activation of NLRP3 inflammasome in endothelium mediates hemodynamic-induced atherosclerosis susceptibility. Circulation (2013) 1.25
FHL2 inhibits the activated osteoclast in a TRAF6-dependent manner. J Clin Invest (2005) 1.25
Structural and regulatory roles of muscle ankyrin repeat protein family in skeletal muscle. Am J Physiol Cell Physiol (2007) 1.25
Reduced thin filament length in nebulin-knockout skeletal muscle alters isometric contractile properties. Am J Physiol Cell Physiol (2009) 1.24
A Cypher/ZASP mutation associated with dilated cardiomyopathy alters the binding affinity to protein kinase C. J Biol Chem (2003) 1.23
Bicarbonate enhances peroxidase activity of Cu,Zn-superoxide dismutase. Role of carbonate anion radical and scavenging of carbonate anion radical by metalloporphyrin antioxidant enzyme mimetics. J Biol Chem (2001) 1.22
Embryonic survival and severity of cardiac and craniofacial defects are affected by genetic background in fibroblast growth factor-16 null mice. DNA Cell Biol (2010) 1.22
Cardiac-specific ablation of Cypher leads to a severe form of dilated cardiomyopathy with premature death. Hum Mol Genet (2008) 1.22
Isl1 is upstream of sonic hedgehog in a pathway required for cardiac morphogenesis. Dev Biol (2006) 1.21
Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart. J Clin Invest (2008) 1.18
Smad7 is required for the development and function of the heart. J Biol Chem (2008) 1.18
Pinch1 is required for normal development of cranial and cardiac neural crest-derived structures. Circ Res (2007) 1.15
Restoration of deficient membrane proteins in the cardiomyopathic hamster by in vivo cardiac gene transfer. Circulation (2002) 1.14
C5'- and C3'-sugar radicals produced via photo-excitation of one-electron oxidized adenine in 2'-deoxyadenosine and its derivatives. Nucleic Acids Res (2006) 1.14
Nuclear Ca2+ sparks and waves mediated by inositol 1,4,5-trisphosphate receptors in neonatal rat cardiomyocytes. Cell Calcium (2007) 1.14
Nebulin plays a direct role in promoting strong actin-myosin interactions. FASEB J (2009) 1.14
Characterization and in vivo functional analysis of splice variants of cypher. J Biol Chem (2002) 1.13
Genome-wide analysis of histone marks identifying an epigenetic signature of promoters and enhancers underlying cardiac hypertrophy. Proc Natl Acad Sci U S A (2013) 1.13
Epac2 mediates cardiac β1-adrenergic-dependent sarcoplasmic reticulum Ca2+ leak and arrhythmia. Circulation (2013) 1.12
A novel mechanism involving four-and-a-half LIM domain protein-1 and extracellular signal-regulated kinase-2 regulates titin phosphorylation and mechanics. J Biol Chem (2012) 1.12
Dynamic changes in connexin expression correlate with key events in the wound healing process. Cell Biol Int (2003) 1.11
Sarcoplasmic reticulum calcium defect in Ras-induced hypertrophic cardiomyopathy heart. Am J Physiol Heart Circ Physiol (2003) 1.11
Vascular endothelial-specific dimethylarginine dimethylaminohydrolase-1-deficient mice reveal that vascular endothelium plays an important role in removing asymmetric dimethylarginine. Circulation (2009) 1.10
Central role of mitofusin 2 in autophagosome-lysosome fusion in cardiomyocytes. J Biol Chem (2012) 1.10
Enhanced leptin sensitivity, reduced adiposity, and improved glucose homeostasis in mice lacking exchange protein directly activated by cyclic AMP isoform 1. Mol Cell Biol (2012) 1.09
Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality. Circulation (2009) 1.08
FGF-16 is required for embryonic heart development. Biochem Biophys Res Commun (2008) 1.08
Critical role of filamin-binding LIM protein 1 (FBLP-1)/migfilin in regulation of bone remodeling. J Biol Chem (2012) 1.07
Extracellular matrix remodeling in atrial fibrosis: mechanisms and implications in atrial fibrillation. J Mol Cell Cardiol (2009) 1.06
Thymosin beta 4 is dispensable for murine cardiac development and function. Circ Res (2011) 1.05