Published in J Periodontal Res on December 01, 2003
Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: a prospective, controlled, randomized study of four hundred and fifty patients. J Bone Joint Surg Am (2002) 5.95
Serum matrix metalloproteinase-8 concentrations are associated with cardiovascular outcome in men. Arterioscler Thromb Vasc Biol (2007) 2.74
The effect of subantimicrobial-dose-doxycycline periodontal therapy on serum biomarkers of systemic inflammation: a randomized, double-masked, placebo-controlled clinical trial. J Am Dent Assoc (2011) 2.20
Matrix metalloproteinase-8 (MMP-8) is the major collagenase in human dentin. Arch Oral Biol (2006) 2.09
Gingival crevicular fluid and serum matrix metalloproteinase-8 and tissue inhibitor of matrix metalloproteinase-1 levels in renal transplant patients undergoing different immunosuppressive therapy. J Clin Periodontol (2008) 2.05
Matrix metalloproteinases: contribution to pathogenesis, diagnosis and treatment of periodontal inflammation. Ann Med (2006) 1.97
Two year randomized controlled trial of etidronate in rheumatoid arthritis: changes in serum aminoterminal telopeptides correlate with radiographic progression of disease. J Rheumatol (2003) 1.77
Toll-like receptor 9 agonists promote cellular invasion by increasing matrix metalloproteinase activity. Mol Cancer Res (2006) 1.69
Systematic review and meta-analysis of the efficacy and safety of existing TNF blocking agents in treatment of rheumatoid arthritis. PLoS One (2012) 1.63
Use of polymerase chain reaction to diagnose tuberculous arthritis from joint tissues and synovial fluid. Arch Pathol Lab Med (2004) 1.63
Operative and nonoperative treatments of medial collateral ligament rupture with early anterior cruciate ligament reconstruction: a prospective randomized study. Am J Sports Med (2006) 1.62
Efficacy and safety of an intraoral electrostimulation device for xerostomia relief: a multicenter, randomized trial. Arthritis Rheum (2011) 1.54
Revision total knee arthroplasty: 1990 through 2002. A review of the Finnish arthroplasty registry. J Bone Joint Surg Am (2006) 1.52
Outcome of prosthesis exchange for infected knee arthroplasty: the effect of treatment approach. Acta Orthop (2009) 1.48
Intraoral electrostimulator for xerostomia relief: a long-term, multicenter, open-label, uncontrolled, clinical trial. Oral Surg Oral Med Oral Pathol Oral Radiol (2012) 1.46
Increased expression and processing of ADAM 12 (meltrin-alpha) in osteolysis associated with aseptic loosening of total hip replacement implants. J Rheumatol (2005) 1.46
Inflammatory immune cell responses and Toll-like receptor expression in synovial tissues in rheumatoid arthritis patients treated with biologics or DMARDs. Clin Rheumatol (2013) 1.42
Corneal innervation and morphology in primary Sjögren's syndrome. Invest Ophthalmol Vis Sci (2003) 1.41
Emdogain in carcinogenesis: a systematic review of in vitro studies. J Oral Sci (2010) 1.41
Incidence of prosthetic joint infections after primary knee arthroplasty. J Arthroplasty (2008) 1.37
Mesenchymal stem cells and cardiac repair. J Cell Mol Med (2008) 1.37
Alterations in corneal sensitivity and nerve morphology in patients with primary Sjögren's syndrome. Exp Eye Res (2008) 1.36
Younger age increases the risk of early prosthesis failure following primary total knee replacement for osteoarthritis. A follow-up study of 32,019 total knee replacements in the Finnish Arthroplasty Register. Acta Orthop (2010) 1.34
Low rate of infected knee replacements in a nationwide series--is it an underestimate? Acta Orthop (2009) 1.32
Generation of biologically active endostatin fragments from human collagen XVIII by distinct matrix metalloproteases. Exp Cell Res (2005) 1.30
Prevention of deep infection in joint replacement surgery. Acta Orthop (2010) 1.28
Matrix metalloproteinases and their tissue inhibitors in aqueous humor of patients with primary open-angle glaucoma, exfoliation syndrome, and exfoliation glaucoma. J Glaucoma (2005) 1.25
Particle disease: biologic mechanisms of periprosthetic osteolysis in total hip arthroplasty. Innate Immun (2012) 1.24
Cartilage repair: past and future--lessons for regenerative medicine. J Cell Mol Med (2009) 1.24
Clinical changes in periodontium during pregnancy and post-partum. J Clin Periodontol (2008) 1.23
Matrix metalloproteinases process the laminin-5 gamma 2-chain and regulate epithelial cell migration. Biochem Biophys Res Commun (2003) 1.23
The effect of subgingival controlled-release delivery of chlorhexidine chip on clinical parameters and matrix metalloproteinase-8 levels in gingival crevicular fluid. J Periodontol (2002) 1.22
Subantimicrobial-dose doxycycline modulates gingival crevicular fluid biomarkers of periodontitis in postmenopausal osteopenic women. J Periodontol (2008) 1.21
Serum MMP-8, -9 and TIMP-1 in sepsis: high serum levels of MMP-8 and TIMP-1 are associated with fatal outcome in a multicentre, prospective cohort study. Hypothetical impact of tetracyclines. Pharmacol Res (2011) 1.21
Relationships between biomarkers of cartilage, bone, synovial metabolism and knee pain provide insights into the origins of pain in early knee osteoarthritis. Arthritis Res Ther (2011) 1.19
Salivary biomarkers of oral health: a cross-sectional study. J Clin Periodontol (2012) 1.19
Alternative materials to improve total hip replacement tribology. Acta Orthop Scand (2003) 1.18
Macrophages-Key cells in the response to wear debris from joint replacements. J Biomed Mater Res A (2013) 1.18
Endostatin inhibits human tongue carcinoma cell invasion and intravasation and blocks the activation of matrix metalloprotease-2, -9, and -13. J Biol Chem (2003) 1.18
Inhibition of the Wnt-β-catenin and Notch signaling pathways sensitizes osteosarcoma cells to chemotherapy. Biochem Biophys Res Commun (2013) 1.18
Bioabsorbable miniplating versus metallic fixation for metacarpal fractures. Clin Orthop Relat Res (2003) 1.17
Gingival crevicular fluid collagenase-2 (MMP-8) test stick for chair-side monitoring of periodontitis. J Periodontal Res (2003) 1.16
Vascular endothelial growth factors C and D and their VEGFR-2 and 3 receptors in blood and lymphatic vessels in healthy and arthritic synovium. J Rheumatol (2002) 1.16
Matrix metalloproteinases -8, -9 and -12 in smokers and patients with stage 0 COPD. Int J Chron Obstruct Pulmon Dis (2007) 1.15
Amyloidosis-recent developments. Semin Arthritis Rheum (2008) 1.14
Salivary biomarkers for detection of systemic diseases. PLoS One (2013) 1.13
Salivary MMP-8, TIMP-1, and ICTP as markers of advanced periodontitis. J Clin Periodontol (2010) 1.12
Total hip replacement in patients eighty years of age and older. J Bone Joint Surg Am (2008) 1.12
Airway obstruction correlates with collagenase-2 (MMP-8) expression and activation in bronchial asthma. Lab Invest (2002) 1.11
Acidic cysteine endoproteinase cathepsin K in the degeneration of the superficial articular hyaline cartilage in osteoarthritis. Arthritis Rheum (2002) 1.11
Use of host- and bacteria-derived salivary markers in detection of periodontitis: a cumulative approach. Dis Markers (2011) 1.08
Complement inhibitor membrane cofactor protein (MCP; CD46) is constitutively shed from cancer cell membranes in vesicles and converted by a metalloproteinase to a functionally active soluble form. Eur J Immunol (2004) 1.07
The microenvironment around total hip replacement prostheses. Clin Orthop Relat Res (2005) 1.07
B-cells and their targeting in rheumatoid arthritis--current concepts and future perspectives. Autoimmun Rev (2011) 1.07
Metalloproteinase inhibition reduces lung injury and improves survival after cecal ligation and puncture in rats. J Surg Res (2003) 1.06
Low serum levels of sex steroids are associated with disease characteristics in primary Sjogren's syndrome; supplementation with dehydroepiandrosterone restores the concentrations. J Clin Endocrinol Metab (2009) 1.06
Activation of matrix metalloproteinase-8 by membrane type 1-MMP and their expression in human tears after photorefractive keratectomy. Invest Ophthalmol Vis Sci (2003) 1.05
Tumor-associated trypsinogen-2 (trypsinogen-2) activates procollagenases (MMP-1, -8, -13) and stromelysin-1 (MMP-3) and degrades type I collagen. Biochemistry (2003) 1.04
Salivary biomarkers of bacterial burden, inflammatory response, and tissue destruction in periodontitis. J Clin Periodontol (2014) 1.03
Bone regeneration: stem cell therapies and clinical studies in orthopaedics and traumatology. J Cell Mol Med (2011) 1.03
Increased expression of toll-like receptors in aseptic loose periprosthetic tissues and septic synovial membranes around total hip implants. J Rheumatol (2009) 1.02
Serum microbial- and host-derived markers of periodontal diseases: a review. Curr Med Chem (2007) 1.02
Inhibition of matrix metalloproteinases by chemically modified tetracyclines in sepsis. Shock (2003) 1.02
Differential Processing of {alpha}- and {beta}-Defensin Precursors by Matrix Metalloproteinase-7 (MMP-7). J Biol Chem (2009) 1.01
Efficacy of sub-antimicrobial dose doxycycline in post-menopausal women: clinical outcomes. J Clin Periodontol (2007) 1.01
Non-antibacterial tetracyclines modulate mediators of periodontitis and atherosclerotic cardiovascular disease: a mechanistic link between local and systemic inflammation. Pharmacol Res (2011) 1.01
Human osteoblasts produce cathepsin K. Bone (2005) 1.00
Toll-like receptors and their adaptors are regulated in macrophages after phagocytosis of lipopolysaccharide-coated titanium particles. J Orthop Res (2011) 0.99
Expression of matrix metalloproteinases-2, -8, -13, -26, and tissue inhibitors of metalloproteinase-1 in human osteosarcoma. Surg Oncol (2010) 0.99
Collagenase-2 (MMP-8) and matrilysin-2 (MMP-26) expression in human wounds of different etiologies. Wound Repair Regen (2007) 0.99
Proteolytic roles of matrix metalloproteinase (MMP)-13 during progression of chronic periodontitis: initial evidence for MMP-13/MMP-9 activation cascade. J Clin Periodontol (2009) 0.99
Bone stress injuries of the lower extremity: a review. Acta Orthop Scand (2002) 0.98
Fluctuating roles of matrix metalloproteinase-9 in oral squamous cell carcinoma. ScientificWorldJournal (2013) 0.97
Local and systemic responses in matrix metalloproteinase 8-deficient mice during Porphyromonas gingivalis-induced periodontitis. Infect Immun (2008) 0.97
Expression of Toll-like receptors and their signaling pathways in rheumatoid synovitis. J Rheumatol (2011) 0.97
Recent advances in understanding molecular mechanisms in the pathogenesis and antibody profile of Sjögren's syndrome. Curr Rheumatol Rep (2003) 0.96
A novel and selective membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor reduces cancer cell motility and tumor growth. Cancer Biol Ther (2009) 0.96
Human mesenchymal stem cell derived osteoblasts degrade organic bone matrix in vitro by matrix metalloproteinases. Matrix Biol (2005) 0.96
Patient reported outcome measures after revision of the infected TKR: comparison of single versus two-stage revision. Knee Surg Sports Traumatol Arthrosc (2012) 0.95
Gelatinase A (MMP-2), collagenase-2 (MMP-8), and laminin-5 gamma2-chain expression in murine inflammatory bowel disease (ulcerative colitis). Dig Dis Sci (2003) 0.95
Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring transforming growth factor beta-activated kinase 1/activating transcription factor 2 signaling: a potential clinical implication for osteoarthritis. Arthritis Rheum (2010) 0.95
Analysis of matrix metalloproteinases, especially MMP-8, in gingival creviclular fluid, mouthrinse and saliva for monitoring periodontal diseases. Periodontol 2000 (2016) 0.95
The effect of adjunctive low-dose doxycycline therapy on clinical parameters and gingival crevicular fluid matrix metalloproteinase-8 levels in chronic periodontitis. J Periodontol (2004) 0.94
Epithelial-mesenchymal transition downregulates laminin alpha5 chain and upregulates laminin alpha4 chain in oral squamous carcinoma cells. Histochem Cell Biol (2008) 0.94
Salivary type I collagen degradation end-products and related matrix metalloproteinases in periodontitis. J Clin Periodontol (2012) 0.94
Chemically modified tetracycline (CMT-8) and estrogen promote wound healing in ovariectomized rats: effects on matrix metalloproteinase-2, membrane type 1 matrix metalloproteinase, and laminin-5 gamma2-chain. Wound Repair Regen (2002) 0.94
Determination of matrix metalloproteinases in human radicular dentin. J Endod (2009) 0.94
Association of gingival crevicular fluid biomarkers during periodontal maintenance with subsequent progressive periodontitis. J Periodontol (2010) 0.93
Basement membrane collagen type IV expression by human mesenchymal stem cells during adipogenic differentiation. J Cell Mol Med (2012) 0.93
Hyaluronate inhibits the interleukin-1beta-induced expression of matrix metalloproteinase (MMP)-1 and MMP-3 in human synovial cells. Tohoku J Exp Med (2004) 0.93
Microbial antigens mediate HLA-B27 diseases via TLRs. J Autoimmun (2009) 0.92
Matrix metalloproteinases and myeloperoxidase in gingival crevicular fluid provide site-specific diagnostic value for chronic periodontitis. J Clin Periodontol (2014) 0.92
Toll-like receptors in the interface membrane around loosening total hip replacement implants. J Biomed Mater Res A (2007) 0.92