Published in Microbiology on January 01, 2004
Agr-mediated dispersal of Staphylococcus aureus biofilms. PLoS Pathog (2008) 3.91
Differential gene expression profiling of Staphylococcus aureus cultivated under biofilm and planktonic conditions. Appl Environ Microbiol (2005) 2.61
A potential new pathway for Staphylococcus aureus dissemination: the silent survival of S. aureus phagocytosed by human monocyte-derived macrophages. PLoS One (2008) 2.12
Association between methicillin susceptibility and biofilm regulation in Staphylococcus aureus isolates from device-related infections. J Clin Microbiol (2007) 1.89
Peptide signaling in the staphylococci. Chem Rev (2010) 1.89
Influence of the two-component system SaeRS on global gene expression in two different Staphylococcus aureus strains. J Bacteriol (2006) 1.76
Factors contributing to the biofilm-deficient phenotype of Staphylococcus aureus sarA mutants. PLoS One (2008) 1.69
Epistatic relationships between sarA and agr in Staphylococcus aureus biofilm formation. PLoS One (2010) 1.60
SarA is an essential positive regulator of Staphylococcus epidermidis biofilm development. J Bacteriol (2005) 1.45
Role of surface protein SasG in biofilm formation by Staphylococcus aureus. J Bacteriol (2010) 1.40
Defining the strain-dependent impact of the Staphylococcal accessory regulator (sarA) on the alpha-toxin phenotype of Staphylococcus aureus. J Bacteriol (2011) 1.36
EsaC substrate for the ESAT-6 secretion pathway and its role in persistent infections of Staphylococcus aureus. Mol Microbiol (2008) 1.30
Staphylococcus aureus biofilms: recent developments in biofilm dispersal. Front Cell Infect Microbiol (2014) 1.27
Transcriptional profiling of target of RNAIII-activating protein, a master regulator of staphylococcal virulence. Infect Immun (2005) 1.24
alphaB-crystallin protects retinal tissue during Staphylococcus aureus-induced endophthalmitis. Infect Immun (2008) 1.19
Identification and characterization of sigma, a novel component of the Staphylococcus aureus stress and virulence responses. PLoS One (2008) 1.19
Cwp84, a surface-associated protein of Clostridium difficile, is a cysteine protease with degrading activity on extracellular matrix proteins. J Bacteriol (2007) 1.17
Investigations into sigmaB-modulated regulatory pathways governing extracellular virulence determinant production in Staphylococcus aureus. J Bacteriol (2006) 1.17
saeRS and sarA act synergistically to repress protease production and promote biofilm formation in Staphylococcus aureus. PLoS One (2012) 1.15
Extracellular proteases are key mediators of Staphylococcus aureus virulence via the global modulation of virulence-determinant stability. Microbiologyopen (2012) 1.13
NsaRS is a cell-envelope-stress-sensing two-component system of Staphylococcus aureus. Microbiology (2011) 1.13
Analysis of bacterial biofilms using NMR-based metabolomics. Future Med Chem (2012) 1.11
Methicillin resistance and the biofilm phenotype in Staphylococcus aureus. Front Cell Infect Microbiol (2015) 1.09
Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis. EMBO J (2012) 1.06
Tricarboxylic acid cycle-dependent attenuation of Staphylococcus aureus in vivo virulence by selective inhibition of amino acid transport. Infect Immun (2009) 1.04
Inactivation of traP has no effect on the agr quorum-sensing system or virulence of Staphylococcus aureus. Infect Immun (2007) 1.04
Staphylococcal proteases aid in evasion of the human complement system. J Innate Immun (2013) 1.02
Staphylococcus aureus Biofilm and Planktonic cultures differentially impact gene expression, mapk phosphorylation, and cytokine production in human keratinocytes. BMC Microbiol (2011) 1.00
Identification of an intracellular M17 family leucine aminopeptidase that is required for virulence in Staphylococcus aureus. Microbes Infect (2012) 0.99
Type I signal peptidase and protein secretion in Staphylococcus epidermidis. J Bacteriol (2010) 0.99
Secreted proteases control autolysin-mediated biofilm growth of Staphylococcus aureus. J Biol Chem (2013) 0.97
The δ subunit of RNA polymerase guides promoter selectivity and virulence in Staphylococcus aureus. Infect Immun (2014) 0.94
The yjeQ gene is required for virulence of Staphylococcus aureus. Infect Immun (2006) 0.93
The AgrD N-terminal leader peptide of Staphylococcus aureus has cytolytic and amyloidogenic properties. Infect Immun (2014) 0.91
The extracytoplasmic function sigma factor σS protects against both intracellular and extracytoplasmic stresses in Staphylococcus aureus. J Bacteriol (2012) 0.91
Cytoplasmic control of premature activation of a secreted protease zymogen: deletion of staphostatin B (SspC) in Staphylococcus aureus 8325-4 yields a profound pleiotropic phenotype. J Bacteriol (2005) 0.90
Staphylococcus aureus seroproteomes discriminate ruminant isolates causing mild or severe mastitis. Vet Res (2011) 0.90
Molecular basis of virulence in Staphylococcus aureus mastitis. PLoS One (2011) 0.89
Inactivation of staphylococcal virulence factors using a light-activated antimicrobial agent. BMC Microbiol (2009) 0.88
Novel inhibitors of Staphylococcus aureus virulence gene expression and biofilm formation. PLoS One (2012) 0.86
Modulation of the Bacillus anthracis secretome by the immune inhibitor A1 protease. J Bacteriol (2013) 0.85
Impact of the functional status of saeRS on in vivo phenotypes of Staphylococcus aureus sarA mutants. Mol Microbiol (2014) 0.83
Passive maternal exposure to environmental microbes selectively modulates the innate defences of chicken egg white by increasing some of its antibacterial activities. BMC Microbiol (2013) 0.82
The Staphylococcus aureus leucine aminopeptidase is localized to the bacterial cytosol and demonstrates a broad substrate range that extends beyond leucine. Biol Chem (2013) 0.81
The AirSR two-component system contributes to Staphylococcus aureus survival in human blood and transcriptionally regulates sspABC operon. Front Microbiol (2015) 0.80
Impact of individual extracellular proteases on Staphylococcus aureus biofilm formation in diverse clinical isolates and their isogenic sarA mutants. Microbiologyopen (2014) 0.80
Hetero- and autoprocessing of the extracellular metalloprotease (Mpr) in Bacillus subtilis. J Bacteriol (2004) 0.80
Hyaluronidase expression and biofilm involvement in Staphylococcus aureus UAMS-1 and its sarA, agr and sarA agr regulatory mutants. Microbiology (2013) 0.79
Efficient co-expression of a recombinant staphopain A and its inhibitor staphostatin A in Escherichia coli. Biochem J (2005) 0.79
Using Quantitative Spectrometry to Understand the Influence of Genetics and Nutritional Perturbations On the Virulence Potential of Staphylococcus aureus. Mol Cell Proteomics (2017) 0.78
Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) isolates of swine origin form robust biofilms. PLoS One (2013) 0.78
Approaches to Dispersing Medical Biofilms. Microorganisms (2017) 0.76
Biochemical and structural characterization of SplD protease from Staphylococcus aureus. PLoS One (2013) 0.76
Galectin-3 is a target for proteases involved in the virulence of Staphylococcus aureus. Infect Immun (2017) 0.75
IL-1β-Induced Protection of Keratinocytes against Staphylococcus aureus-Secreted Proteases Is Mediated by Human β-Defensin 2. J Invest Dermatol (2016) 0.75
Technetium-99m-labeled annexin V imaging for detecting prosthetic joint infection in a rabbit model. J Biomed Res (2014) 0.75
Host-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection. Nat Commun (2017) 0.75
An Update on Clinical Burden, Diagnostic Tools, and Therapeutic Options of Staphylococcus aureus. Infect Dis (Auckl) (2017) 0.75
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J Biol Chem (2003) 9.37
sigmaB modulates virulence determinant expression and stress resistance: characterization of a functional rsbU strain derived from Staphylococcus aureus 8325-4. J Bacteriol (2002) 6.71
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat Immunol (2003) 6.46
New method for typing Staphylococcus aureus strains: multiple-locus variable-number tandem repeat analysis of polymorphism and genetic relationships of clinical isolates. J Clin Microbiol (2003) 2.96
Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan. Gastroenterology (2003) 2.64
Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: implications for autoimmunity in rheumatoid arthritis. Arthritis Rheum (2010) 2.53
Degradation of human antimicrobial peptide LL-37 by Staphylococcus aureus-derived proteinases. Antimicrob Agents Chemother (2004) 2.34
The Staphylococcus aureus surface protein IsdA mediates resistance to innate defenses of human skin. Cell Host Microbe (2007) 2.27
Selective roles for Toll-like receptor (TLR)2 and TLR4 in the regulation of neutrophil activation and life span. J Immunol (2003) 2.18
Comprehensive identification of essential Staphylococcus aureus genes using Transposon-Mediated Differential Hybridisation (TMDH). BMC Genomics (2009) 2.17
A potential new pathway for Staphylococcus aureus dissemination: the silent survival of S. aureus phagocytosed by human monocyte-derived macrophages. PLoS One (2008) 2.12
MntR modulates expression of the PerR regulon and superoxide resistance in Staphylococcus aureus through control of manganese uptake. Mol Microbiol (2002) 2.07
GSK-3beta inhibitors attenuate the organ injury/dysfunction caused by endotoxemia in the rat. Crit Care Med (2005) 2.05
Cell wall peptidoglycan architecture in Bacillus subtilis. Proc Natl Acad Sci U S A (2008) 2.02
Identification of in vivo-expressed antigens of Staphylococcus aureus and their use in vaccinations for protection against nasal carriage. J Infect Dis (2006) 1.99
Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo. J Exp Med (2006) 1.95
Catalase (KatA) and alkyl hydroperoxide reductase (AhpC) have compensatory roles in peroxide stress resistance and are required for survival, persistence, and nasal colonization in Staphylococcus aureus. J Bacteriol (2006) 1.86
Surface adhesins of Staphylococcus aureus. Adv Microb Physiol (2006) 1.77
Manganese: elemental defence for a life with oxygen. Trends Microbiol (2002) 1.75
Insulin reduces the multiple organ injury and dysfunction caused by coadministration of lipopolysaccharide and peptidoglycan independently of blood glucose: role of glycogen synthase kinase-3beta inhibition. Crit Care Med (2006) 1.66
Dichotomy of gingipains action as virulence factors: from cleaving substrates with the precision of a surgeon's knife to a meat chopper-like brutal degradation of proteins. Periodontol 2000 (2010) 1.65
Analysis of Ebh, a 1.1-megadalton cell wall-associated fibronectin-binding protein of Staphylococcus aureus. Infect Immun (2002) 1.63
Analysis of spore cortex lytic enzymes and related proteins in Bacillus subtilis endospore germination. Microbiology (2002) 1.58
Peptidoglycan of Staphylococcus aureus causes inflammation and organ injury in the rat. Crit Care Med (2004) 1.57
Role and regulation of the superoxide dismutases of Staphylococcus aureus. Microbiology (2003) 1.57
Does the importance of the C-terminal residues in the maturation of RgpB from Porphyromonas gingivalis reveal a novel mechanism for protein export in a subgroup of Gram-Negative bacteria? J Bacteriol (2006) 1.56
IsdA of Staphylococcus aureus is a broad spectrum, iron-regulated adhesin. Mol Microbiol (2004) 1.50
Biphasic effect of gingipains from Porphyromonas gingivalis on the human complement system. J Immunol (2007) 1.50
AcmA of Lactococcus lactis is an N-acetylglucosaminidase with an optimal number of LysM domains for proper functioning. FEBS J (2005) 1.45
A novel vertebrate model of Staphylococcus aureus infection reveals phagocyte-dependent resistance of zebrafish to non-host specialized pathogens. Cell Microbiol (2008) 1.45
Role of rubrerythrin in the oxidative stress response of Porphyromonas gingivalis. Mol Microbiol (2002) 1.42
Phagocytosis of Staphylococcus aureus by macrophages exerts cytoprotective effects manifested by the upregulation of antiapoptotic factors. PLoS One (2009) 1.41
Role of a cysteine synthase in Staphylococcus aureus. J Bacteriol (2004) 1.36
Roles of the host oxidative immune response and bacterial antioxidant rubrerythrin during Porphyromonas gingivalis infection. PLoS Pathog (2006) 1.35
Characterization of IsaA and SceD, two putative lytic transglycosylases of Staphylococcus aureus. J Bacteriol (2007) 1.34
A ruthenium(II) polypyridyl complex for direct imaging of DNA structure in living cells. Nat Chem (2009) 1.32
Different walls for rods and balls: the diversity of peptidoglycan. Mol Microbiol (2014) 1.30
Molecular diagnostics for fungal plant pathogens. Pest Manag Sci (2003) 1.28
Sequential autolytic processing activates the zymogen of Arg-gingipain. J Biol Chem (2003) 1.27
Mapping and cloning of late blight resistance genes from Solanum venturii using an interspecific candidate gene approach. Mol Plant Microbe Interact (2009) 1.27
Peptidoglycan architecture can specify division planes in Staphylococcus aureus. Nat Commun (2010) 1.26
On the transcriptional regulation of methicillin resistance: MecI repressor in complex with its operator. J Biol Chem (2004) 1.25
Porphyromonas gingivalis facilitates the development and progression of destructive arthritis through its unique bacterial peptidylarginine deiminase (PAD). PLoS Pathog (2013) 1.22
Peptidoglycan N-acetylglucosamine deacetylases from Bacillus cereus, highly conserved proteins in Bacillus anthracis. J Biol Chem (2005) 1.22
Gingipains from Porphyromonas gingivalis W83 induce cell adhesion molecule cleavage and apoptosis in endothelial cells. Infect Immun (2005) 1.21
The biphasic virulence activities of gingipains: activation and inactivation of host proteins. Curr Protein Pept Sci (2003) 1.21
Characterization of AcmB, an N-acetylglucosaminidase autolysin from Lactococcus lactis. Microbiology (2003) 1.21
The link between periodontal disease and rheumatoid arthritis: an updated review. Curr Rheumatol Rep (2014) 1.20
Identification and characterization of sigma, a novel component of the Staphylococcus aureus stress and virulence responses. PLoS One (2008) 1.19
Heightened immune response to autocitrullinated Porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis. Ann Rheum Dis (2013) 1.18
Staphostatins: an expanding new group of proteinase inhibitors with a unique specificity for the regulation of staphopains, Staphylococcus spp. cysteine proteinases. Mol Microbiol (2003) 1.17
Investigations into sigmaB-modulated regulatory pathways governing extracellular virulence determinant production in Staphylococcus aureus. J Bacteriol (2006) 1.17
Interaction of regulators Mdm2 and Mdmx with transcription factors p53, p63 and p73. Cell Cycle (2010) 1.17
Comparison of gingival crevicular fluid sampling methods in patients with severe chronic periodontitis. J Periodontol (2011) 1.17
Interpain A, a cysteine proteinase from Prevotella intermedia, inhibits complement by degrading complement factor C3. PLoS Pathog (2009) 1.16
Burkholderia Hep_Hag autotransporter (BuHA) proteins elicit a strong antibody response during experimental glanders but not human melioidosis. BMC Microbiol (2007) 1.16
Complementary Tolls in the periodontium: how periodontal bacteria modify complement and Toll-like receptor responses to prevail in the host. Periodontol 2000 (2010) 1.15
Super-resolution microscopy reveals cell wall dynamics and peptidoglycan architecture in ovococcal bacteria. Mol Microbiol (2011) 1.15
High molecular weight gingipains from Porphyromonas gingivalis induce cytokine responses from human macrophage-like cells via a nonproteolytic mechanism. J Innate Immun (2008) 1.15
Binding of complement inhibitor C4b-binding protein contributes to serum resistance of Porphyromonas gingivalis. J Immunol (2008) 1.14
A polysaccharide deacetylase gene (pdaA) is required for germination and for production of muramic delta-lactam residues in the spore cortex of Bacillus subtilis. J Bacteriol (2002) 1.13
NsaRS is a cell-envelope-stress-sensing two-component system of Staphylococcus aureus. Microbiology (2011) 1.13
Hydrolysis of epithelial junctional proteins by Porphyromonas gingivalis gingipains. Infect Immun (2002) 1.12
Drosophila melanogaster as a model host for Staphylococcus aureus infection. Microbiology (2004) 1.11
A new pathway of staphylococcal pathogenesis: apoptosis-like death induced by Staphopain B in human neutrophils and monocytes. J Innate Immun (2008) 1.10
Iron-regulated surface determinant protein A mediates adhesion of Staphylococcus aureus to human corneocyte envelope proteins. Infect Immun (2009) 1.09
Peptidoglycan and lipoteichoic acid in gram-positive bacterial sepsis: receptors, signal transduction, biological effects, and synergism. Shock (2003) 1.09
Verification of a topology model of PorT as an integral outer-membrane protein in Porphyromonas gingivalis. Microbiology (2009) 1.09
Ascorbate oxidase-dependent changes in the redox state of the apoplast modulate gene transcript accumulation leading to modified hormone signaling and orchestration of defense processes in tobacco. Plant Physiol (2006) 1.08
Porphyromonas gingivalis HmuY and HmuR: further characterization of a novel mechanism of heme utilization. Arch Microbiol (2007) 1.08
A novel matrix metalloprotease-like enzyme (karilysin) of the periodontal pathogen Tannerella forsythia ATCC 43037. Biol Chem (2010) 1.08
LytG of Bacillus subtilis is a novel peptidoglycan hydrolase: the major active glucosaminidase. Biochemistry (2003) 1.07
A metalloproteinase karilysin present in the majority of Tannerella forsythia isolates inhibits all pathways of the complement system. J Immunol (2012) 1.07
Three-dimensional structure of MecI. Molecular basis for transcriptional regulation of staphylococcal methicillin resistance. J Biol Chem (2003) 1.07
Expressing a gene encoding wheat oxalate oxidase enhances resistance to Sclerotinia sclerotiorum in oilseed rape (Brassica napus). Planta (2008) 1.06
Invertebrates as animal models for Staphylococcus aureus pathogenesis: a window into host-pathogen interaction. FEMS Immunol Med Microbiol (2005) 1.05
Cell wall elongation mode in Gram-negative bacteria is determined by peptidoglycan architecture. Nat Commun (2013) 1.04
Induction of vascular leakage through release of bradykinin and a novel kinin by cysteine proteinases from Staphylococcus aureus. J Exp Med (2005) 1.04
Gingipains from Porphyromonas gingivalis W83 synergistically disrupt endothelial cell adhesion and can induce caspase-independent apoptosis. Infect Immun (2006) 1.03
A privileged intraphagocyte niche is responsible for disseminated infection of Staphylococcus aureus in a zebrafish model. Cell Microbiol (2012) 1.03
Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis? Arthritis Res Ther (2010) 1.03
Analysis of the peptidoglycan hydrolase complement of Lactococcus lactis: identification of a third N-acetylglucosaminidase, AcmC. Appl Environ Microbiol (2004) 1.03
Multiple essential roles for EzrA in cell division of Staphylococcus aureus. Mol Microbiol (2011) 1.02
Staphylococcal proteases aid in evasion of the human complement system. J Innate Immun (2013) 1.02
Proteolysis of CD14 on human gingival fibroblasts by arginine-specific cysteine proteinases from Porphyromonas gingivalis leading to down-regulation of lipopolysaccharide-induced interleukin-8 production. Infect Immun (2002) 1.02
A new autocatalytic activation mechanism for cysteine proteases revealed by Prevotella intermedia interpain A. J Biol Chem (2007) 1.01
Inactivation of membrane tumor necrosis factor alpha by gingipains from Porphyromonas gingivalis. Infect Immun (2005) 1.01
Staphylococcus aureus-derived staphopain B, a potent cysteine protease activator of plasma chemerin. J Immunol (2007) 1.01
Site-specific O-glycosylation on the MUC2 mucin protein inhibits cleavage by the Porphyromonas gingivalis secreted cysteine protease (RgpB). J Biol Chem (2013) 1.01
IsdA protects Staphylococcus aureus against the bactericidal protease activity of apolactoferrin. Infect Immun (2008) 1.00
Porphyromonas gingivalis induce apoptosis in human gingival epithelial cells through a gingipain-dependent mechanism. BMC Microbiol (2009) 1.00
Identification of an intracellular M17 family leucine aminopeptidase that is required for virulence in Staphylococcus aureus. Microbes Infect (2012) 0.99
The Staphostatin-staphopain complex: a forward binding inhibitor in complex with its target cysteine protease. J Biol Chem (2003) 0.99
Aza-peptide Michael acceptors: a new class of inhibitors specific for caspases and other clan CD cysteine proteases. J Med Chem (2004) 0.99
Role of the hprT-ftsH locus in Staphylococcus aureus. Microbiology (2004) 0.99
Unique structure and stability of HmuY, a novel heme-binding protein of Porphyromonas gingivalis. PLoS Pathog (2009) 0.98
A simple plasmid-based system that allows rapid generation of tightly controlled gene expression in Staphylococcus aureus. Microbiology (2010) 0.98
Staphylococcal cysteine protease staphopain B (SspB) induces rapid engulfment of human neutrophils and monocytes by macrophages. Biol Chem (2009) 0.97