Published in J Gene Med on January 01, 2004
Suppression of non-small cell lung tumor development by the let-7 microRNA family. Proc Natl Acad Sci U S A (2008) 6.89
Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase. Nat Protoc (2009) 4.50
Rapid modelling of cooperating genetic events in cancer through somatic genome editing. Nature (2014) 1.86
Inducing and expanding regulatory T cell populations by foreign antigen. Nat Immunol (2005) 9.91
In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro. Proc Natl Acad Sci U S A (2003) 4.18
Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo. Proc Natl Acad Sci U S A (2004) 4.12
Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation. Immunity (2006) 3.92
Murine leukemia induced by retroviral gene marking. Science (2002) 3.59
Disruption of CREB function in brain leads to neurodegeneration. Nat Genet (2002) 3.54
Elevated maternal C-reactive protein and increased risk of schizophrenia in a national birth cohort. Am J Psychiatry (2014) 2.91
Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice. Gastroenterology (2002) 2.64
Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer. Sci Transl Med (2012) 2.62
T-regulatory cells shift from a protective anti-inflammatory to a cancer-promoting proinflammatory phenotype in polyposis. Cancer Res (2009) 2.43
Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9. Gastroenterology (2009) 2.33
A multicolor panel of novel lentiviral "gene ontology" (LeGO) vectors for functional gene analysis. Mol Ther (2008) 2.31
STAT3 contributes to the mitogenic response of hepatocytes during liver regeneration. J Biol Chem (2002) 2.28
Bile system morphogenesis defects and liver dysfunction upon targeted deletion of HNF1beta. Development (2002) 2.27
Identification of a low-molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice. J Clin Invest (2011) 2.25
Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver. EMBO J (2002) 2.15
Mast cells are an essential hematopoietic component for polyp development. Proc Natl Acad Sci U S A (2007) 2.02
Bone marrow as a priming site for T-cell responses to blood-borne antigen. Nat Med (2003) 2.01
Inhibition of mediodorsal thalamus disrupts thalamofrontal connectivity and cognition. Neuron (2013) 2.01
Direct presentation of antigen by lymph node stromal cells protects against CD8 T-cell-mediated intestinal autoimmunity. Gastroenterology (2008) 2.00
A possible role for the striatum in the pathogenesis of the cognitive symptoms of schizophrenia. Neuron (2010) 1.96
Kinases required in hepatitis C virus entry and replication highlighted by small interference RNA screening. FASEB J (2009) 1.90
Antitumor vaccination of patients with glioblastoma multiforme: a pilot study to assess feasibility, safety, and clinical benefit. J Clin Oncol (2004) 1.84
Liver adenosine monophosphate-activated kinase-alpha2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin. Endocrinology (2006) 1.81
Chronic stress triggers social aversion via glucocorticoid receptor in dopaminoceptive neurons. Science (2013) 1.76
Mast cells in tumor growth: angiogenesis, tissue remodelling and immune-modulation. Biochim Biophys Acta (2009) 1.75
Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma. J Clin Invest (2009) 1.73
RGB marking facilitates multicolor clonal cell tracking. Nat Med (2011) 1.69
Transient overexpression of striatal D2 receptors impairs operant motivation and interval timing. J Neurosci (2007) 1.66
Loss of adenomatous polyposis coli gene function disrupts thymic development. Nat Immunol (2005) 1.66
The MAPK pathway and Egr-1 mediate stress-related behavioral effects of glucocorticoids. Nat Neurosci (2005) 1.66
AML1-ETO inhibits maturation of multiple lymphohematopoietic lineages and induces myeloblast transformation in synergy with ICSBP deficiency. J Exp Med (2002) 1.65
Serological documentation of maternal influenza exposure and bipolar disorder in adult offspring. Am J Psychiatry (2014) 1.64
Genetic evidence for the bidirectional modulation of synaptic plasticity in the prefrontal cortex by D1 receptors. Proc Natl Acad Sci U S A (2004) 1.57
Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth. PLoS One (2008) 1.55
Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy. J Clin Invest (2007) 1.51
Stress and addiction: glucocorticoid receptor in dopaminoceptive neurons facilitates cocaine seeking. Nat Neurosci (2009) 1.51
Making regulatory T cells with defined antigen specificity: role in autoimmunity and cancer. Immunol Rev (2006) 1.50
Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1. J Exp Med (2008) 1.49
Beta-catenin stabilization stalls the transition from double-positive to single-positive stage and predisposes thymocytes to malignant transformation. Blood (2007) 1.48
In colorectal cancer mast cells contribute to systemic regulatory T-cell dysfunction. Proc Natl Acad Sci U S A (2010) 1.47
Foxp3+ CD25+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage. Proc Natl Acad Sci U S A (2006) 1.47
Crosstalk between mast cells and pancreatic cancer cells contributes to pancreatic tumor progression. Clin Cancer Res (2010) 1.46
Miniaturized multichannel near infrared endoscope for mouse imaging. Mol Imaging (2003) 1.45
Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis. Proc Natl Acad Sci U S A (2002) 1.45
Activation of beta -catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias. Proc Natl Acad Sci U S A (2002) 1.44
c-Myc mediates pre-TCR-induced proliferation but not developmental progression. Blood (2006) 1.39
Hepatocyte proliferation during liver regeneration is impaired in mice with liver-specific IGF-1R knockout. FASEB J (2006) 1.39
Host range and cellular tropism of the human exogenous gammaretrovirus XMRV. Virology (2010) 1.38
High frequencies of functional tumor-reactive T cells in bone marrow and blood of pancreatic cancer patients. Cancer Res (2005) 1.35
The glucocorticoid receptor as a potential target to reduce cocaine abuse. J Neurosci (2003) 1.34
Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray. Proc Natl Acad Sci U S A (2008) 1.34
Tumor infiltrating T lymphocytes in colorectal cancer: Tumor-selective activation and cytotoxic activity in situ. Ann Surg (2006) 1.31
Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate. Hepatology (2008) 1.31
High-density lipoproteins reduce the neutralizing effect of hepatitis C virus (HCV)-infected patient antibodies by promoting HCV entry. J Gen Virol (2006) 1.31
Glucocorticoid receptor function in hepatocytes is essential to promote postnatal body growth. Genes Dev (2004) 1.30
Identification of an envelope protein from the FRD family of human endogenous retroviruses (HERV-FRD) conferring infectivity and functional conservation among simians. J Virol (2004) 1.30
Conditional inactivation of androgen receptor gene in the nervous system: effects on male behavioral and neuroendocrine responses. J Neurosci (2009) 1.29
Using conditional mutagenesis to study the brain. Biol Psychiatry (2003) 1.28
Deletion of murine Smn exon 7 directed to liver leads to severe defect of liver development associated with iron overload. Am J Pathol (2004) 1.24
Deficiency of PDK1 in liver results in glucose intolerance, impairment of insulin-regulated gene expression and liver failure. Biochem J (2005) 1.23
A prime-boost strategy using virus-like particles pseudotyped for HCV proteins triggers broadly neutralizing antibodies in macaques. Sci Transl Med (2011) 1.23
Stabilization of beta-catenin induces lesions reminiscent of prostatic intraepithelial neoplasia, but terminal squamous transdifferentiation of other secretory epithelia. Oncogene (2002) 1.22
Inactivation of the glucocorticoid receptor in hepatocytes leads to fasting hypoglycemia and ameliorates hyperglycemia in streptozotocin-induced diabetes mellitus. Mol Endocrinol (2004) 1.21
Combinatorial complexity of 5' alternative acetylcholinesterase transcripts and protein products. J Biol Chem (2004) 1.20
Cathepsin B is involved in the trafficking of TNF-alpha-containing vesicles to the plasma membrane in macrophages. J Immunol (2008) 1.20
Activation of natural killer cells by newcastle disease virus hemagglutinin-neuraminidase. J Virol (2009) 1.20
Expression of Cre recombinase in dopaminoceptive neurons. BMC Neurosci (2007) 1.19
Enrichment of functional CD8 memory T cells specific for MUC1 in bone marrow of patients with multiple myeloma. Blood (2004) 1.19
Palliative Excellence in Alzheimer Care Efforts (PEACE): a program description. J Palliat Med (2003) 1.18
Current status of interleukin-10 and regulatory T-cells in cancer. Curr Opin Oncol (2013) 1.17
Specifically activated memory T cell subsets from cancer patients recognize and reject xenotransplanted autologous tumors. J Clin Invest (2004) 1.16
Adenomatous polyps are driven by microbe-instigated focal inflammation and are controlled by IL-10-producing T cells. Cancer Res (2013) 1.16
Pharmacologic rescue of motivational deficit in an animal model of the negative symptoms of schizophrenia. Biol Psychiatry (2011) 1.16
Predictable and efficient retroviral gene transfer into murine bone marrow repopulating cells using a defined vector dose. Exp Hematol (2003) 1.16
Analysis of dopamine transporter gene expression pattern -- generation of DAT-iCre transgenic mice. FEBS J (2007) 1.16
Neutralizing host responses in hepatitis C virus infection target viral entry at postbinding steps and membrane fusion. Gastroenterology (2008) 1.16
Mesalamine inhibits epithelial beta-catenin activation in chronic ulcerative colitis. Gastroenterology (2009) 1.15
Role of tumor endothelium in CD4+ CD25+ regulatory T cell infiltration of human pancreatic carcinoma. J Natl Cancer Inst (2007) 1.15
Impaired timing precision produced by striatal D2 receptor overexpression is mediated by cognitive and motivational deficits. Behav Neurosci (2009) 1.14
Visualizing the course of antigen-specific CD8 and CD4 T cell responses to a growing tumor. Eur J Immunol (2003) 1.14
When reverse genetics meets physiology: the use of site-specific recombinases in mice. FEBS Lett (2002) 1.13
Mast cell 5-lipoxygenase activity promotes intestinal polyposis in APCDelta468 mice. Cancer Res (2011) 1.13
Tumor cells escape suicide gene therapy by genetic and epigenetic instability. Blood (2004) 1.11
Transient and selective overexpression of D2 receptors in the striatum causes persistent deficits in conditional associative learning. Proc Natl Acad Sci U S A (2008) 1.10
Disabled-2 is transcriptionally regulated by ICSBP and augments macrophage spreading and adhesion. EMBO J (2002) 1.10
Defining the oncogenic function of the TEL/AML1 (ETV6/RUNX1) fusion protein in a mouse model. Oncogene (2005) 1.10
Dissecting the role of glucocorticoids on pancreas development. Diabetes (2004) 1.09
PU.1 level-directed chromatin structure remodeling at the Irf8 gene drives dendritic cell commitment. Cell Rep (2013) 1.09
Expression of RIG-I, IRF3, IFN-beta and IRF7 determines resistance or susceptibility of cells to infection by Newcastle Disease Virus. Int J Oncol (2009) 1.08
Tumor selective replication of Newcastle disease virus: association with defects of tumor cells in antiviral defence. Int J Cancer (2006) 1.08
TNF-related apoptosis-inducing ligand mediates tumoricidal activity of human monocytes stimulated by Newcastle disease virus. J Immunol (2003) 1.08
Aberrant ZNF423 impedes B cell differentiation and is linked to adverse outcome of ETV6-RUNX1 negative B precursor acute lymphoblastic leukemia. J Exp Med (2013) 1.07
Regulation of COX2 expression in mouse mammary tumor cells controls bone metastasis and PGE2-induction of regulatory T cell migration. PLoS One (2012) 1.07
Microglial glucocorticoid receptors play a pivotal role in regulating dopaminergic neurodegeneration in parkinsonism. Proc Natl Acad Sci U S A (2011) 1.07
Intratumoral cytokines and tumor cell biology determine spontaneous breast cancer-specific immune responses and their correlation to prognosis. Cancer Res (2009) 1.07