Published in Proc Natl Acad Sci U S A on February 28, 2008
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell (2009) 11.10
An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell (2009) 10.09
MicroRNAs and cancer: short RNAs go a long way. Cell (2009) 7.25
Lin28 promotes transformation and is associated with advanced human malignancies. Nat Genet (2009) 6.35
Roles for microRNAs in conferring robustness to biological processes. Cell (2012) 6.32
miRNAs in human cancer. J Pathol (2010) 6.02
MicroRNAs in cancer: small molecules with a huge impact. J Clin Oncol (2009) 5.92
Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis. Lancet Oncol (2009) 5.56
Dicer1 functions as a haploinsufficient tumor suppressor. Genes Dev (2009) 5.21
Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy. Nat Rev Cancer (2011) 5.12
A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. Cancer Res (2008) 5.05
miR-19 is a key oncogenic component of mir-17-92. Genes Dev (2009) 4.95
Silencing of microRNA families by seed-targeting tiny LNAs. Nat Genet (2011) 4.81
The Lin28/let-7 axis regulates glucose metabolism. Cell (2011) 4.65
Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase. Nat Protoc (2009) 4.50
The microcosmos of cancer. Nature (2012) 4.50
MicroRNA functions in stress responses. Mol Cell (2010) 4.46
Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation. Proc Natl Acad Sci U S A (2009) 3.76
MicroRNAs in human cancer. Adv Exp Med Biol (2013) 3.19
Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7. EMBO J (2009) 3.11
Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications. Nat Rev Genet (2009) 3.09
MicroRNA expression in squamous cell carcinoma and adenocarcinoma of the esophagus: associations with survival. Clin Cancer Res (2009) 3.03
MicroRNA sponges: progress and possibilities. RNA (2010) 2.96
miR-34 - a microRNA replacement therapy is headed to the clinic. Front Genet (2012) 2.89
Regression of murine lung tumors by the let-7 microRNA. Oncogene (2009) 2.83
The promise of microRNA replacement therapy. Cancer Res (2010) 2.68
MicroRNA biogenesis pathways in cancer. Nat Rev Cancer (2015) 2.67
MicroRNA expression differentiates histology and predicts survival of lung cancer. Clin Cancer Res (2010) 2.48
MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer. Genes Dev (2009) 2.41
MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium. Proc Natl Acad Sci U S A (2009) 2.37
Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. Genes Dev (2010) 2.37
The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation. J Clin Invest (2009) 2.36
MicroRNA microarray identifies Let-7i as a novel biomarker and therapeutic target in human epithelial ovarian cancer. Cancer Res (2008) 2.35
Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis. Nat Struct Mol Biol (2010) 2.30
Regulation of MicroRNA Biogenesis: A miRiad of mechanisms. Cell Commun Signal (2009) 2.27
miRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma. Cancer Res (2012) 2.13
Genome-wide dissection of microRNA functions and cotargeting networks using gene set signatures. Mol Cell (2010) 2.12
An elegant miRror: microRNAs in stem cells, developmental timing and cancer. Chromosoma (2009) 1.99
MicroRNA in lung cancer. Br J Cancer (2010) 1.97
microRNA expression patterns reveal differential expression of target genes with age. PLoS One (2010) 1.92
Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivo. Cell Death Differ (2009) 1.92
MicroRNA let-7: an emerging next-generation cancer therapeutic. Curr Oncol (2010) 1.90
Adult-specific functions of animal microRNAs. Nat Rev Genet (2013) 1.89
MicroRNA expression and clinical outcomes in patients treated with adjuvant chemotherapy after complete resection of non-small cell lung carcinoma. Cancer Res (2010) 1.89
MicroRNA-335 inhibits tumor reinitiation and is silenced through genetic and epigenetic mechanisms in human breast cancer. Genes Dev (2011) 1.85
Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells. Cancer Res (2010) 1.78
Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. Mol Cancer Ther (2011) 1.76
Sequence features associated with microRNA strand selection in humans and flies. BMC Genomics (2009) 1.76
Global microRNA depletion suppresses tumor angiogenesis. Genes Dev (2014) 1.76
Retracted Concomitant suppression of three target genes can explain the impact of a microRNA on metastasis. Genes Dev (2009) 1.74
Rare codons regulate KRas oncogenesis. Curr Biol (2012) 1.74
MicroRNAs as potential biomarkers in human solid tumors. Cancer Lett (2012) 1.73
Augmentation of response to chemotherapy by microRNA-506 through regulation of RAD51 in serous ovarian cancers. J Natl Cancer Inst (2015) 1.68
MicroRNA therapeutics. Gene Ther (2011) 1.61
Exosomal miRNAs: Biological Properties and Therapeutic Potential. Front Genet (2012) 1.60
Metastamirs: a stepping stone towards improved cancer management. Nat Rev Clin Oncol (2010) 1.58
Myc: Maestro of MicroRNAs. Genes Cancer (2010) 1.58
MicroRNA-328 is associated with (non-small) cell lung cancer (NSCLC) brain metastasis and mediates NSCLC migration. Int J Cancer (2011) 1.55
In search of adrenocortical stem and progenitor cells. Endocr Rev (2009) 1.51
Molecular biology of lung cancer: clinical implications. Clin Chest Med (2011) 1.47
MicroRNA 125b inhibition of B cell differentiation in germinal centers. Int Immunol (2010) 1.47
Circular reasoning: microRNAs and cell-cycle control. Trends Biochem Sci (2008) 1.41
Let-7g targets collagen type I alpha2 and inhibits cell migration in hepatocellular carcinoma. J Hepatol (2010) 1.41
SOX2-LIN28/let-7 pathway regulates proliferation and neurogenesis in neural precursors. Proc Natl Acad Sci U S A (2013) 1.39
Identification of microRNAs regulating reprogramming factor LIN28 in embryonic stem cells and cancer cells. J Biol Chem (2010) 1.38
MicroRNA expression in human airway smooth muscle cells: role of miR-25 in regulation of airway smooth muscle phenotype. Am J Respir Cell Mol Biol (2009) 1.36
Loss of let-7 up-regulates EZH2 in prostate cancer consistent with the acquisition of cancer stem cell signatures that are attenuated by BR-DIM. PLoS One (2012) 1.33
microRNA control of cell-cell signaling during development and disease. Cell Cycle (2008) 1.32
Lung cancer cell lines: Useless artifacts or invaluable tools for medical science? Lung Cancer (2010) 1.30
A combinatorial microRNA therapeutics approach to suppressing non-small cell lung cancer. Oncogene (2014) 1.29
Cigarette smoke induces C/EBP-β-mediated activation of miR-31 in normal human respiratory epithelia and lung cancer cells. PLoS One (2010) 1.27
MicroRNAs in ovarian carcinomas. Endocr Relat Cancer (2010) 1.25
MicroRNA delivery by cationic lipoplexes for lung cancer therapy. Mol Pharm (2011) 1.25
KRAS mutation, KRAS-LCS6 polymorphism, and non-small cell lung cancer. Lung Cancer (2009) 1.23
Gankyrin plays an essential role in Ras-induced tumorigenesis through regulation of the RhoA/ROCK pathway in mammalian cells. J Clin Invest (2010) 1.21
Chronic lymphocytic leukemia: interplay between noncoding RNAs and protein-coding genes. Blood (2009) 1.21
Dysregulation of microRNAs in cancer. J Biomed Sci (2012) 1.20
Integrating the MicroRNome into the study of lung disease. Am J Respir Crit Care Med (2008) 1.19
Rapid generation of microRNA sponges for microRNA inhibition. PLoS One (2012) 1.17
Role of MicroRNAs in Hepatocellular Carcinoma. Hepat Mon (2014) 1.17
MicroRNAs in the pathogenesis of Lung Cancer. J Thorac Oncol (2009) 1.17
The role of microRNAs in ovarian cancer. Biomed Res Int (2014) 1.15
Epigenetic modifications in rheumatoid arthritis. Arthritis Res Ther (2008) 1.13
Regulation of microRNA expression and function by nuclear receptor signaling. Cell Biosci (2011) 1.12
The prognostic value of microRNAs varies with patient race/ethnicity and stage of colorectal cancer. Clin Cancer Res (2013) 1.12
siRNA Versus miRNA as Therapeutics for Gene Silencing. Mol Ther Nucleic Acids (2015) 1.12
Update in lung cancer 2008. Am J Respir Crit Care Med (2009) 1.11
let-7 microRNAs induce tamoxifen sensitivity by downregulation of estrogen receptor α signaling in breast cancer. Mol Med (2011) 1.11
The heterochronic microRNA let-7 inhibits cell motility by regulating the genes in the actin cytoskeleton pathway in breast cancer. Mol Cancer Res (2013) 1.11
Prognostic significance of miR-205 in endometrial cancer. PLoS One (2012) 1.10
Therapeutic microRNA strategies in human cancer. AAPS J (2009) 1.10
Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer. Nat Biotechnol (2017) 1.10
Tumor suppressor microRNAs are underrepresented in primary effusion lymphoma and Kaposi sarcoma. Blood (2009) 1.09
MicroRNA-145: a potent tumour suppressor that regulates multiple cellular pathways. J Cell Mol Med (2014) 1.08
MicroRNAs as lung cancer biomarkers. World J Clin Oncol (2014) 1.07
Histone demethylase retinoblastoma binding protein 2 is overexpressed in hepatocellular carcinoma and negatively regulated by hsa-miR-212. PLoS One (2013) 1.07
IMP-1 displays cross-talk with K-Ras and modulates colon cancer cell survival through the novel proapoptotic protein CYFIP2. Cancer Res (2011) 1.07
The let-7 microRNA interfaces extensively with the translation machinery to regulate cell differentiation. Cell Cycle (2008) 1.07
miR-140 suppresses tumor growth and metastasis of non-small cell lung cancer by targeting insulin-like growth factor 1 receptor. PLoS One (2013) 1.07
Cross talk between microRNA and coding cancer genes. Cancer J (2012) 1.06
MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell (2005) 96.87
MicroRNA expression profiles classify human cancers. Nature (2005) 69.12
Prediction of mammalian microRNA targets. Cell (2003) 53.70
A microRNA polycistron as a potential human oncogene. Nature (2005) 40.21
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature (2000) 39.31
RAS is regulated by the let-7 microRNA family. Cell (2005) 30.24
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A (2004) 28.29
Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell (2006) 23.59
ras oncogenes in human cancer: a review. Cancer Res (1989) 22.03
miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci U S A (2005) 21.51
A microRNA component of the p53 tumour suppressor network. Nature (2007) 19.25
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature (2000) 19.15
Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res (2004) 18.86
Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet (2007) 15.46
Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev (2006) 15.20
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol Cell (2007) 14.58
MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat Methods (2007) 13.94
let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell (2007) 13.69
Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science (2007) 12.42
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet (2003) 12.16
High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma. Genes Chromosomes Cancer (2004) 11.79
A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. Cell (2006) 11.01
The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev (2007) 10.15
Transcriptional activation of miR-34a contributes to p53-mediated apoptosis. Mol Cell (2007) 9.51
The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res (2007) 9.32
The differential effects of mutant p53 alleles on advanced murine lung cancer. Cancer Res (2005) 5.93
Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization. Genes Dev (2000) 5.80
High mobility group A2 is a target for miRNA-98 in head and neck squamous cell carcinoma. Mol Cancer (2007) 3.24
Increased expression of high mobility group A proteins in lung cancer. J Pathol (2006) 2.39
A micro-RNA signature associated with race, tumor size, and target gene activity in human uterine leiomyomas. Genes Chromosomes Cancer (2007) 2.35
MicroRNA genes are frequently located near mouse cancer susceptibility loci. Proc Natl Acad Sci U S A (2007) 1.90
High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras. Cancer Res (2006) 1.84
HMGA2 overexpression in non-small cell lung cancer. Mol Carcinog (2007) 1.63
Exogenous control of mammalian gene expression via modulation of translational termination. Nat Med (2006) 1.30
Oncogenic HMGA2: short or small? Genes Dev (2007) 1.28
Prediction and preliminary validation of oncogene regulation by miRNAs. BMC Mol Biol (2007) 1.23
Gene transfer and genetic modification of embryonic stem cells by Cre- and Cre-PR-expressing MESV-based retroviral vectors. J Gene Med (2004) 1.04
MicroRNA expression profiles classify human cancers. Nature (2005) 69.12
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature (2009) 35.48
Specificity of microRNA target selection in translational repression. Genes Dev (2004) 21.14
Predictive identification of exonic splicing enhancers in human genes. Science (2002) 16.86
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell (2008) 16.38
siRNAs can function as miRNAs. Genes Dev (2003) 16.08
Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet (2007) 15.46
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell (2003) 15.43
Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proc Natl Acad Sci U S A (2010) 15.13
Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell (2005) 15.06
MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat Methods (2007) 13.94
Embryonic stem cell-specific MicroRNAs. Dev Cell (2003) 13.05
Restoration of p53 function leads to tumour regression in vivo. Nature (2007) 12.62
Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell (2008) 12.29
A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell (2010) 12.27
c-Myc regulates transcriptional pause release. Cell (2010) 11.64
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1. Nature (2009) 11.46
Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites. Science (2008) 11.33
Divergent transcription from active promoters. Science (2008) 11.03
An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis. Nat Genet (2004) 10.92
Cre-lox-regulated conditional RNA interference from transgenes. Proc Natl Acad Sci U S A (2004) 9.33
Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome. Cell (2004) 8.48
Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects. Cancer Cell (2004) 8.16
Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA (2003) 8.07
Gene silencing in mammals by small interfering RNAs. Nat Rev Genet (2002) 7.80
Killing the messenger: short RNAs that silence gene expression. Nat Rev Mol Cell Biol (2003) 7.38
MicroRNAs and cancer: short RNAs go a long way. Cell (2009) 7.25
Short RNAs repress translation after initiation in mammalian cells. Mol Cell (2006) 6.70
Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells. Cell (2009) 6.55
siRNA-directed inhibition of HIV-1 infection. Nat Med (2002) 6.36
Roles for microRNAs in conferring robustness to biological processes. Cell (2012) 6.32
MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Nat Genet (2004) 6.11
Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry. Nature (2003) 6.01
The differential effects of mutant p53 alleles on advanced murine lung cancer. Cancer Res (2005) 5.93
TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. Science (2005) 5.56
miRNA profiling of naïve, effector and memory CD8 T cells. PLoS One (2007) 5.43
RNA sequence analysis defines Dicer's role in mouse embryonic stem cells. Proc Natl Acad Sci U S A (2007) 5.26
Dicer1 functions as a haploinsufficient tumor suppressor. Genes Dev (2009) 5.21
Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon. Nat Genet (2008) 5.07
Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer. Nat Med (2004) 4.98
Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma. Nature (2009) 4.93
Genetic control by a metabolite binding mRNA. Chem Biol (2002) 4.85
Dynamic regulation of miRNA expression in ordered stages of cellular development. Genes Dev (2007) 4.79
AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer. Cancer Cell (2009) 4.71
p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature (2002) 4.56
Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase. Nat Protoc (2009) 4.50
MicroRNA functions in stress responses. Mol Cell (2010) 4.46
Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family. Cancer Cell (2005) 4.14
Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules. Proc Natl Acad Sci U S A (2006) 4.02
A spatially and temporally restricted mouse model of soft tissue sarcoma. Nat Med (2007) 3.96
The RNAi revolution. Nature (2004) 3.96
Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132. Neuron (2010) 3.96
MicroRNAs can generate thresholds in target gene expression. Nat Genet (2011) 3.90
Expression of tumour-specific antigens underlies cancer immunoediting. Nature (2012) 3.89
Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression. Cell (2008) 3.75
RESCUE-ESE identifies candidate exonic splicing enhancers in vertebrate exons. Nucleic Acids Res (2004) 3.70
RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proc Natl Acad Sci U S A (2003) 3.48
Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease. J Clin Invest (2004) 3.47
Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortium. Cancer Res (2004) 3.43
Context-dependent transformation of adult pancreatic cells by oncogenic K-Ras. Cancer Cell (2009) 3.37
An mRNA structure in bacteria that controls gene expression by binding lysine. Genes Dev (2003) 3.37
Treating metastatic cancer with nanotechnology. Nat Rev Cancer (2011) 3.30
Suppression of lung adenocarcinoma progression by Nkx2-1. Nature (2011) 3.27
Gene silencing using micro-RNA designed hairpins. RNA (2002) 3.21
Cancer modeling in the modern era: progress and challenges. Cell (2002) 3.12
Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7. EMBO J (2009) 3.11
microRNAs: a safeguard against turmoil? Cell (2007) 3.11
Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1. Nature (2002) 3.05
Stage-specific sensitivity to p53 restoration during lung cancer progression. Nature (2010) 3.03
14-3-3sigma controls mitotic translation to facilitate cytokinesis. Nature (2007) 2.98
MicroRNA sponges: progress and possibilities. RNA (2010) 2.96
Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis. Genes Dev (2013) 2.90
Genome-wide identification of Ago2 binding sites from mouse embryonic stem cells with and without mature microRNAs. Nat Struct Mol Biol (2011) 2.85
Single nucleotide polymorphism-based validation of exonic splicing enhancers. PLoS Biol (2004) 2.77
Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells. Proc Natl Acad Sci U S A (2013) 2.75
Single-molecule transcript counting of stem-cell markers in the mouse intestine. Nat Cell Biol (2011) 2.72
Characterization of a highly variable eutherian microRNA gene. RNA (2005) 2.72
Research data in the digital age. Science (2009) 2.65
Promoter directionality is controlled by U1 snRNP and polyadenylation signals. Nature (2013) 2.63
Emerging roles for natural microRNA sponges. Curr Biol (2010) 2.62
Divergent transcription: a new feature of active promoters. Cell Cycle (2009) 2.50
PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells. Cell (2013) 2.38
Poly(ADP-ribose) regulates stress responses and microRNA activity in the cytoplasm. Mol Cell (2011) 2.33
Nuclear factor I/B is an oncogene in small cell lung cancer. Genes Dev (2011) 2.29
Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages. J Virol (2003) 2.26
Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function. Proc Natl Acad Sci U S A (2002) 2.24
Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1. Mol Cell (2003) 2.23
Comparison of siRNA-induced off-target RNA and protein effects. RNA (2007) 2.22
Cell type-specific effects of Rb deletion in the murine retina. Genes Dev (2004) 2.18
Transcriptional silencing of a transgene by RNAi in the soma of C. elegans. Genes Dev (2005) 2.16
A triple helix stabilizes the 3' ends of long noncoding RNAs that lack poly(A) tails. Genes Dev (2012) 2.13
Genome-wide dissection of microRNA functions and cotargeting networks using gene set signatures. Mol Cell (2010) 2.12
p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis. Science (2009) 2.11
RNA polymerase II accumulation in the promoter-proximal region of the dihydrofolate reductase and gamma-actin genes. Mol Cell Biol (2003) 2.07