Published in J Biol Chem on January 19, 2004
Myocyte remodeling in response to hypertrophic stimuli requires nucleocytoplasmic shuttling of muscle LIM protein. J Mol Cell Cardiol (2009) 1.04
Update on staphylococcal superantigen-induced signaling pathways and therapeutic interventions. Toxins (Basel) (2013) 1.03
Suppression of acute lung inflammation by intracellular peptide delivery of a nuclear import inhibitor. Mol Ther (2009) 1.03
Intracellular delivery of a cell-penetrating SOCS1 that targets IFN-gamma signaling. Sci Signal (2009) 0.90
In vivo islet protection by a nuclear import inhibitor in a mouse model of type 1 diabetes. PLoS One (2010) 0.88
Therapeutic down-modulators of staphylococcal superantigen-induced inflammation and toxic shock. Toxins (Basel) (2010) 0.85
A nuclear import inhibitory peptide ameliorates the severity of cholecystokinin-induced acute pancreatitis. World J Gastroenterol (2005) 0.83
Antitumor activity of cell-permeable RUNX3 protein in gastric cancer cells. Clin Cancer Res (2012) 0.82
Antitumor activity of cell-permeable p18(INK4c) with enhanced membrane and tissue penetration. Mol Ther (2012) 0.81
Lethality in a murine model of pulmonary anthrax is reduced by combining nuclear transport modifier with antimicrobial therapy. PLoS One (2012) 0.81
Partial somatic to stem cell transformations induced by cell-permeable reprogramming factors. Sci Rep (2014) 0.80
PI3K/Akt/mTOR, a pathway less recognized for staphylococcal superantigen-induced toxicity. Toxins (Basel) (2012) 0.79
Cell-permeable parkin proteins suppress Parkinson disease-associated phenotypes in cultured cells and animals. PLoS One (2014) 0.75
Survival, bacterial clearance and thrombocytopenia are improved in polymicrobial sepsis by targeting nuclear transport shuttles. PLoS One (2017) 0.75
Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression. Nat Biotechnol (2011) 6.54
The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways. Nat Immunol (2007) 2.91
Selective cyclooxygenase-1 and -2 inhibitors each increase allergic inflammation and airway hyperresponsiveness in mice. Am J Respir Crit Care Med (2002) 2.17
Characterization of KRAS rearrangements in metastatic prostate cancer. Cancer Discov (2011) 2.02
Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis. Nat Med (2005) 1.88
Granulocyte-macrophage colony-stimulating factor regulates effector differentiation of invariant natural killer T cells during thymic ontogeny. Immunity (2006) 1.82
Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin. Am J Pathol (2005) 1.76
Interactive sites in the MyD88 Toll/interleukin (IL) 1 receptor domain responsible for coupling to the IL1beta signaling pathway. J Biol Chem (2005) 1.70
Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer. Genome Res (2011) 1.63
Molecular analysis of sarcoidosis tissues for mycobacterium species DNA. Emerg Infect Dis (2002) 1.59
Differential immune responses and pulmonary pathophysiology are induced by two different strains of respiratory syncytial virus. Am J Pathol (2006) 1.55
Respiratory syncytial virus infection in the absence of STAT 1 results in airway dysfunction, airway mucus, and augmented IL-17 levels. J Allergy Clin Immunol (2005) 1.52
Relation of parity with common carotid intima-media thickness among women of the Study of Health in Pomerania. Stroke (2005) 1.52
Nuclear import of proinflammatory transcription factors is required for massive liver apoptosis induced by bacterial lipopolysaccharide. J Biol Chem (2004) 1.49
Respiratory syncytial virus in allergic lung inflammation increases Muc5ac and gob-5. Am J Respir Crit Care Med (2004) 1.27
Relation of self-reported sleep duration with carotid intima-media thickness in a general population sample. Atherosclerosis (2007) 1.19
Positive regulation of IkappaB kinase signaling by protein serine/threonine phosphatase 2A. J Biol Chem (2005) 1.13
Cutting edge: K63-linked polyubiquitination of NEMO modulates TLR signaling and inflammation in vivo. J Immunol (2008) 1.11
Signal-induced ubiquitination of I kappaB Kinase-beta. J Biol Chem (2003) 1.09
The discovery of the potent aurora inhibitor MK-0457 (VX-680). Bioorg Med Chem Lett (2009) 1.04
Suppression of acute lung inflammation by intracellular peptide delivery of a nuclear import inhibitor. Mol Ther (2009) 1.03
IkappaB kinase subunits alpha and gamma are required for activation of NF-kappaB and induction of apoptosis by mammalian reovirus. J Virol (2006) 1.02
Receptor/transporter-independent targeting of functional peptides across the plasma membrane. J Biol Chem (2003) 1.00
Identification of an NF-kappaB-dependent gene network in cells infected by mammalian reovirus. J Virol (2006) 0.99
In vivo identification of inducible phosphoacceptors in the IKKgamma/NEMO subunit of human IkappaB kinase. J Biol Chem (2003) 0.98
Cyclooxygenase inhibition augments allergic inflammation through CD4-dependent, STAT6-independent mechanisms. J Immunol (2005) 0.97
Signaling through the prostaglandin I2 receptor IP protects against respiratory syncytial virus-induced illness. J Virol (2004) 0.96
Changes in retail tobacco promotions in a cohort of stores before, during, and after a tobacco product display ban. Am J Public Health (2011) 0.95
Site-specific monoubiquitination of IkappaB kinase IKKbeta regulates its phosphorylation and persistent activation. J Biol Chem (2005) 0.94
STAT1 negatively regulates lung basophil IL-4 expression induced by respiratory syncytial virus infection. J Immunol (2009) 0.94
Gender differences in the relation between number of teeth and systolic blood pressure. J Hypertens (2006) 0.93
Association between high serum ferritin levels and carotid atherosclerosis in the study of health in Pomerania (SHIP). Stroke (2004) 0.91
Intracellular delivery of a cell-penetrating SOCS1 that targets IFN-gamma signaling. Sci Signal (2009) 0.90
In vivo islet protection by a nuclear import inhibitor in a mouse model of type 1 diabetes. PLoS One (2010) 0.88
Fractalkine and CX3CR1 mediate leukocyte capture by endothelium in response to Shiga toxin. J Immunol (2008) 0.87
Deficiency of gp91phox inhibits allergic airway inflammation. Am J Respir Cell Mol Biol (2013) 0.87
RNA global alignment in the joint sequence-structure space using elastic shape analysis. Nucleic Acids Res (2013) 0.86
Lateral frontal sinus access in endoscopic skull-base surgery. Int Forum Allergy Rhinol (2011) 0.86
Targeting nuclear import shuttles, importins/karyopherins alpha by a peptide mimicking the NFκB1/p50 nuclear localization sequence. J Am Heart Assoc (2013) 0.85
Combination of electrocardiographic and echocardiographic information identifies individuals prone to a progressive increase in left ventricular mass over 5 years. J Hypertens (2009) 0.84
PGI synthase overexpression protects against bleomycin-induced mortality and is associated with increased Nqo 1 expression. Am J Physiol Lung Cell Mol Physiol (2011) 0.84
Extended anti-inflammatory action of a degradation-resistant mutant of cell-penetrating suppressor of cytokine signaling 3. J Biol Chem (2010) 0.83
Lethality in a murine model of pulmonary anthrax is reduced by combining nuclear transport modifier with antimicrobial therapy. PLoS One (2012) 0.81
Nuclear transport modulation reduces hypercholesterolemia, atherosclerosis, and fatty liver. J Am Heart Assoc (2013) 0.81
The innate immunity adaptor SARM translocates to the nucleus to stabilize lamins and prevent DNA fragmentation in response to pro-apoptotic signaling. PLoS One (2013) 0.81
Cutting edge: the "death" adaptor CRADD/RAIDD targets BCL10 and suppresses agonist-induced cytokine expression in T lymphocytes. J Immunol (2012) 0.80
Transcriptional signaling pathways inversely regulated in Alzheimer's disease and glioblastoma multiform. Sci Rep (2013) 0.80
Low serum magnesium concentrations predict increase in left ventricular mass over 5 years independently of common cardiovascular risk factors. Atherosclerosis (2010) 0.80
Factors influencing farmers' willingness to participate in the conversion of cultivated land to wetland program in Sanjiang National Nature Reserve, China. Environ Manage (2010) 0.79
Outcomes of recurrent head and neck cutaneous squamous cell carcinoma. J Skin Cancer (2011) 0.78
Putative association between anti-Borrelia IgG and autoimmune thyroid disease? Thyroid (2005) 0.77
Theodore E. Woodward Award: The devastating backlash of a dread disease: poliomyelitis. Trans Am Clin Climatol Assoc (2005) 0.75
Challenges of treating a 466-kilogram man with acute kidney injury. Am J Kidney Dis (2008) 0.75
Serum thyrotropin levels predict all-cause and circulatory mortality in patients with invasively treated coronary artery disease. Int J Cardiol (2008) 0.75
Twenty-first century pathology sign-out. Clin Lab Med (2012) 0.75