Published in Semin Immunol on February 01, 2004
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The Fas-associated death domain protein is required in apoptosis and TLR-induced proliferative responses in B cells. J Immunol (2006) 1.52
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Surfactant protein D is expressed and modulates inflammatory responses in human coronary artery smooth muscle cells. Am J Physiol Heart Circ Physiol (2008) 1.47
Topical TLR7 agonist imiquimod can induce immune-mediated rejection of skin metastases in patients with breast cancer. Clin Cancer Res (2012) 1.46
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Toll-like receptor 4 mediates lipopolysaccharide-induced muscle catabolism via coordinate activation of ubiquitin-proteasome and autophagy-lysosome pathways. FASEB J (2010) 1.46
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Staphylococcus aureus-induced corneal inflammation is dependent on Toll-like receptor 2 and myeloid differentiation factor 88. Infect Immun (2006) 1.43
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ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stability. Mol Cell Biol (2004) 1.28
A distinct Toll-like receptor repertoire in human tonsillar B cells, directly activated by PamCSK, R-837 and CpG-2006 stimulation. Immunology (2006) 1.27
NADPH oxidase-dependent reactive oxygen species mediate amplified TLR4 signaling and sepsis-induced mortality in Nrf2-deficient mice. J Immunol (2010) 1.26
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A genome-wide association analysis reveals 1p31 and 2p13.3 as susceptibility loci for Kawasaki disease. Hum Genet (2011) 1.19
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TLR2-dependent selective autophagy regulates NF-κB lysosomal degradation in hepatoma-derived M2 macrophage differentiation. Cell Death Differ (2012) 1.17
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Herpes simplex type I (HSV-1) infection of the nervous system: is an immune response a good thing? J Neuroimmunol (2009) 1.16
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Central role for MyD88 in the responses of microglia to pathogen-associated molecular patterns. J Immunol (2006) 1.15
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The Toll-like receptor 4 agonist monophosphoryl lipid a augments innate host resistance to systemic bacterial infection. Infect Immun (2011) 1.13
NOX enzymes and Toll-like receptor signaling. Semin Immunopathol (2008) 1.13
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The functional role of microRNAs in alcoholic liver injury. J Cell Mol Med (2014) 1.13
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol (2004) 26.12
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Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature (2006) 9.77
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Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron. Nature (2004) 9.40
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TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature (2007) 8.87
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A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA. Nat Immunol (2005) 7.94
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta. Nat Immunol (2008) 7.87
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Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages. Nat Cell Biol (2009) 7.35
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Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nat Med (2007) 7.25
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Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury. Cell (2008) 6.37
Essential function for the kinase TAK1 in innate and adaptive immune responses. Nat Immunol (2005) 6.13
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Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus. J Exp Med (2005) 4.92
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Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans. Nat Immunol (2006) 4.37
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Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay. Nature (2009) 3.50
Krüppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation. Cell Metab (2005) 3.49
Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney. J Clin Invest (2005) 3.48
Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression. Cancer Cell (2011) 3.47
STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury. J Neurosci (2008) 3.44
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CpG directly induces T-bet expression and inhibits IgG1 and IgE switching in B cells. Nat Immunol (2003) 3.41
SOCS-1 participates in negative regulation of LPS responses. Immunity (2002) 3.39