Published in J Pharmacol Exp Ther on February 04, 2004
Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents. J Clin Invest (2008) 2.20
Alcohol and airways function in health and disease. Alcohol (2007) 1.53
Hydrogen sulfide causes vanilloid receptor 1-mediated neurogenic inflammation in the airways. Br J Pharmacol (2005) 1.34
TRPV1: on the road to pain relief. Curr Mol Pharmacol (2008) 1.26
Analysing the causes of chronic cough: relation to diesel exhaust, ozone, nitrogen oxides, sulphur oxides and other environmental factors. J Occup Med Toxicol (2006) 1.06
Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells. J Pharmacol Exp Ther (2007) 1.01
A role for transient receptor potential vanilloid 4 in tonicity-induced neurogenic inflammation. Br J Pharmacol (2010) 0.99
Recent advances in intravesical drug/gene delivery. Mol Pharm (2006) 0.97
Chronic cough due to occupational factors. J Occup Med Toxicol (2006) 0.96
Alcohol feeding blocks methacholine-induced airway responsiveness in mice. Am J Physiol Lung Cell Mol Physiol (2008) 0.95
TRPV1: a target for next generation analgesics. Curr Neuropharmacol (2008) 0.95
Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain. Brain Behav Immun (2013) 0.92
Alcohol reduces airway hyperresponsiveness (AHR) and allergic airway inflammation in mice. Am J Physiol Lung Cell Mol Physiol (2011) 0.91
Pharmacological characterisation of capsaicin-induced relaxations in human and porcine isolated arteries. Naunyn Schmiedebergs Arch Pharmacol (2007) 0.91
Reduced oral ethanol avoidance in mice lacking transient receptor potential channel vanilloid receptor 1. Behav Genet (2008) 0.90
Capsaicin-induced changes in LTP in the lateral amygdala are mediated by TRPV1. PLoS One (2011) 0.89
Anatomical and functional characterization of a duodeno-pancreatic neural reflex that can induce acute pancreatitis. Am J Physiol Gastrointest Liver Physiol (2013) 0.85
Analysis and evaluation of environmental tobacco smoke exposure as a risk factor for chronic cough. Cough (2007) 0.79
Airway reflux, cough and respiratory disease. Ther Adv Chronic Dis (2011) 0.76
Response of smooth bronchial musculature in bronchoconstrictor substances in newborn with lung atelectasis at the respiratory distress syndrome (RDS). Med Arch (2014) 0.75
Mediating Role of TRPV1 Ion Channels in the Co-exposure to PM2.5 and Formaldehyde of Balb/c Mice Asthma Model. Sci Rep (2017) 0.75
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1. Proc Natl Acad Sci U S A (2007) 4.10
Identity-by-descent filtering of exome sequence data identifies PIGV mutations in hyperphosphatasia mental retardation syndrome. Nat Genet (2010) 3.60
Effect of β-blockers and other antihypertensive drugs on the risk of melanoma recurrence and death. Mayo Clin Proc (2013) 3.59
An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors. Proc Natl Acad Sci U S A (2002) 3.16
Mast cell-dependent excitation of visceral-nociceptive sensory neurons in irritable bowel syndrome. Gastroenterology (2007) 2.63
Treatment with β-blockers and reduced disease progression in patients with thick melanoma. Arch Intern Med (2011) 2.53
Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia. J Neurosci (2004) 2.42
Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice. J Physiol (2006) 2.34
Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents. J Clin Invest (2008) 2.20
Prostate growth and prevalence of prostate diseases in early onset spinal cord injuries. Eur Urol (2008) 2.15
Somatic mutation profiles of MSI and MSS colorectal cancer identified by whole exome next generation sequencing and bioinformatics analysis. PLoS One (2010) 2.10
Protease-activated receptor 2 mediates eosinophil infiltration and hyperreactivity in allergic inflammation of the airway. J Immunol (2002) 1.99
The toxicity of cadmium and resulting hazards for human health. J Occup Med Toxicol (2006) 1.72
Institutional operating figures in basic and applied sciences: scientometric analysis of quantitative output benchmarking. Health Res Policy Syst (2008) 1.70
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system. Brain (2011) 1.70
Hydrogen sulfide is a novel prosecretory neuromodulator in the Guinea-pig and human colon. Gastroenterology (2006) 1.66
Increased expression of transient receptor potential vanilloid-1 in airway nerves of chronic cough. Am J Respir Crit Care Med (2004) 1.66
Pan-neurotrophin receptor p75 contributes to neuronal hyperreactivity and airway inflammation in a murine model of experimental asthma. Am J Respir Cell Mol Biol (2003) 1.65
Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1. Proc Natl Acad Sci U S A (2008) 1.59
Neuronal plasticity of the "brain-skin connection": stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways. J Mol Med (Berl) (2007) 1.58
Pungent general anesthetics activate transient receptor potential-A1 to produce hyperalgesia and neurogenic bronchoconstriction. Anesthesiology (2010) 1.54
The TRPA1 channel in migraine mechanism and treatment. Br J Pharmacol (2014) 1.50
Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels. EMBO J (2005) 1.48
Down-regulated in adenoma mediates apical Cl-/HCO3- exchange in rabbit, rat, and human duodenum. Gastroenterology (2002) 1.47
Evidence for differential expression of Notch receptors and their ligands in melanocytic nevi and cutaneous malignant melanoma. Mod Pathol (2006) 1.46
Tachykinins and their receptors: contributions to physiological control and the mechanisms of disease. Physiol Rev (2014) 1.40
Alpha,beta-unsaturated aldehydes in cigarette smoke release inflammatory mediators from human macrophages. Am J Respir Cell Mol Biol (2007) 1.40
Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation. Pain (2011) 1.35
TRPV1: a therapeutic target for novel analgesic drugs? Trends Mol Med (2006) 1.34
Hydrogen sulfide causes vanilloid receptor 1-mediated neurogenic inflammation in the airways. Br J Pharmacol (2005) 1.34
Capsaicin-sensitive and -insensitive vagal bronchopulmonary C-fibres in the mouse. J Physiol (2003) 1.33
The TRPA1 channel in inflammatory and neuropathic pain and migraine. Rev Physiol Biochem Pharmacol (2014) 1.29
Inter-disease comparison of research quantity and quality: bronchial asthma and chronic obstructive pulmonary disease. J Asthma (2009) 1.28
The TGR5 receptor mediates bile acid-induced itch and analgesia. J Clin Invest (2013) 1.27
Reduced cardiocirculatory complications with unrestrictive visiting policy in an intensive care unit: results from a pilot, randomized trial. Circulation (2006) 1.24
Nanomedicine for respiratory diseases. Eur J Pharmacol (2006) 1.23
Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation. PLoS One (2012) 1.23
Presynaptic enzymatic neurotoxins. J Neurochem (2006) 1.23
Adherence to antihypertensive medications and health outcomes among newly treated hypertensive patients. Clinicoecon Outcomes Res (2011) 1.22
Stress inhibits hair growth in mice by induction of premature catagen development and deleterious perifollicular inflammatory events via neuropeptide substance P-dependent pathways. Am J Pathol (2003) 1.22
Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation. Cancer Discov (2012) 1.21
Neurogenic responses mediated by vanilloid receptor-1 (TRPV1) are blocked by the high affinity antagonist, iodo-resiniferatoxin. Br J Pharmacol (2003) 1.20
Analysis of research output parameters: density equalizing mapping and citation trend analysis. BMC Health Serv Res (2009) 1.19
Smoking prevention in school students: positive effects of a hospital-based intervention. Dtsch Arztebl Int (2012) 1.17
Spatial interactions between dendritic cells and sensory nerves in allergic airway inflammation. Am J Respir Cell Mol Biol (2007) 1.17
Predictive validity of measures of comorbidity in older community dwellers: the Insufficienza Cardiaca negli Anziani Residenti a Dicomano Study. J Am Geriatr Soc (2006) 1.15
Antioxidant properties of a novel phycocyanin extract from the blue-green alga Aphanizomenon flos-aquae. Life Sci (2004) 1.15
Desacyl ghrelin inhibits the orexigenic effect of peripherally injected ghrelin in rats. Peptides (2008) 1.14
Physicians' working conditions and job satisfaction: does hospital ownership in Germany make a difference? BMC Health Serv Res (2009) 1.14
General and visceral surgery practice in German hospitals: a real-time work analysis on surgeons' work flow. Langenbecks Arch Surg (2009) 1.13
Expression of capsaicin receptor immunoreactivity in human peripheral nervous system and in painful neuropathies. J Peripher Nerv Syst (2006) 1.12
Brain-derived neurotrophic factor (BDNF) contributes to neuronal dysfunction in a model of allergic airway inflammation. Br J Pharmacol (2004) 1.12
Distribution of respiratory mucin proteins in human nasal mucosa. Laryngoscope (2003) 1.11
Expression of protease-activated receptors 1 and 2 in melanocytic nevi and malignant melanoma. Hum Pathol (2005) 1.10
Protease-activated receptor-2 activation exaggerates TRPV1-mediated cough in guinea pigs. J Appl Physiol (1985) (2006) 1.08
Ionizing radiation triggers chromatin-bound kin17 complex formation in human cells. J Biol Chem (2002) 1.07
Cognitive-enhancing substance use at German universities: frequency, reasons and gender differences. Wien Med Wochenschr (2012) 1.07
Influenza: a scientometric and density-equalizing analysis. BMC Infect Dis (2013) 1.06
Analysing the causes of chronic cough: relation to diesel exhaust, ozone, nitrogen oxides, sulphur oxides and other environmental factors. J Occup Med Toxicol (2006) 1.06
SMAD-signaling in chronic obstructive pulmonary disease: transcriptional down-regulation of inhibitory SMAD 6 and 7 by cigarette smoke. Biol Chem (2004) 1.05
Protease-activated receptor-2 stimulates angiogenesis and accelerates hemodynamic recovery in a mouse model of hindlimb ischemia. Circ Res (2002) 1.05
Development and evaluation of a computer-based medical work assessment programme. J Occup Med Toxicol (2008) 1.05
Novel concepts of neuropeptide-based drug therapy: vasoactive intestinal polypeptide and its receptors. Eur J Pharmacol (2006) 1.05
Yellow fever disease: density equalizing mapping and gender analysis of international research output. Parasit Vectors (2013) 1.04
Mediators of asthma: nitric oxide. Pulm Pharmacol Ther (2002) 1.04
In vitro models to study hepatotoxicity. Toxicol Pathol (2002) 1.03
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents. J Med Chem (2010) 1.03
Activation of TRPA1 on dural afferents: a potential mechanism of headache pain. Pain (2012) 1.03
CGRP receptors in the control of pain and inflammation. Curr Opin Pharmacol (2009) 1.03
Pediatricians' working conditions in German hospitals: a real-time task analysis. Eur J Pediatr (2009) 1.02
Air pollution research: visualization of research activity using density-equalizing mapping and scientometric benchmarking procedures. J Occup Med Toxicol (2010) 1.02
Oxidative stress and antioxidant status in patients undergoing prolonged exposure to hyperbaric oxygen. Clin Biochem (2004) 1.02
Development of the first ultra-potent "capsaicinoid" agonist at transient receptor potential vanilloid type 1 (TRPV1) channels and its therapeutic potential. J Pharmacol Exp Ther (2004) 1.01
TRPA1 and TRPV4 mediate paclitaxel-induced peripheral neuropathy in mice via a glutathione-sensitive mechanism. Pflugers Arch (2012) 1.01