Published in Biochemistry on February 24, 2004
Bacterial chemoreceptors: high-performance signaling in networked arrays. Trends Biochem Sci (2007) 5.28
Structure of the conserved HAMP domain in an intact, membrane-bound chemoreceptor: a disulfide mapping study. Biochemistry (2007) 1.80
Physical responses of bacterial chemoreceptors. J Mol Biol (2006) 1.67
Structure of concatenated HAMP domains provides a mechanism for signal transduction. Structure (2010) 1.58
Use of site-directed cysteine and disulfide chemistry to probe protein structure and dynamics: applications to soluble and transmembrane receptors of bacterial chemotaxis. Methods Enzymol (2007) 1.58
Engineered socket study of signaling through a four-helix bundle: evidence for a yin-yang mechanism in the kinase control module of the aspartate receptor. Biochemistry (2009) 1.51
Adaptation mechanism of the aspartate receptor: electrostatics of the adaptation subdomain play a key role in modulating kinase activity. Biochemistry (2005) 1.51
The core signaling proteins of bacterial chemotaxis assemble to form an ultrastable complex. Biochemistry (2009) 1.46
Conserved glycine residues in the cytoplasmic domain of the aspartate receptor play essential roles in kinase coupling and on-off switching. Biochemistry (2005) 1.44
The structure of a soluble chemoreceptor suggests a mechanism for propagating conformational signals. Biochemistry (2009) 1.18
Evidence that the adaptation region of the aspartate receptor is a dynamic four-helix bundle: cysteine and disulfide scanning studies. Biochemistry (2005) 1.15
Signaling and sensory adaptation in Escherichia coli chemoreceptors: 2015 update. Trends Microbiol (2015) 1.10
Role of predicted transmembrane domains for type III translocation, pore formation, and signaling by the Yersinia pseudotuberculosis YopB protein. Infect Immun (2005) 1.09
The piston rises again. Structure (2009) 1.04
Structure of bacterial cytoplasmic chemoreceptor arrays and implications for chemotactic signaling. Elife (2014) 1.03
Topology and boundaries of the aerotaxis receptor Aer in the membrane of Escherichia coli. J Bacteriol (2006) 1.03
Transmembrane helix dynamics of bacterial chemoreceptors supports a piston model of signalling. PLoS Comput Biol (2011) 1.02
Transmembrane signaling of chemotaxis receptor tar: insights from molecular dynamics simulation studies. Biophys J (2011) 1.00
Mutational analysis of the control cable that mediates transmembrane signaling in the Escherichia coli serine chemoreceptor. J Bacteriol (2011) 0.98
The control of transmembrane helix transverse position in membranes by hydrophilic residues. J Mol Biol (2007) 0.98
New insights into bacterial chemoreceptor array structure and assembly from electron cryotomography. Biochemistry (2014) 0.94
Defining a key receptor-CheA kinase contact and elucidating its function in the membrane-bound bacterial chemosensory array: a disulfide mapping and TAM-IDS Study. Biochemistry (2013) 0.94
Mechanism of bacterial signal transduction revealed by molecular dynamics of Tsr dimers and trimers of dimers in lipid vesicles. PLoS Comput Biol (2012) 0.92
Polar chemoreceptor clustering by coupled trimers of dimers. Biophys J (2009) 0.90
Isolated bacterial chemosensory array possesses quasi- and ultrastable components: functional links between array stability, cooperativity, and order. Biochemistry (2012) 0.89
Influence of membrane lipid composition on a transmembrane bacterial chemoreceptor. J Biol Chem (2012) 0.87
Site-specific and synergistic stimulation of methylation on the bacterial chemotaxis receptor Tsr by serine and CheW. BMC Microbiol (2005) 0.86
The PTI1-like kinase ZmPti1a from maize (Zea mays L.) co-localizes with callose at the plasma membrane of pollen and facilitates a competitive advantage to the male gametophyte. BMC Plant Biol (2006) 0.86
Structure, function, and on-off switching of a core unit contact between CheA kinase and CheW adaptor protein in the bacterial chemosensory array: A disulfide mapping and mutagenesis study. Biochemistry (2013) 0.84
The extension of the fourth transmembrane helix of the sensor kinase KdpD of Escherichia coli is involved in sensing. J Bacteriol (2007) 0.83
Increasing and decreasing the ultrastability of bacterial chemotaxis core signaling complexes by modifying protein-protein contacts. Biochemistry (2014) 0.81
The role of membrane-mediated interactions in the assembly and architecture of chemoreceptor lattices. PLoS Comput Biol (2014) 0.81
A Trigger Residue for Transmembrane Signaling in the Escherichia coli Serine Chemoreceptor. J Bacteriol (2015) 0.80
Structural characterization of AS1-membrane interactions from a subset of HAMP domains. Biochim Biophys Acta (2011) 0.78
Differential repositioning of the second transmembrane helices from E. coli Tar and EnvZ upon moving the flanking aromatic residues. Biochim Biophys Acta (2014) 0.77
Importance of indole N-H hydrogen bonding in the organization and dynamics of gramicidin channels. Biochim Biophys Acta (2013) 0.77
Membrane organization and dynamics of "inner pair" and "outer pair" tryptophan residues in gramicidin channels. J Phys Chem B (2012) 0.77
Dynamics of a membrane-bound tryptophan analog in environments of varying hydration: a fluorescence approach. Eur Biophys J (2005) 0.76
Aromaticity at the water-hydrocarbon core interface of the membrane: consequences on the nicotinic acetylcholine receptor. Channels (Austin) (2008) 0.75
Employing aromatic tuning to modulate output from two-component signaling circuits. J Biol Eng (2015) 0.75
The Single Transmembrane Segment of Minimal Sensor DesK Senses Temperature via a Membrane-Thickness Caliper. J Bacteriol (2016) 0.75
Energetics of side chain partitioning of β-signal residues in unassisted folding of a transmembrane β-barrel protein. J Biol Chem (2017) 0.75
Efficient site-directed mutagenesis using uracil-containing DNA. Methods Enzymol (1991) 7.94
Receptor sensitivity in bacterial chemotaxis. Proc Natl Acad Sci U S A (2001) 5.90
Four-helical-bundle structure of the cytoplasmic domain of a serine chemotaxis receptor. Nature (1999) 5.38
The two-component signaling pathway of bacterial chemotaxis: a molecular view of signal transduction by receptors, kinases, and adaptation enzymes. Annu Rev Cell Dev Biol (1997) 4.99
Three-dimensional structures of the ligand-binding domain of the bacterial aspartate receptor with and without a ligand. Science (1991) 4.71
Transmembrane signaling in bacterial chemoreceptors. Trends Biochem Sci (2001) 4.69
Collaborative signaling by mixed chemoreceptor teams in Escherichia coli. Proc Natl Acad Sci U S A (2002) 4.64
How proteins adapt to a membrane-water interface. Trends Biochem Sci (2000) 3.76
A piston model for transmembrane signaling of the aspartate receptor. Science (1999) 3.42
Chimeric chemosensory transducers of Escherichia coli. Proc Natl Acad Sci U S A (1985) 3.38
Site-directed cross-linking. Establishing the dimeric structure of the aspartate receptor of bacterial chemotaxis. J Biol Chem (1988) 3.28
Determination of transmembrane protein structure by disulfide cross-linking: the Escherichia coli Tar receptor. Proc Natl Acad Sci U S A (1992) 2.94
Molecular mechanism of transmembrane signaling by the aspartate receptor: a model. Proc Natl Acad Sci U S A (1996) 2.74
Molecular information processing: lessons from bacterial chemotaxis. J Biol Chem (2002) 2.72
Bacterial tactic responses. Adv Microb Physiol (1999) 2.45
Cysteine and disulfide scanning reveals two amphiphilic helices in the linker region of the aspartate chemoreceptor. Biochemistry (1998) 2.23
Transmembrane signaling by the aspartate receptor: engineered disulfides reveal static regions of the subunit interface. Biochemistry (1995) 2.12
Polarity in action: asymmetric protein localization in bacteria. J Bacteriol (2001) 2.05
A diffusion assay for detection and quantitation of methyl-esterified proteins on polyacrylamide gels. Anal Biochem (1984) 2.02
Lock on/off disulfides identify the transmembrane signaling helix of the aspartate receptor. J Biol Chem (1995) 1.99
Common extracellular sensory domains in transmembrane receptors for diverse signal transduction pathways in bacteria and archaea. J Bacteriol (2003) 1.97
Deducing the organization of a transmembrane domain by disulfide cross-linking. The bacterial chemoreceptor Trg. J Biol Chem (1994) 1.88
Attractant regulation of the aspartate receptor-kinase complex: limited cooperative interactions between receptors and effects of the receptor modification state. Biochemistry (2000) 1.70
Transmembrane signalling by a hybrid protein: communication from the domain of chemoreceptor Trg that recognizes sugar-binding proteins to the kinase/phosphatase domain of osmosensor EnvZ. J Bacteriol (1994) 1.66
Aspartate receptors of Escherichia coli and Salmonella typhimurium bind ligand with negative and half-of-the-sites cooperativity. Biochemistry (1994) 1.64
Detecting the conformational change of transmembrane signaling in a bacterial chemoreceptor by measuring effects on disulfide cross-linking in vivo. Proc Natl Acad Sci U S A (1996) 1.63
The aspartate receptor cytoplasmic domain: in situ chemical analysis of structure, mechanism and dynamics. Structure (1999) 1.59
Imitation of Escherichia coli aspartate receptor signaling in engineered dimers of the cytoplasmic domain. Science (1996) 1.56
Additive and independent responses in a single receptor: aspartate and maltose stimuli on the tar protein. Cell (1987) 1.54
The serine receptor of bacterial chemotaxis exhibits half-site saturation for serine binding. Biochemistry (1994) 1.50
Quantitative analysis of aspartate receptor signaling complex reveals that the homogeneous two-state model is inadequate: development of a heterogeneous two-state model. J Mol Biol (2003) 1.38
Positively and negatively charged residues have different effects on the position in the membrane of a model transmembrane helix. J Mol Biol (1998) 1.27
A model for transmembrane signalling by the aspartate receptor based on random-cassette mutagenesis and site-directed disulfide cross-linking. J Mol Biol (1995) 1.26
Mapping out regions on the surface of the aspartate receptor that are essential for kinase activation. Biochemistry (2003) 1.17
An archaeal photosignal-transducing module mediates phototaxis in Escherichia coli. J Bacteriol (2001) 1.14
Ca2(+)-enhanced phosphorylation of a chimeric protein kinase involved with bacterial signal transduction. J Biol Chem (1991) 1.04
Membrane-anchoring interactions of M13 major coat protein. Biochemistry (2001) 1.01
Maltose-binding protein interacts simultaneously and asymmetrically with both subunits of the Tar chemoreceptor. Mol Microbiol (1997) 0.95
Site-directed rotational resonance solid-state NMR distance measurements probe structure and mechanism in the transmembrane domain of the serine bacterial chemoreceptor. Biochemistry (2002) 0.87
Bacterial chemoreceptors: high-performance signaling in networked arrays. Trends Biochem Sci (2007) 5.28
Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain Behav Immun (2009) 2.19
Ca2+ influx is an essential component of the positive-feedback loop that maintains leading-edge structure and activity in macrophages. Proc Natl Acad Sci U S A (2007) 1.81
Structure of the conserved HAMP domain in an intact, membrane-bound chemoreceptor: a disulfide mapping study. Biochemistry (2007) 1.80
Use of site-directed cysteine and disulfide chemistry to probe protein structure and dynamics: applications to soluble and transmembrane receptors of bacterial chemotaxis. Methods Enzymol (2007) 1.58
Membrane orientation and position of the C2 domain from cPLA2 by site-directed spin labeling. Biochemistry (2002) 1.57
Engineered socket study of signaling through a four-helix bundle: evidence for a yin-yang mechanism in the kinase control module of the aspartate receptor. Biochemistry (2009) 1.51
Adaptation mechanism of the aspartate receptor: electrostatics of the adaptation subdomain play a key role in modulating kinase activity. Biochemistry (2005) 1.51
CheA Kinase of bacterial chemotaxis: chemical mapping of four essential docking sites. Biochemistry (2006) 1.49
GRP1 pleckstrin homology domain: activation parameters and novel search mechanism for rare target lipid. Biochemistry (2004) 1.48
Specific translocation of protein kinase Calpha to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain. Mol Biol Cell (2005) 1.47
The core signaling proteins of bacterial chemotaxis assemble to form an ultrastable complex. Biochemistry (2009) 1.46
Conserved glycine residues in the cytoplasmic domain of the aspartate receptor play essential roles in kinase coupling and on-off switching. Biochemistry (2005) 1.44
Single-molecule fluorescence studies of a PH domain: new insights into the membrane docking reaction. Biophys J (2009) 1.44
Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity. Biochemistry (2007) 1.42
C2 domain of protein kinase C alpha: elucidation of the membrane docking surface by site-directed fluorescence and spin labeling. Biochemistry (2003) 1.40
C2 domains of protein kinase C isoforms alpha, beta, and gamma: activation parameters and calcium stoichiometries of the membrane-bound state. Biochemistry (2002) 1.39
Quantitative analysis of aspartate receptor signaling complex reveals that the homogeneous two-state model is inadequate: development of a heterogeneous two-state model. J Mol Biol (2003) 1.38
Single molecule diffusion of membrane-bound proteins: window into lipid contacts and bilayer dynamics. Biophys J (2010) 1.35
Molecular mechanism of an oncogenic mutation that alters membrane targeting: Glu17Lys modifies the PIP lipid specificity of the AKT1 PH domain. Biochemistry (2008) 1.30
Membrane-docking loops of the cPLA2 C2 domain: detailed structural analysis of the protein-membrane interface via site-directed spin-labeling. Biochemistry (2003) 1.28
Use of EPR power saturation to analyze the membrane-docking geometries of peripheral proteins: applications to C2 domains. Annu Rev Biophys Biomol Struct (2005) 1.23
Mapping out regions on the surface of the aspartate receptor that are essential for kinase activation. Biochemistry (2003) 1.17
Evidence that the adaptation region of the aspartate receptor is a dynamic four-helix bundle: cysteine and disulfide scanning studies. Biochemistry (2005) 1.15
Self-induced docking site of a deeply embedded peripheral membrane protein. Biophys J (2006) 1.14
Effect of PIP2 binding on the membrane docking geometry of PKC alpha C2 domain: an EPR site-directed spin-labeling and relaxation study. Biochemistry (2008) 1.07
Membrane docking geometry and target lipid stoichiometry of membrane-bound PKCα C2 domain: a combined molecular dynamics and experimental study. J Mol Biol (2010) 1.06
The 3.2 Å resolution structure of a receptor: CheA:CheW signaling complex defines overlapping binding sites and key residue interactions within bacterial chemosensory arrays. Biochemistry (2013) 1.05
Chemotaxis receptor complexes: from signaling to assembly. PLoS Comput Biol (2007) 1.04
The piston rises again. Structure (2009) 1.04
The PICM chemical scanning method for identifying domain-domain and protein-protein interfaces: applications to the core signaling complex of E. coli chemotaxis. Methods Enzymol (2007) 0.95
Use of fluorescence resonance energy transfer to monitor Ca(2+)-triggered membrane docking of C2 domains. Methods Mol Biol (2002) 0.95
New insights into bacterial chemoreceptor array structure and assembly from electron cryotomography. Biochemistry (2014) 0.94
Defining a key receptor-CheA kinase contact and elucidating its function in the membrane-bound bacterial chemosensory array: a disulfide mapping and TAM-IDS Study. Biochemistry (2013) 0.94
Lateral diffusion of peripheral membrane proteins on supported lipid bilayers is controlled by the additive frictional drags of (1) bound lipids and (2) protein domains penetrating into the bilayer hydrocarbon core. Chem Phys Lipids (2013) 0.93
The GRP1 PH domain, like the AKT1 PH domain, possesses a sentry glutamate residue essential for specific targeting to plasma membrane PI(3,4,5)P(3). Biochemistry (2011) 0.93
Thermal domain motions of CheA kinase in solution: Disulfide trapping reveals the motional constraints leading to trans-autophosphorylation. Biochemistry (2009) 0.92
Assembly of membrane-bound protein complexes: detection and analysis by single molecule diffusion. Biochemistry (2012) 0.90
Isolated bacterial chemosensory array possesses quasi- and ultrastable components: functional links between array stability, cooperativity, and order. Biochemistry (2012) 0.89
Single-molecule studies reveal a hidden key step in the activation mechanism of membrane-bound protein kinase C-α. Biochemistry (2014) 0.88
Molecular mechanism of membrane binding of the GRP1 PH domain. J Mol Biol (2013) 0.87
Ca2+ activation of the cPLA2 C2 domain: ordered binding of two Ca2+ ions with positive cooperativity. Biochemistry (2004) 0.86
Chemotaxis receptors and signaling. Adv Protein Chem (2004) 0.85
Membrane docking geometry of GRP1 PH domain bound to a target lipid bilayer: an EPR site-directed spin-labeling and relaxation study. PLoS One (2012) 0.84
Structure, function, and on-off switching of a core unit contact between CheA kinase and CheW adaptor protein in the bacterial chemosensory array: A disulfide mapping and mutagenesis study. Biochemistry (2013) 0.84
Hydrophobic contributions to the membrane docking of synaptotagmin 7 C2A domain: mechanistic contrast between isoforms 1 and 7. Biochemistry (2012) 0.82
Increasing and decreasing the ultrastability of bacterial chemotaxis core signaling complexes by modifying protein-protein contacts. Biochemistry (2014) 0.81
Interactions of protein kinase C-α C1A and C1B domains with membranes: a combined computational and experimental study. J Am Chem Soc (2014) 0.80
The PH domain of phosphoinositide-dependent kinase-1 exhibits a novel, phospho-regulated monomer-dimer equilibrium with important implications for kinase domain activation: single-molecule and ensemble studies. Biochemistry (2013) 0.80
Cation charge and size selectivity of the C2 domain of cytosolic phospholipase A(2). Biochemistry (2002) 0.78
OS-FRET: a new one-sample method for improved FRET measurements. Biochemistry (2010) 0.76
Reprint of: Purification of Proteins Using Polyhistidine Affinity Tags. Protein Expr Purif (2011) 0.75