Published in Biochemistry on February 24, 2004
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol Cell (2005) 11.19
Immunogenicity of induced pluripotent stem cells. Nature (2011) 7.31
p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression. Nat Cell Biol (2004) 5.82
Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection. J Clin Oncol (2007) 5.28
Serum DKK1 as a protein biomarker for the diagnosis of hepatocellular carcinoma: a large-scale, multicentre study. Lancet Oncol (2012) 4.21
p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM. Nat Cell Biol (2007) 3.86
Overexpression of PD-L1 significantly associates with tumor aggressiveness and postoperative recurrence in human hepatocellular carcinoma. Clin Cancer Res (2009) 3.39
Functional analysis of the roles of posttranslational modifications at the p53 C terminus in regulating p53 stability and activity. Mol Cell Biol (2005) 2.72
Involvement of receptor-interacting protein 2 in innate and adaptive immune responses. Nature (2002) 2.60
Molecular symmetry in mitochondrial cardiolipins. Chem Phys Lipids (2005) 2.23
Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour. Nature (2016) 2.21
Modeling disease in human ESCs using an efficient BAC-based homologous recombination system. Cell Stem Cell (2010) 2.19
Ser18 and 23 phosphorylation is required for p53-dependent apoptosis and tumor suppression. EMBO J (2006) 2.12
The Effect of Erythropoietin-Stimulating Agents on Health-Related Quality of Life in Anemia of Chronic Kidney Disease: A Systematic Review and Meta-analysis. Ann Intern Med (2016) 2.09
Cytotoxicity effects of graphene and single-wall carbon nanotubes in neural phaeochromocytoma-derived PC12 cells. ACS Nano (2010) 2.05
Cell type- and promoter-specific roles of Ser18 phosphorylation in regulating p53 responses. J Biol Chem (2003) 2.02
Incidence of second malignancies among patients treated with proton versus photon radiation. Int J Radiat Oncol Biol Phys (2013) 1.89
Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma. Cancer Res (2008) 1.85
Circulating stem cell-like epithelial cell adhesion molecule-positive tumor cells indicate poor prognosis of hepatocellular carcinoma after curative resection. Hepatology (2013) 1.84
Proteomic fingerprints for potential application to early diagnosis of severe acute respiratory syndrome. Clin Chem (2004) 1.76
Retracted Carbon nanotubes are able to penetrate plant seed coat and dramatically affect seed germination and plant growth. ACS Nano (2009) 1.73
Coexistence of hepatitis B surface antigen (HBsAg) and heterologous subtype-specific antibodies to HBsAg among patients with chronic hepatitis B virus infection. Clin Infect Dis (2007) 1.69
Mutation of mouse p53 Ser23 and the response to DNA damage. Mol Cell Biol (2002) 1.65
A DNA nanostructure platform for directed assembly of synthetic vaccines. Nano Lett (2012) 1.64
Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair. EMBO J (2002) 1.64
Phosphorylation site interdependence of human p53 post-translational modifications in response to stress. J Biol Chem (2003) 1.63
Essential roles of the kappa light chain intronic enhancer and 3' enhancer in kappa rearrangement and demethylation. Nat Immunol (2002) 1.63
Cardiolipin affects the supramolecular organization of ATP synthase in mitochondria. Biophys J (2011) 1.57
Phosphorylation stabilizes Nanog by promoting its interaction with Pin1. Proc Natl Acad Sci U S A (2010) 1.57
Pharmacokinetics of ertapenem in patients with varying degrees of renal insufficiency and in patients on hemodialysis. J Clin Pharmacol (2006) 1.56
Role of overexpression of CD151 and/or c-Met in predicting prognosis of hepatocellular carcinoma. Hepatology (2009) 1.56
Liver-intestine cadherin predicts microvascular invasion and poor prognosis of hepatitis B virus-positive hepatocellular carcinoma. Cancer (2009) 1.54
p53 and stem cells: new developments and new concerns. Trends Cell Biol (2010) 1.53
Role of calcium-independent phospholipase A2 in the pathogenesis of Barth syndrome. Proc Natl Acad Sci U S A (2009) 1.51
Proteomic characteristics of human sperm cryopreservation. Proteomics (2014) 1.51
Variegation mutants and mechanisms of chloroplast biogenesis. Plant Cell Environ (2007) 1.50
Acetylation of mouse p53 at lysine 317 negatively regulates p53 apoptotic activities after DNA damage. Mol Cell Biol (2006) 1.45
The hepatitis B virus X protein disrupts innate immunity by downregulating mitochondrial antiviral signaling protein. J Immunol (2010) 1.44
Atomic structure, energetics, and dynamics of topological solitons in indium chains on Si(111) surfaces. Phys Rev Lett (2011) 1.42
Puma is required for p53-induced depletion of adult stem cells. Nat Cell Biol (2010) 1.41
A genomewide study identifies the Wnt signaling pathway as a major target of p53 in murine embryonic stem cells. Proc Natl Acad Sci U S A (2009) 1.41
Up-regulation of Krüppel-like factor 8 promotes tumor invasion and indicates poor prognosis for hepatocellular carcinoma. Gastroenterology (2010) 1.37
Anti-tumor activities of matrine and oxymatrine: literature review. Tumour Biol (2014) 1.33
CD151 modulates expression of matrix metalloproteinase 9 and promotes neoangiogenesis and progression of hepatocellular carcinoma. Hepatology (2010) 1.32
Comparison of lymphoblast mitochondria from normal subjects and patients with Barth syndrome using electron microscopic tomography. Lab Invest (2006) 1.32
Characterization of domain-peptide interaction interface: a generic structure-based model to decipher the binding specificity of SH3 domains. Mol Cell Proteomics (2008) 1.31
Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression. Mol Cell Biol (2005) 1.31
FTY720: a promising agent for treatment of metastatic hepatocellular carcinoma. Clin Cancer Res (2005) 1.29
Circulating tumor cells: advances in detection methods, biological issues, and clinical relevance. J Cancer Res Clin Oncol (2011) 1.29
Formation of molecular species of mitochondrial cardiolipin. 1. A novel transacylation mechanism to shuttle fatty acids between sn-1 and sn-2 positions of multiple phospholipid species. Biochim Biophys Acta (2009) 1.28
Identification of side population cells in human hepatocellular carcinoma cell lines with stepwise metastatic potentials. J Cancer Res Clin Oncol (2008) 1.28
Important roles for E protein binding sites within the immunoglobulin kappa chain intronic enhancer in activating Vkappa Jkappa rearrangement. J Exp Med (2004) 1.27
Generation of transgenic maize with enhanced provitamin A content. J Exp Bot (2008) 1.26
Association between the Igk and Igh immunoglobulin loci mediated by the 3' Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells. Nat Immunol (2008) 1.24
Negative regulation of MAVS-mediated innate immune response by PSMA7. J Immunol (2009) 1.24
CD24 is a novel predictor for poor prognosis of hepatocellular carcinoma after surgery. Clin Cancer Res (2009) 1.22
DNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53. EMBO J (2002) 1.21
Overexpression of platelet-derived growth factor receptor alpha in endothelial cells of hepatocellular carcinoma associated with high metastatic potential. Clin Cancer Res (2005) 1.19
Comorbidity of posttraumatic stress disorder with alcohol dependence among US adults: results from National Epidemiological Survey on Alcohol and Related Conditions. Drug Alcohol Depend (2013) 1.19
p53, oxidative stress, and aging. Antioxid Redox Signal (2011) 1.18
CXCL16 functions as a novel chemotactic factor for prostate cancer cells in vitro. Mol Cancer Res (2008) 1.18
Stable aqueous ZnO@polymer core-shell nanoparticles with tunable photoluminescence and their application in cell imaging. J Am Chem Soc (2008) 1.16
Evidence for the direct binding of phosphorylated p53 to sites of DNA breaks in vivo. Cancer Res (2005) 1.16
Elevated expression of DKK1 is associated with cytoplasmic/nuclear beta-catenin accumulation and poor prognosis in hepatocellular carcinomas. J Hepatol (2009) 1.16
The physical state of lipid substrates provides transacylation specificity for tafazzin. Nat Chem Biol (2012) 1.15
Expression of X-linked inhibitor-of-apoptosis protein in hepatocellular carcinoma promotes metastasis and tumor recurrence. Hepatology (2008) 1.15
Yes-associated protein regulates the hepatic response after bile duct ligation. Hepatology (2012) 1.15
Ser46 phosphorylation regulates p53-dependent apoptosis and replicative senescence. Cell Cycle (2006) 1.15
Experimental demonstration of a free-space cylindrical cloak without superluminal propagation. Phys Rev Lett (2012) 1.14
Modeling, prediction, and in vitro in vivo correlation of CYP3A4 induction. Drug Metab Dispos (2008) 1.14
The role of polymeric immunoglobulin receptor in inflammation-induced tumor metastasis of human hepatocellular carcinoma. J Natl Cancer Inst (2011) 1.14
HERV-K-specific T cells eliminate diverse HIV-1/2 and SIV primary isolates. J Clin Invest (2012) 1.14
Cytokeratin 10 and cytokeratin 19: predictive markers for poor prognosis in hepatocellular carcinoma patients after curative resection. Clin Cancer Res (2008) 1.13
The amino Acid residues at positions 120 to 123 are crucial for the antigenicity of hepatitis B surface antigen. J Clin Microbiol (2007) 1.12
Liver transplantation outcomes in 1,078 hepatocellular carcinoma patients: a multi-center experience in Shanghai, China. J Cancer Res Clin Oncol (2009) 1.12
P48 is a predictive marker for outcome of postoperative interferon-alpha treatment in patients with hepatitis B virus infection-related hepatocellular carcinoma. Cancer (2006) 1.11
Decoding and cortical source localization for intended movement direction with MEG. J Neurophysiol (2010) 1.10
Discovery of aryl aminoquinazoline pyridones as potent, selective, and orally efficacious inhibitors of receptor tyrosine kinase c-Kit. J Med Chem (2008) 1.08
Hepatitis B virus polymerase impairs interferon-α-induced STA T activation through inhibition of importin-α5 and protein kinase C-δ. Hepatology (2013) 1.08
Targeting radiation-induced G(2) checkpoint activation with the Wee-1 inhibitor MK-1775 in glioblastoma cell lines. Mol Cancer Ther (2011) 1.08
Osteopontin combined with CD44, a novel prognostic biomarker for patients with hepatocellular carcinoma undergoing curative resection. Oncologist (2008) 1.08
Radical nanomedicine. Nanomedicine (Lond) (2006) 1.06
Blockade of platelet-derived growth factor receptor-beta pathway induces apoptosis of vascular endothelial cells and disrupts glomerular capillary formation in neonatal mice. Am J Pathol (2002) 1.05
Selection of reference genes for real-time PCR in human hepatocellular carcinoma tissues. J Cancer Res Clin Oncol (2008) 1.05
From bortezomib to other inhibitors of the proteasome and beyond. Curr Pharm Des (2013) 1.04
R/BHC: fast Bayesian hierarchical clustering for microarray data. BMC Bioinformatics (2009) 1.04
Homologous recombination in human embryonic stem cells using CRISPR/Cas9 nickase and a long DNA donor template. Protein Cell (2014) 1.04
Mechanistic toxicity evaluation of uncoated and PEGylated single-walled carbon nanotubes in neuronal PC12 cells. ACS Nano (2011) 1.03
Hepatitis B virus polymerase inhibits the interferon-inducible MyD88 promoter by blocking nuclear translocation of Stat1. J Gen Virol (2007) 1.03
Gain of function of p53 cancer mutants in disrupting critical DNA damage response pathways. Cell Cycle (2007) 1.03
In vivo Raman flow cytometry for real-time detection of carbon nanotube kinetics in lymph, blood, and tissues. J Biomed Opt (2009) 1.02
Flexible surface acoustic wave resonators built on disposable plastic film for electronics and lab-on-a-chip applications. Sci Rep (2013) 1.02
Molecular epidemiological and virological study of dengue virus infections in Guangzhou, China, during 2001-2010. Virol J (2013) 1.01
Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin. Nat Commun (2013) 1.01
Genome integrity: linking pluripotency and tumorgenicity. Trends Genet (2009) 1.01
DNA immunization with fusion of CTLA-4 to hepatitis B virus (HBV) core protein enhanced Th2 type responses and cleared HBV with an accelerated kinetic. PLoS One (2011) 1.01
Effect of sanguinarine from the leaves of Macleaya cordata against Ichthyophthirius multifiliis in grass carp (Ctenopharyngodon idella). Parasitol Res (2010) 1.01
Critical roles of the immunoglobulin intronic enhancers in maintaining the sequential rearrangement of IgH and Igk loci. J Exp Med (2006) 1.01
Roles of the Ig kappa light chain intronic and 3' enhancers in Igk somatic hypermutation. J Immunol (2006) 1.00