Pascal Schneider

Author PubWeight™ 128.42‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. Cell 2007 7.74
2 BAFF AND APRIL: a tutorial on B cell survival. Annu Rev Immunol 2001 4.87
3 Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome. J Clin Invest 2002 4.14
4 Cracking the BAFF code. Nat Rev Immunol 2009 3.95
5 The molecular architecture of the TNF superfamily. Trends Biochem Sci 2002 3.39
6 The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex. J Biol Chem 2002 2.75
7 Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human. J Biol Chem 2006 2.75
8 T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes. Nature 2009 2.59
9 Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex. Mol Cell Biol 2003 2.50
10 Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland. Proc Natl Acad Sci U S A 2010 2.45
11 APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells. Blood 2008 2.44
12 TL1A-DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease. J Exp Med 2008 2.33
13 TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha. J Cell Biol 2008 2.11
14 Progesterone/RANKL is a major regulatory axis in the human breast. Sci Transl Med 2013 2.09
15 BAFF, APRIL and their receptors: structure, function and signaling. Semin Immunol 2006 2.09
16 Identification of proteoglycans as the APRIL-specific binding partners. J Exp Med 2005 2.03
17 TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts. Blood 2007 1.85
18 Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes. Blood 2008 1.83
19 Permanent correction of an inherited ectodermal dysplasia with recombinant EDA. Nat Med 2003 1.75
20 TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration. EMBO J 2006 1.73
21 Generation of the primary hair follicle pattern. Proc Natl Acad Sci U S A 2006 1.72
22 NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth. Development 2006 1.66
23 Efficient generation of human alloantigen-specific CD4+ regulatory T cells from naive precursors by CD40-activated B cells. Blood 2008 1.64
24 Fas ligand elicits a caspase-independent proinflammatory response in human keratinocytes: implications for dermatitis. J Invest Dermatol 2006 1.64
25 TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality. J Clin Invest 2006 1.55
26 Ectodysplasin has a dual role in ectodermal organogenesis: inhibition of Bmp activity and induction of Shh expression. Development 2007 1.53
27 Ectodysplasin A1 promotes placodal cell fate during early morphogenesis of ectodermal appendages. Development 2004 1.53
28 Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2. Mol Cell Biol 2006 1.52
29 APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa. J Clin Invest 2008 1.50
30 TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma. J Immunol 2004 1.47
31 Human cytomegalovirus glycoprotein UL141 targets the TRAIL death receptors to thwart host innate antiviral defenses. Cell Host Microbe 2013 1.41
32 TACI, an enigmatic BAFF/APRIL receptor, with new unappreciated biochemical and biological properties. Cytokine Growth Factor Rev 2008 1.35
33 Differential insertion of GPI-anchored GFPs into lipid rafts of live cells. FASEB J 2004 1.33
34 BAFF is a survival and maturation factor for mouse B cells. Eur J Immunol 2002 1.31
35 BAFF production by antigen-presenting cells provides T cell co-stimulation. Int Immunol 2004 1.29
36 Significant correction of disease after postnatal administration of recombinant ectodysplasin A in canine X-linked ectodermal dysplasia. Am J Hum Genet 2007 1.20
37 Intestinal bacteria condition dendritic cells to promote IgA production. PLoS One 2008 1.13
38 The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF. Eur J Immunol 2004 1.08
39 Neutrophil-derived APRIL concentrated in tumor lesions by proteoglycans correlates with human B-cell lymphoma aggressiveness. Blood 2007 1.08
40 Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis. Immunity 2009 1.07
41 A role for the src family kinase Fyn in NK cell activation and the formation of the repertoire of Ly49 receptors. Eur J Immunol 2002 1.06
42 Development of an Fn14 agonistic antibody as an anti-tumor agent. MAbs 2011 1.04
43 Soluble MHC-peptide complexes induce rapid death of CD8+ CTL. J Immunol 2005 1.04
44 A secreted high-affinity inhibitor of human TNF from Tanapox virus. Proc Natl Acad Sci U S A 2003 1.02
45 Aggregation of integrins and RhoA activation are required for Thy-1-induced morphological changes in astrocytes. J Biol Chem 2004 1.02
46 The human cytomegalovirus-encoded chemokine receptor US28 induces caspase-dependent apoptosis. FEBS J 2005 1.01
47 C3-symmetric peptide scaffolds are functional mimetics of trimeric CD40L. Nat Chem Biol 2005 1.01
48 Ectodysplasin regulates hormone-independent mammary ductal morphogenesis via NF-κB. Proc Natl Acad Sci U S A 2012 0.99
49 Productive HIV-1 infection of primary CD4+ T cells induces mitochondrial membrane permeabilization leading to a caspase-independent cell death. J Biol Chem 2001 0.99
50 Formation of virus-like clusters is an intrinsic property of the tumor necrosis factor family member BAFF (B cell activating factor). Biochemistry 2006 0.99
51 Mutation of the BAFF furin cleavage site impairs B-cell homeostasis and antibody responses. Eur J Immunol 2011 0.98
52 Alveolar macrophages and lung dendritic cells sense RNA and drive mucosal IgA responses. J Immunol 2009 0.98
53 Functional analysis of Ectodysplasin-A mutations causing selective tooth agenesis. Eur J Hum Genet 2010 0.98
54 The oncogene metadherin modulates the apoptotic pathway based on the tumor necrosis factor superfamily member TRAIL (Tumor Necrosis Factor-related Apoptosis-inducing Ligand) in breast cancer. J Biol Chem 2013 0.97
55 Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by PolyIC in vivo. PLoS One 2011 0.97
56 Direct Thy-1/alphaVbeta3 integrin interaction mediates neuron to astrocyte communication. Biochim Biophys Acta 2008 0.97
57 Fas ligand-induced proinflammatory transcriptional responses in reconstructed human epidermis. Recruitment of the epidermal growth factor receptor and activation of MAP kinases. J Biol Chem 2007 0.96
58 Neonatal treatment with recombinant ectodysplasin prevents respiratory disease in dogs with X-linked ectodermal dysplasia. Am J Med Genet A 2009 0.96
59 Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with alphavbeta3 integrin that activates PKCalpha and RhoA. J Cell Sci 2009 0.95
60 Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis. Proc Natl Acad Sci U S A 2012 0.95
61 Identification of ectodysplasin target genes reveals the involvement of chemokines in hair development. J Invest Dermatol 2012 0.94
62 Probing the interaction between feline immunodeficiency virus and CD134 by using the novel monoclonal antibody 7D6 and the CD134 (Ox40) ligand. J Virol 2007 0.94
63 Biological activity of ectodysplasin A is conditioned by its collagen and heparan sulfate proteoglycan-binding domains. J Biol Chem 2009 0.92
64 Toll-like receptor agonists synergize with CD40L to induce either proliferation or plasma cell differentiation of mouse B cells. PLoS One 2011 0.92
65 Cell death-induced activation of epidermal growth factor receptor in keratinocytes: implications for restricting epidermal damage in dermatitis. J Invest Dermatol 2005 0.91
66 Induction of the alternative NF-κB pathway by lymphotoxin αβ (LTαβ) relies on internalization of LTβ receptor. Mol Cell Biol 2011 0.90
67 RANKL expression, function, and therapeutic targeting in multiple myeloma and chronic lymphocytic leukemia. Cancer Res 2012 0.90
68 Chicken BAFF--a highly conserved cytokine that mediates B cell survival. Int Immunol 2004 0.89
69 Molecular and therapeutic characterization of anti-ectodysplasin A receptor (EDAR) agonist monoclonal antibodies. J Biol Chem 2011 0.88
70 ATP release due to Thy-1-integrin binding induces P2X7-mediated calcium entry required for focal adhesion formation. J Cell Sci 2011 0.86
71 Unique and conserved functions of B cell-activating factor of the TNF family (BAFF) in the chicken. Int Immunol 2007 0.86
72 Distribution of the human intracellular serpin protease inhibitor 8 in human tissues. J Histochem Cytochem 2002 0.86
73 The design and characterization of receptor-selective APRIL variants. J Biol Chem 2012 0.86
74 Structure-function analysis of Eiger, the Drosophila TNF homolog. Cell Res 2009 0.85
75 Theileria parva-transformed T cells show enhanced resistance to Fas/Fas ligand-induced apoptosis. J Immunol 2003 0.85
76 Astrocytic αVβ3 integrin inhibits neurite outgrowth and promotes retraction of neuronal processes by clustering Thy-1. PLoS One 2012 0.84
77 Transduction of CpG DNA-stimulated primary human B cells with bicistronic lentivectors. Mol Ther 2005 0.84
78 Programming of marginal zone B-cell fate by basic Kruppel-like factor (BKLF/KLF3). Blood 2011 0.84
79 Thy-1-mediated cell-cell contact induces astrocyte migration through the engagement of αVβ3 integrin and syndecan-4. Biochim Biophys Acta 2013 0.83
80 Cysteine-rich domain 1 of CD40 mediates receptor self-assembly. J Biol Chem 2013 0.83
81 The C76R transmembrane activator and calcium modulator cyclophilin ligand interactor mutation disrupts antibody production and B-cell homeostasis in heterozygous and homozygous mice. J Allergy Clin Immunol 2011 0.82
82 Receptor activator for NF-κB ligand in acute myeloid leukemia: expression, function, and modulation of NK cell immunosurveillance. J Immunol 2012 0.81
83 Effects of fructose-containing caloric sweeteners on resting energy expenditure and energy efficiency: a review of human trials. Nutr Metab (Lond) 2013 0.80
84 Rescue of the mature B cell compartment in BAFF-deficient mice by treatment with recombinant Fc-BAFF. Immunol Lett 2010 0.80
85 Enforced covalent trimerisation of soluble feline CD134 (OX40)-ligand generates a functional antagonist of feline immunodeficiency virus. Mol Immunol 2009 0.79
86 Structure of the extracellular domains of human and Xenopus Fn14: implications in the evolution of TWEAK and Fn14 interactions. FEBS J 2013 0.78
87 Generation and characterization of function-blocking anti-ectodysplasin A (EDA) monoclonal antibodies that induce ectodermal dysplasia. J Biol Chem 2014 0.78
88 Therapeutic blockade of LIGHT interaction with herpesvirus entry mediator and lymphotoxin β receptor attenuates in vivo cytotoxic allogeneic responses. Transplantation 2014 0.77
89 No evidence that soluble TACI induces signalling via membrane-expressed BAFF and APRIL in myeloid cells. PLoS One 2013 0.77
90 Buffy's, B cells, and membrane BAFF. Arthritis Rheum 2010 0.75
91 Heparan sulfate proteoglycans, Fc receptors, and DC suppression. Blood 2008 0.75
92 Rationally-designed multivalent architectures for mimicking homotrimers of CD40L, a member of the TNF superfamily. Adv Exp Med Biol 2009 0.75