1
|
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis.
|
Cell
|
2007
|
7.74
|
2
|
BAFF AND APRIL: a tutorial on B cell survival.
|
Annu Rev Immunol
|
2001
|
4.87
|
3
|
Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome.
|
J Clin Invest
|
2002
|
4.14
|
4
|
Cracking the BAFF code.
|
Nat Rev Immunol
|
2009
|
3.95
|
5
|
The molecular architecture of the TNF superfamily.
|
Trends Biochem Sci
|
2002
|
3.39
|
6
|
The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex.
|
J Biol Chem
|
2002
|
2.75
|
7
|
Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human.
|
J Biol Chem
|
2006
|
2.75
|
8
|
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
|
Nature
|
2009
|
2.59
|
9
|
Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex.
|
Mol Cell Biol
|
2003
|
2.50
|
10
|
Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland.
|
Proc Natl Acad Sci U S A
|
2010
|
2.45
|
11
|
APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells.
|
Blood
|
2008
|
2.44
|
12
|
TL1A-DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease.
|
J Exp Med
|
2008
|
2.33
|
13
|
TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha.
|
J Cell Biol
|
2008
|
2.11
|
14
|
Progesterone/RANKL is a major regulatory axis in the human breast.
|
Sci Transl Med
|
2013
|
2.09
|
15
|
BAFF, APRIL and their receptors: structure, function and signaling.
|
Semin Immunol
|
2006
|
2.09
|
16
|
Identification of proteoglycans as the APRIL-specific binding partners.
|
J Exp Med
|
2005
|
2.03
|
17
|
TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts.
|
Blood
|
2007
|
1.85
|
18
|
Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes.
|
Blood
|
2008
|
1.83
|
19
|
Permanent correction of an inherited ectodermal dysplasia with recombinant EDA.
|
Nat Med
|
2003
|
1.75
|
20
|
TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration.
|
EMBO J
|
2006
|
1.73
|
21
|
Generation of the primary hair follicle pattern.
|
Proc Natl Acad Sci U S A
|
2006
|
1.72
|
22
|
NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth.
|
Development
|
2006
|
1.66
|
23
|
Efficient generation of human alloantigen-specific CD4+ regulatory T cells from naive precursors by CD40-activated B cells.
|
Blood
|
2008
|
1.64
|
24
|
Fas ligand elicits a caspase-independent proinflammatory response in human keratinocytes: implications for dermatitis.
|
J Invest Dermatol
|
2006
|
1.64
|
25
|
TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality.
|
J Clin Invest
|
2006
|
1.55
|
26
|
Ectodysplasin has a dual role in ectodermal organogenesis: inhibition of Bmp activity and induction of Shh expression.
|
Development
|
2007
|
1.53
|
27
|
Ectodysplasin A1 promotes placodal cell fate during early morphogenesis of ectodermal appendages.
|
Development
|
2004
|
1.53
|
28
|
Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2.
|
Mol Cell Biol
|
2006
|
1.52
|
29
|
APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa.
|
J Clin Invest
|
2008
|
1.50
|
30
|
TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma.
|
J Immunol
|
2004
|
1.47
|
31
|
Human cytomegalovirus glycoprotein UL141 targets the TRAIL death receptors to thwart host innate antiviral defenses.
|
Cell Host Microbe
|
2013
|
1.41
|
32
|
TACI, an enigmatic BAFF/APRIL receptor, with new unappreciated biochemical and biological properties.
|
Cytokine Growth Factor Rev
|
2008
|
1.35
|
33
|
Differential insertion of GPI-anchored GFPs into lipid rafts of live cells.
|
FASEB J
|
2004
|
1.33
|
34
|
BAFF is a survival and maturation factor for mouse B cells.
|
Eur J Immunol
|
2002
|
1.31
|
35
|
BAFF production by antigen-presenting cells provides T cell co-stimulation.
|
Int Immunol
|
2004
|
1.29
|
36
|
Significant correction of disease after postnatal administration of recombinant ectodysplasin A in canine X-linked ectodermal dysplasia.
|
Am J Hum Genet
|
2007
|
1.20
|
37
|
Intestinal bacteria condition dendritic cells to promote IgA production.
|
PLoS One
|
2008
|
1.13
|
38
|
The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF.
|
Eur J Immunol
|
2004
|
1.08
|
39
|
Neutrophil-derived APRIL concentrated in tumor lesions by proteoglycans correlates with human B-cell lymphoma aggressiveness.
|
Blood
|
2007
|
1.08
|
40
|
Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis.
|
Immunity
|
2009
|
1.07
|
41
|
A role for the src family kinase Fyn in NK cell activation and the formation of the repertoire of Ly49 receptors.
|
Eur J Immunol
|
2002
|
1.06
|
42
|
Development of an Fn14 agonistic antibody as an anti-tumor agent.
|
MAbs
|
2011
|
1.04
|
43
|
Soluble MHC-peptide complexes induce rapid death of CD8+ CTL.
|
J Immunol
|
2005
|
1.04
|
44
|
A secreted high-affinity inhibitor of human TNF from Tanapox virus.
|
Proc Natl Acad Sci U S A
|
2003
|
1.02
|
45
|
Aggregation of integrins and RhoA activation are required for Thy-1-induced morphological changes in astrocytes.
|
J Biol Chem
|
2004
|
1.02
|
46
|
The human cytomegalovirus-encoded chemokine receptor US28 induces caspase-dependent apoptosis.
|
FEBS J
|
2005
|
1.01
|
47
|
C3-symmetric peptide scaffolds are functional mimetics of trimeric CD40L.
|
Nat Chem Biol
|
2005
|
1.01
|
48
|
Ectodysplasin regulates hormone-independent mammary ductal morphogenesis via NF-κB.
|
Proc Natl Acad Sci U S A
|
2012
|
0.99
|
49
|
Productive HIV-1 infection of primary CD4+ T cells induces mitochondrial membrane permeabilization leading to a caspase-independent cell death.
|
J Biol Chem
|
2001
|
0.99
|
50
|
Formation of virus-like clusters is an intrinsic property of the tumor necrosis factor family member BAFF (B cell activating factor).
|
Biochemistry
|
2006
|
0.99
|
51
|
Mutation of the BAFF furin cleavage site impairs B-cell homeostasis and antibody responses.
|
Eur J Immunol
|
2011
|
0.98
|
52
|
Alveolar macrophages and lung dendritic cells sense RNA and drive mucosal IgA responses.
|
J Immunol
|
2009
|
0.98
|
53
|
Functional analysis of Ectodysplasin-A mutations causing selective tooth agenesis.
|
Eur J Hum Genet
|
2010
|
0.98
|
54
|
The oncogene metadherin modulates the apoptotic pathway based on the tumor necrosis factor superfamily member TRAIL (Tumor Necrosis Factor-related Apoptosis-inducing Ligand) in breast cancer.
|
J Biol Chem
|
2013
|
0.97
|
55
|
Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by PolyIC in vivo.
|
PLoS One
|
2011
|
0.97
|
56
|
Direct Thy-1/alphaVbeta3 integrin interaction mediates neuron to astrocyte communication.
|
Biochim Biophys Acta
|
2008
|
0.97
|
57
|
Fas ligand-induced proinflammatory transcriptional responses in reconstructed human epidermis. Recruitment of the epidermal growth factor receptor and activation of MAP kinases.
|
J Biol Chem
|
2007
|
0.96
|
58
|
Neonatal treatment with recombinant ectodysplasin prevents respiratory disease in dogs with X-linked ectodermal dysplasia.
|
Am J Med Genet A
|
2009
|
0.96
|
59
|
Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with alphavbeta3 integrin that activates PKCalpha and RhoA.
|
J Cell Sci
|
2009
|
0.95
|
60
|
Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis.
|
Proc Natl Acad Sci U S A
|
2012
|
0.95
|
61
|
Identification of ectodysplasin target genes reveals the involvement of chemokines in hair development.
|
J Invest Dermatol
|
2012
|
0.94
|
62
|
Probing the interaction between feline immunodeficiency virus and CD134 by using the novel monoclonal antibody 7D6 and the CD134 (Ox40) ligand.
|
J Virol
|
2007
|
0.94
|
63
|
Biological activity of ectodysplasin A is conditioned by its collagen and heparan sulfate proteoglycan-binding domains.
|
J Biol Chem
|
2009
|
0.92
|
64
|
Toll-like receptor agonists synergize with CD40L to induce either proliferation or plasma cell differentiation of mouse B cells.
|
PLoS One
|
2011
|
0.92
|
65
|
Cell death-induced activation of epidermal growth factor receptor in keratinocytes: implications for restricting epidermal damage in dermatitis.
|
J Invest Dermatol
|
2005
|
0.91
|
66
|
Induction of the alternative NF-κB pathway by lymphotoxin αβ (LTαβ) relies on internalization of LTβ receptor.
|
Mol Cell Biol
|
2011
|
0.90
|
67
|
RANKL expression, function, and therapeutic targeting in multiple myeloma and chronic lymphocytic leukemia.
|
Cancer Res
|
2012
|
0.90
|
68
|
Chicken BAFF--a highly conserved cytokine that mediates B cell survival.
|
Int Immunol
|
2004
|
0.89
|
69
|
Molecular and therapeutic characterization of anti-ectodysplasin A receptor (EDAR) agonist monoclonal antibodies.
|
J Biol Chem
|
2011
|
0.88
|
70
|
ATP release due to Thy-1-integrin binding induces P2X7-mediated calcium entry required for focal adhesion formation.
|
J Cell Sci
|
2011
|
0.86
|
71
|
Unique and conserved functions of B cell-activating factor of the TNF family (BAFF) in the chicken.
|
Int Immunol
|
2007
|
0.86
|
72
|
Distribution of the human intracellular serpin protease inhibitor 8 in human tissues.
|
J Histochem Cytochem
|
2002
|
0.86
|
73
|
The design and characterization of receptor-selective APRIL variants.
|
J Biol Chem
|
2012
|
0.86
|
74
|
Structure-function analysis of Eiger, the Drosophila TNF homolog.
|
Cell Res
|
2009
|
0.85
|
75
|
Theileria parva-transformed T cells show enhanced resistance to Fas/Fas ligand-induced apoptosis.
|
J Immunol
|
2003
|
0.85
|
76
|
Astrocytic αVβ3 integrin inhibits neurite outgrowth and promotes retraction of neuronal processes by clustering Thy-1.
|
PLoS One
|
2012
|
0.84
|
77
|
Transduction of CpG DNA-stimulated primary human B cells with bicistronic lentivectors.
|
Mol Ther
|
2005
|
0.84
|
78
|
Programming of marginal zone B-cell fate by basic Kruppel-like factor (BKLF/KLF3).
|
Blood
|
2011
|
0.84
|
79
|
Thy-1-mediated cell-cell contact induces astrocyte migration through the engagement of αVβ3 integrin and syndecan-4.
|
Biochim Biophys Acta
|
2013
|
0.83
|
80
|
Cysteine-rich domain 1 of CD40 mediates receptor self-assembly.
|
J Biol Chem
|
2013
|
0.83
|
81
|
The C76R transmembrane activator and calcium modulator cyclophilin ligand interactor mutation disrupts antibody production and B-cell homeostasis in heterozygous and homozygous mice.
|
J Allergy Clin Immunol
|
2011
|
0.82
|
82
|
Receptor activator for NF-κB ligand in acute myeloid leukemia: expression, function, and modulation of NK cell immunosurveillance.
|
J Immunol
|
2012
|
0.81
|
83
|
Effects of fructose-containing caloric sweeteners on resting energy expenditure and energy efficiency: a review of human trials.
|
Nutr Metab (Lond)
|
2013
|
0.80
|
84
|
Rescue of the mature B cell compartment in BAFF-deficient mice by treatment with recombinant Fc-BAFF.
|
Immunol Lett
|
2010
|
0.80
|
85
|
Enforced covalent trimerisation of soluble feline CD134 (OX40)-ligand generates a functional antagonist of feline immunodeficiency virus.
|
Mol Immunol
|
2009
|
0.79
|
86
|
Structure of the extracellular domains of human and Xenopus Fn14: implications in the evolution of TWEAK and Fn14 interactions.
|
FEBS J
|
2013
|
0.78
|
87
|
Generation and characterization of function-blocking anti-ectodysplasin A (EDA) monoclonal antibodies that induce ectodermal dysplasia.
|
J Biol Chem
|
2014
|
0.78
|
88
|
Therapeutic blockade of LIGHT interaction with herpesvirus entry mediator and lymphotoxin β receptor attenuates in vivo cytotoxic allogeneic responses.
|
Transplantation
|
2014
|
0.77
|
89
|
No evidence that soluble TACI induces signalling via membrane-expressed BAFF and APRIL in myeloid cells.
|
PLoS One
|
2013
|
0.77
|
90
|
Buffy's, B cells, and membrane BAFF.
|
Arthritis Rheum
|
2010
|
0.75
|
91
|
Heparan sulfate proteoglycans, Fc receptors, and DC suppression.
|
Blood
|
2008
|
0.75
|
92
|
Rationally-designed multivalent architectures for mimicking homotrimers of CD40L, a member of the TNF superfamily.
|
Adv Exp Med Biol
|
2009
|
0.75
|