Published in Int Immunol on March 01, 2004
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APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa. J Clin Invest (2008) 1.50
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Paucity of clinical disease despite serological autoimmunity and kidney pathology in lupus-prone New Zealand mixed 2328 mice deficient in BAFF. J Immunol (2006) 1.43
BAFF is increased in renal transplant patients following treatment with alemtuzumab. Am J Transplant (2009) 1.06
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Expression of B-cell activating factor enhances protective immunity of a vaccine against Pseudomonas aeruginosa. Infect Immun (2009) 0.91
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Systemic autoimmunity in BAFF-R-mutant A/WySnJ strain mice. Eur J Immunol (2008) 0.90
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BAFF overexpression promotes anti-dsDNA B-cell maturation and antibody secretion. Cell Immunol (2009) 0.87
The current status of targeting BAFF/BLyS for autoimmune diseases. Arthritis Res Ther (2004) 0.87
Increased levels of BAFF and APRIL related to human active pulmonary tuberculosis. PLoS One (2012) 0.85
Enhanced immunogenicity of pneumococcal surface adhesin A (PsaA) in mice via fusion to recombinant human B lymphocyte stimulator (BLyS). Biol Direct (2011) 0.82
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The strength of the antibody response to the nematode Ascaris lumbricoides inversely correlates with levels of B-Cell Activating Factor (BAFF). BMC Immunol (2014) 0.79
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The function of BAFF on T helper cells in autoimmunity. Cytokine Growth Factor Rev (2013) 0.75
Targeting Vaccine-Induced Extrafollicular Pathway of B Cell Differentiation Improves Rabies Postexposure Prophylaxis. J Virol (2017) 0.75
Characterization of BAFF and APRIL subfamily receptors in rainbow trout (Oncorhynchus mykiss). Potential role of the BAFF / APRIL axis in the pathogenesis of proliferative kidney disease. PLoS One (2017) 0.75
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Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature (2006) 24.43
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Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature (2005) 17.47
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science (2008) 16.54
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity (2004) 13.55
A role for mitochondria in NLRP3 inflammasome activation. Nature (2010) 13.21
The inflammasomes: guardians of the body. Annu Rev Immunol (2009) 12.89
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell (2003) 11.07
Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol (2009) 9.24
Intracellular pattern recognition receptors in the host response. Nature (2006) 8.04
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. Cell (2007) 7.74
The inflammasome: a danger sensing complex triggering innate immunity. Curr Opin Immunol (2007) 6.81
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med (2009) 6.73
Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell (2004) 6.06
RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation. Nat Immunol (2004) 5.74
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature (2009) 5.00
Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. Curr Biol (2004) 4.89
BAFF AND APRIL: a tutorial on B cell survival. Annu Rev Immunol (2001) 4.87
A pilot study of IL-1 inhibition by anakinra in acute gout. Arthritis Res Ther (2007) 4.65
Obstetric outcomes after treatment of periodontal disease during pregnancy: systematic review and meta-analysis. BMJ (2010) 4.44
The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress. Science (2004) 4.17
Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome. J Clin Invest (2002) 4.14
NLRs join TLRs as innate sensors of pathogens. Trends Immunol (2005) 4.12
Type I interferon inhibits interleukin-1 production and inflammasome activation. Immunity (2011) 3.97
Cracking the BAFF code. Nat Rev Immunol (2009) 3.95
Toxic epidermal necrolysis and Stevens-Johnson syndrome. Orphanet J Rare Dis (2010) 3.69
Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome. J Immunol (2008) 3.66
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation. Immunity (2012) 3.51
PIDD mediates NF-kappaB activation in response to DNA damage. Cell (2005) 3.48
The molecular architecture of the TNF superfamily. Trends Biochem Sci (2002) 3.39
Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. J Exp Med (2003) 3.24
Toll-like receptors and RNA helicases: two parallel ways to trigger antiviral responses. Mol Cell (2006) 3.23
Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response. J Histochem Cytochem (2006) 3.20
CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kappa B activation. Nat Immunol (2002) 3.16
Telemedical wound care using a new generation of mobile telephones: a feasibility study. Arch Dermatol (2005) 2.91
Infusion of cytomegalovirus (CMV)-specific T cells for the treatment of CMV infection not responding to antiviral chemotherapy. Blood (2002) 2.88
BAFF selectively enhances the survival of plasmablasts generated from human memory B cells. J Clin Invest (2003) 2.87
The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex. J Biol Chem (2002) 2.75
Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human. J Biol Chem (2006) 2.75
Activation of the IL-1beta-processing inflammasome is involved in contact hypersensitivity. J Invest Dermatol (2007) 2.73
TWEAK induces liver progenitor cell proliferation. J Clin Invest (2005) 2.68
A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses. Nat Immunol (2007) 2.68
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes. Nature (2009) 2.59
Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis. Arthritis Rheum (2002) 2.58
The RIP kinases: crucial integrators of cellular stress. Trends Biochem Sci (2005) 2.56
cFLIP regulation of lymphocyte activation and development. Nat Rev Immunol (2006) 2.53
Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex. Mol Cell Biol (2003) 2.50
Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. Am J Respir Crit Care Med (2009) 2.45
Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland. Proc Natl Acad Sci U S A (2010) 2.45
APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells. Blood (2008) 2.44
Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation. Immunity (2003) 2.41
EWS-FLI-1 expression triggers a Ewing's sarcoma initiation program in primary human mesenchymal stem cells. Cancer Res (2008) 2.39
TRADD protein is an essential component of the RIG-like helicase antiviral pathway. Immunity (2008) 2.37
Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction. Immunity (2004) 2.36
Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome. Curr Biol (2009) 2.34
Tollip regulates proinflammatory responses to interleukin-1 and lipopolysaccharide. Mol Cell Biol (2006) 2.33
TL1A-DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease. J Exp Med (2008) 2.33
Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses. Nat Immunol (2008) 2.32
Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome. PLoS Pathog (2009) 2.24
NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain. Structure (2003) 2.15
TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha. J Cell Biol (2008) 2.11
N-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kappaB signaling pathway. Mol Cell Biol (2004) 2.11
Progesterone/RANKL is a major regulatory axis in the human breast. Sci Transl Med (2013) 2.09
Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β. Proc Natl Acad Sci U S A (2010) 2.09
BAFF, APRIL and their receptors: structure, function and signaling. Semin Immunol (2006) 2.09
Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4. Proc Natl Acad Sci U S A (2009) 2.04
Identification of proteoglycans as the APRIL-specific binding partners. J Exp Med (2005) 2.03
Caspase-independent cell death in T lymphocytes. Nat Immunol (2003) 1.99
Negative direct immunofluorescence and nonspecific histology do not exclude the diagnosis of dermatitis herpetiformis Duhring. Int J Dermatol (2013) 1.98
Treatment of toxic epidermal necrolysis with high-dose intravenous immunoglobulins: multicenter retrospective analysis of 48 consecutive cases. Arch Dermatol (2003) 1.95
NALP inflammasomes: a central role in innate immunity. Semin Immunopathol (2007) 1.91
Type I IFN controls chikungunya virus via its action on nonhematopoietic cells. J Exp Med (2010) 1.86
TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts. Blood (2007) 1.85
Recommendations from an international consensus conference on the current status and future of neoadjuvant systemic therapy in primary breast cancer. Ann Surg Oncol (2011) 1.83
Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions. Blood (2003) 1.78
Permanent correction of an inherited ectodermal dysplasia with recombinant EDA. Nat Med (2003) 1.75
Human NK cells can control CMV infection in the absence of T cells. Blood (2008) 1.75
Caspase-2 activation in the absence of PIDDosome formation. J Cell Biol (2009) 1.74
Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway. EMBO J (2006) 1.74
TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration. EMBO J (2006) 1.73
DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB. EMBO Rep (2009) 1.72
Generation of the primary hair follicle pattern. Proc Natl Acad Sci U S A (2006) 1.72
IL-31 expression by inflammatory cells is preferentially elevated in atopic dermatitis. Acta Derm Venereol (2012) 1.66
NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth. Development (2006) 1.66
Myc-transformed epithelial cells down-regulate clusterin, which inhibits their growth in vitro and carcinogenesis in vivo. Cancer Res (2004) 1.65
Efficient generation of human alloantigen-specific CD4+ regulatory T cells from naive precursors by CD40-activated B cells. Blood (2008) 1.64
Fas ligand elicits a caspase-independent proinflammatory response in human keratinocytes: implications for dermatitis. J Invest Dermatol (2006) 1.64
NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8⁺ T cells. Nat Immunol (2012) 1.62
Differential expression of NLRP3 among hematopoietic cells. J Immunol (2011) 1.60