Published in Reproduction on April 01, 2004
Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene. Proc Natl Acad Sci U S A (2007) 2.66
Cyclin A is redundant in fibroblasts but essential in hematopoietic and embryonic stem cells. Cell (2009) 2.05
The cyclin A1-CDK2 complex regulates DNA double-strand break repair. Mol Cell Biol (2004) 1.43
Cyclin A1-deficient mice lack histone H3 serine 10 phosphorylation and exhibit altered aurora B dynamics in late prophase of male meiosis. Dev Biol (2007) 1.10
Cyclin A1 promoter hypermethylation in human papillomavirus-associated cervical cancer. BMC Cancer (2006) 1.04
Regulating mitosis and meiosis in the male germ line: critical functions for cyclins. Philos Trans R Soc Lond B Biol Sci (2010) 0.95
Function of cyclins in regulating the mitotic and meiotic cell cycles in male germ cells. Cell Cycle (2008) 0.89
Pituitary gland development and disease: from stem cell to hormone production. Curr Top Dev Biol (2013) 0.88
Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J Med Chem (2013) 0.85
Function of the A-type cyclins during gametogenesis and early embryogenesis. Results Probl Cell Differ (2011) 0.81
Lhx4 deficiency: increased cyclin-dependent kinase inhibitor expression and pituitary hypoplasia. Mol Endocrinol (2015) 0.77
Altered expression of cyclin A 1 in muscle of patients with facioscapulohumeral muscle dystrophy (FSHD-1). PLoS One (2013) 0.76
A Limited Role for the Cell Cycle Regulator Cyclin A1 in Murine Leukemogenesis. PLoS One (2015) 0.75
The genome of the African trypanosome Trypanosoma brucei. Science (2005) 11.48
The GPR54 gene as a regulator of puberty. N Engl J Med (2003) 9.54
The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. Science (2005) 7.61
Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54. Proc Natl Acad Sci U S A (2005) 3.79
TriTrypDB: a functional genomic resource for the Trypanosomatidae. Nucleic Acids Res (2009) 3.79
Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a. Proc Natl Acad Sci U S A (2002) 3.59
Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene. Proc Natl Acad Sci U S A (2007) 2.66
Synthetic chemerin-derived peptides suppress inflammation through ChemR23. J Exp Med (2008) 2.54
Sleeping sickness in Uganda: a thin line between two fatal diseases. BMJ (2005) 2.53
Kisspeptin-GPR54 signaling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge. J Neurosci (2008) 2.38
Stella is a maternal effect gene required for normal early development in mice. Curr Biol (2003) 2.38
Aminoglycoside suppression of a premature stop mutation in a Cftr-/- mouse carrying a human CFTR-G542X transgene. J Mol Med (Berl) (2002) 2.34
The trypanosome flagellar pocket. Nat Rev Microbiol (2009) 2.07
Functional genomics in Trypanosoma brucei: a collection of vectors for the expression of tagged proteins from endogenous and ectopic gene loci. Mol Biochem Parasitol (2007) 1.96
GeneDB--an annotation database for pathogens. Nucleic Acids Res (2011) 1.82
Murine Models for Trypanosoma brucei gambiense disease progression--from silent to chronic infections and early brain tropism. PLoS Negl Trop Dis (2009) 1.79
The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform. Diabetes (2005) 1.76
Impaired impulse propagation in Scn5a-knockout mice: combined contribution of excitability, connexin expression, and tissue architecture in relation to aging. Circulation (2005) 1.74
Mouse model of SCN5A-linked hereditary Lenègre's disease: age-related conduction slowing and myocardial fibrosis. Circulation (2005) 1.69
Kisspeptin can stimulate gonadotropin-releasing hormone (GnRH) release by a direct action at GnRH nerve terminals. Endocrinology (2008) 1.66
Heat shock causes a decrease in polysomes and the appearance of stress granules in trypanosomes independently of eIF2(alpha) phosphorylation at Thr169. J Cell Sci (2008) 1.64
Mouse models of cystic fibrosis: phenotypic analysis and research applications. J Cyst Fibros (2011) 1.61
The heart of darkness: growth and form of Trypanosoma brucei in the tsetse fly. Trends Parasitol (2009) 1.54
Innate BALB/c enteric epithelial responses to Trichinella spiralis: inducible expression of a novel goblet cell lectin, intelectin-2, and its natural deletion in C57BL/10 mice. J Immunol (2004) 1.47
Chromosome-wide analysis of gene function by RNA interference in the african trypanosome. Eukaryot Cell (2006) 1.47
A role for Caf1 in mRNA deadenylation and decay in trypanosomes and human cells. Nucleic Acids Res (2008) 1.46
Asymmetric cell division as a route to reduction in cell length and change in cell morphology in trypanosomes. Protist (2007) 1.43
The cyclin A1-CDK2 complex regulates DNA double-strand break repair. Mol Cell Biol (2004) 1.43
Distribution and postnatal development of Gpr54 gene expression in mouse brain and gonadotropin-releasing hormone neurons. Endocrinology (2009) 1.40
Hydrodynamic gene delivery of baboon trypanosome lytic factor eliminates both animal and human-infective African trypanosomes. Proc Natl Acad Sci U S A (2009) 1.38
Identification of the meiotic life cycle stage of Trypanosoma brucei in the tsetse fly. Proc Natl Acad Sci U S A (2011) 1.31
Trans-acting proteins regulating mRNA maturation, stability and translation in trypanosomatids. Trends Parasitol (2010) 1.27
Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a. J Physiol (2005) 1.27
Variable Na(v)1.5 protein expression from the wild-type allele correlates with the penetrance of cardiac conduction disease in the Scn5a(+/-) mouse model. PLoS One (2010) 1.26
Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/- murine hearts modelling the Brugada syndrome. J Physiol (2007) 1.19
Involvement of the anion exchanger SLC26A6 in prostaglandin E2- but not forskolin-stimulated duodenal HCO3- secretion. Gastroenterology (2006) 1.17
Variant Surface Glycoprotein gene repertoires in Trypanosoma brucei have diverged to become strain-specific. BMC Genomics (2007) 1.15
The VSG C-terminal domain is inaccessible to antibodies on live trypanosomes. Mol Biochem Parasitol (2010) 1.15
A multiplex PCR that discriminates between Trypanosoma brucei brucei and zoonotic T. b. rhodesiense. Exp Parasitol (2007) 1.14
Intracellular membrane transport systems in Trypanosoma brucei. Traffic (2004) 1.13
The kinetoplastida endocytic apparatus. Part I: a dynamic system for nutrition and evasion of host defences. Trends Parasitol (2002) 1.12
Binding of (-)-[3H]-CGP12177 at two sites in recombinant human beta 1-adrenoceptors and interaction with beta-blockers. Naunyn Schmiedebergs Arch Pharmacol (2004) 1.12
Bloodstream form Trypanosome plasma membrane proteins: antigenic variation and invariant antigens. Parasitology (2010) 1.11
Paced electrogram fractionation analysis of arrhythmogenic tendency in DeltaKPQ Scn5a mice. J Cardiovasc Electrophysiol (2005) 1.10
The origin of the serum resistance associated (SRA) gene and a model of the structure of the SRA polypeptide from Trypanosoma brucei rhodesiense. Mol Biochem Parasitol (2003) 1.09
The RNA helicase DHH1 is central to the correct expression of many developmentally regulated mRNAs in trypanosomes. J Cell Sci (2010) 1.06
The orphan adhesion-GPCR GPR126 is required for embryonic development in the mouse. PLoS One (2010) 1.06
Structure of the trypanosome haptoglobin-hemoglobin receptor and implications for nutrient uptake and innate immunity. Proc Natl Acad Sci U S A (2013) 1.06
Effects of L-type Ca2+ channel antagonism on ventricular arrhythmogenesis in murine hearts containing a modification in the Scn5a gene modelling human long QT syndrome 3. J Physiol (2006) 1.05
Ubiquitylation is required for degradation of transmembrane surface proteins in trypanosomes. Traffic (2008) 1.05
DeltaF508-CFTR causes constitutive NF-kappaB activation through an ER-overload response in cystic fibrosis lungs. Biol Chem (2002) 1.05
Small trypanosome RNA-binding proteins TbUBP1 and TbUBP2 influence expression of F-box protein mRNAs in bloodstream trypanosomes. Eukaryot Cell (2007) 1.05
The endocytic apparatus of the kinetoplastida. Part II: machinery and components of the system. Trends Parasitol (2002) 1.05
On the accuracy of a moving average algorithm for target tracking during radiation therapy treatment delivery. Med Phys (2008) 1.04
Proteomic selection of immunodiagnostic antigens for human African trypanosomiasis and generation of a prototype lateral flow immunodiagnostic device. PLoS Negl Trop Dis (2013) 1.04
Frequency-dependent recruitment of fast amino acid and slow neuropeptide neurotransmitter release controls gonadotropin-releasing hormone neuron excitability. J Neurosci (2011) 1.04
Cytoplasmic targeting signals in transmembrane invariant surface glycoproteins of trypanosomes. J Biol Chem (2004) 1.03
Ubiquitylation and developmental regulation of invariant surface protein expression in trypanosomes. Eukaryot Cell (2011) 1.03
Developmentally regulated instability of the GPI-PLC mRNA is dependent on a short-lived protein factor. Nucleic Acids Res (2005) 1.03
Structure of the C-terminal domain from Trypanosoma brucei variant surface glycoprotein MITat1.2. J Biol Chem (2004) 1.01
Intrinsic sympathomimetic activity of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta1-adrenoceptor in human atrium and recombinant receptors. Naunyn Schmiedebergs Arch Pharmacol (2003) 1.00
The four trypanosomatid eIF4E homologues fall into two separate groups, with distinct features in primary sequence and biological properties. Mol Biochem Parasitol (2010) 0.99
Clinical evaluation of soft tissue organ boundary visualization on cone-beam computed tomographic imaging. Int J Radiat Oncol Biol Phys (2010) 0.99
Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/Delta murine hearts modelling long QT syndrome 3. J Physiol (2006) 0.98
Genome-wide in silico screen for CCCH-type zinc finger proteins of Trypanosoma brucei, Trypanosoma cruzi and Leishmania major. BMC Genomics (2010) 0.98
The two eIF4A helicases in Trypanosoma brucei are functionally distinct. Nucleic Acids Res (2006) 0.98
Kisspeptin signaling is required for peripheral but not central stimulation of gonadotropin-releasing hormone neurons by NMDA. J Neurosci (2010) 0.98
A new generation of T7 RNA polymerase-independent inducible expression plasmids for Trypanosoma brucei. PLoS One (2012) 0.98
Whole-genome analysis of animal A- and B-type cyclins. Genome Biol (2002) 0.97
Murine model of autosomal dominant retinitis pigmentosa generated by targeted deletion at codon 307 of the rds-peripherin gene. Hum Mol Genet (2002) 0.96
International Union of Basic and Clinical Pharmacology. LXXVII. Kisspeptin receptor nomenclature, distribution, and function. Pharmacol Rev (2010) 0.95
Kisspeptin-GPR54 signaling in mouse NO-synthesizing neurons participates in the hypothalamic control of ovulation. J Neurosci (2012) 0.95
Blocking variant surface glycoprotein synthesis in Trypanosoma brucei triggers a general arrest in translation initiation. PLoS One (2009) 0.94
VSG structure: similar N-terminal domains can form functional VSGs with different types of C-terminal domain. Mol Biochem Parasitol (2003) 0.92
Splenomegaly and modified erythropoiesis in KLF13-/- mice. J Biol Chem (2008) 0.92
Characterization and functional study of a cluster of four highly conserved orphan adhesion-GPCR in mouse. Dev Dyn (2012) 0.92
VSGdb: a database for trypanosome variant surface glycoproteins, a large and diverse family of coiled coil proteins. BMC Bioinformatics (2007) 0.91
Functional characterization of three leishmania poly(a) binding protein homologues with distinct binding properties to RNA and protein partners. Eukaryot Cell (2010) 0.91
Chaperone requirements for biosynthesis of the trypanosome variant surface glycoprotein. PLoS One (2010) 0.90
Functional characterization of cohesin subunit SCC1 in Trypanosoma brucei and dissection of mutant phenotypes in two life cycle stages. Mol Microbiol (2008) 0.90
Inhibition of mRNA maturation in trypanosomes causes the formation of novel foci at the nuclear periphery containing cytoplasmic regulators of mRNA fate. J Cell Sci (2012) 0.90
How do trypanosomes change gene expression in response to the environment? Protoplasma (2011) 0.90
A role for the vesicle-associated tubulin binding protein ARL6 (BBS3) in flagellum extension in Trypanosoma brucei. Biochim Biophys Acta (2012) 0.89
The glycosylphosphatidylinositol-PLC in Trypanosoma brucei forms a linear array on the exterior of the flagellar membrane before and after activation. PLoS Pathog (2009) 0.89
Mll5 is required for normal spermatogenesis. PLoS One (2011) 0.89
Is there a classical nonsense-mediated decay pathway in trypanosomes? PLoS One (2011) 0.88
Comparison of protein transduction domains in mediating cell delivery of a secreted CRE protein. Biochemistry (2008) 0.87
Candidate protein selection for diagnostic markers of African trypanosomiasis. Trends Parasitol (2004) 0.87
Kisspeptin neurons co-express met-enkephalin and galanin in the rostral periventricular region of the female mouse hypothalamus. J Comp Neurol (2011) 0.86
Locating and targeting moving tumors with radiation beams. Med Phys (2008) 0.86
The orthologue of Sjögren's syndrome nuclear autoantigen 1 (SSNA1) in Trypanosoma brucei is an immunogenic self-assembling molecule. PLoS One (2012) 0.85
Sequence variation and structural conservation allows development of novel function and immune evasion in parasite surface protein families. Protein Sci (2014) 0.85
The Ontology for Parasite Lifecycle (OPL): towards a consistent vocabulary of lifecycle stages in parasitic organisms. J Biomed Semantics (2012) 0.85
Gpr54-/- mice show more pronounced defects in spermatogenesis than Kiss1-/- mice and improved spermatogenesis with age when exposed to dietary phytoestrogens. Reproduction (2010) 0.85
Structure of a glycosylphosphatidylinositol-anchored domain from a trypanosome variant surface glycoprotein. J Biol Chem (2007) 0.85
Yeast-based automated high-throughput screens to identify anti-parasitic lead compounds. Open Biol (2013) 0.85
Differential localization of the two T. brucei poly(A) binding proteins to the nucleus and RNP granules suggests binding to distinct mRNA pools. PLoS One (2013) 0.84
X-ray microanalysis of airway surface liquid in the mouse. Am J Physiol Lung Cell Mol Physiol (2004) 0.83