Published in Endocrinology on May 01, 2008
Kisspeptin signaling in the brain. Endocr Rev (2009) 2.83
Regulation of gonadotropin-releasing hormone secretion by kisspeptin/dynorphin/neurokinin B neurons in the arcuate nucleus of the mouse. J Neurosci (2009) 2.78
Neurokinin B stimulates GnRH release in the male monkey (Macaca mulatta) and is colocalized with kisspeptin in the arcuate nucleus. Endocrinology (2010) 2.40
Minireview: kisspeptin/neurokinin B/dynorphin (KNDy) cells of the arcuate nucleus: a central node in the control of gonadotropin-releasing hormone secretion. Endocrinology (2010) 2.23
Hyperprolactinemia-induced ovarian acyclicity is reversed by kisspeptin administration. J Clin Invest (2012) 1.53
Neurokinin B and the hypothalamic regulation of reproduction. Brain Res (2010) 1.46
Kisspeptin signalling in the hypothalamic arcuate nucleus regulates GnRH pulse generator frequency in the rat. PLoS One (2009) 1.42
Kisspeptin-10, a KISS1-derived decapeptide, inhibits tumor angiogenesis by suppressing Sp1-mediated VEGF expression and FAK/Rho GTPase activation. Cancer Res (2009) 1.21
Coming of age in the kisspeptin era: sex differences, development, and puberty. Mol Cell Endocrinol (2010) 1.17
Neuroendocrine control by kisspeptins: role in metabolic regulation of fertility. Nat Rev Endocrinol (2011) 1.17
Kisspeptin-10 facilitates a plasma membrane-driven calcium oscillator in gonadotropin-releasing hormone-1 neurons. Endocrinology (2008) 1.16
Anatomy of the kisspeptin neural network in mammals. Brain Res (2010) 1.09
New insights into the control of pulsatile GnRH release: the role of Kiss1/neurokinin B neurons. Front Endocrinol (Lausanne) (2012) 1.09
The excitatory peptide kisspeptin restores the luteinizing hormone surge and modulates amino acid neurotransmission in the medial preoptic area of middle-aged rats. Endocrinology (2009) 1.07
Disrupted kisspeptin signaling in GnRH neurons leads to hypogonadotrophic hypogonadism. Mol Endocrinol (2014) 1.05
Kisspeptin resets the hypothalamic GnRH clock in men. J Clin Endocrinol Metab (2011) 1.05
Circadian control of neuroendocrine circuits regulating female reproductive function. Front Endocrinol (Lausanne) (2012) 1.03
Kisspeptin increases GnRH mRNA expression and secretion in GnRH secreting neuronal cell lines. Mol Cell Endocrinol (2009) 1.01
Estrogenic regulation of the GnRH neuron. Front Endocrinol (Lausanne) (2012) 1.00
Estradiol signaling in the regulation of reproduction and energy balance. Front Neuroendocrinol (2012) 0.99
The Neurosteroid Progesterone Underlies Estrogen Positive Feedback of the LH Surge. Front Endocrinol (Lausanne) (2011) 0.97
International Union of Basic and Clinical Pharmacology. LXXVII. Kisspeptin receptor nomenclature, distribution, and function. Pharmacol Rev (2010) 0.95
Neuroanatomy of the kisspeptin signaling system in mammals: comparative and developmental aspects. Adv Exp Med Biol (2013) 0.94
Low degree of overlap between kisspeptin, neurokinin B, and dynorphin immunoreactivities in the infundibular nucleus of young male human subjects challenges the KNDy neuron concept. Endocrinology (2012) 0.93
Interactions between kisspeptins and neurokinin B. Adv Exp Med Biol (2013) 0.91
Differential regulation of GnRH secretion in the preoptic area (POA) and the median eminence (ME) in male mice. Endocrinology (2015) 0.90
Neuroendocrine control of the transition to reproductive senescence: lessons learned from the female rodent model. Neuroendocrinology (2012) 0.90
Regulation of embryonic kidney branching morphogenesis and glomerular development by KISS1 receptor (Gpr54) through NFAT2- and Sp1-mediated Bmp7 expression. J Biol Chem (2010) 0.89
Impaired GABAB receptor signaling dramatically up-regulates Kiss1 expression selectively in nonhypothalamic brain regions of adult but not prepubertal mice. Endocrinology (2013) 0.89
Cross-Talk between Metabolism and Reproduction: The Role of POMC and SF1 Neurons. Front Endocrinol (Lausanne) (2012) 0.88
Activation of neurokinin 3 receptors stimulates GnRH release in a location-dependent but kisspeptin-independent manner in adult mice. Endocrinology (2013) 0.88
Kisspeptins and RFRP-3 Act in Concert to Synchronize Rodent Reproduction with Seasons. Front Neurosci (2013) 0.86
Organizational and activational effects of sex steroids on kisspeptin neuron development. Front Neuroendocrinol (2012) 0.86
Hypothalamic molecular changes underlying natural reproductive senescence in the female rat. Endocrinology (2014) 0.85
Kisspeptin signaling is required for the luteinizing hormone response in anestrous ewes following the introduction of males. PLoS One (2013) 0.84
Increasing LH pulsatility in women with hypothalamic amenorrhoea using intravenous infusion of Kisspeptin-54. J Clin Endocrinol Metab (2014) 0.83
Selective optogenetic activation of arcuate kisspeptin neurons generates pulsatile luteinizing hormone secretion. Proc Natl Acad Sci U S A (2015) 0.82
Unpredictable chronic stress-induced reproductive suppression associated with the decrease of kisspeptin immunoreactivity in male mice. J Vet Med Sci (2014) 0.81
Single-cell analyses reveal that KISS1R-expressing cells undergo sustained kisspeptin-induced signaling that is dependent upon an influx of extracellular Ca2+. Endocrinology (2012) 0.81
Twice-daily subcutaneous injection of kisspeptin-54 does not abolish menstrual cyclicity in healthy female volunteers. J Clin Endocrinol Metab (2013) 0.80
Effects of full-length kisspeptin administration on follicular development in Japanese Black beef cows. J Reprod Dev (2013) 0.80
Leap of Faith: Does Serum Luteinizing Hormone Always Accurately Reflect Central Reproductive Neuroendocrine Activity? Neuroendocrinology (2015) 0.80
A Multi-Oscillatory Circadian System Times Female Reproduction. Front Endocrinol (Lausanne) (2015) 0.79
Afferent neuronal control of type-I gonadotropin releasing hormone neurons in the human. Front Endocrinol (Lausanne) (2013) 0.79
Comprehensive Review on Kisspeptin and Its Role in Reproductive Disorders. Endocrinol Metab (Seoul) (2015) 0.79
Kisspeptins modulate the biology of multiple populations of gonadotropin-releasing hormone neurons during embryogenesis and adulthood in zebrafish (Danio rerio). PLoS One (2014) 0.78
Differential effects of continuous exposure to the investigational metastin/kisspeptin analog TAK-683 on pulsatile and surge mode secretion of luteinizing hormone in ovariectomized goats. J Reprod Dev (2013) 0.78
A synthetic kisspeptin analog that triggers ovulation and advances puberty. Sci Rep (2016) 0.77
KISS1 gene expression in the developing brain of female pigs in pre- and peripubertal periods. J Reprod Dev (2014) 0.77
Prolonged infusion of estradiol benzoate into the stalk median eminence stimulates release of GnRH and kisspeptin in ovariectomized female rhesus macaques. Endocrinology (2015) 0.77
Kisspeptin receptor agonist (FTM080) increased plasma concentrations of luteinizing hormone in anestrous ewes. PeerJ (2015) 0.77
Galanin Activates G Protein Gated Inwardly Rectifying Potassium Channels and Suppresses Kisspeptin-10 Activation of GnRH Neurons. Endocrinology (2016) 0.76
Distribution and regulation of gonadotropin-releasing hormone, kisspeptin, RF-amide related peptide-3, and dynorphin in the bovine hypothalamus. PeerJ (2016) 0.76
Kisspeptin Regulation of Neuronal Activity throughout the Central Nervous System. Endocrinol Metab (Seoul) (2016) 0.76
Kisspeptin modulates sexual and emotional brain processing in humans. J Clin Invest (2017) 0.75
Using kisspeptin to assess GnRH function in an unusual case of primary amenorrhoea. Endocrinol Diabetes Metab Case Rep (2017) 0.75
EP24.15 as a Potential Regulator of Kisspeptin Within the Neuroendocrine Hypothalamus. Endocrinology (2015) 0.75
Unilaterally blocking the muscarinic receptors in the suprachiasmatic nucleus in proestrus rats prevents pre-ovulatory LH secretion and ovulation. Reprod Biol Endocrinol (2016) 0.75
Effect of the Camelid's Seminal Plasma Ovulation-Inducing Factor/β-NGF: A Kisspeptin Target Hypothesis. Front Vet Sci (2017) 0.75
The GPR54 gene as a regulator of puberty. N Engl J Med (2003) 9.54
The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J Biol Chem (2001) 4.77
Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor. Nature (2001) 4.55
A role for kisspeptins in the regulation of gonadotropin secretion in the mouse. Endocrinology (2004) 4.24
Activation of gonadotropin-releasing hormone neurons by kisspeptin as a neuroendocrine switch for the onset of puberty. J Neurosci (2005) 4.04
Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54. Proc Natl Acad Sci U S A (2005) 3.79
Kisspeptin activation of gonadotropin releasing hormone neurons and regulation of KiSS-1 mRNA in the male rat. Neuroendocrinology (2005) 3.52
Increased hypothalamic GPR54 signaling: a potential mechanism for initiation of puberty in primates. Proc Natl Acad Sci U S A (2005) 3.16
Kisspeptin-54 stimulates the hypothalamic-pituitary gonadal axis in human males. J Clin Endocrinol Metab (2005) 3.08
Postnatal development of kisspeptin neurons in mouse hypothalamus; sexual dimorphism and projections to gonadotropin-releasing hormone neurons. Endocrinology (2006) 2.95
Kiss1-/- mice exhibit more variable hypogonadism than Gpr54-/- mice. Endocrinology (2007) 2.75
Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene. Proc Natl Acad Sci U S A (2007) 2.66
Peripheral administration of metastin induces marked gonadotropin release and ovulation in the rat. Biochem Biophys Res Commun (2004) 2.55
Central and peripheral administration of kisspeptin-10 stimulates the hypothalamic-pituitary-gonadal axis. J Neuroendocrinol (2004) 2.27
Effects of KiSS-1 peptide, the natural ligand of GPR54, on follicle-stimulating hormone secretion in the rat. Endocrinology (2005) 2.23
The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis. Int J Obes Relat Metab Disord (2001) 2.08
Kisspeptin immunoreactive cells of the ovine preoptic area and arcuate nucleus co-express estrogen receptor alpha. Neurosci Lett (2006) 1.98
Characterization of the potent luteinizing hormone-releasing activity of KiSS-1 peptide, the natural ligand of GPR54. Endocrinology (2004) 1.97
Repetitive activation of hypothalamic G protein-coupled receptor 54 with intravenous pulses of kisspeptin in the juvenile monkey (Macaca mulatta) elicits a sustained train of gonadotropin-releasing hormone discharges. Endocrinology (2005) 1.81
Multimodal influence of estrogen upon gonadotropin-releasing hormone neurons. Endocr Rev (1998) 1.73
Effect of continuous intravenous administration of human metastin 45-54 on the neuroendocrine activity of the hypothalamic-pituitary-testicular axis in the adult male rhesus monkey (Macaca mulatta). Endocrinology (2007) 1.33
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Administration of kisspeptin-54 into discrete regions of the hypothalamus potently increases plasma luteinising hormone and testosterone in male adult rats. J Neuroendocrinol (2006) 1.04
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Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a. Proc Natl Acad Sci U S A (2002) 3.59
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Synthetic chemerin-derived peptides suppress inflammation through ChemR23. J Exp Med (2008) 2.54
Kisspeptin-GPR54 signaling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge. J Neurosci (2008) 2.38
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Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a. J Physiol (2005) 1.27
Variable Na(v)1.5 protein expression from the wild-type allele correlates with the penetrance of cardiac conduction disease in the Scn5a(+/-) mouse model. PLoS One (2010) 1.26
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Cyclin A1 protein shows haplo-insufficiency for normal fertility in male mice. Reproduction (2004) 1.03
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Kisspeptin signaling is required for peripheral but not central stimulation of gonadotropin-releasing hormone neurons by NMDA. J Neurosci (2010) 0.98
Murine model of autosomal dominant retinitis pigmentosa generated by targeted deletion at codon 307 of the rds-peripherin gene. Hum Mol Genet (2002) 0.96
Kisspeptin-GPR54 signaling in mouse NO-synthesizing neurons participates in the hypothalamic control of ovulation. J Neurosci (2012) 0.95
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Splenomegaly and modified erythropoiesis in KLF13-/- mice. J Biol Chem (2008) 0.92
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Mll5 is required for normal spermatogenesis. PLoS One (2011) 0.89
Comparison of protein transduction domains in mediating cell delivery of a secreted CRE protein. Biochemistry (2008) 0.87
Kisspeptin neurons co-express met-enkephalin and galanin in the rostral periventricular region of the female mouse hypothalamus. J Comp Neurol (2011) 0.86
The choreography of multidrug export. Biochem Soc Trans (2011) 0.86
Molecular disruption of the power stroke in the ATP-binding cassette transport protein MsbA. J Biol Chem (2013) 0.85
Gpr54-/- mice show more pronounced defects in spermatogenesis than Kiss1-/- mice and improved spermatogenesis with age when exposed to dietary phytoestrogens. Reproduction (2010) 0.85
X-ray microanalysis of airway surface liquid in the mouse. Am J Physiol Lung Cell Mol Physiol (2004) 0.83
The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent. BMC Genomics (2011) 0.82
Ducts isolated from the pancreas of CFTR-null mice secrete fluid. Pflugers Arch (2009) 0.82
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Enhancement of gene delivery to human airway epithelial cells in vitro using a peptide from the polyoma virus protein VP1. J Gene Med (2005) 0.78
Inotropic action of the puberty hormone kisspeptin in rat, mouse and human: cardiovascular distribution and characteristics of the kisspeptin receptor. PLoS One (2011) 0.77
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Defective formation of PKA/CnA-dependent annexin 2-S100A10/CFTR complex in DeltaF508 cystic fibrosis cells. Cell Signal (2008) 0.77
Hyperalgesic activity of kisspeptin in mice. Mol Pain (2011) 0.76
Voltage dependence of the Ca(2+)-activated K(+) channel K(Ca)3.1 in human erythroleukemia cells. Am J Physiol Cell Physiol (2013) 0.76
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