Published in Intensive Care Med on April 07, 2004
Exploring mechanisms of excess mortality with early fluid resuscitation: insights from the FEAST trial. BMC Med (2013) 1.57
Preload-independent mechanisms contribute to increased stroke volume following large volume saline infusion in normal volunteers: a prospective interventional study. Crit Care (2004) 0.92
Saline volume expansion and cardiovascular physiology: novel observations, old explanations, and new questions. Crit Care (2004) 0.81
Rapid intravenous infusion of 20 mL/kg saline alters the distribution of perfusion in healthy supine humans. Respir Physiol Neurobiol (2011) 0.78
Hypovolemia explains the reduced stroke volume at altitude. Physiol Rep (2013) 0.77
Evaluation of left ventricular performance: an insolvable problem in human beings? The Graal quest. Intensive Care Med (2004) 0.75
Relationship between stroke volume and pulse pressure during blood volume perturbation: a mathematical analysis. Biomed Res Int (2014) 0.75
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med (2006) 23.62
Translating research to clinical practice: a 1-year experience with implementing early goal-directed therapy for septic shock in the emergency department. Chest (2006) 5.31
Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock. Chest (2009) 4.51
Association between arterial hyperoxia following resuscitation from cardiac arrest and in-hospital mortality. JAMA (2010) 4.37
Antimicrobial treatment in diabetic women with asymptomatic bacteriuria. N Engl J Med (2002) 4.09
Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: relationship to hemodynamics, oxygen transport, and survival. Ann Emerg Med (2006) 3.36
Early increases in microcirculatory perfusion during protocol-directed resuscitation are associated with reduced multi-organ failure at 24 h in patients with sepsis. Intensive Care Med (2008) 3.14
A population-based case control study of potential risk factors for IBD. Am J Gastroenterol (2006) 2.91
A randomized, double-blind, placebo-controlled, Phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation. Crit Care Med (2013) 2.68
Significance of arterial hypotension after resuscitation from cardiac arrest. Crit Care Med (2009) 2.68
Relationship between supranormal oxygen tension and outcome after resuscitation from cardiac arrest. Circulation (2011) 2.65
Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis. Shock (2009) 2.59
Pulmonary artery occlusion pressure and central venous pressure fail to predict ventricular filling volume, cardiac performance, or the response to volume infusion in normal subjects. Crit Care Med (2004) 2.35
Utility of history, physical examination, electrocardiogram, and chest radiograph for differentiating normal from decreased systolic function in patients with heart failure. Am J Med (2002) 2.34
Validity of a prescription claims database to estimate medication adherence in older persons. Med Care (2006) 2.06
Testing objective measures of motor impairment in early Parkinson's disease: Feasibility study of an at-home testing device. Mov Disord (2009) 2.00
Acute kidney injury in septic shock: clinical outcomes and impact of duration of hypotension prior to initiation of antimicrobial therapy. Intensive Care Med (2008) 1.93
Serum lactate as a predictor of mortality in patients with infection. Intensive Care Med (2007) 1.88
Clinical review: Myocardial depression in sepsis and septic shock. Crit Care (2002) 1.74
Interaction between fluids and vasoactive agents on mortality in septic shock: a multicenter, observational study. Crit Care Med (2014) 1.72
A prospective population-based study of triggers of symptomatic flares in IBD. Am J Gastroenterol (2010) 1.72
Variable ventilation improves perioperative lung function in patients undergoing abdominal aortic aneurysmectomy. Anesthesiology (2004) 1.65
Resuscitating the microcirculation in sepsis: the central role of nitric oxide, emerging concepts for novel therapies, and challenges for clinical trials. Acad Emerg Med (2008) 1.61
Disease course and outcome of juvenile rheumatoid arthritis in a multicenter cohort. J Rheumatol (2002) 1.59
Myocardial dysfunction in the patient with sepsis. Curr Opin Crit Care (2002) 1.47
Use of a standardized order set for achieving target temperature in the implementation of therapeutic hypothermia after cardiac arrest: a feasibility study. Acad Emerg Med (2008) 1.46
Multidisciplinary treatment of diabetic foot ulcers in Canadian Aboriginal and non-Aboriginal people. Foot Ankle Surg (2007) 1.46
Familial seropositive rheumatoid arthritis in North American Native families: effects of shared epitope and cytokine genotypes. J Rheumatol (2005) 1.44
Randomized controlled trial of inhaled nitric oxide for the treatment of microcirculatory dysfunction in patients with sepsis*. Crit Care Med (2014) 1.42
Type 2 diabetes mellitus in children: prenatal and early infancy risk factors among native canadians. Arch Pediatr Adolesc Med (2002) 1.41
Regional distribution of acoustic-based lung vibration as a function of mechanical ventilation mode. Crit Care (2007) 1.36
Clinical characteristics and outcomes of septic patients with new-onset atrial fibrillation. J Crit Care (2008) 1.35
Eosinophilic myocarditis. Heart Fail Clin (2005) 1.34
Protective effect of a novel, potent inhibitor of poly(adenosine 5'-diphosphate-ribose) synthetase in a porcine model of severe bacterial sepsis. Crit Care Med (2002) 1.32
Clinical characteristics, sepsis interventions and outcomes in the obese patients with septic shock: an international multicenter cohort study. Crit Care (2013) 1.31
CDC/AHA Workshop on Markers of Inflammation and Cardiovascular Disease: Application to Clinical and Public Health Practice: report from the clinical practice discussion group. Circulation (2004) 1.25
Dynamic visualization of lung sounds with a vibration response device: a case series. Respiration (2007) 1.24
Vasopressor and inotropic support in septic shock: an evidence-based review. Crit Care Med (2004) 1.23
Adiposopathy: how do diet, exercise and weight loss drug therapies improve metabolic disease in overweight patients? Expert Rev Cardiovasc Ther (2006) 1.23
Treatment of AIDS-associated Kaposi's sarcoma in Zimbabwe: results of a randomized quality of life focused clinical trial. Int J Cancer (2005) 1.17
Point-of-care assessment of microvascular blood flow in critically ill patients. Intensive Care Med (2009) 1.16
Fluid resuscitation influences cardiovascular performance and mortality in a murine model of sepsis. Intensive Care Med (2008) 1.14
Septic shock--vasopressin, norepinephrine, and urgency. N Engl J Med (2008) 1.12
Early predictors of longterm outcome in patients with juvenile rheumatoid arthritis: subset-specific correlations. J Rheumatol (2003) 1.10
Cloning and characterization of the human heparanase-1 (HPR1) gene promoter: role of GA-binding protein and Sp1 in regulating HPR1 basal promoter activity. J Biol Chem (2002) 1.09
Etiology and determinants of sexually transmitted infections in Karnataka state, south India. Sex Transm Dis (2010) 1.09
The pathophysiology of septic shock. Crit Care Clin (2009) 1.08
Cardiovascular response to dobutamine stress predicts outcome in severe sepsis and septic shock. Crit Care (2008) 1.07
Cardiogenic shock. Crit Care Med (2008) 1.06
Timing of vasopressor initiation and mortality in septic shock: a cohort study. Crit Care (2014) 1.05
Multiple organ dysfunction after return of spontaneous circulation in postcardiac arrest syndrome. Crit Care Med (2013) 1.05
Immunogenetic risks of anti-cyclical citrullinated peptide antibodies in a North American Native population with rheumatoid arthritis and their first-degree relatives. J Rheumatol (2009) 1.01
Human serum from patients with septic shock activates transcription factors STAT1, IRF1, and NF-kappaB and induces apoptosis in human cardiac myocytes. J Biol Chem (2005) 1.00
Impact of diabetes on maternal-fetal outcomes in Manitoba: Relationship with ethnic and environmental factors. Clin Invest Med (2008) 0.98
Risk factors for acquisition of endemic blastomycosis. Can J Infect Dis Med Microbiol (2009) 0.98
Adenosine deaminase inhibition attenuates microvascular dysfunction and improves survival in sepsis. Am J Respir Crit Care Med (2002) 0.97
Moving some articles to electronic (online) only publication. Crit Care Med (2013) 0.96
Defining the predictors of the placebo response in irritable bowel syndrome. Clin Gastroenterol Hepatol (2005) 0.96
Discordance between microvascular permeability and leukocyte dynamics in septic inducible nitric oxide synthase deficient mice. Crit Care (2007) 0.96
Sepsis and septic shock: a history. Crit Care Clin (2009) 0.96
Early arterial hypotension is common in the post-cardiac arrest syndrome and associated with increased in-hospital mortality. Resuscitation (2008) 0.96
Risk factors for infectious spondylodiscitis in patients receiving hemodialysis. Infect Control Hosp Epidemiol (2008) 0.96
Clinical characteristics and outcomes in patients with pulmonary blastomycosis. Mycopathologia (2008) 0.95
Interleukin-10 blunts the human inflammatory response to lipopolysaccharide without affecting the cardiovascular response. Crit Care Med (2005) 0.95
Mycobacterium tuberculosis septic shock. Chest (2013) 0.95
Characterizing the HIV epidemic in the prairie provinces. Can J Infect Dis Med Microbiol (2012) 0.93
Cardiac disease in myasthenia gravis: a literature review. J Clin Neuromuscul Dis (2003) 0.93
Statin underuse and low prevalence of LDL-C control among U.S. adults at high risk of coronary heart disease. Am J Med Sci (2014) 0.93
Predictors of early inactive disease in a juvenile idiopathic arthritis cohort: results of a Canadian multicenter, prospective inception cohort study. Arthritis Rheum (2009) 0.92
Preload-independent mechanisms contribute to increased stroke volume following large volume saline infusion in normal volunteers: a prospective interventional study. Crit Care (2004) 0.92
Antimicrobial therapeutic determinants of outcomes from septic shock among patients with cirrhosis. Hepatology (2012) 0.91
Flow cytometric quantification of bacteria in vaginal swab samples self-collected by adolescents attending a gynecology clinic. J Microbiol Methods (2008) 0.91
Ventricular dilation is associated with improved cardiovascular performance and survival in sepsis. Chest (2010) 0.91
Role of myeloid cell factor-1 (Mcl-1) in chronic lymphocytic leukemia. Leuk Lymphoma (2004) 0.90
Severe sepsis and therapy with activated protein C. N Engl J Med (2005) 0.90
Evaluation of education in palliative care: determining the effects on nurses' knowledge and attitudes. J Palliat Care (2005) 0.89
Predictors of pain in children with established juvenile rheumatoid arthritis. Arthritis Rheum (2004) 0.89
Is obesity associated with an increased risk for airway hyperresponsiveness and development of asthma? Allergy Asthma Clin Immunol (2008) 0.88
Radiologic outcome and its relationship to functional disability in juvenile rheumatoid arthritis. J Rheumatol (2003) 0.87
Experimental human endotoxemia is associated with depression of load-independent contractility indices: prevention by the lipid a analogue E5531. Chest (2004) 0.87