Published in N Engl J Med on April 01, 2004
Linking inpatient clinical registry data to Medicare claims data using indirect identifiers. Am Heart J (2009) 3.57
Registry research and medical privacy. N Engl J Med (2004) 3.49
National survey of British public's views on use of identifiable medical data by the National Cancer Registry. BMJ (2006) 2.92
Evaluating common de-identification heuristics for personal health information. J Med Internet Res (2006) 2.69
Harmonizing international trials of early goal-directed resuscitation for severe sepsis and septic shock: methodology of ProCESS, ARISE, and ProMISe. Intensive Care Med (2013) 2.44
The Vermont Diabetes Information System (VDIS): study design and subject recruitment for a cluster randomized trial of a decision support system in a regional sample of primary care practices. Clin Trials (2004) 2.05
Alternatives to project-specific consent for access to personal information for health research: what is the opinion of the Canadian public? J Am Med Inform Assoc (2007) 1.98
Prospective study of clinician-entered research data in the Emergency Department using an Internet-based system after the HIPAA Privacy Rule. BMC Med Inform Decis Mak (2004) 1.95
Bias from requiring explicit consent from all participants in observational research: prospective, population based study. BMJ (2005) 1.88
Electronic data collection options for practice-based research networks. Ann Fam Med (2005) 1.84
Deferred consent in emergency intensive care research: what if the patient dies early? Use the data or not? Intensive Care Med (2007) 1.76
Evaluating predictors of geographic area population size cut-offs to manage re-identification risk. J Am Med Inform Assoc (2008) 1.67
Selection bias resulting from the requirement for prior consent in observational research: a community cohort of people with ischaemic heart disease. Heart (2007) 1.66
Record linkage research and informed consent: who consents? BMC Health Serv Res (2007) 1.65
Sharing patient data: competing demands of privacy, trust and research in primary care. Br J Gen Pract (2005) 1.48
Coordination and management of multicenter clinical studies in trauma: Experience from the PRospective Observational Multicenter Major Trauma Transfusion (PROMMTT) Study. Resuscitation (2011) 1.46
Practice-based research network studies in the age of HIPAA. Ann Fam Med (2005) 1.36
Impact of privacy legislation on the number and characteristics of people who are recruited for research: a randomised controlled trial. J Med Ethics (2006) 1.23
The effect of privacy legislation on observational research. CMAJ (2008) 1.22
Registries and informed consent. N Engl J Med (2004) 1.18
Ethical issues in implementation research: a discussion of the problems in achieving informed consent. Implement Sci (2008) 1.12
Evaluating the generalizability of a large streamlined cardiovascular trial: comparing hospitals and patients in the dual antiplatelet therapy study versus the National Cardiovascular Data Registry. Circ Cardiovasc Qual Outcomes (2014) 1.11
Survey of informed consent for registration of congenital anomalies in Europe. BMJ (2005) 1.09
Determinants of variations in coronary revascularization practices. CMAJ (2011) 1.08
Passive consent for clinical research in the age of HIPAA. J Gen Intern Med (2006) 1.07
Neighborhood income and individual education: effect on survival after myocardial infarction. Mayo Clin Proc (2008) 1.01
Understanding the global epidemiology of pediatric critical illness: the power, pitfalls, and practicalities of point prevalence studies. Pediatr Crit Care Med (2014) 1.00
Variation in recruitment across sites in a consent-based clinical data registry: lessons from the Canadian Stroke Network. BMC Med Ethics (2006) 0.97
Institutional variability in a minimal risk, population-based study: recognizing policy barriers to health services research. Health Serv Res (2005) 0.95
Long-term trajectory of leisure time physical activity and survival after first myocardial infarction: a population-based cohort study. Eur J Epidemiol (2010) 0.92
Ethical justification for conducting public health surveillance without patient consent. Am J Public Health (2011) 0.91
Assessing the impact of the requirement for explicit consent in a hospital-based stroke study. QJM (2008) 0.88
Analysis of informed consent document utilization in a minimal-risk genetic study. Ann Intern Med (2011) 0.87
The importance of purpose: moving beyond consent in the societal use of personal health information. Ann Intern Med (2014) 0.87
Reduced population burden of road transport-related major trauma after introduction of an inclusive trauma system. Ann Surg (2015) 0.87
Prognostic value of cardiac troponin T after myocardial infarction: a contemporary community experience. Mayo Clin Proc (2012) 0.86
Shifting paradigms in health services research ethics. Consent, privacy, and the challenges for IRBs. J Gen Intern Med (2006) 0.86
Differences in stroke outcome based on sex. Neurology (2010) 0.85
Early observational research and registries during the 2009-2010 influenza A pandemic. Crit Care Med (2010) 0.85
Estimating the information gap between emergency department records of community medication compared to on-line access to the community-based pharmacy records. J Am Med Inform Assoc (2013) 0.84
Real-world data in the United Kingdom: opportunities and challenges. BMC Med (2016) 0.83
Informed consent: the rate-limiting step in acute stroke trials. Front Neurol (2011) 0.83
The Lombardia Stroke Unit Registry: 1-year experience of a web-based hospital stroke registry. Neurol Sci (2010) 0.82
Variability in the Perception of Informed Consent for IV-tPA during Telestroke Consultation. Front Neurol (2012) 0.81
Public opinion of a stroke clinical trial using exception from informed consent. Int J Emerg Med (2010) 0.81
AOA Symposium. Barriers (threats) to clinical research. J Bone Joint Surg Am (2008) 0.80
Modelling long term disability following injury: comparison of three approaches for handling multiple injuries. PLoS One (2011) 0.79
Recruiting participants for injury studies in emergency departments. Inj Prev (2007) 0.79
'No Time to be Lost!' Ethical considerations on consent for inclusion in emergency pharmacological research in severe traumatic brain injury in the European Union. Sci Eng Ethics (2007) 0.78
Waiver of consent in noninterventional, observational emergency research: the PROMMTT experience. J Trauma Acute Care Surg (2013) 0.78
Changes in stroke research productivity: A global perspective. Surg Neurol Int (2012) 0.78
Anticoagulation after anterior myocardial infarction and the risk of stroke. PLoS One (2010) 0.78
Ethical and practical challenges to studying patients who opt out of large-scale biorepository research. J Am Med Inform Assoc (2013) 0.77
Better outcomes for hospitalized patients with TIA when in stroke units: An observational study. Neurology (2016) 0.77
A renal registry for Africa: first steps. Clin Kidney J (2015) 0.77
Can current electronic systems meet drug safety and effectiveness requirements? AMIA Annu Symp Proc (2005) 0.77
Meeting the privacy requirements for the development of a multi-centre patient registry in Canada: the Rick Hansen Spinal Cord Injury Registry. Healthc Policy (2013) 0.76
Use of calcium channel blockers after stroke is not associated with poor outcome: a cohort from the registry of the Canadian stroke network. J Neurol (2006) 0.76
A survey of patient perspectives on the research use of health information and biospecimens. BMC Med Ethics (2016) 0.76
Association between perception of fault for the crash and function, return to work and health status 1 year after road traffic injury: a registry-based cohort study. BMJ Open (2015) 0.76
A national strategy for waiting-times research? CMAJ (2005) 0.76
Recommendations in relation to the EU clinical trials directive and medical research involving incapacitated adults. Wien Klin Wochenschr (2006) 0.75
Concurrent physician-diagnosed asthma and chronic obstructive pulmonary disease: A population study of prevalence, incidence and mortality. PLoS One (2017) 0.75
Web-based tool for dynamic functional outcome after acute ischemic stroke and comparison with existing models. BMC Neurol (2014) 0.75
Data protection and the promotion of health research. Healthc Policy (2007) 0.75
Ethical issues in using data from quality management programs. Eur Spine J (2009) 0.75
Improving outcomes for hospital patients with critical bleeding requiring massive transfusion: the Australian and New Zealand Massive Transfusion Registry study methodology. BMC Res Notes (2016) 0.75
Data protection and the promotion of health research. Healthc Policy (2007) 0.75
Registries and informed consent. N Engl J Med (2004) 0.75
Effect of older age on treatment decisions and outcomes among patients with traumatic spinal cord injury. CMAJ (2015) 0.75
Statistician expert witnesses in agreement on relative hazards. Clin Risk (2012) 0.75
Parental opinions regarding an opt-out consent process for inpatient pediatric prospective observational research in the US. Pragmat Obs Res (2017) 0.75
Joint replacement recipients' views about health information privacy. Health Expect (2013) 0.75
A Randomised Controlled Trial of Consent Procedures for the Use of Residual Tissues for Medical Research: Preferences of and Implications for Patients, Research and Clinical Practice. PLoS One (2016) 0.75
Guidelines for confidentiality and cancer registration. Br J Cancer (2005) 0.75
Development and implementation of the Ontario Stroke System: the use of evidence. Int J Integr Care (2007) 0.75
Ambulatory surveillance of patients referred for cardiac rehabilitation following cardiac hospitalization: a feasibility study. Can J Cardiol (2012) 0.75
Predictable and SuStainable Implementation of National Cardiovascular Registries (PASSION) infrastructure: A think tank report from Medical Device Epidemiological Network Initiative (MDEpiNet). Am Heart J (2015) 0.75
Informed consent and registry-based research - the case of the Danish circumcision registry. BMC Med Ethics (2017) 0.75
Stenting versus endarterectomy for treatment of carotid-artery stenosis. N Engl J Med (2010) 17.57
Endovascular therapy after intravenous t-PA versus t-PA alone for stroke. N Engl J Med (2013) 14.78
Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med (2015) 12.70
Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study. N Engl J Med (2004) 11.44
Outcome of heart failure with preserved ejection fraction in a population-based study. N Engl J Med (2006) 10.58
SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials. BMJ (2013) 9.01
SPIRIT 2013 statement: defining standard protocol items for clinical trials. Ann Intern Med (2013) 8.21
Atrial fibrillation in patients with cryptogenic stroke. N Engl J Med (2014) 6.73
Relation between age and cardiovascular disease in men and women with diabetes compared with non-diabetic people: a population-based retrospective cohort study. Lancet (2006) 6.64
Post-Romanow pharmacare: last-dollar first...first-dollar lost? Healthc Pap (2004) 5.56
Bisphosphonate use and the risk of subtrochanteric or femoral shaft fractures in older women. JAMA (2011) 5.33
Risk of vertebrobasilar stroke and chiropractic care: results of a population-based case-control and case-crossover study. Spine (Phila Pa 1976) (2008) 4.97
Drug-drug interactions among elderly patients hospitalized for drug toxicity. JAMA (2003) 4.00
Association between the 2008-09 seasonal influenza vaccine and pandemic H1N1 illness during Spring-Summer 2009: four observational studies from Canada. PLoS Med (2010) 3.85
Propensity score methods gave similar results to traditional regression modeling in observational studies: a systematic review. J Clin Epidemiol (2005) 3.76
Prospective study evaluating the impact of tissue confirmation of metastatic disease in patients with breast cancer. J Clin Oncol (2011) 3.46
The PLAN score: a bedside prediction rule for death and severe disability following acute ischemic stroke. Arch Intern Med (2012) 3.26
Epidural anaesthesia and survival after intermediate-to-high risk non-cardiac surgery: a population-based cohort study. Lancet (2008) 3.22
Effect of discharge summary availability during post-discharge visits on hospital readmission. J Gen Intern Med (2002) 3.21
Potentially preventable strokes in high-risk patients with atrial fibrillation who are not adequately anticoagulated. Stroke (2008) 3.14
Risk-treatment mismatch in the pharmacotherapy of heart failure. JAMA (2005) 3.05
Clinical inertia in response to inadequate glycemic control: do specialists differ from primary care physicians? Diabetes Care (2005) 3.02
Oral anticoagulants vs aspirin in nonvalvular atrial fibrillation: an individual patient meta-analysis. JAMA (2002) 2.94
National trends in rates of death and hospital admissions related to acute myocardial infarction, heart failure and stroke, 1994-2004. CMAJ (2009) 2.89
Impact of adverse events on prescribing warfarin in patients with atrial fibrillation: matched pair analysis. BMJ (2006) 2.71
A systematic review of the Charlson comorbidity index using Canadian administrative databases: a perspective on risk adjustment in critical care research. J Crit Care (2005) 2.62
Revisiting Rose: strategies for reducing coronary heart disease. BMJ (2006) 2.53
Statin therapy and outcome after ischemic stroke: systematic review and meta-analysis of observational studies and randomized trials. Stroke (2013) 2.53
Projected incidence of mechanical ventilation in Ontario to 2026: Preparing for the aging baby boomers. Crit Care Med (2005) 2.52
Public engagement in setting priorities in health care. CMAJ (2008) 2.37
Safety and efficacy of NA-1 in patients with iatrogenic stroke after endovascular aneurysm repair (ENACT): a phase 2, randomised, double-blind, placebo-controlled trial. Lancet Neurol (2012) 2.34
Mechanical ventilation in Ontario, 1992-2000: incidence, survival, and hospital bed utilization of noncardiac surgery adult patients. Crit Care Med (2004) 2.34
Outcomes and processes of care related to preoperative medical consultation. Arch Intern Med (2010) 2.34
Proliferation of prenatal ultrasonography. CMAJ (2010) 2.33
IScore: a risk score to predict death early after hospitalization for an acute ischemic stroke. Circulation (2011) 2.29
Sex differences in carotid endarterectomy outcomes: results from the Ontario Carotid Endarterectomy Registry. Stroke (2003) 2.28
Written informed consent and selection bias in observational studies using medical records: systematic review. BMJ (2009) 2.27
Variation in the practice of preoperative medical consultation for major elective noncardiac surgery: a population-based study. Anesthesiology (2012) 2.26
Continuity of care and patient outcomes after hospital discharge. J Gen Intern Med (2004) 2.26
Preadmission antithrombotic treatment and stroke severity in patients with atrial fibrillation and acute ischaemic stroke: an observational study. Lancet Neurol (2006) 2.23
Effect of selective cyclooxygenase 2 inhibitors and naproxen on short-term risk of acute myocardial infarction in the elderly. Arch Intern Med (2003) 2.18
Effect of cardiac and noncardiac conditions on survival after defibrillator implantation. J Am Coll Cardiol (2007) 2.15
Age, risk-benefit trade-offs, and the projected effects of evidence-based therapies. Am J Med (2004) 2.08
Sex differences in stroke care and outcomes: results from the Registry of the Canadian Stroke Network. Stroke (2005) 2.08
The prognostic effect of cigarette smoking on stroke severity, disability, length of stay in hospital, and mortality in a cohort with cerebrovascular disease. J Stroke Cerebrovasc Dis (2013) 2.06
Longer wait times increase overall mortality in patients with bladder cancer. J Urol (2009) 2.05
Aspirin use and outcomes in a community-based cohort of 7352 patients discharged after first hospitalization for heart failure. Circulation (2006) 2.05
The value of positron emission tomography in the clinical evaluation of dementia. J Am Geriatr Soc (2003) 2.05
A clinical prediction rule to identify patients with atrial fibrillation and a low risk for stroke while taking aspirin. Arch Intern Med (2003) 2.04
Effectiveness and efficiency of different guidelines on statin treatment for preventing deaths from coronary heart disease: modelling study. BMJ (2006) 2.03
Association between weekend hospital presentation and stroke fatality. Neurology (2010) 2.00
The rise of people power. Nature (2011) 1.99
Escalating levels of access to in-hospital care and stroke mortality. Stroke (2008) 1.97
Cholinesterase inhibitors and hospitalization for bradycardia: a population-based study. PLoS Med (2009) 1.94
Bone density and structure in healthy postmenopausal women treated with exemestane for the primary prevention of breast cancer: a nested substudy of the MAP.3 randomised controlled trial. Lancet Oncol (2012) 1.94
Hemorrhage during warfarin therapy associated with cotrimoxazole and other urinary tract anti-infective agents: a population-based study. Arch Intern Med (2010) 1.87
Administrative data algorithms can describe ambulatory physician utilization. Health Serv Res (2007) 1.86
Anticoagulant-related bleeding in older persons with atrial fibrillation: physicians' fears often unfounded. Arch Intern Med (2003) 1.85
Views on health information sharing and privacy from primary care practices using electronic medical records. Int J Med Inform (2010) 1.83
Early deaths in patients with heart failure discharged from the emergency department: a population-based analysis. Circ Heart Fail (2010) 1.83
Risk factors for death or stroke after carotid endarterectomy: observations from the Ontario Carotid Endarterectomy Registry. Stroke (2003) 1.74
Does the public think it is reasonable to wait for more evidence before funding innovative health technologies? The case of PET scanning in Ontario. Int J Technol Assess Health Care (2010) 1.73
Preference-based antithrombotic therapy in atrial fibrillation: implications for clinical decision making. Med Decis Making (2005) 1.68
Reinitiation of anticoagulation after warfarin-associated intracranial hemorrhage and mortality risk: the Best Practice for Reinitiating Anticoagulation Therapy After Intracranial Bleeding (BRAIN) study. Can J Cardiol (2011) 1.66
Comparative operative outcomes of early and delayed cholecystectomy for acute cholecystitis: a population-based propensity score analysis. Ann Surg (2014) 1.65
Statins and intracerebral hemorrhage: a retrospective cohort study. Arch Neurol (2011) 1.63
Time to disease-modifying antirheumatic drug treatment in rheumatoid arthritis and its predictors: a national, multicenter, retrospective cohort. J Rheumatol (2012) 1.60
Patterns of care after magnetic resonance imaging of the spine in primary care. Spine (Phila Pa 1976) (2013) 1.59
TPA use for stroke in the Registry of the Canadian Stroke Network. Can J Neurol Sci (2005) 1.58
Recent trends in cardiovascular complications among men and women with and without diabetes. Diabetes Care (2006) 1.57
Risk of upper gastrointestinal hemorrhage in warfarin users treated with nonselective NSAIDs or COX-2 inhibitors. Arch Intern Med (2005) 1.56
Neighborhood income and stroke care and outcomes. Neurology (2012) 1.56
Non-invasive cardiac stress testing before elective major non-cardiac surgery: population based cohort study. BMJ (2010) 1.55
Carotid artery stenting: meeting the recruitment challenge of a clinical trial. Stroke (2005) 1.55
Higher surgeon and hospital volume improves long-term survival after radical cystectomy. Cancer (2013) 1.52
Variables associated with 7-day, 30-day, and 1-year fatality after ischemic stroke. Stroke (2008) 1.51
Antihypertensive therapy and incidence of type 2 diabetes in an elderly cohort. Diabetes Care (2004) 1.50
The 2003 Canadian recommendations for dyslipidemia management: revisions are needed. CMAJ (2005) 1.49
A qualitative study of physicians' perceptions of three decision aids. Patient Educ Couns (2003) 1.49
Effect of depression on five-year mortality after an acute coronary syndrome. Am J Cardiol (2005) 1.48
Dissemination of discharge summaries. Not reaching follow-up physicians. Can Fam Physician (2002) 1.46
Short-term outcomes after symptomatic internal carotid artery occlusion. Stroke (2011) 1.43
Early management of newly diagnosed rheumatoid arthritis by Canadian rheumatologists: a national, multicenter, retrospective cohort. J Rheumatol (2011) 1.43