PubRank

Nahum Sonenberg

Author PubWeight™ 434.43‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 2008 32.08
2 Upstream and downstream of mTOR. Genes Dev 2004 21.61
3 Regulation of mRNA translation and stability by microRNAs. Annu Rev Biochem 2010 12.06
4 Translational control in stress and apoptosis. Nat Rev Mol Cell Biol 2005 8.91
5 Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells. Cancer Res 2006 6.99
6 XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity 2004 6.72
7 Regulation of cap-dependent translation by eIF4E inhibitory proteins. Nature 2005 6.69
8 Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells. Cancer Res 2007 5.45
9 mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs. Science 2010 4.81
10 Translational control of long-lasting synaptic plasticity and memory. Neuron 2009 4.77
11 Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation. Mol Cell 2009 4.57
12 RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation. J Biol Chem 2007 4.45
13 MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F. Science 2007 4.33
14 A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus. Proc Natl Acad Sci U S A 2001 4.16
15 Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha. Mol Cell Biol 2002 4.11
16 Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis. Cell 2010 4.01
17 Mammalian poly(A)-binding protein is a eukaryotic translation initiation factor, which acts via multiple mechanisms. Genes Dev 2005 3.92
18 The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation. Mol Cell Biol 2003 3.90
19 eIF4E--from translation to transformation. Oncogene 2004 3.78
20 Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2. Nature 2010 3.77
21 Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity. J Biol Chem 2005 3.74
22 The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity. EMBO J 2006 3.57
23 eIF2alpha phosphorylation bidirectionally regulates the switch from short- to long-term synaptic plasticity and memory. Cell 2007 3.46
24 The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC. Nat Struct Mol Biol 2012 3.42
25 Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases. EMBO J 2004 3.29
26 Autism-related deficits via dysregulated eIF4E-dependent translational control. Nature 2012 3.13
27 eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression. Proc Natl Acad Sci U S A 2010 3.13
28 The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP. Cell 2008 3.10
29 Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2. Mol Cell Biol 2004 3.00
30 14-3-3sigma controls mitotic translation to facilitate cytokinesis. Nature 2007 2.98
31 Activation of translation complex eIF4F is essential for the genesis and maintenance of the malignant phenotype in human mammary epithelial cells. Cancer Cell 2004 2.91
32 Dissecting the role of mTOR: lessons from mTOR inhibitors. Biochim Biophys Acta 2009 2.89
33 Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2. J Clin Invest 2007 2.86
34 A new paradigm for translational control: inhibition via 5'-3' mRNA tethering by Bicoid and the eIF4E cognate 4EHP. Cell 2005 2.80
35 Atrophy of S6K1(-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control. Nat Cell Biol 2005 2.80
36 Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2. Nature 2005 2.67
37 miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT. Nat Struct Mol Biol 2011 2.61
38 Topology and regulation of the human eIF4A/4G/4H helicase complex in translation initiation. Cell 2009 2.60
39 Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins. J Mol Biol 2002 2.53
40 A role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decay. J Cell Biol 2005 2.51
41 A novel role of the mammalian GSPT/eRF3 associating with poly(A)-binding protein in Cap/Poly(A)-dependent translation. J Biol Chem 2002 2.43
42 mRNA helicases: the tacticians of translational control. Nat Rev Mol Cell Biol 2011 2.41
43 Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control. EMBO J 2006 2.41
44 A novel function of the MA-3 domains in transformation and translation suppressor Pdcd4 is essential for its binding to eukaryotic translation initiation factor 4A. Mol Cell Biol 2004 2.38
45 eIF4AIII binds spliced mRNA in the exon junction complex and is essential for nonsense-mediated decay. Nat Struct Mol Biol 2004 2.38
46 Epigenetic activation of a subset of mRNAs by eIF4E explains its effects on cell proliferation. PLoS One 2007 2.35
47 The translation repressor 4E-BP2 is critical for eIF4F complex formation, synaptic plasticity, and memory in the hippocampus. J Neurosci 2005 2.33
48 Translational control of the innate immune response through IRF-7. Nature 2008 2.30
49 Tumstatin, an endothelial cell-specific inhibitor of protein synthesis. Science 2002 2.28
50 Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53. EMBO J 2007 2.27
51 The dynamics of mammalian P body transport, assembly, and disassembly in vivo. Mol Biol Cell 2008 2.25
52 The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-activated protein kinase. Cancer Prev Res (Phila) 2008 2.23
53 Translational homeostasis via the mRNA cap-binding protein, eIF4E. Mol Cell 2012 2.19
54 The Akt of translational control. Oncogene 2005 2.15
55 Cap and cap-binding proteins in the control of gene expression. Wiley Interdiscip Rev RNA 2010 2.11
56 Reconstitution reveals the functional core of mammalian eIF3. EMBO J 2007 2.06
57 Regulation of eukaryotic initiation factor 4E by converging signaling pathways during metabotropic glutamate receptor-dependent long-term depression. J Neurosci 2006 2.04
58 MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. J Clin Invest 2010 2.04
59 Activation of GCN2 in UV-irradiated cells inhibits translation. Curr Biol 2002 2.02
60 Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection. Cell Host Microbe 2011 2.01
61 Translation initiator EIF4G1 mutations in familial Parkinson disease. Am J Hum Genet 2011 2.00
62 Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation. Proc Natl Acad Sci U S A 2005 2.00
63 Two structurally atypical HEAT domains in the C-terminal portion of human eIF4G support binding to eIF4A and Mnk1. Structure 2006 1.99
64 Eukaryotic translation initiation factor 4E availability controls the switch between cap-dependent and internal ribosomal entry site-mediated translation. Mol Cell Biol 2005 1.99
65 A nuclear translation-like factor eIF4AIII is recruited to the mRNA during splicing and functions in nonsense-mediated decay. Proc Natl Acad Sci U S A 2004 1.97
66 A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity. Mol Cell Proteomics 2005 1.95
67 Akt-mediated YB-1 phosphorylation activates translation of silent mRNA species. Mol Cell Biol 2006 1.93
68 Phosphorylation of eukaryotic translation initiation factor 4E is critical for growth. Mol Cell Biol 2002 1.92
69 mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation. Cell Metab 2013 1.91
70 La autoantigen is necessary for optimal function of the poliovirus and hepatitis C virus internal ribosome entry site in vivo and in vitro. Mol Cell Biol 2004 1.87
71 Pharmacological brake-release of mRNA translation enhances cognitive memory. Elife 2013 1.85
72 Starvation and oxidative stress resistance in Drosophila are mediated through the eIF4E-binding protein, d4E-BP. Genes Dev 2005 1.84
73 Antiviral effect of the mammalian translation initiation factor 2alpha kinase GCN2 against RNA viruses. EMBO J 2006 1.79
74 S6K1 plays a critical role in early adipocyte differentiation. Dev Cell 2010 1.74
75 The leader of human immunodeficiency virus type 1 genomic RNA harbors an internal ribosome entry segment that is active during the G2/M phase of the cell cycle. J Virol 2003 1.71
76 Signaling control of mRNA translation in cancer pathogenesis. Oncogene 2004 1.71
77 Control of eIF4E cellular localization by eIF4E-binding proteins, 4E-BPs. RNA 2008 1.69
78 Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation. Nat Struct Mol Biol 2010 1.66
79 Dendritic BC1 RNA: functional role in regulation of translation initiation. J Neurosci 2002 1.64
80 Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2. EMBO J 2006 1.64
81 ATF4-mediated induction of 4E-BP1 contributes to pancreatic beta cell survival under endoplasmic reticulum stress. Cell Metab 2008 1.62
82 eIF4E/4E-BP ratio predicts the efficacy of mTOR targeted therapies. Cancer Res 2012 1.62
83 HuR protein attenuates miRNA-mediated repression by promoting miRISC dissociation from the target RNA. Nucleic Acids Res 2012 1.58
84 Pervasive and cooperative deadenylation of 3'UTRs by embryonic microRNA families. Mol Cell 2010 1.55
85 Paip1 interacts with poly(A) binding protein through two independent binding motifs. Mol Cell Biol 2002 1.55
86 miRNA-132 orchestrates chromatin remodeling and translational control of the circadian clock. Hum Mol Genet 2010 1.53
87 UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant. Genes Dev 2004 1.52
88 Structural basis of ligand recognition by PABC, a highly specific peptide-binding domain found in poly(A)-binding protein and a HECT ubiquitin ligase. EMBO J 2003 1.52
89 Novel translational control in Arc-dependent long term potentiation consolidation in vivo. J Biol Chem 2009 1.52
90 p53-dependent translational control of senescence and transformation via 4E-BPs. Cancer Cell 2009 1.51
91 Principles of translational control: an overview. Cold Spring Harb Perspect Biol 2012 1.51
92 Problems with co-funding in Canada. Science 2005 1.48
93 Cap-dependent translational inhibition establishes two opposing morphogen gradients in Drosophila embryos. Curr Biol 2006 1.47
94 Hepatitis C therapeutics: current status and emerging strategies. Nat Rev Drug Discov 2002 1.46
95 Structural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolin. Nat Struct Mol Biol 2013 1.45
96 A mechanism of translational repression by competition of Paip2 with eIF4G for poly(A) binding protein (PABP) binding. Proc Natl Acad Sci U S A 2006 1.44
97 Host translation at the nexus of infection and immunity. Cell Host Microbe 2012 1.43
98 An efficient system for cap- and poly(A)-dependent translation in vitro. Methods Mol Biol 2004 1.43
99 Distinct perturbation of the translatome by the antidiabetic drug metformin. Proc Natl Acad Sci U S A 2012 1.43
100 Translational control of cell fate: availability of phosphorylation sites on translational repressor 4E-BP1 governs its proapoptotic potency. Mol Cell Biol 2002 1.42
101 Regulatory effects of mammalian target of rapamycin-activated pathways in type I and II interferon signaling. J Biol Chem 2006 1.41
102 Signaling from Akt to FRAP/TOR targets both 4E-BP and S6K in Drosophila melanogaster. Mol Cell Biol 2003 1.41
103 Control of cell survival and proliferation by mammalian eukaryotic initiation factor 4B. Mol Cell Biol 2010 1.41
104 Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type I IFN production. Proc Natl Acad Sci U S A 2010 1.39
105 Postnatal deamidation of 4E-BP2 in brain enhances its association with raptor and alters kinetics of excitatory synaptic transmission. Mol Cell 2010 1.38
106 Activation of the p70 S6 kinase and phosphorylation of the 4E-BP1 repressor of mRNA translation by type I interferons. J Biol Chem 2003 1.36
107 Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases. Cancer Res 2011 1.35
108 The helicase protein DHX29 promotes translation initiation, cell proliferation, and tumorigenesis. Proc Natl Acad Sci U S A 2009 1.34
109 Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain. Mol Pain 2011 1.32
110 Gene fusion and overlapping reading frames in the mammalian genes for 4E-BP3 and MASK. J Biol Chem 2003 1.31
111 Poly(A)-binding protein-interacting protein 1 binds to eukaryotic translation initiation factor 3 to stimulate translation. Mol Cell Biol 2008 1.30
112 The protein kinase PKR: a molecular clock that sequentially activates survival and death programs. EMBO J 2004 1.29
113 Requirement of RNA binding of mammalian eukaryotic translation initiation factor 4GI (eIF4GI) for efficient interaction of eIF4E with the mRNA cap. Mol Cell Biol 2008 1.27
114 Mechanisms governing the control of mRNA translation. Phys Biol 2010 1.27
115 ERK and mTOR signaling couple beta-adrenergic receptors to translation initiation machinery to gate induction of protein synthesis-dependent long-term potentiation. J Biol Chem 2007 1.27
116 The ELAV protein HuD stimulates cap-dependent translation in a Poly(A)- and eIF4A-dependent manner. Mol Cell 2009 1.27
117 Phosphorylation of eIF4E attenuates its interaction with mRNA 5' cap analogs by electrostatic repulsion: intein-mediated protein ligation strategy to obtain phosphorylated protein. RNA 2003 1.27
118 An efficient mammalian cell-free translation system supplemented with translation factors. Protein Expr Purif 2005 1.25
119 RNA aptamers to initiation factor 4A helicase hinder cap-dependent translation by blocking ATP hydrolysis. RNA 2003 1.23
120 Arabidopsis Argonaute MID domains use their nucleotide specificity loop to sort small RNAs. EMBO J 2012 1.21
121 Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling. J Biol Chem 2012 1.20
122 Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. J Med Chem 2009 1.19
123 Dual regulation of translation initiation and peptide chain elongation during BDNF-induced LTP in vivo: evidence for compartment-specific translation control. J Neurochem 2006 1.18
124 Cleavage of eukaryotic translation initiation factor 4GII within foot-and-mouth disease virus-infected cells: identification of the L-protease cleavage site in vitro. J Virol 2004 1.15
125 Resistance to vesicular stomatitis virus infection requires a functional cross talk between the eukaryotic translation initiation factor 2alpha kinases PERK and PKR. J Virol 2004 1.15
126 Influenza virus mRNA translation revisited: is the eIF4E cap-binding factor required for viral mRNA translation? J Virol 2007 1.15
127 Behavioral alterations in mice lacking the translation repressor 4E-BP2. Neurobiol Learn Mem 2006 1.15
128 Phenethyl isothiocyanate, a cancer chemopreventive constituent of cruciferous vegetables, inhibits cap-dependent translation by regulating the level and phosphorylation of 4E-BP1. Cancer Res 2007 1.14
129 Unique translation initiation of mRNAs-containing TISU element. Nucleic Acids Res 2011 1.12
130 Shared protein components of SINE RNPs. J Mol Biol 2002 1.09
131 A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development. Mol Cell Biol 2012 1.09
132 A translational rheostat for RFLAT-1 regulates RANTES expression in T lymphocytes. J Clin Invest 2002 1.08
133 eIF4B controls survival and proliferation and is regulated by proto-oncogenic signaling pathways. Cell Cycle 2010 1.07
134 Cell-free synthesis of encephalomyocarditis virus. J Virol 2003 1.07
135 General RNA-binding proteins have a function in poly(A)-binding protein-dependent translation. EMBO J 2008 1.06
136 mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK. Pain 2013 1.06
137 When translation meets metabolism: multiple links to diabetes. Endocr Rev 2003 1.06
138 Identification of differential translation in genome wide studies. Proc Natl Acad Sci U S A 2010 1.05
139 Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing. Nucleic Acids Res 2010 1.03
140 The mTOR pathway in hepatic malignancies. Hepatology 2013 1.02
141 Translational control mechanisms in long-lasting synaptic plasticity and memory. J Biol Chem 2010 1.02
142 Interaction of the eukaryotic initiation factor 4E with 4E-BP2 at a dynamic bipartite interface. Structure 2013 1.02
143 anota: Analysis of differential translation in genome-wide studies. Bioinformatics 2011 1.02
144 Positive heat capacity change upon specific binding of translation initiation factor eIF4E to mRNA 5' cap. Biochemistry 2002 1.02
145 Current status and challenges associated with targeting mTOR for cancer therapy. BioDrugs 2009 1.02
146 Fibronectin controls cap-dependent translation through beta1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathways. Proc Natl Acad Sci U S A 2005 1.01
147 Understanding how miRNAs post-transcriptionally regulate gene expression. Prog Mol Subcell Biol 2010 1.01
148 The Drosophila poly(A) binding protein-interacting protein, dPaip2, is a novel effector of cell growth. Mol Cell Biol 2004 1.01
149 The poly(A)-binding protein partner Paip2a controls translation during late spermiogenesis in mice. J Clin Invest 2010 1.01
150 Control of Paip1-eukayrotic translation initiation factor 3 interaction by amino acids through S6 kinase. Mol Cell Biol 2014 0.99
151 Weak binding affinity of human 4EHP for mRNA cap analogs. RNA 2007 0.98
152 High affinity RNA for mammalian initiation factor 4E interferes with mRNA-cap binding and inhibits translation. RNA 2005 0.98
153 Molecular and genetic crosstalks between mTOR and ERRα are key determinants of rapamycin-induced nonalcoholic fatty liver. Cell Metab 2013 0.98
154 Selective modification of eukaryotic initiation factor 4F (eIF4F) at the onset of cell differentiation: recruitment of eIF4GII and long-lasting phosphorylation of eIF4E. Mol Cell Biol 2004 0.98
155 Translational control of entrainment and synchrony of the suprachiasmatic circadian clock by mTOR/4E-BP1 signaling. Neuron 2013 0.97
156 Regulation of poly(A) binding protein function in translation: Characterization of the Paip2 homolog, Paip2B. RNA 2006 0.96
157 Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk. J Biol Chem 2004 0.96
158 RNA aptamers to mammalian initiation factor 4G inhibit cap-dependent translation by blocking the formation of initiation factor complexes. RNA 2006 0.96
159 Human rhinovirus 2A proteinase cleavage sites in eukaryotic initiation factors (eIF) 4GI and eIF4GII are different. J Virol 2003 0.96
160 Seasonal and state-dependent changes of eIF4E and 4E-BP1 during mammalian hibernation: implications for the control of translation during torpor. Am J Physiol Regul Integr Comp Physiol 2004 0.96
161 TOR is required for the retrograde regulation of synaptic homeostasis at the Drosophila neuromuscular junction. Neuron 2012 0.94
162 Translational control of gene expression: a molecular switch for memory storage. Prog Brain Res 2008 0.94
163 mTOR inhibitor efficacy is determined by the eIF4E/4E-BP ratio. Oncotarget 2012 0.93
164 Blocking the eIF2α kinase (PKR) enhances positive and negative forms of cortex-dependent taste memory. J Neurosci 2013 0.93
165 Translational control by the eukaryotic ribosome. Cell 2011 0.93
166 Vesicular stomatitis virus oncolysis of T lymphocytes requires cell cycle entry and translation initiation. J Virol 2008 0.93
167 Ablation of 4E-BP1/2 prevents hyperglycemia-mediated induction of VEGF expression in the rodent retina and in Muller cells in culture. Diabetes 2010 0.93
168 RAPping production of type I interferon in pDCs through mTOR. Nat Immunol 2008 0.93
169 The eukaryotic initiation factor eIF4H facilitates loop-binding, repetitive RNA unwinding by the eIF4A DEAD-box helicase. Nucleic Acids Res 2012 0.92
170 Toward a genome-wide landscape of translational control. Cold Spring Harb Perspect Biol 2013 0.92
171 Phosphorylation screening identifies translational initiation factor 4GII as an intracellular target of Ca(2+)/calmodulin-dependent protein kinase I. J Biol Chem 2003 0.92
172 Eukaryotic initiation factor 4E-3 is essential for meiotic chromosome segregation, cytokinesis and male fertility in Drosophila. Development 2012 0.92
173 IL-15 can signal via IL-15Rα, JNK, and NF-κB to drive RANTES production by myeloid cells. J Immunol 2012 0.92
174 Selective regulation of GluA subunit synthesis and AMPA receptor-mediated synaptic function and plasticity by the translation repressor 4E-BP2 in hippocampal pyramidal cells. J Neurosci 2013 0.91
175 Control of translation and miRNA-dependent repression by a novel poly(A) binding protein, hnRNP-Q. PLoS Biol 2013 0.91
176 Persistent transcription- and translation-dependent long-term potentiation induced by mGluR1 in hippocampal interneurons. J Neurosci 2009 0.91
177 Inactivation of the mTORC1-eukaryotic translation initiation factor 4E pathway alters stress granule formation. Mol Cell Biol 2013 0.91
178 Degradation of newly synthesized polypeptides by ribosome-associated RACK1/c-Jun N-terminal kinase/eukaryotic elongation factor 1A2 complex. Mol Cell Biol 2013 0.90
179 Translational regulatory mechanisms in synaptic plasticity and memory storage. Prog Mol Biol Transl Sci 2009 0.90
180 Poly(A)-binding protein binds to A-rich sequences via RNA-binding domains 1+2 and 3+4. RNA Biol 2006 0.89
181 An efficient system for let-7 microRNA and GW182 protein-mediated deadenylation in vitro. Methods Mol Biol 2011 0.89
182 Rheb (Ras homologue enriched in brain)-dependent mammalian target of rapamycin complex 1 (mTORC1) activation becomes indispensable for cardiac hypertrophic growth after early postnatal period. J Biol Chem 2013 0.89
183 Differential inhibition of protein translation machinery by curcumin in normal, immortalized, and malignant oral epithelial cells. Cancer Prev Res (Phila) 2010 0.88
184 Cap-dependent translation and control of the cell cycle. Prog Cell Cycle Res 2003 0.88
185 Ischemia-induced calpain activation causes eukaryotic (translation) initiation factor 4G1 (eIF4GI) degradation, protein synthesis inhibition, and neuronal death. Proc Natl Acad Sci U S A 2011 0.88
186 Role of 3'UTRs in the translation of mRNAs regulated by oncogenic eIF4E--a computational inference. PLoS One 2009 0.88
187 Control of synaptic plasticity and memory via suppression of poly(A)-binding protein. Neuron 2013 0.88
188 Modulation of 4E-BP1 function as a critical determinant of enzastaurin-induced apoptosis. Mol Cancer Ther 2010 0.87
189 Evidence for a tumor promoting effect of high-fat diet independent of insulin resistance in HER2/Neu mammary carcinogenesis. Breast Cancer Res Treat 2009 0.87
190 Nanopore detachment kinetics of poly(A) binding proteins from RNA molecules reveals the critical role of C-terminus interactions. Biophys J 2012 0.86
191 Granzyme B inhibits vaccinia virus production through proteolytic cleavage of eukaryotic initiation factor 4 gamma 3. PLoS Pathog 2011 0.86
192 Stimulation of picornavirus replication by the poly(A) tail in a cell-free extract is largely independent of the poly(A) binding protein (PABP). RNA 2007 0.86
193 Coordinated transcriptional and translational control in metabolic homeostasis in flies. Genes Dev 2007 0.86
194 eIF4E/4E-BP dissociation and 4E-BP degradation in the first mitotic division of the sea urchin embryo. Dev Biol 2003 0.85
195 Structural analysis of 5'-mRNA-cap interactions with the human AGO2 MID domain. EMBO Rep 2011 0.85
196 Regulation of protein synthesis by IGF-I in proximal tubular epithelial cells. Am J Physiol Renal Physiol 2002 0.85
197 Cell biology. Burn out or fade away? Science 2010 0.85
198 Association between LRRK2 and 4E-BP1 protein levels in normal and malignant cells. Oncol Rep 2011 0.85
199 Embryonic-stage-dependent changes in the level of eIF4E-binding proteins during early development of sea urchin embryos. J Cell Sci 2005 0.85
200 Akt-dependent Skp2 mRNA translation is required for exiting contact inhibition, oncogenesis, and adipogenesis. EMBO J 2012 0.84
201 [Translational control by the poly(A) binding protein: a check for mRNA integrity]. Mol Biol (Mosk) 2006 0.84
202 Distinct translational control in CD4+ T cell subsets. PLoS Genet 2013 0.84
203 Inhibitory properties of nucleic acid-binding ligands on protein synthesis. FEBS Lett 2005 0.83
204 Translational control of long-term synaptic plasticity and memory storage by eIF2alpha. Crit Rev Neurobiol 2006 0.82
205 Complete translation of the hepatitis C virus genome in vitro: membranes play a critical role in the maturation of all virus proteins except for NS3. J Virol 2005 0.82
206 Structural analysis of the DAP5 MIF4G domain and its interaction with eIF4A. Structure 2013 0.82
207 A highly efficient and robust in vitro translation system for expression of picornavirus and hepatitis C virus RNA genomes. Methods Enzymol 2007 0.81
208 A collection of caged compounds for probing roles of local translation in neurobiology. Bioorg Med Chem 2010 0.81
209 The Distribution of eIF4E-Family Members across Insecta. Comp Funct Genomics 2012 0.81
210 Impaired myelopoiesis in mice lacking the repressors of translation initiation, 4E-BP1 and 4E-BP2. Immunology 2008 0.81
211 Regulation of neuronal mRNA translation by CaM-kinase I phosphorylation of eIF4GII. J Neurosci 2012 0.81
212 A chemical genetic screen for mTOR pathway inhibitors based on 4E-BP-dependent nuclear accumulation of eIF4E. Chem Biol 2009 0.80
213 Repair of isoaspartate formation modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain. J Biol Chem 2010 0.80
214 Antiviral effects of interferon-β are enhanced in the absence of the translational suppressor 4E-BP1 in myocarditis induced by Coxsackievirus B3. Antivir Ther 2011 0.80
215 Mextli is a novel eukaryotic translation initiation factor 4E-binding protein that promotes translation in Drosophila melanogaster. Mol Cell Biol 2013 0.79
216 Functional and direct interaction between the RNA binding protein HuD and active Akt1. Nucleic Acids Res 2011 0.78
217 Crystallization and preliminary X-ray diffraction analysis of the MIF4G domain of DAP5. Acta Crystallogr Sect F Struct Biol Cryst Commun 2009 0.78
218 PABP interacting protein 2A (PAIP2A) regulates specific key proteins during spermiogenesis in the mouse. Biol Reprod 2012 0.78
219 Insulin stimulates IGFBP-2 expression in 3T3-L1 adipocytes through the PI3K/mTOR pathway. Mol Cell Endocrinol 2012 0.78
220 Crystallization and preliminary X-ray diffraction analysis of the middle domain of Paip1. Acta Crystallogr Sect F Struct Biol Cryst Commun 2009 0.75
221 Gimme phospho-serine five! Capping enzyme guanylyltransferase recognition of the RNA polymerase II CTD. Mol Cell 2011 0.75
222 4E-BPs at the crossroads of oncogenic MAPK and AKT signaling. Pigment Cell Melanoma Res 2010 0.75
223 Cancer genomics: the post-transcriptional era. Curr Opin Genet Dev 2013 0.75
224 Retraction. Macrophage inflammatory protein-1alpha and interferon-inducible protein 10 inhibit synergistically induced growth factor stimulation of MAP kinase activity and suppress phosphorylation of eukaryotic initiation factor 4E and 4E binding protein 1. Blood 2006 0.75