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Nuclear stiffening inhibits migration of invasive melanoma cells. Cell Mol Bioeng (2014) 0.83

Causes and consequences of nuclear envelope alterations in tumour progression. Eur J Cell Biol (2016) 0.83

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Extracellular matrix macromolecules: potential tools and targets in cancer gene therapy. Mol Cell Ther (2014) 0.78

Lamin A/C deficiency reduces circulating tumor cell resistance to fluid shear stress. Am J Physiol Cell Physiol (2015) 0.77

Promoter hypermethylation as a mechanism for Lamin A/C silencing in a subset of neuroblastoma cells. PLoS One (2017) 0.75

PKC-mediated phosphorylation of nuclear lamins at a single serine residue regulates interphase nuclear size in Xenopus and mammalian cells. Mol Biol Cell (2017) 0.75

Probing eukaryotic cell mechanics via mesoscopic simulations. PLoS Comput Biol (2017) 0.75

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Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nat Cell Biol (2007) 6.15

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The nuclear lamina comes of age. Nat Rev Mol Cell Biol (2005) 6.00

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Linear arrays of nuclear envelope proteins harness retrograde actin flow for nuclear movement. Science (2010) 3.53

SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton. Mol Cell Biol (2006) 3.39

Role of ANC-1 in tethering nuclei to the actin cytoskeleton. Science (2002) 3.38

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Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues. J Cell Sci (2001) 3.24

The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription. Genes Dev (2008) 3.23

Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin. J Cell Biol (2005) 3.17

Genome architecture: domain organization of interphase chromosomes. Cell (2013) 3.13

Nuclear shape, mechanics, and mechanotransduction. Circ Res (2008) 3.12

Interactions between nuclei and the cytoskeleton are mediated by SUN-KASH nuclear-envelope bridges. Annu Rev Cell Dev Biol (2010) 3.04

Lamins A and C but not lamin B1 regulate nuclear mechanics. J Biol Chem (2006) 3.02

UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans development. Development (1999) 2.96

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NUANCE, a giant protein connecting the nucleus and actin cytoskeleton. J Cell Sci (2002) 2.83

A bouquet makes ends meet. Nat Rev Mol Cell Biol (2001) 2.79

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LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins. Cell (2012) 2.79

Abnormal nuclear shape and impaired mechanotransduction in emerin-deficient cells. J Cell Biol (2005) 2.66

Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia. J Cell Biol (2010) 2.62

Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization. Proc Natl Acad Sci U S A (2009) 2.59

Intranuclear localization of snRNP antigens. J Cell Biol (1986) 2.54

Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A (2006) 2.53

Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness. Exp Cell Res (2008) 2.52

Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle. J Cell Sci (2005) 2.47

The nuclear envelope lamina network has elasticity and a compressibility limit suggestive of a molecular shock absorber. J Cell Sci (2004) 2.47

Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction. J Biol Chem (2000) 2.46

Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host. Nat Rev Cancer (2013) 2.41

LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation. Cell (2013) 2.38

ANChors away: an actin based mechanism of nuclear positioning. J Cell Sci (2003) 2.35

PML nuclear bodies: dynamic sensors of DNA damage and cellular stress. Bioessays (2004) 2.32

Nuclear mechanics during cell migration. Curr Opin Cell Biol (2010) 2.32

Interphase nuclear envelope lamins form a discontinuous network that interacts with only a fraction of the chromatin in the nuclear periphery. Cell (1990) 2.32

Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeleton. Exp Cell Res (2004) 2.27

Nuclear pores form de novo from both sides of the nuclear envelope. Science (2006) 2.24

Nesprin-1alpha self-associates and binds directly to emerin and lamin A in vitro. FEBS Lett (2002) 2.24

Identification of differentially expressed proteins in ovarian cancer using high-density protein microarrays. Proc Natl Acad Sci U S A (2007) 2.22

Nuclear neighborhoods and gene expression. Curr Opin Genet Dev (2009) 2.21

The interaction between nesprins and sun proteins at the nuclear envelope is critical for force transmission between the nucleus and cytoskeleton. J Biol Chem (2011) 2.21

Power-law rheology of isolated nuclei with deformation mapping of nuclear substructures. Biophys J (2005) 2.19

Contribution of the nucleus to the mechanical properties of endothelial cells. J Biomech (2002) 2.18

Micro-organization and visco-elasticity of the interphase nucleus revealed by particle nanotracking. J Cell Sci (2004) 2.17

Bringing KASH under the SUN: the many faces of nucleo-cytoskeletal connections. J Cell Biol (2009) 2.16

Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope. Mol Biol Cell (2005) 2.15

Control of basement membrane remodeling and epithelial branching morphogenesis in embryonic lung by Rho and cytoskeletal tension. Dev Dyn (2005) 2.13

Subnuclear organelles: new insights into form and function. Trends Cell Biol (2005) 2.10

Viscoelastic properties of the cell nucleus. Biochem Biophys Res Commun (2000) 2.08

Nuclear envelope disorganization in fibroblasts from lipodystrophic patients with heterozygous R482Q/W mutations in the lamin A/C gene. J Cell Sci (2001) 2.07

Myne-1, a spectrin repeat transmembrane protein of the myocyte inner nuclear membrane, interacts with lamin A/C. J Cell Sci (2002) 2.02

Nuclear positioning. Cell (2013) 2.01

Nuclear titin interacts with A- and B-type lamins in vitro and in vivo. J Cell Sci (2006) 1.99

Lamin-dependent localization of UNC-84, a protein required for nuclear migration in Caenorhabditis elegans. Mol Biol Cell (2002) 1.98

Nucleoplasmic beta-actin exists in a dynamic equilibrium between low-mobility polymeric species and rapidly diffusing populations. J Cell Biol (2006) 1.98

Dysfunctional connections between the nucleus and the actin and microtubule networks in laminopathic models. Biophys J (2008) 1.92

The nuclear envelope protein Matefin/SUN-1 is required for homologous pairing in C. elegans meiosis. Dev Cell (2007) 1.91

Nuclear export of actin: a novel mechanism regulating the subcellular localization of a major cytoskeletal protein. EMBO J (1998) 1.89

Lamin A/C and emerin regulate MKL1-SRF activity by modulating actin dynamics. Nature (2013) 1.89

A novel role for the nuclear membrane protein emerin in association of the centrosome to the outer nuclear membrane. J Cell Biol (2007) 1.87

When lamins go bad: nuclear structure and disease. Cell (2013) 1.84

Functional association of Sun1 with nuclear pore complexes. J Cell Biol (2007) 1.81

TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton. J Cell Sci (2008) 1.80

Nuclear envelope proteomics: novel integral membrane proteins of the inner nuclear membrane. Proc Natl Acad Sci U S A (2001) 1.79

Proteins that bind A-type lamins: integrating isolated clues. J Cell Sci (2004) 1.79

The nuclear lamins: flexibility in function. Nat Rev Mol Cell Biol (2012) 1.76

Mechanotransduction gone awry. Nat Rev Mol Cell Biol (2009) 4.00

Nuclear shape, mechanics, and mechanotransduction. Circ Res (2008) 3.12

Nuclear mechanics during cell migration. Curr Opin Cell Biol (2010) 2.32

Prelamin A and lamin A appear to be dispensable in the nuclear lamina. J Clin Invest (2006) 2.23

The interaction between nesprins and sun proteins at the nuclear envelope is critical for force transmission between the nucleus and cytoskeleton. J Biol Chem (2011) 2.21

Lamin A/C and emerin regulate MKL1-SRF activity by modulating actin dynamics. Nature (2013) 1.89

Thioredoxin-independent regulation of metabolism by the alpha-arrestin proteins. J Biol Chem (2009) 1.69

Increased mechanosensitivity and nuclear stiffness in Hutchinson-Gilford progeria cells: effects of farnesyltransferase inhibitors. Aging Cell (2008) 1.61

A three-dimensional viscoelastic model for cell deformation with experimental verification. Biophys J (2003) 1.42

Nuclear envelope composition determines the ability of neutrophil-type cells to passage through micron-scale constrictions. J Biol Chem (2013) 1.40

Towards an integrated understanding of the structure and mechanics of the cell nucleus. Bioessays (2008) 1.35

Focal adhesion kinase signaling regulates cardiogenesis of embryonic stem cells. J Biol Chem (2005) 1.33

Lamins at a glance. J Cell Sci (2012) 1.30

Cell-surface sensors for real-time probing of cellular environments. Nat Nanotechnol (2011) 1.28

An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria. Hum Mol Genet (2010) 1.26

Direct synthesis of lamin A, bypassing prelamin a processing, causes misshapen nuclei in fibroblasts but no detectable pathology in mice. J Biol Chem (2010) 1.24

Cell nuclei spin in the absence of lamin b1. J Biol Chem (2007) 1.22

Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling. Hum Mol Genet (2013) 1.17

Keeping the LINC: the importance of nucleocytoskeletal coupling in intracellular force transmission and cellular function. Biochem Soc Trans (2011) 1.11

Nuclear mechanics in disease. Annu Rev Biomed Eng (2011) 1.10

Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect. Proc Natl Acad Sci U S A (2011) 1.10

Biochemical and mechanical dysfunction in a mouse model of desmin-related myopathy. Circ Res (2009) 1.02

Attenuated hypertrophic response to pressure overload in a lamin A/C haploinsufficiency mouse. J Mol Cell Cardiol (2009) 0.99

Design of a microfluidic device to quantify dynamic intra-nuclear deformation during cell migration through confining environments. Integr Biol (Camb) (2015) 0.88

Experimental techniques for study of chromatin mechanics in intact nuclei and living cells. Chromosome Res (2008) 0.85

Biophysical assays to probe the mechanical properties of the interphase cell nucleus: substrate strain application and microneedle manipulation. J Vis Exp (2011) 0.83

Assays to measure nuclear mechanics in interphase cells. Curr Protoc Cell Biol (2012) 0.79

Altered mechanical properties of the nucleus in disease. Methods Cell Biol (2010) 0.79

Three-dimensional cardiac architecture determined by two-photon microtomy. J Biomed Opt (2009) 0.77

Another broken heart: loss of lamina-associated polypeptide 2alpha causes systolic dysfunction. Circ Res (2010) 0.75

Signaling pathways that influence extracellular remodeling. J Card Fail (2002) 0.75