Published in J Biol Chem on April 19, 2004
Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay. Mol Cell (2011) 2.73
RNA interference knockdown of hU2AF35 impairs cell cycle progression and modulates alternative splicing of Cdc25 transcripts. Mol Biol Cell (2006) 1.49
New connections between splicing and human disease. Trends Genet (2012) 1.39
In vivo requirement of the small subunit of U2AF for recognition of a weak 3' splice site. Mol Cell Biol (2006) 1.33
The (in)dependence of alternative splicing and gene duplication. PLoS Comput Biol (2007) 1.17
Expression proteomics of UPF1 knockdown in HeLa cells reveals autoregulation of hnRNP A2/B1 mediated by alternative splicing resulting in nonsense-mediated mRNA decay. BMC Genomics (2010) 1.07
Splicing factors SF1 and U2AF associate in extraspliceosomal complexes. Mol Cell Biol (2008) 1.00
Allele-specific recognition of the 3' splice site of INS intron 1. Hum Genet (2010) 0.94
Molecular characterization and phylogeny of U2AF35 homologs in plants. Plant Physiol (2006) 0.91
Alternative splicing and gene duplication in the evolution of the FoxP gene subfamily. Mol Biol Evol (2010) 0.86
Analysis of mutant phenotypes and splicing defects demonstrates functional collaboration between the large and small subunits of the essential splicing factor U2AF in vivo. Mol Biol Cell (2004) 0.85
Identification of U2AF(35)-dependent exons by RNA-Seq reveals a link between 3' splice-site organization and activity of U2AF-related proteins. Nucleic Acids Res (2015) 0.82
The evolutionary fate of alternatively spliced homologous exons after gene duplication. Genome Biol Evol (2015) 0.81
Optimal antisense target reducing INS intron 1 retention is adjacent to a parallel G quadruplex. Nucleic Acids Res (2014) 0.80
Evolution of selenophosphate synthetases: emergence and relocation of function through independent duplications and recurrent subfunctionalization. Genome Res (2015) 0.78
Exon-centric regulation of ATM expression is population-dependent and amenable to antisense modification by pseudoexon targeting. Sci Rep (2016) 0.77
Generation of a panel of antibodies against proteins encoded on human chromosome 21. J Negat Results Biomed (2010) 0.75
The Evolutionary Relationship between Alternative Splicing and Gene Duplication. Front Genet (2017) 0.75
Alternative splicing of U2AF1 reveals a shared repression mechanism for duplicated exons. Nucleic Acids Res (2016) 0.75
A SLM2 Feedback Pathway Controls Cortical Network Activity and Mouse Behavior. Cell Rep (2016) 0.75
The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem (2009) 40.90
The genome sequence of the malaria mosquito Anopheles gambiae. Science (2002) 20.36
Cyclical DNA methylation of a transcriptionally active promoter. Nature (2008) 7.62
Alternative splicing and genome complexity. Nat Genet (2001) 7.30
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype. Genome Biol (2007) 6.41
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations. Cell (2012) 6.07
Transient cyclical methylation of promoter DNA. Nature (2008) 5.19
Nucleosome positioning as a determinant of exon recognition. Nat Struct Mol Biol (2009) 5.14
DELLY: structural variant discovery by integrated paired-end and split-read analysis. Bioinformatics (2012) 4.79
Dissecting the genomic complexity underlying medulloblastoma. Nature (2012) 4.77
High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer. Genome Biol (2007) 4.70
Replicative senescence of mesenchymal stem cells: a continuous and organized process. PLoS One (2008) 4.37
Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood. Exp Hematol (2005) 4.27
Species-specific transcription in mice carrying human chromosome 21. Science (2008) 4.03
A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA). RNA (2006) 3.71
Statistical issues in the analysis of Illumina data. BMC Bioinformatics (2008) 3.66
Accounting for technical noise in single-cell RNA-seq experiments. Nat Methods (2013) 3.61
ASD: a bioinformatics resource on alternative splicing. Nucleic Acids Res (2006) 3.60
A neutral model of transcriptome evolution. PLoS Biol (2004) 3.44
The digital MIQE guidelines: Minimum Information for Publication of Quantitative Digital PCR Experiments. Clin Chem (2013) 3.38
Optimization of oligonucleotide-based DNA microarrays. Nucleic Acids Res (2002) 3.36
Polypyrimidine tract binding protein modulates efficiency of polyadenylation. Mol Cell Biol (2004) 3.28
Preliminary findings for two new measures of social and role functioning in the prodromal phase of schizophrenia. Schizophr Bull (2007) 3.15
Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer. Cancer Cell (2013) 3.08
Regulation of Fas alternative splicing by antagonistic effects of TIA-1 and PTB on exon definition. Mol Cell (2005) 2.99
Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs. Cell (2009) 2.98
The schizophrenia prodrome revisited: a neurodevelopmental perspective. Schizophr Bull (2003) 2.67
Aging and replicative senescence have related effects on human stem and progenitor cells. PLoS One (2009) 2.62
MicroRNA signatures predict oestrogen receptor, progesterone receptor and HER2/neu receptor status in breast cancer. Breast Cancer Res (2009) 2.59
Intron removal requires proofreading of U2AF/3' splice site recognition by DEK. Science (2006) 2.52
The spliceosome as a target of novel antitumour drugs. Nat Rev Drug Discov (2012) 2.51
MBNL proteins repress ES-cell-specific alternative splicing and reprogramming. Nature (2013) 2.49
Diverse roles of hnRNP L in mammalian mRNA processing: a combined microarray and RNAi analysis. RNA (2007) 2.48
Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A. Genes Dev (2011) 2.45
Generalized and specific neurocognitive deficits in prodromal schizophrenia. Biol Psychiatry (2005) 2.43
RBM5/Luca-15/H37 regulates Fas alternative splice site pairing after exon definition. Mol Cell (2008) 2.39
The splicing regulator TIA-1 interacts with U1-C to promote U1 snRNP recruitment to 5' splice sites. EMBO J (2002) 2.33
Building specificity with nonspecific RNA-binding proteins. Nat Struct Mol Biol (2005) 2.31
Vertebrate-type intron-rich genes in the marine annelid Platynereis dumerilii. Science (2005) 2.31
The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice. J Clin Invest (2011) 2.30
New androgen receptor genomic targets show an interaction with the ETS1 transcription factor. EMBO Rep (2007) 2.17
A consensus prognostic gene expression classifier for ER positive breast cancer. Genome Biol (2006) 2.17
Dynamic association of RNA-editing enzymes with the nucleolus. J Cell Sci (2003) 2.14
PACK: Profile Analysis using Clustering and Kurtosis to find molecular classifiers in cancer. Bioinformatics (2006) 2.12
Intracellular macromolecular mobility measured by fluorescence recovery after photobleaching with confocal laser scanning microscopes. Mol Biol Cell (2004) 2.10
Homodirectional changes in transcriptome composition and mRNA translation induced by rapamycin and heat shock. Nat Struct Biol (2003) 1.95
Endostatin's antiangiogenic signaling network. Mol Cell (2004) 1.95
Splicing regulation at the second catalytic step by Sex-lethal involves 3' splice site recognition by SPF45. Cell (2002) 1.94
Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway. Nat Cell Biol (2012) 1.88
Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36. Nat Struct Mol Biol (2011) 1.85
The emerging role of splicing factors in cancer. EMBO Rep (2008) 1.83
Genome-wide analysis of alternative pre-mRNA splicing. J Biol Chem (2007) 1.78
CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors. Genome Res (2010) 1.77
The expanding transcriptome: the genome as the 'Book of Sand'. EMBO J (2006) 1.73
Direct and indirect effects of H-NS and Fis on global gene expression control in Escherichia coli. Nucleic Acids Res (2010) 1.71
Developmentally regulated switching of titin size alters myofibrillar stiffness in the perinatal heart. Circ Res (2004) 1.70
The intranuclear mobility of messenger RNA binding proteins is ATP dependent and temperature sensitive. J Cell Biol (2002) 1.68
Can antidepressants be used to treat the schizophrenia prodrome? Results of a prospective, naturalistic treatment study of adolescents. J Clin Psychiatry (2007) 1.67
Anterior interbody fusion of the cervical spine with Zero-P spacer: prospective comparative study-clinical and radiological results at a minimum 2 years after surgery. Spine (Phila Pa 1976) (2013) 1.65
Hematopoietic progenitor cells and cellular microenvironment: behavioral and molecular changes upon interaction. Stem Cells (2005) 1.62
Treatment of thoracolumbar trauma by short-segment percutaneous transpedicular screw instrumentation: prospective comparative study with a minimum 2-year follow-up. J Neurosurg Spine (2013) 1.61
The need for transparency and good practices in the qPCR literature. Nat Methods (2013) 1.58
Association of ESR1 gene tagging SNPs with breast cancer risk. Hum Mol Genet (2009) 1.58
Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF. Nature (2011) 1.57
Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles. Nat Biotechnol (2003) 1.57
Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling. Cancer Res (2004) 1.56
Aberration-free three-dimensional multiphoton imaging of neuronal activity at kHz rates. Proc Natl Acad Sci U S A (2012) 1.55
Chemical chaperones reduce endoplasmic reticulum stress and prevent mutant HFE aggregate formation. J Biol Chem (2007) 1.55
Macromolecular mobility inside the cell nucleus. Trends Cell Biol (2002) 1.53
Molecular evidence for stem cell function of the slow-dividing fraction among human hematopoietic progenitor cells by genome-wide analysis. Blood (2004) 1.51
Decrypting the genome's alternative messages. Curr Opin Cell Biol (2009) 1.49
Tissue-specific splicing factor gene expression signatures. Nucleic Acids Res (2008) 1.49
RNA interference knockdown of hU2AF35 impairs cell cycle progression and modulates alternative splicing of Cdc25 transcripts. Mol Biol Cell (2006) 1.49
Genome-wide identification of functionally distinct subsets of cellular mRNAs associated with two nucleocytoplasmic-shuttling mammalian splicing factors. Genome Biol (2006) 1.49
Nonspecific and attenuated negative symptoms in patients at clinical high-risk for schizophrenia. Schizophr Res (2004) 1.49
miChip: an array-based method for microRNA expression profiling using locked nucleic acid capture probes. Nat Protoc (2008) 1.43
Transcriptional complexes engaged by apo-estrogen receptor-alpha isoforms have divergent outcomes. EMBO J (2004) 1.42
Nuclear hormone 1α,25-dihydroxyvitamin D3 elicits a genome-wide shift in the locations of VDR chromatin occupancy. Nucleic Acids Res (2011) 1.38
Clastosome: a subtype of nuclear body enriched in 19S and 20S proteasomes, ubiquitin, and protein substrates of proteasome. Mol Biol Cell (2002) 1.38
U2AF-homology motif interactions are required for alternative splicing regulation by SPF45. Nat Struct Mol Biol (2007) 1.38
A variational Bayesian mixture modelling framework for cluster analysis of gene-expression data. Bioinformatics (2005) 1.36
Multiple mechanisms induce transcriptional silencing of a subset of genes, including oestrogen receptor alpha, in response to deacetylase inhibition by valproic acid and trichostatin A. Oncogene (2005) 1.36
The assessment of "prodromal schizophrenia": unresolved issues and future directions. Schizophr Bull (2003) 1.36
Life cycle transcriptome of the malaria mosquito Anopheles gambiae and comparison with the fruitfly Drosophila melanogaster. Proc Natl Acad Sci U S A (2007) 1.36
In vivo recruitment of exon junction complex proteins to transcription sites in mammalian cell nuclei. RNA (2004) 1.35
The Ewing sarcoma protein regulates DNA damage-induced alternative splicing. Mol Cell (2011) 1.33
Kaposi's sarcoma herpesvirus microRNAs target caspase 3 and regulate apoptosis. PLoS Pathog (2011) 1.33
In vivo requirement of the small subunit of U2AF for recognition of a weak 3' splice site. Mol Cell Biol (2006) 1.33
Primer sequence disclosure: a clarification of the MIQE guidelines. Clin Chem (2011) 1.32
SUMO-1 modification alters ADAR1 editing activity. Mol Biol Cell (2005) 1.32
An efficient method for genome-wide polyadenylation site mapping and RNA quantification. Nucleic Acids Res (2013) 1.30
The DEXD/H-box RNA helicase RHII/Gu is a co-factor for c-Jun-activated transcription. EMBO J (2002) 1.30
Multiple epigenetic mechanisms and the piRNA pathway enforce LINE1 silencing during adult spermatogenesis. Mol Cell (2013) 1.29
The spliceosome: a self-organized macromolecular machine in the nucleus? Trends Cell Biol (2009) 1.29
Comparison of 3 fusion techniques in the treatment of the degenerative cervical spine disease. Is stand-alone autograft really the "gold standard?": prospective study with 2-year follow-up. Spine (Phila Pa 1976) (2012) 1.28
Global analysis of estrogen receptor beta binding to breast cancer cell genome reveals an extensive interplay with estrogen receptor alpha for target gene regulation. BMC Genomics (2011) 1.28