Published in Nature on April 22, 2004
Genomic imprinting: the emergence of an epigenetic paradigm. Nat Rev Genet (2011) 3.10
Contribution of intragenic DNA methylation in mouse gametic DNA methylomes to establish oocyte-specific heritable marks. PLoS Genet (2012) 2.89
Mammalian genomic imprinting. Cold Spring Harb Perspect Biol (2011) 2.59
Genomic imprinting: employing and avoiding epigenetic processes. Genes Dev (2009) 2.26
Maternal control of early mouse development. Development (2010) 2.13
Genomic imprinting in mammals: emerging themes and established theories. PLoS Genet (2006) 1.99
A secreted protein promotes cleavage furrow maturation during cytokinesis. Curr Biol (2011) 1.88
Novel epigenetic mechanisms that control pluripotency and quiescence of adult bone marrow-derived Oct4(+) very small embryonic-like stem cells. Leukemia (2009) 1.80
Nonallelic transvection of multiple imprinted loci is organized by the H19 imprinting control region during germline development. Genes Dev (2009) 1.68
Androgenetic haploid embryonic stem cells produce live transgenic mice. Nature (2012) 1.51
Generation of viable male and female mice from two fathers. Biol Reprod (2010) 1.46
Ascorbic acid improves pluripotency of human parthenogenetic embryonic stem cells through modifying imprinted gene expression in the Dlk1-Dio3 region. Stem Cell Res Ther (2015) 1.38
A differential dosage hypothesis for parental effects in seed development. Plant Cell (2004) 1.37
The sperm nucleus: chromatin, RNA, and the nuclear matrix. Reproduction (2010) 1.18
Epiblast/germ line hypothesis of cancer development revisited: lesson from the presence of Oct-4+ cells in adult tissues. Stem Cell Rev (2010) 1.17
Inferring the choreography of parental genomes during fertilization from ultralarge-scale whole-transcriptome analysis. Genes Dev (2013) 1.11
Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease. Brain (2008) 1.06
Unfaithful maintenance of methylation imprints due to loss of maternal nuclear Dnmt1 during somatic cell nuclear transfer. PLoS One (2011) 1.04
Endosperm gene imprinting and seed development. Curr Opin Genet Dev (2007) 1.02
The role of centrosomes in mammalian fertilization and its significance for ICSI. Mol Hum Reprod (2009) 1.01
Very small embryonic/epiblast-like stem cells: a missing link to support the germ line hypothesis of cancer development? Am J Pathol (2009) 1.01
Multiplex parenting: IVG and the generations to come. J Med Ethics (2014) 0.95
Growth of mouse oocytes to maturity from premeiotic germ cells in vitro. PLoS One (2012) 0.93
Efficient CRISPR/Cas9-mediated biallelic gene disruption and site-specific knockin after rapid selection of highly active sgRNAs in pigs. Sci Rep (2015) 0.92
A phylogenetic approach to test for evidence of parental conflict or gene duplications associated with protein-encoding imprinted orthologous genes in placental mammals. Mamm Genome (2010) 0.91
The role of maternal-specific H3K9me3 modification in establishing imprinted X-chromosome inactivation and embryogenesis in mice. Nat Commun (2014) 0.91
Paternal RNA contributions in the Caenorhabditis elegans zygote. EMBO J (2014) 0.90
Polycomb group gene function in sexual and asexual seed development in angiosperms. Sex Plant Reprod (2009) 0.89
An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution. Science (2012) 0.88
Embryos and pseudoembryos: parthenotes, reprogrammed oocytes and headless clones. J Med Ethics (2007) 0.87
p53 suppresses tetraploid development in mice. Sci Rep (2015) 0.85
Patient-specific pluripotent stem cells: promises and challenges. Nat Rev Endocrinol (2009) 0.85
Parthenogenesis-derived multipotent stem cells adapted for tissue engineering applications. Methods (2008) 0.85
Different yet similar: evolution of imprinting in flowering plants and mammals. F1000Prime Rep (2014) 0.85
Oocyte-specific deletion of complex and hybrid N-glycans leads to defects in preovulatory follicle and cumulus mass development. Reproduction (2008) 0.84
Unisexual reproduction drives evolution of eukaryotic microbial pathogens. PLoS Pathog (2013) 0.83
Functional neuronal cells generated by human parthenogenetic stem cells. PLoS One (2012) 0.83
Artificial gametes from stem cells. Clin Exp Reprod Med (2015) 0.81
Long noncoding RNAs in imprinting and X chromosome inactivation. Biomolecules (2014) 0.81
Restoration of Dlk1 and Rtl1 is necessary but insufficient to rescue lethality in intergenic differentially methylated region (IG-DMR)-deficient mice. J Biol Chem (2010) 0.80
Parent-of-origin effects on genome-wide DNA methylation in the Cape honey bee (Apis mellifera capensis) may be confounded by allele-specific methylation. BMC Genomics (2016) 0.80
Expression of major histocompatibility complex class I proteins and their antigen processing chaperones in mouse embryonic stem cells from fertilized and parthenogenetic embryos. Tissue Antigens (2008) 0.79
Transcriptional profiling by RNA-Seq of peri-attachment porcine embryos generated by a variety of assisted reproductive technologies. Physiol Genomics (2013) 0.79
Downregulation of H19 improves the differentiation potential of mouse parthenogenetic embryonic stem cells. Stem Cells Dev (2011) 0.79
Genomic imprinting: mice without a father. Nature (2004) 0.78
Effects of chemical combinations on the parthenogenetic activation of mouse oocytes. Exp Ther Med (2013) 0.78
Haploid genomes illustrate epigenetic constraints and gene dosage effects in mammals. Epigenetics Chromatin (2013) 0.77
Igf2-H19, an Imprinted Tandem Yin-Yanggene and its Emerging Role in Development, Proliferation of Pluripotent Stem Cells, Senescence and Cancerogenesis. J Stem Cell Res Ther (2012) 0.77
Proteomic profiling of rabbit embryonic stem cells derived from parthenotes and fertilized embryos. PLoS One (2013) 0.77
Will artificial gametes end infertility? Health Care Anal (2015) 0.77
Depletion of Key Meiotic Genes and Transcriptome-Wide Abiotic Stress Reprogramming Mark Early Preparatory Events Ahead of Apomeiotic Transition. Front Plant Sci (2016) 0.76
Current protocols in the generation of pluripotent stem cells: theoretical, methodological and clinical considerations. Stem Cells Cloning (2009) 0.76
Parthenogenesis and Human Assisted Reproduction. Stem Cells Int (2015) 0.76
Impact of sperm DNA chromatin in the clinic. J Assist Reprod Genet (2015) 0.76
Time to reconsider stem cell induction strategies. Cells (2012) 0.76
Imprinted Zac1 in neural stem cells. World J Stem Cells (2015) 0.76
Birth of fertile bimaternal offspring following intracytoplasmic injection of parthenogenetic haploid embryonic stem cells. Cell Res (2015) 0.76
Parentally imprinted genes regulate hematopoiesis-new evidence from the Dlk1-Gtl2 locus. Stem Cell Investig (2016) 0.75
Sexual reproduction with variable mating systems can resist asexuality in a rock-paper-scissors dynamics. R Soc Open Sci (2015) 0.75
Evolution of sexuality: biology and behavior. Proc (Bayl Univ Med Cent) (2005) 0.75
Molecules and mechanisms controlling the active DNA demethylation of the mammalian zygotic genome. Protein Cell (2014) 0.75
Histocompatible parthenogenetic embryonic stem cells as a potential source for regenerative medicine. J Mamm Ova Res (2012) 0.75
The Influence of Polyploidy and Genome Composition on Genomic Imprinting in Mice. J Biol Chem (2016) 0.75
Inducing human parthenogenetic embryonic stem cells into islet‑like clusters. Mol Med Rep (2014) 0.75
Rapidly generating knockout mice from H19-Igf2 engineered androgenetic haploid embryonic stem cells. Cell Discov (2015) 0.75
Characterization of Embryo Transcriptome of Gynogenetic Olive Flounder Paralichthys olivaceus. Mar Biotechnol (NY) (2016) 0.75
The effects of melatonin on bovine uniparental embryos development in vitro and the hormone secretion of COCs. PeerJ (2017) 0.75
A versatile genetic tool: haploid cells. Stem Cell Res Ther (2017) 0.75
Vigor of survival determinism: subtle evolutionary gradualism interspersed with robust phylogenetic leaping. Theory Biosci (2017) 0.75
Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes. Nature (2008) 10.11
A highly annotated whole-genome sequence of a Korean individual. Nature (2009) 6.91
New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature (2008) 6.82
Blimp1 is a critical determinant of the germ cell lineage in mice. Nature (2005) 5.49
The fine-scale and complex architecture of human copy-number variation. Am J Hum Genet (2008) 5.08
Beneficial effects of subcutaneous fat transplantation on metabolism. Cell Metab (2008) 5.07
Evidence for a role of developmental genes in the origin of obesity and body fat distribution. Proc Natl Acad Sci U S A (2006) 4.81
An improved single-cell cDNA amplification method for efficient high-density oligonucleotide microarray analysis. Nucleic Acids Res (2006) 4.26
A transforming KIF5B and RET gene fusion in lung adenocarcinoma revealed from whole-genome and transcriptome sequencing. Genome Res (2011) 4.15
A public resource facilitating clinical use of genomes. Proc Natl Acad Sci U S A (2012) 3.72
Discovery of common Asian copy number variants using integrated high-resolution array CGH and massively parallel DNA sequencing. Nat Genet (2010) 3.49
The genome sequence of Xanthomonas oryzae pathovar oryzae KACC10331, the bacterial blight pathogen of rice. Nucleic Acids Res (2005) 3.37
Extensive genomic and transcriptional diversity identified through massively parallel DNA and RNA sequencing of eighteen Korean individuals. Nat Genet (2011) 2.74
Sixty-five gene-based risk score classifier predicts overall survival in hepatocellular carcinoma. Hepatology (2012) 2.40
E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition. Int J Cancer (2008) 2.04
Unregulated expression of the imprinted genes H19 and Igf2r in mouse uniparental fetuses. J Biol Chem (2002) 2.01
Oocyte growth-dependent progression of maternal imprinting in mice. Genes Cells (2006) 1.84
Gene expression signature-based prognostic risk score in gastric cancer. Clin Cancer Res (2011) 1.83
A tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip. Nucleic Acids Res (2010) 1.83
Identification of a cholangiocarcinoma-like gene expression trait in hepatocellular carcinoma. Cancer Res (2010) 1.82
Dual inhibition of tumor energy pathway by 2-deoxyglucose and metformin is effective against a broad spectrum of preclinical cancer models. Mol Cancer Ther (2011) 1.81
Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy. Neoplasia (2011) 1.78
Deletion of Gtl2, imprinted non-coding RNA, with its differentially methylated region induces lethal parent-origin-dependent defects in mice. Hum Mol Genet (2009) 1.72
A systematic genome-wide screen for mutations affecting organogenesis in Medaka, Oryzias latipes. Mech Dev (2004) 1.65
Immunologic evaluation of personalized peptide vaccination for patients with advanced malignant glioma. Clin Cancer Res (2005) 1.65
Delayed laparoscopic subtotal cholecystectomy in acute cholecystitis with severe fibrotic adhesions. Surg Endosc (2008) 1.58
Tunnel position and relationship to postoperative knee laxity after double-bundle anterior cruciate ligament reconstruction with a transtibial technique. Am J Sports Med (2010) 1.55
A family-based association study after genome-wide linkage analysis identified two genetic loci for renal function in a Mongolian population. Kidney Int (2012) 1.54
Overexpressed cyclo-oxygenase-2 in the background liver is associated with the clinical course of hepatitis C virus-related cirrhosis patients after curative surgery for hepatocellular carcinoma. J Gastroenterol Hepatol (2007) 1.49
Tumor local chemohyperthermia using docetaxel-embedded magnetoliposomes: Interaction of chemotherapy and hyperthermia. J Gastroenterol Hepatol (2012) 1.47
Identification of potential driver genes in human liver carcinoma by genomewide screening. Cancer Res (2009) 1.45
The presence of the Y-chromosome, not the absence of the second X-chromosome, alters the mRNA levels stored in the fully grown XY mouse oocyte. PLoS One (2012) 1.42
Gene expression-based recurrence prediction of hepatitis B virus-related human hepatocellular carcinoma. Clin Cancer Res (2008) 1.41
Heat shock protein hsp72 is a negative regulator of apoptosis signal-regulating kinase 1. Mol Cell Biol (2002) 1.35
Prognostic biomarkers for esophageal adenocarcinoma identified by analysis of tumor transcriptome. PLoS One (2010) 1.33
Prognostic gene expression signature associated with two molecularly distinct subtypes of colorectal cancer. Gut (2011) 1.32
Development and validation of a prognostic gene-expression signature for lung adenocarcinoma. PLoS One (2012) 1.28
A prospective feasibility and safety study of laparoscopy-assisted distal gastrectomy for clinical stage I gastric cancer initiated by surgeons with much experience of open gastrectomy and laparoscopic surgery. Gastric Cancer (2012) 1.26
Respiration metabolism reduces oxidative and acid stress to improve long-term survival of Lactococcus lactis. Mol Microbiol (2004) 1.25
Antitumor activities of the targeted multi-tyrosine kinase inhibitor lenvatinib (E7080) against RET gene fusion-driven tumor models. Cancer Lett (2013) 1.22
Rapid replacement of somatic linker histones with the oocyte-specific linker histone H1foo in nuclear transfer. Dev Biol (2004) 1.22
Identification of radiation-specific responses from gene expression profile. Oncogene (2002) 1.16
Differences in torsional joint stiffness of the knee between genders: a human cadaveric study. Am J Sports Med (2006) 1.15
Genetic diagnosis of Duchenne and Becker muscular dystrophy using next-generation sequencing technology: comprehensive mutational search in a single platform. J Med Genet (2011) 1.14
Domain regulation of imprinting cluster in Kip2/Lit1 subdomain on mouse chromosome 7F4/F5: large-scale DNA methylation analysis reveals that DMR-Lit1 is a putative imprinting control region. Genome Res (2002) 1.13
Targeted disruption of hsp70.1 sensitizes to osmotic stress. EMBO Rep (2002) 1.13
Whole-exome sequencing identifies mutations of KIF22 in spondyloepimetaphyseal dysplasia with joint laxity, leptodactylic type. Am J Hum Genet (2011) 1.13
Sigmoid colon endometriosis treated with laparoscopy-assisted sigmoidectomy: significance of preoperative diagnosis. World J Gastroenterol (2007) 1.11
Activation of histone deacetylase 2 by inducible heat shock protein 70 in cardiac hypertrophy. Circ Res (2008) 1.10
FX: an RNA-Seq analysis tool on the cloud. Bioinformatics (2012) 1.10
Draft genome sequence of Streptomyces clavuligerus NRRL 3585, a producer of diverse secondary metabolites. J Bacteriol (2010) 1.10
Targeted sequencing of cancer-related genes in colorectal cancer using next-generation sequencing. PLoS One (2013) 1.10
A frameshift mutation of beta subunit of epithelial sodium channel in a case of isolated Liddle syndrome. J Hypertens (2002) 1.08
A microarray-based method for detecting methylated loci. J Hum Genet (2002) 1.07
XRCC1 genetic polymorphism and breast cancer risk. Pharmacogenetics (2002) 1.06
Three people can synchronize as coupled oscillators during sports activities. PLoS Comput Biol (2011) 1.05
Sulfonamide derivative, E7820, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium. Cancer Res (2002) 1.05
Exploring genomic profiles of hepatocellular carcinoma. Mol Carcinog (2011) 1.05
Therapeutic impact of leptin on diabetes, diabetic complications, and longevity in insulin-deficient diabetic mice. Diabetes (2011) 1.03
Evaluation of prognostic factors and scoring system in colonic perforation. World J Gastroenterol (2007) 1.03
A new 39-plex analysis method for SNPs including 15 blood group loci. Forensic Sci Int (2004) 1.03
FOXO3a turns the tumor necrosis factor receptor signaling towards apoptosis through reciprocal regulation of c-Jun N-terminal kinase and NF-kappaB. Arterioscler Thromb Vasc Biol (2007) 1.03
Significance of laparoscopic splenectomy in patients with hypersplenism. World J Surg (2007) 1.03
Nuclease A (Gbs0661), an extracellular nuclease of Streptococcus agalactiae, attacks the neutrophil extracellular traps and is needed for full virulence. Mol Microbiol (2013) 1.03
Reference-unbiased copy number variant analysis using CGH microarrays. Nucleic Acids Res (2010) 1.03
Iron chelation study in a normal human hepatocyte cell line suggests that tumor necrosis factor receptor-associated protein 1 (TRAP1) regulates production of reactive oxygen species. J Cell Biochem (2007) 1.02
Tuberin is a component of lipid rafts and mediates caveolin-1 localization: role of TSC2 in post-Golgi transport. Exp Cell Res (2004) 1.01
Cyclooxygenase-2 mRNA is up-regulated in cirrhotic or chronic hepatitis liver adjacent to hepatocellular carcinoma. J Gastroenterol Hepatol (2002) 1.00
Nocturnal knee pain increases with the severity of knee osteoarthritis, disturbing patient sleep quality. Arthritis Care Res (Hoboken) (2014) 0.99
HSP70 deficiency results in activation of c-Jun N-terminal Kinase, extracellular signal-regulated kinase, and caspase-3 in hyperosmolarity-induced apoptosis. J Biol Chem (2004) 0.98
Association of interleukin-6 promoter variant with bone mineral density in pre-menopausal women. J Hum Genet (2003) 0.98
Novel temperature-triggered liposome with high stability: formulation, in vitro evaluation, and in vivo study combined with high-intensity focused ultrasound (HIFU). J Control Release (2013) 0.97
An angiogenesis inhibitor E7820 shows broad-spectrum tumor growth inhibition in a xenograft model: possible value of integrin alpha2 on platelets as a biological marker. Clin Cancer Res (2004) 0.97
Reconstruction of nuclear receptor network reveals that NR2E3 is a novel upstream regulator of ESR1 in breast cancer. EMBO Mol Med (2011) 0.97
Relationship between patient-based outcome score and conventional objective outcome scales in post-operative total knee arthroplasty patients. Int Orthop (2013) 0.96
Forkhead factor, FOXO3a, induces apoptosis of endothelial cells through activation of matrix metalloproteinases. Arterioscler Thromb Vasc Biol (2007) 0.96
Ghrelin improves renal function in mice with ischemic acute renal failure. J Am Soc Nephrol (2005) 0.96
DNA methylation imprints on the IG-DMR of the Dlk1-Gtl2 domain in mouse male germline. FEBS Lett (2007) 0.96
Caveolin-1 activates Rab5 and enhances endocytosis through direct interaction. Biochem Biophys Res Commun (2008) 0.96
Tuberous sclerosis complex 2 loss-of-function mutation regulates reactive oxygen species production through Rac1 activation. Biochem Biophys Res Commun (2008) 0.96
Gene expression profile of megakaryocytes from human cord blood CD34(+) cells ex vivo expanded by thrombopoietin. Stem Cells (2002) 0.96
Expression of survivin mRNA associates with apoptosis, proliferation and histologically aggressive features in hepatocellular carcinoma. Oncol Rep (2004) 0.96
The femoral insertion of the anterior cruciate ligament: discrepancy between macroscopic and histological observations. Arthroscopy (2012) 0.95
Application of SYPRO Ruby- and Flamingo-stained polyacrylamide gels to Western blot analysis. Anal Biochem (2010) 0.95
Increased expression of DNA methyltransferase 3a in obese adipose tissue: studies with transgenic mice. Obesity (Silver Spring) (2009) 0.95
Glucocorticoid reamplification within cells intensifies NF-kappaB and MAPK signaling and reinforces inflammation in activated preadipocytes. Am J Physiol Endocrinol Metab (2009) 0.95
Genome-scale modeling and in silico analysis of ethanologenic bacteria Zymomonas mobilis. Biotechnol Bioeng (2010) 0.95
Abnormalities in cloned mice are not transmitted to the progeny. Genesis (2002) 0.94
Immunological evaluation of individualized peptide vaccination with a low dose of estramustine for HLA-A24+ HRPC patients. Prostate (2005) 0.94
Mouse parthenogenetic embryos with monoallelic H19 expression can develop to day 17.5 of gestation. Dev Biol (2002) 0.94
Metastatic osteosarcoma in the jejunum with intussusception: report of a case. Surg Today (2007) 0.93
Choline acetyltransferase G +4 A polymorphism confers a risk for Alzheimer's disease in concert with Apolipoprotein E epsilon4. Neurosci Lett (2004) 0.93
Osteochondral autograft transplantation for osteochondritis dissecans of the capitellum in nonthrowing athletes. Arthroscopy (2005) 0.93
Identification of a recurrent transforming UBR5-ZNF423 fusion gene in EBV-associated nasopharyngeal carcinoma. J Pathol (2013) 0.92
Leptin activates hepatic 5'-AMP-activated protein kinase through sympathetic nervous system and α1-adrenergic receptor: a potential mechanism for improvement of fatty liver in lipodystrophy by leptin. J Biol Chem (2012) 0.92
Spontaneous activation of pancreas trypsinogen in heat shock protein 70.1 knock-out mice. Pancreas (2005) 0.92
Comprehensive genomic analyses associate UGT8 variants with musical ability in a Mongolian population. J Med Genet (2012) 0.91
Targeting efficiency of a-1,3-galactosyl transferase gene in pig fetal fibroblast cells. Exp Mol Med (2003) 0.91