Published in BMC Dev Biol on May 03, 2006
A meta-analysis of human embryonic stem cells transcriptome integrated into a web-based expression atlas. Stem Cells (2007) 3.62
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Application of genome-wide single nucleotide polymorphism typing: simple association and beyond. PLoS Genet (2006) 2.02
Comparison of hybridization-based and sequencing-based gene expression technologies on biological replicates. BMC Genomics (2007) 1.77
Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions. Stem Cells (2010) 1.74
MicroRNA expression pattern of undifferentiated and differentiated human embryonic stem cells. Stem Cells Dev (2007) 1.65
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Silencing of core transcription factors in human EC cells highlights the importance of autocrine FGF signaling for self-renewal. BMC Dev Biol (2007) 1.21
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Differentiating human multipotent mesenchymal stromal cells regulate microRNAs: prediction of microRNA regulation by PDGF during osteogenesis. Exp Hematol (2008) 1.00
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GeneChip analysis of human embryonic stem cell differentiation into hemangioblasts: an in silico dissection of mixed phenotypes. Genome Biol (2007) 0.92
Self-renewal and differentiation capabilities are variable between human embryonic stem cell lines I3, I6 and BG01V. BMC Cell Biol (2009) 0.91
Genome wide profiling of dopaminergic neurons derived from human embryonic and induced pluripotent stem cells. Stem Cells Dev (2013) 0.91
Identification by automated screening of a small molecule that selectively eliminates neural stem cells derived from hESCs but not dopamine neurons. PLoS One (2009) 0.90
Expression patterns of cancer-testis antigens in human embryonic stem cells and their cell derivatives indicate lineage tracks. Stem Cells Int (2011) 0.89
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Contrasting expression of keratins in mouse and human embryonic stem cells. PLoS One (2008) 0.86
Transcripts that associate with the RNA binding protein, DEAD-END (DND1), in embryonic stem (ES) cells. BMC Mol Biol (2011) 0.84
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Human iPSC-Derived Immature Astroglia Promote Oligodendrogenesis by Increasing TIMP-1 Secretion. Cell Rep (2016) 0.80
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Differentiation-Coupled Induction of Human Cytomegalovirus Replication by Union of the Major Enhancer Retinoic Acid, Cyclic AMP, and NF-κB Response Elements. J Virol (2015) 0.77
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Genomic alterations in cultured human embryonic stem cells. Nat Genet (2005) 3.89
Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro. Lab Invest (1984) 3.86
The transcriptome profile of human embryonic stem cells as defined by SAGE. Stem Cells (2004) 3.78
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Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state. Stem Cells (2005) 3.16
Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells. Stem Cells (2005) 2.81
Differential requirements for Smad4 in TGFbeta-dependent patterning of the early mouse embryo. Development (2004) 2.28
MPSS profiling of human embryonic stem cells. BMC Dev Biol (2004) 2.17
Transforming growth factor-beta signaling in stem cells and cancer. Science (2005) 1.95
Gene expression signatures of seven individual human embryonic stem cell lines. Stem Cells (2005) 1.86
Comparative evaluation of various human feeders for prolonged undifferentiated growth of human embryonic stem cells. Stem Cells (2003) 1.83
Genetic analysis of the Müllerian-inhibiting substance signal transduction pathway in mammalian sexual differentiation. Genes Dev (1996) 1.75
Comparison of the gene expression profile of undifferentiated human embryonic stem cell lines and differentiating embryoid bodies. BMC Dev Biol (2005) 1.61
Properties of four human embryonic stem cell lines maintained in a feeder-free culture system. Dev Dyn (2004) 1.60
Assessing self-renewal and differentiation in human embryonic stem cell lines. Stem Cells (2005) 1.58
Properties of pluripotent human embryonic stem cells BG01 and BG02. Stem Cells (2004) 1.36
BG01V: a variant human embryonic stem cell line which exhibits rapid growth after passaging and reliable dopaminergic differentiation. Restor Neurol Neurosci (2004) 1.22
Monitoring early differentiation events in human embryonic stem cells by massively parallel signature sequencing and expressed sequence tag scan. Stem Cells Dev (2004) 1.15
Monitoring differentiation of human embryonic stem cells using real-time PCR. Stem Cells (2005) 1.11
NTera2: a model system to study dopaminergic differentiation of human embryonic stem cells. Stem Cells Dev (2005) 1.08
An evolutionary conserved role of Wnt signaling in stem cell fate decision. Dev Biol (2005) 0.98
Development of antibodies to human embryonic stem cell antigens. BMC Dev Biol (2005) 0.85
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements. Nat Biotechnol (2006) 30.90
Mapping the genetic architecture of gene expression in human liver. PLoS Biol (2008) 19.44
Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron (2003) 14.03
High-resolution genomic profiling of chromosomal aberrations using Infinium whole-genome genotyping. Genome Res (2006) 10.45
Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils. Science (2005) 8.86
High-throughput DNA methylation profiling using universal bead arrays. Genome Res (2006) 8.05
Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells. Nat Biotechnol (2012) 7.37
Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture. Cell Stem Cell (2011) 6.82
Whole-genome genotyping with the single-base extension assay. Nat Methods (2006) 6.66
BeadArray technology: enabling an accurate, cost-effective approach to high-throughput genotyping. Biotechniques (2002) 5.98
Identification of a target RNA motif for RNA-binding protein HuR. Proc Natl Acad Sci U S A (2004) 5.15
Regulatory networks define phenotypic classes of human stem cell lines. Nature (2008) 4.98
Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway. Proc Natl Acad Sci U S A (2004) 4.70
A novel, high-performance random array platform for quantitative gene expression profiling. Genome Res (2004) 4.32
A versatile assay for high-throughput gene expression profiling on universal array matrices. Genome Res (2004) 4.19
Superoxide flashes in single mitochondria. Cell (2008) 4.08
Differential allelic expression in the human genome: a robust approach to identify genetic and epigenetic cis-acting mechanisms regulating gene expression. PLoS Genet (2008) 3.92
Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits. Proc Natl Acad Sci U S A (2007) 3.91
Genomic alterations in cultured human embryonic stem cells. Nat Genet (2005) 3.89
LincRNA-p21 suppresses target mRNA translation. Mol Cell (2012) 3.87
Gene expression in human embryonic stem cell lines: unique molecular signature. Blood (2003) 3.73
A bioinformatic assay for pluripotency in human cells. Nat Methods (2011) 3.66
Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease. Proc Natl Acad Sci U S A (2004) 3.61
Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs. Cell Stem Cell (2011) 3.32
Differences between human and mouse embryonic stem cells. Dev Biol (2004) 3.30
Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice. J Neurochem (2002) 3.27
Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease. Trends Neurosci (2008) 3.25
AGEMAP: a gene expression database for aging in mice. PLoS Genet (2007) 3.22
Using RNA sample titrations to assess microarray platform performance and normalization techniques. Nat Biotechnol (2006) 3.13
Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons. Nat Neurosci (2008) 3.11
Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling. Blood (2007) 3.05
Research capacity. Enabling the genomic revolution in Africa. Science (2014) 3.05
Quantitative gene expression profiling in formalin-fixed, paraffin-embedded tissues using universal bead arrays. Am J Pathol (2004) 3.04
Genomic diversity of 2010 Haitian cholera outbreak strains. Proc Natl Acad Sci U S A (2012) 3.04
A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort. Genome Res (2011) 3.00
Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease. Proc Natl Acad Sci U S A (2009) 2.96
Recurrent variations in DNA methylation in human pluripotent stem cells and their differentiated derivatives. Cell Stem Cell (2012) 2.94
Human embryonic stem cells have a unique epigenetic signature. Genome Res (2006) 2.89
Identification and functional outcome of mRNAs associated with RNA-binding protein TIA-1. Mol Cell Biol (2005) 2.83
Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake. Proc Natl Acad Sci U S A (2003) 2.82
RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways. Proc Natl Acad Sci U S A (2008) 2.76
Human umbilical cord matrix stem cells: preliminary characterization and effect of transplantation in a rodent model of Parkinson's disease. Stem Cells (2005) 2.74
Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease. Nat Neurosci (2008) 2.67
Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. Nat Biotechnol (2004) 2.60
Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease. Nat Med (2007) 2.57
Comprehensive microRNA profiling reveals a unique human embryonic stem cell signature dominated by a single seed sequence. Stem Cells (2008) 2.52
"Control" laboratory rodents are metabolically morbid: why it matters. Proc Natl Acad Sci U S A (2010) 2.50
A call for standardized naming and reporting of human ESC and iPSC lines. Cell Stem Cell (2011) 2.48
Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation. Nat Med (2005) 2.46
Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease. J Neurochem (2002) 2.45
Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats. Hippocampus (2008) 2.44
The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies. Brain Res Rev (2008) 2.39
Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicol Appl Pharmacol (2007) 2.37
Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice. Proc Natl Acad Sci U S A (2003) 2.35
Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma. Free Radic Biol Med (2006) 2.32
Dopaminergic differentiation of human embryonic stem cells. Stem Cells (2004) 2.30
Soliciting strategies for developing cell-based reference materials to advance mesenchymal stromal cell research and clinical translation. Stem Cells Dev (2014) 2.27
Calcium orchestrates apoptosis. Nat Cell Biol (2003) 2.27
Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells. Proc Natl Acad Sci U S A (2007) 2.19
A controlled trial of reduced meal frequency without caloric restriction in healthy, normal-weight, middle-aged adults. Am J Clin Nutr (2007) 2.16
Accuracy of genome-wide imputation of untyped markers and impacts on statistical power for association studies. BMC Genet (2009) 2.16
Toll-like receptors in neurodegeneration. Brain Res Rev (2008) 2.15
GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism. Proc Natl Acad Sci U S A (2009) 2.15
Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease. J Neurosci (2002) 2.14
Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease. Neurobiol Dis (2007) 2.08
Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver. Genome Res (2010) 2.06
Toll-like receptor 3 inhibits memory retention and constrains adult hippocampal neurogenesis. Proc Natl Acad Sci U S A (2010) 2.05
Prophylactic treatment with paroxetine ameliorates behavioral deficits and retards the development of amyloid and tau pathologies in 3xTgAD mice. Exp Neurol (2007) 2.04
Acute kidney injury leads to inflammation and functional changes in the brain. J Am Soc Nephrol (2008) 2.03
Friedreich's ataxia induced pluripotent stem cells model intergenerational GAA⋅TTC triplet repeat instability. Cell Stem Cell (2010) 2.02
Long-term culture of human embryonic stem cells in feeder-free conditions. Dev Dyn (2004) 2.01
Toll-like receptor signaling in neural plasticity and disease. Trends Neurosci (2011) 2.01
Cell cycle activation linked to neuronal cell death initiated by DNA damage. Neuron (2004) 1.99
Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease. J Neurochem (2002) 1.99
Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets. Nat Med (2011) 1.97
Transient improvement in cognitive function and synaptic plasticity in rats following cancer chemotherapy. Clin Cancer Res (2006) 1.97
Gene therapy: can neural stem cells deliver? Nat Rev Neurosci (2006) 1.95
Caloric restriction and intermittent fasting: two potential diets for successful brain aging. Ageing Res Rev (2006) 1.94
A call to standardize teratoma assays used to define human pluripotent cell lines. Cell Stem Cell (2010) 1.93
A genome-wide association study identifies two new risk loci for Graves' disease. Nat Genet (2011) 1.92
Conversion of human fibroblasts to angioblast-like progenitor cells. Nat Methods (2012) 1.91
Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport. J Neurosci (2003) 1.91
Modulation of taste sensitivity by GLP-1 signaling. J Neurochem (2008) 1.89