Published in Cell Stress Chaperones on January 01, 2003
Heat shock protein 27: its potential role in vascular disease. Int J Exp Pathol (2006) 1.09
Functional SNPs in HSPA1A gene predict risk of coronary heart disease. PLoS One (2009) 1.07
HIV-1 infected monocyte-derived macrophages affect the human brain microvascular endothelial cell proteome: new insights into blood-brain barrier dysfunction for HIV-1-associated dementia. J Neuroimmunol (2007) 1.05
Transient ureteral obstruction prevents against kidney ischemia/reperfusion injury via hypoxia-inducible factor (HIF)-2α activation. PLoS One (2012) 0.87
The role of clusterin in retinal development and free radical damage. Br J Ophthalmol (2007) 0.87
Heat shock protein 27 overexpression mitigates cytokine-induced islet apoptosis and streptozotocin-induced diabetes. Endocrinology (2009) 0.85
Heat shock proteins in chronic kidney disease. Pediatr Nephrol (2010) 0.83
Zinc Supplementation with Polaprezinc Protects Mouse Hepatocytes against Acetaminophen-Induced Toxicity via Induction of Heat Shock Protein 70. J Clin Biochem Nutr (2009) 0.82
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Effects of Helicobacter pylori and Heat Shock Protein 70 on the Proliferation of Human Gastric Epithelial Cells. Gastroenterol Res Pract (2014) 0.75
Preconditioning crush increases the survival rate of motor neurons after spinal root avulsion. Neural Regen Res (2014) 0.75
Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome. Nat Cell Biol (2000) 5.24
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Negative regulation of the Apaf-1 apoptosome by Hsp70. Nat Cell Biol (2000) 3.05
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Hsp27 as a negative regulator of cytochrome C release. Mol Cell Biol (2002) 1.80
Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3. Oncogene (2000) 1.72
Heat shock proteins and cardiovascular pathophysiology. Physiol Rev (2001) 1.62
Heat shock proteins and cardiac protection. Cardiovasc Res (2001) 1.55
Bimoclomol: a nontoxic, hydroxylamine derivative with stress protein-inducing activity and cytoprotective effects. Nat Med (1997) 1.50
Apoptosis of endothelial cells precedes myocyte cell apoptosis in ischemia/reperfusion injury. Circulation (2001) 1.40
Estrogen signals to the preservation of endothelial cell form and function. J Biol Chem (2000) 1.33
Protection of neuronal cells from apoptosis by Hsp27 delivered with a herpes simplex virus-based vector. J Biol Chem (1999) 1.24
Single oral dose of geranylgeranylacetone induces heat-shock protein 72 and renders protection against ischemia/reperfusion injury in rat heart. Circulation (2001) 1.23
Different signaling pathways induce apoptosis in endothelial cells and cardiac myocytes during ischemia/reperfusion injury. Circ Res (2002) 1.18
Mechanisms of hypoxia-induced endothelial cell death. Role of p53 in apoptosis. J Biol Chem (1999) 1.18
Heat shock proteins delivered with a virus vector can protect cardiac cells against apoptosis as well as against thermal or hypoxic stress. J Mol Cell Cardiol (1999) 1.04
Suppression of stress kinase JNK is involved in HSP72-mediated protection of myogenic cells from transient energy deprivation. HSP72 alleviates the stewss-induced inhibition of JNK dephosphorylation. J Biol Chem (2000) 1.02
Stressful preconditioning and HSP70 overexpression attenuate proteotoxicity of cellular ATP depletion. Am J Physiol Cell Physiol (2002) 1.00
Sequence of the Chinese hamster small heat shock protein HSP27. Nucleic Acids Res (1990) 0.97
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Heat shock protein 27 delivered via a herpes simplex virus vector can protect neurons of the hippocampus against kainic-acid-induced cell loss. Brain Res Mol Brain Res (2003) 0.87
Early and delayed tolerance to simulated ischemia in heat-preconditioned endothelial cells: a role for HSP27. Am J Physiol (1998) 0.86
Overexpressed heat shock protein 70 attenuates hypoxic injury in coronary endothelial cells. J Mol Cell Cardiol (1998) 0.85
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Bimoclomol elevates heat shock protein 70 and cytoprotects rat neonatal cardiomyocytes. Eur J Pharmacol (2002) 0.80
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Gene delivery and gene therapy with herpes simplex virus-based vectors. Gene (2001) 0.79
Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science (2004) 15.91
PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death. Mol Cell (2009) 3.17
Voltage-gated sodium channel expression and potentiation of human breast cancer metastasis. Clin Cancer Res (2005) 1.99
Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress. J Neurochem (2006) 1.91
Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury. J Mol Cell Cardiol (2006) 1.83
STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis. J Biol Chem (2003) 1.79
Urocortin-II and urocortin-III are cardioprotective against ischemia reperfusion injury: an essential endogenous cardioprotective role for corticotropin releasing factor receptor type 2 in the murine heart. Endocrinology (2003) 1.76
Urocortin prevents mitochondrial permeability transition in response to reperfusion injury indirectly by reducing oxidative stress. Am J Physiol Heart Circ Physiol (2007) 1.70
A heterozygous effect for PINK1 mutations in Parkinson's disease? Ann Neurol (2006) 1.61
Antibodies to apolipoprotein A-I, high-density lipoprotein, and C-reactive protein are associated with disease activity in patients with systemic lupus erythematosus. Arthritis Rheum (2010) 1.60
Activation of CDK4 gene expression in human breast cancer cells by the Brn-3b POU family transcription factor. Cancer Biol Ther (2004) 1.57
Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury. Int J Cardiol (2011) 1.52
The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity. J Biol Chem (2002) 1.45
STAT-1: a novel regulator of apoptosis. Int J Exp Pathol (2003) 1.43
Dysregulation of histone acetylation in the APP/PS1 mouse model of Alzheimer's disease. J Alzheimers Dis (2009) 1.34
PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73. Mol Cell Biol (2004) 1.33
Role of the JAK-STAT pathway in myocardial injury. Trends Mol Med (2006) 1.32
Epigallocatechin-3-gallate inhibits STAT-1 activation and protects cardiac myocytes from ischemia/reperfusion-induced apoptosis. FASEB J (2004) 1.31
The neuroprotective effects of heat shock protein 27 overexpression in transgenic animals against kainate-induced seizures and hippocampal cell death. J Biol Chem (2003) 1.24
Different signaling pathways induce apoptosis in endothelial cells and cardiac myocytes during ischemia/reperfusion injury. Circ Res (2002) 1.18
Retracted STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage. J Cell Sci (2005) 1.17
BAG-1: a multi-functional pro-survival molecule. Int J Biochem Cell Biol (2005) 1.14
Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human beta(2)-glycoprotein I: mutation studies including residues R39 to R43. Arthritis Rheum (2007) 1.12
Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression. Neurobiol Dis (2007) 1.11
Bimoclomol, a heat shock protein co-inducer, acts by the prolonged activation of heat shock factor-1. Biochem Biophys Res Commun (2003) 1.10
HSP27 but not HSP70 has a potent protective effect against alpha-synuclein-induced cell death in mammalian neuronal cells. J Neurochem (2004) 1.09
Activation of protein kinase B/Akt by urocortin is essential for its ability to protect cardiac cells against hypoxia/reoxygenation-induced cell death. J Mol Cell Cardiol (2002) 1.09
Targeted disruption of the protein kinase C epsilon gene abolishes the infarct size reduction that follows ischaemic preconditioning of isolated buffer-perfused mouse hearts. Cardiovasc Res (2002) 1.09
Regulation of stress-induced intracellular sorting and chaperone function of Hsp27 (HspB1) in mammalian cells. Biochem J (2007) 1.07
Molecular basis of Parkinson's disease. Neuroreport (2009) 1.06
Neuroprotective effects of HSP70 overexpression after cerebral ischaemia--an MRI study. Exp Neurol (2005) 1.05
Hsp27 overexpression in the R6/2 mouse model of Huntington's disease: chronic neurodegeneration does not induce Hsp27 activation. Hum Mol Genet (2007) 1.03
IL-6 induces PI 3-kinase and nitric oxide-dependent protection and preserves mitochondrial function in cardiomyocytes. Cardiovasc Res (2005) 1.02
STAT3 deletion sensitizes cells to oxidative stress. Biochem Biophys Res Commun (2009) 1.02
Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to determine cell fate. J Biol Chem (2004) 1.02
Hsp27 and Hsp70 administered in combination have a potent protective effect against FALS-associated SOD1-mutant-induced cell death in mammalian neuronal cells. Brain Res Mol Brain Res (2004) 1.02
The carboxyl-terminal activation domain of the STAT-1 transcription factor enhances ischemia/reperfusion-induced apoptosis in cardiac myocytes. FASEB J (2002) 1.01
ERK and the F-box protein betaTRCP target STAT1 for degradation. J Biol Chem (2008) 1.00
Urocortin protects the heart from reperfusion injury via upregulation of p42/p44 MAPK signaling pathway. Am J Physiol Heart Circ Physiol (2002) 1.00
Stressful preconditioning and HSP70 overexpression attenuate proteotoxicity of cellular ATP depletion. Am J Physiol Cell Physiol (2002) 1.00
STAT3 modulates the DNA damage response pathway. Int J Exp Pathol (2010) 1.00
The effects of Brn-3a on neuronal differentiation and apoptosis are differentially modulated by EWS and its oncogenic derivative EWS/Fli-1. Oncogene (2004) 0.99
STAT1 interacts directly with cyclin D1/Cdk4 and mediates cell cycle arrest. Cell Cycle (2010) 0.99
Neuroprotective effects of virally delivered HSPs in experimental stroke. J Cereb Blood Flow Metab (2006) 0.98
Brn-3b enhances the pro-apoptotic effects of p53 but not its induction of cell cycle arrest by cooperating in trans-activation of bax expression. Nucleic Acids Res (2006) 0.97
Protective effect of post-ischaemic viral delivery of heat shock proteins in vivo. J Cereb Blood Flow Metab (2008) 0.96
Urocortin promotes hemodynamic and bioenergetic recovery and improves cell survival in the isolated rat heart exposed to ischemia/reperfusion. J Am Coll Cardiol (2002) 0.95
BAG-1 proteins protect cardiac myocytes from simulated ischemia/reperfusion-induced apoptosis via an alternate mechanism of cell survival independent of the proteasome. J Biol Chem (2004) 0.94
Free radical scavenging inhibits STAT phosphorylation following in vivo ischemia/reperfusion injury. FASEB J (2006) 0.94
Cardiotrophin-1 (CT-1) can protect the adult heart from injury when added both prior to ischaemia and at reperfusion. Cardiovasc Res (2002) 0.93
Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival. Hum Mol Genet (2003) 0.93
How do antiphospholipid antibodies bind beta2-glycoprotein I? Arthritis Rheum (2003) 0.92
Overexpression of heat shock protein 27 reduces cortical damage after cerebral ischemia. J Cereb Blood Flow Metab (2009) 0.92
Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition. Neurobiol Dis (2005) 0.92
New targets of urocortin-mediated cardioprotection. J Mol Endocrinol (2010) 0.91
Transcriptional modulation of heat-shock protein gene expression. Biochem Res Int (2010) 0.91
The transcriptional coactivator p300 plays a critical role in the hypertrophic and protective pathways induced by phenylephrine in cardiac cells but is specific to the hypertrophic effect of urocortin. Chembiochem (2005) 0.91
CREB-binding protein activation by presenilin 1 but not by its M146L mutant. Neuroreport (2006) 0.91
Expression of the Brn-3b transcription factor correlates with expression of HSP-27 in breast cancer biopsies and is required for maximal activation of the HSP-27 promoter. Cancer Res (2005) 0.90
Myocyte enhancer factor 2 and chorion factor 2 collaborate in activation of the myogenic program in Drosophila. Mol Cell Biol (2007) 0.90
A novel expression system of domain I of human beta2 glycoprotein I in Escherichia coli. BMC Biotechnol (2006) 0.90
The selective PPARgamma antagonist GW9662 reverses the protection of LPS in a model of renal ischemia-reperfusion. Kidney Int (2005) 0.90
Relative importance of different human aPL derived heavy and light chains in the binding of aPL to cardiolipin. Mol Immunol (2003) 0.90
The cardioprotective effect of urocortin during ischaemia/reperfusion involves the prevention of mitochondrial damage. Biochem Biophys Res Commun (2004) 0.89
Targeting Brn-3b in breast cancer therapy. Expert Opin Ther Targets (2006) 0.89
Arginine mutation alters binding of a human monoclonal antibody to antigens linked to systemic lupus erythematosus and the antiphospholipid syndrome. Arthritis Rheum (2007) 0.88
STAT1 regulates p73-mediated Bax gene expression. FEBS Lett (2007) 0.88
HSP27 protects AML cells against VP-16-induced apoptosis through modulation of p38 and c-Jun. Exp Hematol (2005) 0.87
The Brn-3b transcription factor regulates the growth, behavior, and invasiveness of human neuroblastoma cells in vitro and in vivo. J Biol Chem (2004) 0.87
Heat shock protein 27 delivered via a herpes simplex virus vector can protect neurons of the hippocampus against kainic-acid-induced cell loss. Brain Res Mol Brain Res (2003) 0.87
Hsf1-mediated stress response can transiently enhance cellular radioresistance. Radiat Res (2006) 0.86
Induction of parkin expression in the presence of oxidative stress. Eur J Neurosci (2006) 0.86
p73-mediated transcriptional activity is negatively regulated by polo-like kinase 1. Cell Cycle (2008) 0.86
Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signaling pathways. J Immunol (2010) 0.86
p300 activation by Presenilin 1 but not by its M146L mutant. Neurosci Lett (2007) 0.86
Analysis of skeletal muscle development in Drosophila. Methods Mol Biol (2012) 0.86
Anti-cardiolipin/beta-2 glycoprotein activities co-exist on human anti-DNA antibody light chains. Mol Immunol (2003) 0.84
A systematic analysis of sequences of human antiphospholipid and anti-beta2-glycoprotein I antibodies: the importance of somatic mutations and certain sequence motifs. Semin Arthritis Rheum (2003) 0.84
Nurr1 transcriptionally regulates the expression of alpha-synuclein. Neuroreport (2008) 0.84
Regulation of Brn-3a N-terminal transcriptional activity by MEK1/2-ERK1/2 signalling in neural differentiation. Brain Res (2008) 0.83
Retracted Antiapoptotic activity of the free caspase recruitment domain of procaspase-9: a novel endogenous rescue pathway in cell death. J Biol Chem (2002) 0.83
Hypertrophic effects of urocortin homologous peptides are mediated via activation of the Akt pathway. Biochem Biophys Res Commun (2005) 0.83
Cloning, characterization, and heat stress-induced redistribution of a protein homologous to human hsp27 in the zebrafish Danio rerio. Exp Cell Res (2005) 0.83
Estrogen and non-genomic upregulation of voltage-gated Na(+) channel activity in MDA-MB-231 human breast cancer cells: role in adhesion. J Cell Physiol (2010) 0.83
Stable expression of a recombinant human antinucleosome antibody to investigate relationships between antibody sequence, binding properties, and pathogenicity. Arthritis Res Ther (2005) 0.83
Hsp27 is persistently expressed in zebrafish skeletal and cardiac muscle tissues but dispensable for their morphogenesis. Cell Stress Chaperones (2009) 0.82
The Brn-3b POU family transcription factor represses plakoglobin gene expression in human breast cancer cells. Int J Cancer (2006) 0.82
Cardiotrophin-1 and urocortin cause protection by the same pathway and hypertrophy via distinct pathways in cardiac myocytes. Cytokine (2002) 0.82
Somatic mutations to arginine residues affect the binding of human monoclonal antibodies to DNA, histones, SmD and Ro antigen. Mol Immunol (2004) 0.82
Cell-specific regulation of the pro-survival Brn-3b transcription factor by microRNAs. Mol Cell Neurosci (2010) 0.82
Regulation of myocardial interleukin-6 expression by p53 and STAT1. J Interferon Cytokine Res (2013) 0.81
Post-transcriptional regulation of the Brn-3b transcription factor in differentiating neuroblastoma cells. FEBS Lett (2007) 0.81
Distinct serine residues in CBP and p300 are necessary for their activation by phenylephrine. Int J Biochem Cell Biol (2004) 0.81
Modulation of cell death by alpha-synuclein is stimulus-dependent in mammalian cells. Neurosci Lett (2003) 0.80
The pro-oncoprotein EWS (Ewing's Sarcoma protein) interacts with the Brn-3a POU transcription factor and inhibits its ability to activate transcription. Cancer Biol Ther (2002) 0.80
Measurement of Brn-3a levels in Pap smears provides a novel diagnostic marker for the detection of cervical neoplasia. Gynecol Oncol (2003) 0.80
Identification and characterization of the promoter region of the Nav1.7 voltage-gated sodium channel gene (SCN9A). Mol Cell Neurosci (2007) 0.80