Published in J Biol Chem on April 26, 2004
Proteasome subunit Rpn13 is a novel ubiquitin receptor. Nature (2008) 4.76
Complete subunit architecture of the proteasome regulatory particle. Nature (2012) 4.41
A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. Mol Cell (2008) 2.96
Molecular mechanisms of proteasome assembly. Nat Rev Mol Cell Biol (2009) 2.82
Structural organization of the 19S proteasome lid: insights from MS of intact complexes. PLoS Biol (2006) 2.56
hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37. EMBO J (2006) 2.35
Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome. EMBO J (2009) 1.93
Conformational switching of the 26S proteasome enables substrate degradation. Nat Struct Mol Biol (2013) 1.90
The Princeton Protein Orthology Database (P-POD): a comparative genomics analysis tool for biologists. PLoS One (2007) 1.83
Assembly, structure, and function of the 26S proteasome. Trends Cell Biol (2010) 1.61
The assembly pathway of the 19S regulatory particle of the yeast 26S proteasome. Mol Biol Cell (2006) 1.46
Glycine-alanine repeats impair proper substrate unfolding by the proteasome. EMBO J (2006) 1.34
Sem1 is a functional component of the nuclear pore complex-associated messenger RNA export machinery. J Cell Biol (2009) 1.25
Identification and characterization of a Drosophila proteasome regulatory network. Mol Cell Biol (2005) 1.18
Some assembly required: dedicated chaperones in eukaryotic proteasome biogenesis. Biol Chem (2008) 1.16
Dss1 interaction with Brh2 as a regulatory mechanism for recombinational repair. Mol Cell Biol (2007) 1.11
Functional characterization of tissue-specific enhancers in the DLX5/6 locus. Hum Mol Genet (2012) 1.11
Proteasomal ATPase-associated factor 1 negatively regulates proteasome activity by interacting with proteasomal ATPases. Mol Cell Biol (2005) 1.09
Thioredoxin Txnl1/TRP32 is a redox-active cofactor of the 26 S proteasome. J Biol Chem (2009) 1.08
The homologous recombination system of Ustilago maydis. Fungal Genet Biol (2008) 1.07
A high-throughput screen to identify enhancers of ADAR-mediated RNA-editing. RNA Biol (2013) 1.04
Dependence of proteasome processing rate on substrate unfolding. J Biol Chem (2011) 1.02
Dss1 is a 26S proteasome ubiquitin receptor. Mol Cell (2014) 0.93
Fission yeast Dss1 associates with the proteasome and is required for efficient ubiquitin-dependent proteolysis. Biochem J (2006) 0.93
Functional assays for analysis of variants of uncertain significance in BRCA2. Hum Mutat (2013) 0.92
Functions of the 19S complex in proteasomal degradation. Trends Biochem Sci (2013) 0.90
The ubiquitin-proteasome system in cancer, a major player in DNA repair. Part 1: post-translational regulation. J Cell Mol Med (2009) 0.90
Dss1 regulates interaction of Brh2 with DNA. Biochemistry (2009) 0.90
Designed proteins to modulate cellular networks. ACS Chem Biol (2010) 0.89
The intrinsically disordered Sem1 protein functions as a molecular tether during proteasome lid biogenesis. Mol Cell (2014) 0.89
BRCA2 suppresses cell proliferation via stabilizing MAGE-D1. Cancer Res (2005) 0.87
Disordered proteinaceous machines. Chem Rev (2014) 0.86
Direct ubiquitin independent recognition and degradation of a folded protein by the eukaryotic proteasomes-origin of intrinsic degradation signals. PLoS One (2012) 0.83
Base-CP proteasome can serve as a platform for stepwise lid formation. Biosci Rep (2015) 0.83
Sem1: a versatile "molecular glue"? Nucleus (2011) 0.81
C. elegans dss-1 is functionally conserved and required for oogenesis and larval growth. BMC Dev Biol (2008) 0.81
DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells. Protein Cell (2014) 0.80
BRCA2: one small step for DNA repair, one giant protein purified. Yale J Biol Med (2013) 0.79
The 26S proteasome drives trinucleotide repeat expansions. Nucleic Acids Res (2013) 0.78
A Rapid and Versatile Method for Generating Proteins with Defined Ubiquitin Chains. Biochemistry (2016) 0.78
The spectrum of spontaneous mutations caused by deficiency in proteasome maturase Ump1 in Saccharomyces cerevisiae. Curr Genet (2007) 0.77
The over-expression of the β2 catalytic subunit of the proteasome decreases homologous recombination and impairs DNA double-strand break repair in human cells. J Biomed Biotechnol (2011) 0.76
DSSylation, a novel guide for protein degradation? Protein Cell (2014) 0.75
A Novel Frizzled-Based Screening Tool Identifies Genetic Modifiers of Planar Cell Polarity in Drosophila Wings. G3 (Bethesda) (2016) 0.75
High-resolution cryo-EM structure of the proteasome in complex with ADP-AlFx. Cell Res (2017) 0.75
Ubiquitinated proteins promote the association of proteasomes with the deubiquitinating enzyme Usp14 and the ubiquitin ligase Ube3c. Proc Natl Acad Sci U S A (2017) 0.75
Proteasome Structure and Assembly. J Mol Biol (2017) 0.75
Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation. Nat Cell Biol (2009) 6.62
SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex. Nature (2011) 3.77
Cellular factors required for Lassa virus budding. J Virol (2006) 2.02
Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domain. EMBO Rep (2003) 2.01
Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome. EMBO J (2009) 1.93
Ubiquitin-like proteins and Rpn10 play cooperative roles in ubiquitin-dependent proteolysis. Biochem Biophys Res Commun (2002) 1.57
Identification of ubiquitin-like protein-binding subunits of the 26S proteasome. Biochem Biophys Res Commun (2002) 1.53
BAG-6 is essential for selective elimination of defective proteasomal substrates. J Cell Biol (2010) 1.46
The assembly pathway of the 19S regulatory particle of the yeast 26S proteasome. Mol Biol Cell (2006) 1.46
Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopy. Proc Natl Acad Sci U S A (2012) 1.42
Direct interactions between NEDD8 and ubiquitin E2 conjugating enzymes upregulate cullin-based E3 ligase activity. Nat Struct Mol Biol (2007) 1.38
Mitotic exit network controls the localization of Cdc14 to the spindle pole body in Saccharomyces cerevisiae. Curr Biol (2002) 1.37
Tom1, a VHS domain-containing protein, interacts with tollip, ubiquitin, and clathrin. J Biol Chem (2003) 1.37
Functional analysis of Rpn6p, a lid component of the 26 S proteasome, using temperature-sensitive rpn6 mutants of the yeast Saccharomyces cerevisiae. J Biol Chem (2004) 1.32
Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense. Proc Natl Acad Sci U S A (2010) 1.31
c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130. Mol Cell Biol (2008) 1.31
Yeast Whi2 and Psr1-phosphatase form a complex and regulate STRE-mediated gene expression. Genes Cells (2002) 1.20
The catalytic activity of Ubp6 enhances maturation of the proteasomal regulatory particle. Mol Cell (2011) 1.17
Ras recruits mitotic exit regulator Lte1 to the bud cortex in budding yeast. J Cell Biol (2003) 1.16
PIAS3 induces SUMO-1 modification and transcriptional repression of IRF-1. FEBS Lett (2002) 1.15
Definitive evidence for Ufd2-catalyzed elongation of the ubiquitin chain through Lys48 linkage. Biochem Biophys Res Commun (2004) 1.12
Dissection of the assembly pathway of the proteasome lid in Saccharomyces cerevisiae. Biochem Biophys Res Commun (2010) 1.10
Identification and Herc5-mediated ISGylation of novel target proteins. Biochem Biophys Res Commun (2006) 1.10
Production of antipolyubiquitin monoclonal antibodies and their use for characterization and isolation of polyubiquitinated proteins. Methods Enzymol (2005) 1.10
N-Terminal modifications of the 19S regulatory particle subunits of the yeast proteasome. Arch Biochem Biophys (2003) 1.09
Antiproliferative proteins of the BTG/Tob family are degraded by the ubiquitin-proteasome system. Eur J Biochem (2002) 1.08
Link between the ubiquitin conjugation system and the ISG15 conjugation system: ISG15 conjugation to the UbcH6 ubiquitin E2 enzyme. J Biochem (2005) 1.08
Shs1 plays separable roles in septin organization and cytokinesis in Saccharomyces cerevisiae. Genetics (2007) 1.08
Structural basis for specific recognition of Rpt1p, an ATPase subunit of 26 S proteasome, by proteasome-dedicated chaperone Hsm3p. J Biol Chem (2012) 1.08
ISG15 modification of Ubc13 suppresses its ubiquitin-conjugating activity. Biochem Biophys Res Commun (2005) 1.06
Budding yeast Cdc5 phosphorylates Net1 and assists Cdc14 release from the nucleolus. Biochem Biophys Res Commun (2002) 1.06
Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN. Genes Cells (2014) 1.06
The parallel reaction monitoring method contributes to a highly sensitive polyubiquitin chain quantification. Biochem Biophys Res Commun (2013) 1.05
Proteasomal degradation resolves competition between cell polarization and cellular wound healing. Cell (2012) 1.05
Ybr267w is a new cytoplasmic protein belonging to the mitotic signaling network of Saccharomyces cerevisiae. Cell Struct Funct (2004) 1.05
Proteasomal ubiquitin receptor RPN-10 controls sex determination in Caenorhabditis elegans. Mol Biol Cell (2006) 1.04
Forchlorfenuron, a phenylurea cytokinin, disturbs septin organization in Saccharomyces cerevisiae. Genes Genet Syst (2004) 1.04
Extracellular ubiquitination and proteasome-mediated degradation of the ascidian sperm receptor. Proc Natl Acad Sci U S A (2002) 1.03
Phosphorelay-regulated degradation of the yeast Ssk1p response regulator by the ubiquitin-proteasome system. Mol Cell Biol (2003) 1.03
Rpn7 Is required for the structural integrity of the 26 S proteasome of Saccharomyces cerevisiae. J Biol Chem (2004) 1.03
Unique proteasome subunit Xrpn10c is a specific receptor for the antiapoptotic ubiquitin-like protein Scythe. FEBS J (2005) 1.03
Regulation of the interaction between glycogen synthase kinase 3 and the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen. J Virol (2005) 1.01
The proteasome: molecular machinery and pathophysiological roles. Biol Chem (2012) 1.00
Mammalian 26S proteasomes remain intact during protein degradation. Cell (2008) 1.00
Intracellularly inducible, ubiquitin hydrolase-insensitive tandem ubiquitins inhibit the 26S proteasome activity and cell division. Genes Genet Syst (2004) 0.99
Physical and functional interactions between STAT3 and Kaposi's sarcoma-associated herpesvirus-encoded LANA. FEBS Lett (2005) 0.98
Leucettamol A: a new inhibitor of Ubc13-Uev1A interaction isolated from a marine sponge, Leucetta aff. microrhaphis. Bioorg Med Chem Lett (2008) 0.97
Human T-cell leukemia virus type 1 HBZ protein bypasses the targeting function of ubiquitination. J Biol Chem (2008) 0.94
OMA-1 is a P granules-associated protein that is required for germline specification in Caenorhabditis elegans embryos. Genes Cells (2006) 0.92
Tom1 (target of Myb 1) is a novel negative regulator of interleukin-1- and tumor necrosis factor-induced signaling pathways. Biol Pharm Bull (2004) 0.92
Yeast Pho85 kinase is required for proper gene expression during the diauxic shift. Yeast (2004) 0.92
Regulation of the nuclear factor (NF)-kappaB pathway by ISGylation. Biol Pharm Bull (2008) 0.91
A defect of Kap104 alleviates the requirement of mitotic exit network gene functions in Saccharomyces cerevisiae. Genetics (2002) 0.91
Scythe regulates apoptosis through modulating ubiquitin-mediated proteolysis of the Xenopus elongation factor XEF1AO. Biochem J (2007) 0.90
Negative regulation of protein phosphatase 2Cbeta by ISG15 conjugation. FEBS Lett (2006) 0.90
Epidemiology of Epstein-Barr virus, cytomegalovirus, and Kaposi's sarcoma-associated herpesvirus infections in peripheral blood leukocytes revealed by a multiplex PCR assay. J Med Virol (2006) 0.89
Crystal structure of yeast rpn14, a chaperone of the 19 S regulatory particle of the proteasome. J Biol Chem (2010) 0.89
Spongiacidin C, a pyrrole alkaloid from the marine sponge Stylissa massa, functions as a USP7 inhibitor. Bioorg Med Chem Lett (2013) 0.88
Natural products inhibiting the ubiquitin-proteasome proteolytic pathway, a target for drug development. Curr Med Chem (2006) 0.87
Hexylitaconic acid: a new inhibitor of p53-HDM2 interaction isolated from a marine-derived fungus, Arthrinium sp. Bioorg Med Chem Lett (2005) 0.86
Localization and characterization of γ-glutamyl cyclotransferase in cancer cells. Mol Med Rep (2011) 0.85
Inhibition of the ubiquitin-proteasome system by natural products for cancer therapy. Planta Med (2010) 0.85
Involvement of polyubiquitin chains via specific chain linkages in stress response in mammalian cells. Biol Pharm Bull (2005) 0.85
Targeting the proteasome pathway. Expert Opin Ther Targets (2009) 0.84
Extracellular ubiquitin system implicated in fertilization of the ascidian, Halocynthia roretzi: isolation and characterization. Dev Biol (2003) 0.83
cDNA microarray analyses reveal candidate marker genes for the detection of ascidian disease in Korea. Zoolog Sci (2007) 0.82
Himeic acid A: a new ubiquitin-activating enzyme inhibitor isolated from a marine-derived fungus, Aspergillus sp. Bioorg Med Chem Lett (2005) 0.82
Detection and analysis of protein ISGylation. Methods Mol Biol (2008) 0.82
Transcriptional repression by the Pho4 transcription factor controls the timing of SNZ1 expression. Eukaryot Cell (2008) 0.82
The 26S proteasome Rpn10 gene encoding splicing isoforms: evolutional conservation of the genomic organization in vertebrates. Biol Chem (2002) 0.81
Girolline, an antitumor compound isolated from a sponge, induces G2/M cell cycle arrest and accumulation of polyubiquitinated p53. Biol Pharm Bull (2004) 0.81
Molecular piracy: manipulation of the ubiquitin system by Kaposi's sarcoma-associated herpesvirus. Rev Med Virol (2007) 0.81
Pho85 kinase, a cyclin-dependent kinase, regulates nuclear accumulation of the Rim101 transcription factor in the stress response of Saccharomyces cerevisiae. Eukaryot Cell (2010) 0.81
Regulation of HTLV-1 Gag budding by Vps4A, Vps4B, and AIP1/Alix. Virol J (2007) 0.80
Therapeutic effect of camostat mesilate on Duchenne muscular dystrophy in mdx mice. Biol Pharm Bull (2003) 0.80
Cell-cycle dependent dynamic change of 26S proteasome distribution in tobacco BY-2 cells. Plant Cell Physiol (2002) 0.80
Cell biology: two hands for degradation. Nature (2008) 0.80
Aaptamine, an alkaloid from the sponge Aaptos suberitoides, functions as a proteasome inhibitor. Bioorg Med Chem Lett (2010) 0.80
Self/nonself recognition in ascidian fertilization: vitelline coat protein HrVC70 is a candidate allorecognition molecule. Proc Natl Acad Sci U S A (2004) 0.79
Regulation of NF-kappaB/Rel by IkappaB is essential for ascidian notochord formation. Dev Biol (2005) 0.79
Hyrtioreticulins A-E, indole alkaloids inhibiting the ubiquitin-activating enzyme, from the marine sponge Hyrtios reticulatus. Bioorg Med Chem (2012) 0.79
Highly polymorphic vitelline-coat protein HaVC80 from the ascidian, Halocynthia aurantium: structural analysis and involvement in self/nonself recognition during fertilization. Dev Biol (2005) 0.79
Solution structure of ascidian trypsin inhibitor determined by nuclear magnetic resonance spectroscopy. Biochemistry (2002) 0.79
Differential display analysis reveals the expression of glutathione S-transferase omega and novel genes through an ITAM-containing receptor in ascidian immunocytes. Immunogenetics (2005) 0.78
Rsp5-Bul1/2 complex is necessary for the HSE-mediated gene expression in budding yeast. Biochem Biophys Res Commun (2003) 0.78
Small ubiquitin-related modifier is secreted and shows cytokine-like activity. Biol Pharm Bull (2008) 0.78