Published in J Biol Chem on April 29, 2004
The developmental cell biology of Trypanosoma brucei. J Cell Sci (2005) 1.84
The Trypanosoma brucei flagellum: moving parasites in new directions. Annu Rev Microbiol (2009) 1.66
Trypanosoma brucei homologous recombination is dependent on substrate length and homology, though displays a differential dependence on mismatch repair as substrate length decreases. Nucleic Acids Res (2007) 1.29
Trypanosome telomeres are protected by a homologue of mammalian TRF2. Mol Cell Biol (2005) 1.19
CRE recombinase-based positive-negative selection systems for genetic manipulation in Trypanosoma brucei. Mol Biochem Parasitol (2007) 1.05
MCM-BP is required for repression of life-cycle specific genes transcribed by RNA polymerase I in the mammalian infectious form of Trypanosoma brucei. PLoS One (2013) 1.03
The lipid-linked oligosaccharide donor specificities of Trypanosoma brucei oligosaccharyltransferases. Glycobiology (2012) 0.90
Approaches for functional analysis of flagellar proteins in African trypanosomes. Methods Cell Biol (2009) 0.88
Antiparasitic chemotherapy: from genomes to mechanisms. Annu Rev Pharmacol Toxicol (2013) 0.88
Genetic dissection of drug resistance in trypanosomes. Parasitology (2013) 0.86
A transposon toolkit for gene transfer and mutagenesis in protozoan parasites. Genetica (2009) 0.85
Identification and functional characterization of a highly divergent N-acetylglucosaminyltransferase I (TbGnTI) in Trypanosoma brucei. J Biol Chem (2014) 0.82
Affinity is an important determinant of the anti-trypanosome activity of nanobodies. PLoS Negl Trop Dis (2012) 0.79
A novel strategy to identify the location of necessary and sufficient cis-acting regulatory mRNA elements in trypanosomes. RNA (2005) 0.79
New insights into the molecular mechanisms of mitosis and cytokinesis in trypanosomes. Int Rev Cell Mol Biol (2014) 0.77
Characterization of an African trypanosome mutant refractory to lectin-induced death. Biochem Biophys Rep (2015) 0.75
RFT1 affects GPI anchor glycosylation. J Biol Chem (2016) 0.75
A systematic survey of loss-of-function variants in human protein-coding genes. Science (2012) 12.25
Volumetric modulated arc therapy for delivery of prostate radiotherapy: comparison with intensity-modulated radiotherapy and three-dimensional conformal radiotherapy. Int J Radiat Oncol Biol Phys (2008) 3.65
Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei. Genes Dev (2009) 3.62
Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites. Nucleic Acids Res (2010) 2.38
Telomeric expression sites are highly conserved in Trypanosoma brucei. PLoS One (2008) 2.22
Developmental progression to infectivity in Trypanosoma brucei triggered by an RNA-binding protein. Science (2012) 1.94
A unified phylogeny-based nomenclature for histone variants. Epigenetics Chromatin (2012) 1.82
A histone methyltransferase modulates antigenic variation in African trypanosomes. PLoS Biol (2008) 1.72
Selective di- or trimethylation of histone H3 lysine 76 by two DOT1 homologs is important for cell cycle regulation in Trypanosoma brucei. Mol Cell (2006) 1.70
MicroRNAs associated with metastatic prostate cancer. PLoS One (2011) 1.66
A family of ductile intermetallic compounds. Nat Mater (2003) 1.66
High fidelity patient-derived xenografts for accelerating prostate cancer discovery and drug development. Cancer Res (2013) 1.58
Nucleosomes are depleted at the VSG expression site transcribed by RNA polymerase I in African trypanosomes. Eukaryot Cell (2009) 1.52
A variant histone H3 is enriched at telomeres in Trypanosoma brucei. J Cell Sci (2004) 1.45
A yeast-endonuclease-generated DNA break induces antigenic switching in Trypanosoma brucei. Nature (2009) 1.44
Systematic study of sequence motifs for RNA trans splicing in Trypanosoma brucei. Mol Cell Biol (2005) 1.36
Trypanosomal TBP functions with the multisubunit transcription factor tSNAP to direct spliced-leader RNA gene expression. Mol Cell Biol (2005) 1.35
Surface sialic acids taken from the host allow trypanosome survival in tsetse fly vectors. J Exp Med (2004) 1.31
The suppression of galactose metabolism in procylic form Trypanosoma brucei causes cessation of cell growth and alters procyclin glycoprotein structure and copy number. J Biol Chem (2005) 1.30
Unusual histone modifications in Trypanosoma brucei. FEBS Lett (2006) 1.28
Histone modifications in Trypanosoma brucei. Mol Biochem Parasitol (2007) 1.27
Histone H2AZ dimerizes with a novel variant H2B and is enriched at repetitive DNA in Trypanosoma brucei. J Cell Sci (2005) 1.25
A computational investigation of kinetoplastid trans-splicing. Genome Biol (2005) 1.23
Preclinical safety evaluation of AAV2-sFLT01- a gene therapy for age-related macular degeneration. Mol Ther (2010) 1.22
The architecture of variant surface glycoprotein gene expression sites in Trypanosoma brucei. Mol Biochem Parasitol (2002) 1.20
Epigenetic regulation in African trypanosomes: a new kid on the block. Nat Rev Microbiol (2009) 1.20
Multifunctional class I transcription in Trypanosoma brucei depends on a novel protein complex. EMBO J (2007) 1.20
Alba-domain proteins of Trypanosoma brucei are cytoplasmic RNA-binding proteins that interact with the translation machinery. PLoS One (2011) 1.19
Trypanosome telomeres are protected by a homologue of mammalian TRF2. Mol Cell Biol (2005) 1.19
Flying tryps: survival and maturation of trypanosomes in tsetse flies. Trends Parasitol (2013) 1.19
Differential trypanosome surface coat regulation by a CCCH protein that co-associates with procyclin mRNA cis-elements. PLoS Pathog (2009) 1.17
GPI-anchored proteins and free GPI glycolipids of procyclic form Trypanosoma brucei are nonessential for growth, are required for colonization of the tsetse fly, and are not the only components of the surface coat. Mol Biol Cell (2006) 1.16
Two essential MYST-family proteins display distinct roles in histone H4K10 acetylation and telomeric silencing in trypanosomes. Mol Microbiol (2008) 1.15
Parasitic exploitation as an engine of diversity. Biol Rev Camb Philos Soc (2003) 1.14
Deletion of the TbALG3 gene demonstrates site-specific N-glycosylation and N-glycan processing in Trypanosoma brucei. Glycobiology (2008) 1.14
Telomere structure and function in trypanosomes: a proposal. Nat Rev Microbiol (2006) 1.13
TOPO3alpha influences antigenic variation by monitoring expression-site-associated VSG switching in Trypanosoma brucei. PLoS Pathog (2010) 1.11
Analysis of the Trypanosoma brucei cell cycle by quantitative DAPI imaging. Mol Biochem Parasitol (2008) 1.11
An adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U deamination of DNA. Proc Natl Acad Sci U S A (2007) 1.10
Gene expression in Trypanosoma brucei: lessons from high-throughput RNA sequencing. Trends Parasitol (2011) 1.10
Cholesterol import fails to prevent catalyst-based inhibition of ergosterol synthesis and cell proliferation of Trypanosoma brucei. J Lipid Res (2006) 1.08
Two thymidine hydroxylases differentially regulate the formation of glucosylated DNA at regions flanking polymerase II polycistronic transcription units throughout the genome of Trypanosoma brucei. Nucleic Acids Res (2010) 1.08
Acetylation of histone H4K4 is cell cycle regulated and mediated by HAT3 in Trypanosoma brucei. Mol Microbiol (2007) 1.08
Impact of neoadjuvant androgen ablation and other factors on late toxicity after external beam prostate radiotherapy. Int J Radiat Oncol Biol Phys (2004) 1.05
CRE recombinase-based positive-negative selection systems for genetic manipulation in Trypanosoma brucei. Mol Biochem Parasitol (2007) 1.05
Mutational analysis of the variant surface glycoprotein GPI-anchor signal sequence in Trypanosoma brucei. J Cell Sci (2002) 1.05
Telomere length regulation and transcriptional silencing in KU80-deficient Trypanosoma brucei. Nucleic Acids Res (2004) 1.04
MCM-BP is required for repression of life-cycle specific genes transcribed by RNA polymerase I in the mammalian infectious form of Trypanosoma brucei. PLoS One (2013) 1.03
Trypanosoma congolense procyclins: unmasking cryptic major surface glycoproteins in procyclic forms. Eukaryot Cell (2006) 1.03
3D needle-tissue interaction simulation for prostate brachytherapy. Med Image Comput Comput Assist Interv (2005) 1.03
Use of computed tomography imaging for quantifying coarse roots, rhizomes, peat, and particle densities in marsh soils. Ecol Appl (2011) 1.02
Glycoprotein biosynthesis in a eukaryote lacking the membrane protein Rft1. J Biol Chem (2013) 1.02
Structural features affecting variant surface glycoprotein expression in Trypanosoma brucei. Mol Biochem Parasitol (2003) 1.00
Histone H3 trimethylated at lysine 4 is enriched at probable transcription start sites in Trypanosoma brucei. Mol Biochem Parasitol (2010) 1.00
The essential polysome-associated RNA-binding protein RBP42 targets mRNAs involved in Trypanosoma brucei energy metabolism. RNA (2012) 0.99
Trypanosoma brucei Orc1 is essential for nuclear DNA replication and affects both VSG silencing and VSG switching. Mol Microbiol (2012) 0.98
Telomere length affects the frequency and mechanism of antigenic variation in Trypanosoma brucei. PLoS Pathog (2012) 0.98
Trypanosoma brucei expression-site-associated-gene-8 protein interacts with a Pumilio family protein. Mol Biochem Parasitol (2002) 0.94
Identification of Trypanosoma brucei RMI1/BLAP75 homologue and its roles in antigenic variation. PLoS One (2011) 0.94
Involved-nodal radiation therapy as a component of combination therapy for limited-stage Hodgkin's lymphoma: a question of field size. J Clin Oncol (2008) 0.94
Telomere structure and shortening in telomerase-deficient Trypanosoma brucei. Nucleic Acids Res (2005) 0.93
Telomerase-independent stabilization of short telomeres in Trypanosoma brucei. Mol Cell Biol (2006) 0.92
Trypanosome H2Bv replaces H2B in nucleosomes enriched for H3 K4 and K76 trimethylation. Biochem Biophys Res Commun (2008) 0.92
Trypanosoma brucei MRE11 is non-essential but influences growth, homologous recombination and DNA double-strand break repair. Mol Biochem Parasitol (2002) 0.92
Structural characterization of NETNES, a novel glycoconjugate in Trypanosoma cruzi epimastigotes. J Biol Chem (2005) 0.90
Microwave-accelerated iridium-catalyzed borylation of aromatic C-H bonds. Org Lett (2009) 0.90
Long-term outcomes for patients with limited stage follicular lymphoma: involved regional radiotherapy versus involved node radiotherapy. Cancer (2010) 0.89
Novel N-aryl and N-heteroaryl sulfamide synthesis via palladium cross coupling. Org Lett (2004) 0.89
Trichomonas vaginalis pathobiology new insights from the genome sequence. Adv Parasitol (2011) 0.88
Cleavage of trypanosome surface glycoproteins by alkaline trypsin-like enzyme(s) in the midgut of Glossina morsitans. Int J Parasitol (2003) 0.88
Consequences of telomere shortening at an active VSG expression site in telomerase-deficient Trypanosoma brucei. Eukaryot Cell (2006) 0.88
Targeted deletion of the gp72 gene decreases the infectivity of Trypanosoma cruzi for mice and insect vectors. J Parasitol (2002) 0.87
Trypanosoma brucei: TbRAB4 regulates membrane recycling and expression of surface proteins in procyclic forms. Exp Parasitol (2005) 0.87
Trypanosomes at the gates. Science (2005) 0.86
Developmental regulation and extracellular release of a VSG expression-site-associated gene product from Trypanosoma brucei bloodstream forms. J Cell Sci (2010) 0.86
Influenza treatment with neuraminidase inhibitors: cost-effectiveness and cost-utility in healthy adults in the United Kingdom. Eur J Health Econ (2005) 0.86
Computing intraoperative dosimetry for prostate brachytherapy using TRUS and fluoroscopy. Acad Radiol (2005) 0.85
Strategies to construct null and conditional null Trypanosoma brucei mutants using Cre-recombinase and loxP. Mol Biochem Parasitol (2013) 0.85
An organism-specific method to rank predicted coding regions in Trypanosoma brucei. Nucleic Acids Res (2003) 0.84
Pretreatment PSA velocity as a predictor of disease outcome following radical radiation therapy. Int J Radiat Oncol Biol Phys (2007) 0.83
Independent pathways can transduce the life-cycle differentiation signal in Trypanosoma brucei. PLoS Pathog (2013) 0.83
Epidemiologic modeling with FluSurge for pandemic (H1N1) 2009 outbreak, Queensland, Australia. Emerg Infect Dis (2011) 0.83
Assessment of behavioral mechanisms maintaining encopresis: Virginia Encopresis-Constipation Apperception Test. J Pediatr Psychol (2003) 0.83
Telomere length in Trypanosoma brucei. Exp Parasitol (2007) 0.81
Phosphorylation of GPEET procyclin is not necessary for survival of Trypanosoma brucei procyclic forms in culture and in the tsetse fly midgut. Mol Biochem Parasitol (2003) 0.79
Cutaneous Leishmaniasis and Conflict in Syria. Emerg Infect Dis (2016) 0.79
Cost-effectiveness of infliximab for the treatment of active and progressive psoriatic arthritis. Value Health (2011) 0.79
Trypanosoma brucei AMP-activated kinase subunit homologs influence surface molecule expression. Exp Parasitol (2009) 0.79
Analysis of Parkinson's disease brain-derived DNA for alpha-synuclein coding somatic mutations. Mov Disord (2014) 0.78
Urinary incontinence in prostate cancer patients treated with external beam radiotherapy. Radiother Oncol (2005) 0.78
Restoration of topoisomerase 2 function by complementation of defective monomers in Drosophila. Genetics (2012) 0.78
Lipid remodelling of glycosylphosphatidylinositol (GPI) glycoconjugates in procyclic-form trypanosomes: biosynthesis and processing of GPIs revisited. Biochem J (2010) 0.78
Opinion formation in evaluating the adjudicative competence and restorability of criminal defendants: a review of 8,000 evaluations. Behav Sci Law (2006) 0.77
Assessing deaf awareness training: knowledge and attitudes of recent genetic counseling graduates. J Genet Couns (2014) 0.77
Life in cells, hosts, and vectors: parasite evolution across scales. Infect Genet Evol (2012) 0.77
Fairness of financial penalties to improve control of Clostridium difficile. BMJ (2008) 0.77
The protease resistant surface (PRS) glycoconjugate from Trypanosoma congolense has an inositol-acylated glycosylphosphatidylinositol anchor, containing a significant proportion of myristate at the sn-2 position. Mol Biochem Parasitol (2010) 0.76
Rhodium-carbon bond energies in Tp'Rh(CNneopentyl)(CH2X)H: quantifying stabilization effects in M-C bonds. J Am Chem Soc (2013) 0.76
Drug discovery: Fat-free proteins kill parasites. Nature (2010) 0.75