Histone H2AZ dimerizes with a novel variant H2B and is enriched at repetitive DNA in Trypanosoma brucei.

PubWeight™: 1.25‹?› | Rank: Top 10%

🔗 View Article (PMID 16303849)

Published in J Cell Sci on November 22, 2005

Authors

Joanna E Lowell1, Franziska Kaiser, Christian J Janzen, George A M Cross

Author Affiliations

1: Laboratory of Molecular Parasitology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.

Articles citing this

Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei. Genes Dev (2009) 3.62

A unified phylogeny-based nomenclature for histone variants. Epigenetics Chromatin (2012) 1.82

Structure, dynamics, and evolution of centromeric nucleosomes. Proc Natl Acad Sci U S A (2007) 1.81

Nucleosomes are depleted at the VSG expression site transcribed by RNA polymerase I in African trypanosomes. Eukaryot Cell (2009) 1.52

Introducing histone modification in trypanosomes. Trends Parasitol (2007) 1.51

H2A.Z demarcates intergenic regions of the plasmodium falciparum epigenome that are dynamically marked by H3K9ac and H3K4me3. PLoS Pathog (2010) 1.47

Histone H2A variants in nucleosomes and chromatin: more or less stable? Nucleic Acids Res (2012) 1.33

Cell biology of the trypanosome genome. Microbiol Mol Biol Rev (2010) 1.27

Chromatin-mediated epigenetic regulation in the malaria parasite Plasmodium falciparum. Eukaryot Cell (2010) 1.26

Histone acetylation and methylation at sites initiating divergent polycistronic transcription in Trypanosoma cruzi. J Biol Chem (2008) 1.21

Epigenetic regulation in African trypanosomes: a new kid on the block. Nat Rev Microbiol (2009) 1.20

Gene expression in trypanosomatid parasites. J Biomed Biotechnol (2010) 1.18

Expression of P. falciparum var genes involves exchange of the histone variant H2A.Z at the promoter. PLoS Pathog (2011) 1.11

Toxoplasma H2A variants reveal novel insights into nucleosome composition and functions for this histone family. J Mol Biol (2009) 1.02

Histone H3 trimethylated at lysine 4 is enriched at probable transcription start sites in Trypanosoma brucei. Mol Biochem Parasitol (2010) 1.00

RNA polymerase transcription machinery in trypanosomes. Eukaryot Cell (2007) 0.98

Small interfering RNA-producing loci in the ancient parasitic eukaryote Trypanosoma brucei. BMC Genomics (2012) 0.96

Evolutionary cell biology of chromosome segregation: insights from trypanosomes. Open Biol (2013) 0.95

Chromatin modifications, epigenetics, and how protozoan parasites regulate their lives. Trends Parasitol (2012) 0.93

Trypanosome H2Bv replaces H2B in nucleosomes enriched for H3 K4 and K76 trimethylation. Biochem Biophys Res Commun (2008) 0.92

H2A.Z/H2B.Z double-variant nucleosomes inhabit the AT-rich promoter regions of the Plasmodium falciparum genome. Mol Microbiol (2013) 0.91

Toxoplasma histone acetylation remodelers as novel drug targets. Expert Rev Anti Infect Ther (2012) 0.88

Multi-faceted quantitative proteomics analysis of histone H2B isoforms and their modifications. Epigenetics Chromatin (2015) 0.81

Histone variant innovation in a rapidly evolving chordate lineage. BMC Evol Biol (2011) 0.79

FACT plays a major role in histone dynamics affecting VSG expression site control in Trypanosoma brucei. Mol Microbiol (2014) 0.76

Depletion of the RNA-binding protein RBP33 results in increased expression of silenced RNA polymerase II transcripts in Trypanosoma brucei. PLoS One (2014) 0.76

The epigenome of Trypanosoma brucei: a regulatory interface to an unconventional transcriptional machine. Biochim Biophys Acta (2014) 0.76

Quantitative proteomic analysis of replicative and non-replicative forms reveals important insights into chromatin biology of Trypanosoma cruzi. Mol Cell Proteomics (2016) 0.76

Identification of repressive and active epigenetic marks and nuclear bodies in Entamoeba histolytica. Parasit Vectors (2016) 0.76

Articles by these authors

Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei. Genes Dev (2009) 3.62

Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites. Nucleic Acids Res (2010) 2.38

Telomeric expression sites are highly conserved in Trypanosoma brucei. PLoS One (2008) 2.22

Developmental progression to infectivity in Trypanosoma brucei triggered by an RNA-binding protein. Science (2012) 1.94

A unified phylogeny-based nomenclature for histone variants. Epigenetics Chromatin (2012) 1.82

A histone methyltransferase modulates antigenic variation in African trypanosomes. PLoS Biol (2008) 1.72

Selective di- or trimethylation of histone H3 lysine 76 by two DOT1 homologs is important for cell cycle regulation in Trypanosoma brucei. Mol Cell (2006) 1.70

Nucleosomes are depleted at the VSG expression site transcribed by RNA polymerase I in African trypanosomes. Eukaryot Cell (2009) 1.52

A variant histone H3 is enriched at telomeres in Trypanosoma brucei. J Cell Sci (2004) 1.45

A yeast-endonuclease-generated DNA break induces antigenic switching in Trypanosoma brucei. Nature (2009) 1.44

Systematic study of sequence motifs for RNA trans splicing in Trypanosoma brucei. Mol Cell Biol (2005) 1.36

Trypanosomal TBP functions with the multisubunit transcription factor tSNAP to direct spliced-leader RNA gene expression. Mol Cell Biol (2005) 1.35

Unusual histone modifications in Trypanosoma brucei. FEBS Lett (2006) 1.28

Histone modifications in Trypanosoma brucei. Mol Biochem Parasitol (2007) 1.27

A computational investigation of kinetoplastid trans-splicing. Genome Biol (2005) 1.23

The architecture of variant surface glycoprotein gene expression sites in Trypanosoma brucei. Mol Biochem Parasitol (2002) 1.20

Epigenetic regulation in African trypanosomes: a new kid on the block. Nat Rev Microbiol (2009) 1.20

Multifunctional class I transcription in Trypanosoma brucei depends on a novel protein complex. EMBO J (2007) 1.20

Trypanosome telomeres are protected by a homologue of mammalian TRF2. Mol Cell Biol (2005) 1.19

Two essential MYST-family proteins display distinct roles in histone H4K10 acetylation and telomeric silencing in trypanosomes. Mol Microbiol (2008) 1.15

Comparative proteomics of two life cycle stages of stable isotope-labeled Trypanosoma brucei reveals novel components of the parasite's host adaptation machinery. Mol Cell Proteomics (2012) 1.14

Telomere structure and function in trypanosomes: a proposal. Nat Rev Microbiol (2006) 1.13

Analysis of the Trypanosoma brucei cell cycle by quantitative DAPI imaging. Mol Biochem Parasitol (2008) 1.11

TOPO3alpha influences antigenic variation by monitoring expression-site-associated VSG switching in Trypanosoma brucei. PLoS Pathog (2010) 1.11

An adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U deamination of DNA. Proc Natl Acad Sci U S A (2007) 1.10

Gene expression in Trypanosoma brucei: lessons from high-throughput RNA sequencing. Trends Parasitol (2011) 1.10

Cholesterol import fails to prevent catalyst-based inhibition of ergosterol synthesis and cell proliferation of Trypanosoma brucei. J Lipid Res (2006) 1.08

Acetylation of histone H4K4 is cell cycle regulated and mediated by HAT3 in Trypanosoma brucei. Mol Microbiol (2007) 1.08

Two thymidine hydroxylases differentially regulate the formation of glucosylated DNA at regions flanking polymerase II polycistronic transcription units throughout the genome of Trypanosoma brucei. Nucleic Acids Res (2010) 1.08

Mutational analysis of the variant surface glycoprotein GPI-anchor signal sequence in Trypanosoma brucei. J Cell Sci (2002) 1.05

CRE recombinase-based positive-negative selection systems for genetic manipulation in Trypanosoma brucei. Mol Biochem Parasitol (2007) 1.05

Telomere length regulation and transcriptional silencing in KU80-deficient Trypanosoma brucei. Nucleic Acids Res (2004) 1.04

MCM-BP is required for repression of life-cycle specific genes transcribed by RNA polymerase I in the mammalian infectious form of Trypanosoma brucei. PLoS One (2013) 1.03

Structural features affecting variant surface glycoprotein expression in Trypanosoma brucei. Mol Biochem Parasitol (2003) 1.00

Histone H3 trimethylated at lysine 4 is enriched at probable transcription start sites in Trypanosoma brucei. Mol Biochem Parasitol (2010) 1.00

The essential polysome-associated RNA-binding protein RBP42 targets mRNAs involved in Trypanosoma brucei energy metabolism. RNA (2012) 0.99

Trypanosoma brucei Orc1 is essential for nuclear DNA replication and affects both VSG silencing and VSG switching. Mol Microbiol (2012) 0.98

Telomere length affects the frequency and mechanism of antigenic variation in Trypanosoma brucei. PLoS Pathog (2012) 0.98

Transposon mutagenesis of Trypanosoma brucei identifies glycosylation mutants resistant to concanavalin A. J Biol Chem (2004) 0.95

Trypanosoma brucei expression-site-associated-gene-8 protein interacts with a Pumilio family protein. Mol Biochem Parasitol (2002) 0.94

Identification of Trypanosoma brucei RMI1/BLAP75 homologue and its roles in antigenic variation. PLoS One (2011) 0.94

Telomere structure and shortening in telomerase-deficient Trypanosoma brucei. Nucleic Acids Res (2005) 0.93

Trypanosome H2Bv replaces H2B in nucleosomes enriched for H3 K4 and K76 trimethylation. Biochem Biophys Res Commun (2008) 0.92

Telomerase-independent stabilization of short telomeres in Trypanosoma brucei. Mol Cell Biol (2006) 0.92

Trypanosoma brucei MRE11 is non-essential but influences growth, homologous recombination and DNA double-strand break repair. Mol Biochem Parasitol (2002) 0.92

Consequences of telomere shortening at an active VSG expression site in telomerase-deficient Trypanosoma brucei. Eukaryot Cell (2006) 0.88

Targeted deletion of the gp72 gene decreases the infectivity of Trypanosoma cruzi for mice and insect vectors. J Parasitol (2002) 0.87

Trypanosomes at the gates. Science (2005) 0.86

DOT1A-dependent H3K76 methylation is required for replication regulation in Trypanosoma brucei. Nucleic Acids Res (2012) 0.86

Strategies to construct null and conditional null Trypanosoma brucei mutants using Cre-recombinase and loxP. Mol Biochem Parasitol (2013) 0.85

An organism-specific method to rank predicted coding regions in Trypanosoma brucei. Nucleic Acids Res (2003) 0.84

Telomere length in Trypanosoma brucei. Exp Parasitol (2007) 0.81

Regulation and spatial organization of PCNA in Trypanosoma brucei. Biochem Biophys Res Commun (2012) 0.81

Trypanosoma brucei 29-13 strain is inducible in but not permissive for the tsetse fly vector. Exp Parasitol (2007) 0.80

Heterologous expression reveals distinct enzymatic activities of two DOT1 histone methyltransferases of Trypanosoma brucei. J Cell Sci (2010) 0.79

Characterization of two different Asf1 histone chaperones with distinct cellular localizations and functions in Trypanosoma brucei. Nucleic Acids Res (2013) 0.77

Reliable quantification of cell cycle-dependent mRNA abundance using fluorescence-activated cell sorting in Trypanosoma brucei. Mol Biochem Parasitol (2010) 0.77

Drug discovery: Fat-free proteins kill parasites. Nature (2010) 0.75

The naming of genes. Trends Parasitol (2011) 0.75