Irshad H Chaudry

Author PubWeight™ 205.23‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cecal ligation and puncture. Shock 2005 3.93
2 Abandon the mouse research ship? Not just yet! Shock 2014 2.60
3 Tranexamic acid and trauma: current status and knowledge gaps with recommended research priorities. Shock 2013 1.74
4 Mechanism of estrogen-mediated intestinal protection following trauma-hemorrhage: p38 MAPK-dependent upregulation of HO-1. Am J Physiol Regul Integr Comp Physiol 2008 1.61
5 Administration of human inter-alpha-inhibitors maintains hemodynamic stability and improves survival during sepsis. Crit Care Med 2002 1.60
6 Scientific priorities and strategic planning for resuscitation research and life saving therapy following traumatic injury: report of the PULSE Trauma Work Group. Acad Emerg Med 2002 1.57
7 Influence of sex and age on mods and cytokines after multiple injuries. Shock 2007 1.56
8 Mechanism of salutary effects of estrogen on cardiac function following trauma-hemorrhage: Akt-dependent HO-1 up-regulation. Crit Care Med 2009 1.52
9 Bench-to-bedside review: latest results in hemorrhagic shock. Crit Care 2008 1.47
10 Commonality and differences in leukocyte gene expression patterns among three models of inflammation and injury. Physiol Genomics 2005 1.40
11 Inhibition of Fas/Fas ligand signaling improves septic survival: differential effects on macrophage apoptotic and functional capacity. J Leukoc Biol 2003 1.39
12 Female sex hormones regulate macrophage function after trauma-hemorrhage and prevent increased death rate from subsequent sepsis. Ann Surg 2002 1.39
13 Glucosamine improves cardiac function following trauma-hemorrhage by increased protein O-GlcNAcylation and attenuation of NF-{kappa}B signaling. Am J Physiol Heart Circ Physiol 2008 1.35
14 Gender differences in acute response to trauma-hemorrhage. Shock 2005 1.34
15 Age-related gender differential in outcome after blunt or penetrating trauma. Shock 2003 1.31
16 Comparison of longitudinal leukocyte gene expression after burn injury or trauma-hemorrhage in mice. Physiol Genomics 2007 1.30
17 Gender and susceptibility to sepsis following trauma. Endocr Metab Immune Disord Drug Targets 2006 1.28
18 TLR4 regulates Kupffer cell chemokine production, systemic inflammation and lung neutrophil infiltration following trauma-hemorrhage. Mol Immunol 2007 1.28
19 The role of MAPK in Kupffer cell toll-like receptor (TLR) 2-, TLR4-, and TLR9-mediated signaling following trauma-hemorrhage. J Cell Physiol 2007 1.23
20 Sex differences in mortality after burn injury: results of analysis of the National Burn Repository of the American Burn Association. J Burn Care Res 2006 1.23
21 Kupffer cells and their mediators: the culprits in producing distant organ damage after trauma-hemorrhage. Am J Pathol 2006 1.22
22 Novel approach to prevent the transition from the hyperdynamic phase to the hypodynamic phase of sepsis: role of adrenomedullin and adrenomedullin binding protein-1. Ann Surg 2002 1.22
23 Gender differences in mortality following burn injury. Shock 2002 1.19
24 The role of estrogen and receptor agonists in maintaining organ function after trauma-hemorrhage. Shock 2009 1.19
25 Relationships between burn size, immunosuppression, and macrophage hyperactivity in a murine model of thermal injury. Cell Immunol 2002 1.18
26 When apoptosis meets autophagy: deciding cell fate after trauma and sepsis. Trends Mol Med 2009 1.17
27 The role of gammadelta T cells in the regulation of neutrophil-mediated tissue damage after thermal injury. J Leukoc Biol 2004 1.17
28 Brain death significantly reduces isolated pancreatic islet yields and functionality in vitro and in vivo after transplantation in rats. Diabetes 2003 1.17
29 Trauma and immune response--effect of gender differences. Injury 2007 1.17
30 Acute alcohol intoxication potentiates neutrophil-mediated intestinal tissue damage after burn injury. Shock 2008 1.17
31 The role of MIP-1 alpha in the development of systemic inflammatory response and organ injury following trauma hemorrhage. J Immunol 2008 1.17
32 Tissue-specific expression of estrogen receptors and their role in the regulation of neutrophil infiltration in various organs following trauma-hemorrhage. J Leukoc Biol 2006 1.16
33 G protein-coupled receptor 30-dependent protein kinase A pathway is critical in nongenomic effects of estrogen in attenuating liver injury after trauma-hemorrhage. Am J Pathol 2007 1.16
34 Trauma-hemorrhage induces depressed splenic dendritic cell functions in mice. J Immunol 2006 1.15
35 Hemorrhage induces the rapid development of hepatic insulin resistance. Am J Physiol Gastrointest Liver Physiol 2002 1.13
36 Acute alcohol intoxication increases interleukin-18-mediated neutrophil infiltration and lung inflammation following burn injury in rats. Am J Physiol Lung Cell Mol Physiol 2007 1.13
37 Upregulation of mitochondrial respiratory complex IV by estrogen receptor-beta is critical for inhibiting mitochondrial apoptotic signaling and restoring cardiac functions following trauma-hemorrhage. J Mol Cell Cardiol 2006 1.12
38 Estrogen: a novel therapeutic adjunct for the treatment of trauma-hemorrhage-induced immunological alterations. Mol Med 2008 1.11
39 Differential alterations in cardiovascular responses during the progression of polymicrobial sepsis in the mouse. Shock 2002 1.11
40 The association between gender and mortality among trauma patients as modified by age. J Trauma 2003 1.11
41 Surgical trauma and immunosuppression: pathophysiology and potential immunomodulatory approaches. Langenbecks Arch Surg 2005 1.11
42 Mechanism of cardioprotection following trauma-hemorrhagic shock by a selective estrogen receptor-beta agonist: up-regulation of cardiac heat shock factor-1 and heat shock proteins. J Mol Cell Cardiol 2005 1.10
43 Heme oxygenase-1 protects against neutrophil-mediated intestinal damage by down-regulation of neutrophil p47phox and p67phox activity and O2- production in a two-hit model of alcohol intoxication and burn injury. J Immunol 2008 1.10
44 Inhibition of IL-18 reduces myeloperoxidase activity and prevents edema in intestine following alcohol and burn injury. J Leukoc Biol 2005 1.10
45 17Beta-estradiol downregulates Kupffer cell TLR4-dependent p38 MAPK pathway and normalizes inflammatory cytokine production following trauma-hemorrhage. Mol Immunol 2006 1.09
46 Resveratrol improves cardiac contractility following trauma-hemorrhage by modulating Sirt1. Mol Med 2012 1.09
47 Metabolic modulators following trauma sepsis: sex hormones. Crit Care Med 2007 1.09
48 Keratinocyte-derived chemokine plays a critical role in the induction of systemic inflammation and tissue damage after trauma-hemorrhage. Shock 2007 1.09
49 Regulation of the postburn wound inflammatory response by gammadelta T-cells. Shock 2007 1.09
50 Src family kinases regulate p38 MAPK-mediated IL-6 production in Kupffer cells following hypoxia. Am J Physiol Cell Physiol 2006 1.08
51 The cellular basis of post-burn immunosuppression: macrophages and mediators. Int J Mol Med 2002 1.07
52 Alcohol intoxication and post-burn complications. Front Biosci 2006 1.05
53 Mechanisms of hemorrhage-induced hepatic insulin resistance: role of tumor necrosis factor-alpha. Endocrinology 2004 1.04
54 Insights into the role of interleukin-6 in the induction of hepatic injury after trauma-hemorrhagic shock. J Appl Physiol (1985) 2004 1.04
55 Adrenomedullin binding protein-1 modulates vascular responsiveness to adrenomedullin in late sepsis. Am J Physiol Regul Integr Comp Physiol 2002 1.04
56 T cells of the gammadelta T-cell receptor lineage play an important role in the postburn wound healing process. J Burn Care Res 2006 1.03
57 The PI3K/Akt pathway mediates the nongenomic cardioprotective effects of estrogen following trauma-hemorrhage. Ann Surg 2007 1.03
58 Mechanism of cardiac depression after trauma-hemorrhage: increased cardiomyocyte IL-6 and effect of sex steroids on IL-6 regulation and cardiac function. Am J Physiol Heart Circ Physiol 2004 1.03
59 Differential expression and tissue compartmentalization of the inflammatory response following thermal injury. Cytokine 2002 1.03
60 Selective inhibition of iNOS attenuates trauma-hemorrhage/resuscitation-induced hepatic injury. J Appl Physiol (1985) 2008 1.02
61 A role of PP1/PP2A in mesenteric lymph node T cell suppression in a two-hit rodent model of alcohol intoxication and injury. J Leukoc Biol 2005 1.02
62 Flutamide restores cardiac function after trauma-hemorrhage via an estrogen-dependent pathway through upregulation of PGC-1. Am J Physiol Heart Circ Physiol 2005 1.01
63 Differential fluid regulation during and after soft tissue trauma and hemorrhagic shock in males and proestrus females. Shock 2003 1.00
64 The association between sex and mortality among burn patients as modified by age. J Burn Care Rehabil 2005 1.00
65 Mechanism of IL-6-mediated cardiac dysfunction following trauma-hemorrhage. J Mol Cell Cardiol 2006 1.00
66 Are the immune responses different in middle-aged and young mice following bone fracture, tissue trauma and hemorrhage? Cytokine 2004 0.99
67 The protective effects of PUGNAc on cardiac function after trauma-hemorrhage are mediated via increased protein O-GlcNAc levels. Shock 2007 0.99
68 Inhibition of cardiac PGC-1alpha expression abolishes ERbeta agonist-mediated cardioprotection following trauma-hemorrhage. FASEB J 2006 0.99
69 Flutamide protects against trauma-hemorrhage-induced liver injury via attenuation of the inflammatory response, oxidative stress, and apopotosis. J Appl Physiol (1985) 2008 0.99
70 Impact of sex and age on bone marrow immune responses in a murine model of trauma-hemorrhage. J Appl Physiol (1985) 2006 0.98
71 Mechanism of salutary effects of estradiol on organ function after trauma-hemorrhage: upregulation of heme oxygenase. Am J Physiol Heart Circ Physiol 2005 0.98
72 A novel role for IL-18 in corticosterone-mediated intestinal damage in a two-hit rodent model of alcohol intoxication and injury. J Leukoc Biol 2006 0.98
73 Alveolar macrophage activation after trauma-hemorrhage and sepsis is dependent on NF-kappaB and MAPK/ERK mechanisms. Am J Physiol Lung Cell Mol Physiol 2002 0.97
74 Mechanism of estrogen-mediated attenuation of hepatic injury following trauma-hemorrhage: Akt-dependent HO-1 up-regulation. J Leukoc Biol 2007 0.97
75 Salutary effects of estrogen receptor-beta agonist on lung injury after trauma-hemorrhage. Am J Physiol Lung Cell Mol Physiol 2005 0.97
76 Current understanding of gender dimorphism in hepatic pathophysiology. J Surg Res 2005 0.97
77 PGC-1 upregulation via estrogen receptors: a common mechanism of salutary effects of estrogen and flutamide on heart function after trauma-hemorrhage. Am J Physiol Heart Circ Physiol 2005 0.97
78 Neutrophil chemokines and their role in IL-18-mediated increase in neutrophil O2- production and intestinal edema following alcohol intoxication and burn injury. Am J Physiol Gastrointest Liver Physiol 2009 0.96
79 Estradiol improves cardiac and hepatic function after trauma-hemorrhage: role of enhanced heat shock protein expression. Am J Physiol Regul Integr Comp Physiol 2005 0.96
80 Effect of 17beta-estradiol on signal transduction pathways and secondary damage in experimental spinal cord trauma. Shock 2008 0.96
81 Mechanism of the salutary effects of flutamide on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of estrogen receptor-{beta}-dependent HO-1. J Leukoc Biol 2005 0.95
82 Salutary effects of 17beta-estradiol on T-cell signaling and cytokine production after trauma-hemorrhage are mediated primarily via estrogen receptor-alpha. Am J Physiol Cell Physiol 2007 0.95
83 Mechanism of the nongenomic effects of estrogen on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of the PI-3K/Akt pathway. J Leukoc Biol 2007 0.95
84 Sex steroids/receptor antagonist: their use as adjuncts after trauma-hemorrhage for improving immune/cardiovascular responses and for decreasing mortality from subsequent sepsis. Anesth Analg 2008 0.95
85 Role of extracellular signal-regulated protein kinase (ERK) in 17beta-estradiol-mediated attenuation of lung injury after trauma-hemorrhage. Surgery 2008 0.95
86 The role of interleukin-10 in the regulation of the systemic inflammatory response following trauma-hemorrhage. Biochim Biophys Acta 2004 0.94
87 Effect of estrogen on mitochondrial function and intracellular stress markers in rat liver and kidney following trauma-hemorrhagic shock and prolonged hypotension. Mol Med 2010 0.94
88 Downregulation of TLR4-dependent ATP production is critical for estrogen-mediated immunoprotection in Kupffer cells following trauma-hemorrhage. J Cell Physiol 2007 0.94
89 Influence of gender and age on T-cell responses in a murine model of trauma-hemorrhage: differences between circulating and tissue-fixed cells. J Appl Physiol (1985) 2005 0.94
90 Tissue compartment-specific role of estrogen receptor subtypes in immune cell cytokine production following trauma-hemorrhage. J Appl Physiol (1985) 2006 0.94
91 Liver cytokine production and ICAM-1 expression following bone fracture, tissue trauma, and hemorrhage in middle-aged mice. Am J Physiol Gastrointest Liver Physiol 2006 0.94
92 Corticosterone suppresses mesenteric lymph node T cells by inhibiting p38/ERK pathway and promotes bacterial translocation after alcohol and burn injury. Am J Physiol Regul Integr Comp Physiol 2005 0.94
93 Gender and sex hormones influence the response to trauma and sepsis: potential therapeutic approaches. Clinics (Sao Paulo) 2006 0.93
94 Mechanism of the salutary effects of 17beta-estradiol following trauma-hemorrhage: direct downregulation of Kupffer cell proinflammatory cytokine production. Cytokine 2003 0.93
95 Flutamide attenuates pro-inflammatory cytokine production and hepatic injury following trauma-hemorrhage via estrogen receptor-related pathway. Ann Surg 2007 0.93
96 Monocyte chemoattractant protein-1 influences trauma-hemorrhage-induced distal organ damage via regulation of keratinocyte-derived chemokine production. Am J Physiol Regul Integr Comp Physiol 2006 0.92
97 17beta-Estradiol: a novel hormone for improving immune and cardiovascular responses following trauma-hemorrhage. J Leukoc Biol 2007 0.92
98 Mitochondria play an important role in 17beta-estradiol attenuation of H(2)O(2)-induced rat endothelial cell apoptosis. Am J Physiol Endocrinol Metab 2006 0.91
99 p38 MAPK-dependent eNOS upregulation is critical for 17beta-estradiol-mediated cardioprotection following trauma-hemorrhage. Am J Physiol Heart Circ Physiol 2008 0.91
100 Enhanced isolated pancreatic islet recovery and functionality in rats by 17beta-estradiol treatment of brain death donors. Surgery 2004 0.91
101 Sex differences in hepatic heme oxygenase expression and activity following trauma and hemorrhagic shock. Arch Surg 2003 0.91
102 Sex-specific p38 MAP kinase activation following trauma-hemorrhage: involvement of testosterone and estradiol. Am J Physiol Endocrinol Metab 2003 0.91
103 17 beta-estradiol administration following trauma-hemorrhage prevents the increase in Kupffer cell cytokine production and MAPK activation predominately via estrogen receptor-alpha. Surgery 2006 0.90
104 The role of the mitochondrion in trauma and shock. Shock 2004 0.90
105 Genetic variability in the immune-inflammatory response after major burn injury. Shock 2005 0.90
106 Role of p38 mitogen-activated protein kinase pathway in estrogen-mediated cardioprotection following trauma-hemorrhage. Am J Physiol Heart Circ Physiol 2007 0.90
107 Preservation of splenic immune functions by female sex hormones after trauma-hemorrhage. Crit Care Med 2002 0.90
108 Mouse genetic background influences severity of immune responses following trauma-hemorrhage. Cytokine 2005 0.90
109 Regulation of macrophage IL-10 production postinjury via beta2 integrin signaling and the P38 MAP kinase pathway. Shock 2003 0.90
110 Mechanism responsible for the salutary effects of flutamide on cardiac performance after trauma-hemorrhagic shock: Upregulation of cardiomyocyte estrogen receptors. Surgery 2005 0.90
111 Suppression of activation and costimulatory signaling in splenic CD4+ T cells after trauma-hemorrhage reduces T-cell function: a mechanism of post-traumatic immune suppression. Am J Pathol 2009 0.89
112 Sex- and diagnosis-dependent differences in mortality and admission cytokine levels among patients admitted for intensive care. Crit Care Med 2014 0.89
113 Androstenediol inhibits the trauma-hemorrhage-induced increase in caspase-3 by downregulating the inducible nitric oxide synthase pathway. J Appl Physiol (1985) 2006 0.89
114 Are the protective effects of 17beta-estradiol on splenic macrophages and splenocytes after trauma-hemorrhage mediated via estrogen-receptor (ER)-alpha or ER-beta? J Leukoc Biol 2006 0.89
115 Nitric oxide contributes to the development of a post-injury Th2 T-cell phenotype and immune dysfunction. J Cell Physiol 2006 0.89
116 Maintenance of lung myeloperoxidase activity in proestrus females after trauma-hemorrhage: upregulation of heme oxygenase-1. Am J Physiol Lung Cell Mol Physiol 2006 0.88
117 Opiate analgesics contribute to the development of post-injury immunosuppression. J Surg Res 2005 0.88
118 Sex steroid-mediated regulation of macrophage/monocyte function in a two-hit model of trauma-hemorrhage and sepsis. Cytokine 2004 0.87
119 Gender dimorphic tissue perfusion response after acute hemorrhage and resuscitation: role of vascular endothelial cell function. Am J Physiol Heart Circ Physiol 2003 0.87
120 Alcohol, burn injury, and the intestine. J Emerg Trauma Shock 2008 0.87
121 Anti-rat soluble IL-6 receptor antibody down-regulates cardiac IL-6 and improves cardiac function following trauma-hemorrhage. J Mol Cell Cardiol 2006 0.87
122 Splenectomy differentially influences immune responses in various tissue compartments of the body. Cytokine 2004 0.87
123 Adrenomedullin and adrenomedullin binding protein-1: their role in the septic response. J Surg Res 2003 0.87
124 Gender dimorphism in immune responses following trauma and hemorrhage. Immunol Res 2002 0.87
125 Mechanism for normal splenic T lymphocyte functions in proestrus females after trauma: enhanced local synthesis of 17beta-estradiol. Am J Physiol Cell Physiol 2003 0.87
126 ERK and not p38 pathway is required for IL-12 restoration of T cell IL-2 and IFN-gamma in a rodent model of alcohol intoxication and burn injury. J Immunol 2009 0.86
127 Role of thromboxane in producing hepatic injury during hepatic stress. Arch Surg 2005 0.86
128 Estrus cycle: influence on cardiac function following trauma-hemorrhage. Am J Physiol Heart Circ Physiol 2006 0.86
129 Androstenediol administration after trauma-hemorrhage attenuates inflammatory response, reduces organ damage, and improves survival following sepsis. Am J Physiol Gastrointest Liver Physiol 2006 0.86
130 Estradiol administration improves splanchnic perfusion following trauma-hemorrhage and sepsis. Arch Surg 2002 0.86
131 The role of estrogen receptor subtypes in ameliorating hepatic injury following trauma-hemorrhage. J Hepatol 2007 0.86
132 Effects of 17beta-estradiol and flutamide on splenic macrophages and splenocytes after trauma-hemorrhage. Cytokine 2007 0.86
133 Role of IL-10 in regulating proinflammatory cytokine release by Kupffer cells following trauma-hemorrhage. Am J Physiol Gastrointest Liver Physiol 2004 0.86
134 Immunomodulatory effects of dehydroepiandrosterone in proestrus female mice after trauma-hemorrhage. J Appl Physiol (1985) 2003 0.85
135 Role of thromboxane in producing portal hypertension following trauma-hemorrhage. Am J Physiol Gastrointest Liver Physiol 2003 0.85
136 Scientific priorities and strategic planning for resuscitation research and life saving therapy following traumatic injury: report of the PULSE Trauma Work Group. Post Resuscitative and Initial Utility of Life Saving Efforts. Shock 2002 0.85
137 Androstenediol ameliorates alterations in immune cells cytokine production capacity in a two-hit model of trauma-hemorrhage and sepsis. Cytokine 2006 0.85
138 Estrogen-mediated activation of non-genomic pathway improves macrophages cytokine production following trauma-hemorrhage. J Cell Physiol 2008 0.85
139 Mechanism of salutary effects of androstenediol on hepatic function after trauma-hemorrhage: role of endothelial and inducible nitric oxide synthase. Am J Physiol Gastrointest Liver Physiol 2004 0.85
140 Downregulation of migration inhibitory factor is critical for estrogen-mediated attenuation of lung tissue damage following trauma-hemorrhage. Am J Physiol Lung Cell Mol Physiol 2007 0.85
141 17 Beta-estradiol normalizes Toll receptor 4, mitogen activated protein kinases and inflammatory response in epidermal keratinocytes following trauma-hemorrhage. Mol Immunol 2007 0.84
142 Mitogen activated protein kinase (MAPK) mediates non-genomic pathway of estrogen on T cell cytokine production following trauma-hemorrhage. Cytokine 2008 0.84
143 Immunoprotection in proestrus females following trauma-hemorrhage: the pivotal role of estrogen receptors. Cell Immunol 2003 0.84
144 Gender differences in small intestinal perfusion following trauma hemorrhage: the role of endothelin-1. Am J Physiol Gastrointest Liver Physiol 2004 0.84
145 Cyclooxygenase 2-mediated suppression of macrophage interleukin-12 production after thermal injury. Am J Physiol Cell Physiol 2002 0.84
146 Role of PPARγ in the salutary effects of 17β-estradiol on Kupffer cell cytokine production following trauma-hemorrhage. J Cell Physiol 2011 0.83
147 Young and middle-age associated differences in cytokeratin expression after bone fracture, tissue trauma, and hemorrhage. Am J Surg 2007 0.83
148 Flutamide induces relaxation in large and small blood vessels. Arch Surg 2002 0.83
149 Mechanism of estrogen-mediated improvement in cardiac function after trauma-hemorrhage: p38-dependent normalization of cardiac Akt phosphorylation and glycogen levels. Shock 2008 0.83
150 MAP kinases differentially regulate the expression of macrophage hyperactivity after thermal injury. J Cell Physiol 2004 0.83
151 A role of PPAR-gamma in androstenediol-mediated salutary effects on cardiac function following trauma-hemorrhage. Ann Surg 2006 0.82
152 17beta-Estradiol's salutary effects on splenic dendritic cell functions following trauma-hemorrhage are mediated via estrogen receptor-alpha. Mol Immunol 2007 0.82
153 Effects of 17beta-estradiol and flutamide on inflammatory response and distant organ damage following trauma-hemorrhage in metestrus females. J Leukoc Biol 2006 0.82
154 Estrogen receptor-alpha predominantly mediates the salutary effects of 17beta-estradiol on splenic macrophages following trauma-hemorrhage. Am J Physiol Cell Physiol 2007 0.82
155 17beta-Estradiol inhibits keratinocyte-derived chemokine production following trauma-hemorrhage. Am J Physiol Lung Cell Mol Physiol 2006 0.82
156 17beta-Estradiol modulates vasoconstriction induced by endothelin-1 following trauma-hemorrhage. Am J Physiol Heart Circ Physiol 2007 0.82
157 Mechanism of hepatoprotection in proestrus female rats following trauma-hemorrhage: heme oxygenase-1-derived normalization of hepatic inflammatory responses. J Leukoc Biol 2009 0.82
158 Mechanism of the anti-inflammatory effect Of 17beta-estradiol on brain following trauma-hemorrhage. Shock 2010 0.82
159 Estrogen prevents intestinal inflammation after trauma-hemorrhage via downregulation of angiotensin II and angiotensin II subtype I receptor. Am J Physiol Gastrointest Liver Physiol 2008 0.82
160 Transgenic prolactin-/- mice: effect of trauma-hemorrhage on splenocyte functions. Am J Physiol Cell Physiol 2004 0.82
161 Better understanding of organ dysfunction requires proteomic involvement. J Proteome Res 2006 0.82
162 Alcohol ingestion before burn injury decreases splanchnic blood flow and oxygen delivery. Am J Physiol Heart Circ Physiol 2004 0.82
163 Progesterone administration after trauma and hemorrhagic shock improves cardiovascular responses. Crit Care Med 2003 0.82
164 Salutary effects of androstenediol on hepatic function after trauma-hemorrhage are mediated via peroxisome proliferators-activated receptor gamma. Surgery 2005 0.81
165 Lidocaine depresses splenocyte immune functions following trauma-hemorrhage in mice. Am J Physiol Cell Physiol 2006 0.81
166 Trauma-hemorrhage and hypoxia differentially influence kupffer cell phagocytic capacity: role of hypoxia-inducible-factor-1alpha and phosphoinositide 3-kinase/Akt activation. Ann Surg 2009 0.81
167 17β-estradiol confers protection after traumatic brain injury in the rat and involves activation of G protein-coupled estrogen receptor 1. J Neurotrauma 2013 0.81
168 Mechanism of salutary effects of finasteride on post-traumatic immune/inflammatory response: upregulation of estradiol synthesis. Ann Surg 2007 0.81
169 Differential alterations in intestinal permeability after trauma-hemorrhage. J Surg Res 2003 0.81
170 Liver X receptor protects against liver injury in sepsis caused by rodent cecal ligation and puncture. Surg Infect (Larchmt) 2011 0.81
171 Administration of progesterone after trauma and hemorrhagic shock prevents hepatocellular injury. Arch Surg 2003 0.81
172 Role of estrogen receptor subtypes in estrogen-induced organ-specific vasorelaxation after trauma-hemorrhage. Am J Physiol Heart Circ Physiol 2008 0.81
173 Estrogen suppresses cardiac IL-6 after trauma-hemorrhage via a hypoxia-inducible factor 1 alpha-mediated pathway. Shock 2009 0.81
174 Mechanism of the salutary effects of estrogen on kupffer cell phagocytic capacity following trauma-hemorrhage: pivotal role of Akt activation. J Immunol 2009 0.81
175 MyD88 and Src are differentially regulated in Kupffer cells of males and proestrus females following hypoxia. Mol Med 2006 0.81
176 Effect of estradiol administration on splanchnic perfusion after trauma-hemorrhage and sepsis. Curr Opin Crit Care 2003 0.81
177 The effects of estrogen on various organs: therapeutic approach for sepsis, trauma, and reperfusion injury. Part 2: liver, intestine, spleen, and kidney. J Anesth 2012 0.81
178 Effect of interleukin-15 on depressed splenic dendritic cell functions following trauma-hemorrhage. Am J Physiol Cell Physiol 2008 0.80
179 Dehydroepiandrosterone restores depressed peripheral blood mononuclear cell function following major abdominal surgery via the estrogen receptors. Crit Care Med 2005 0.80
180 Single photon emission computed tomography demonstrated efficacy of 17β-estradiol therapy in male rats after trauma-hemorrhage and extended hypotension. J Trauma 2010 0.80
181 Does estrogen contribute to the hepatic regeneration following portal branch ligation in rats? Am J Physiol Gastrointest Liver Physiol 2006 0.80
182 Dehydroepiandrosterone modulates toll-like receptor expression on splenic macrophages of mice after severe polymicrobial sepsis. Shock 2005 0.80
183 The effect of inhibition of a major cell signaling pathway following trauma hemorrhage on hepatic injury and interleukin 6 levels. Arch Surg 2004 0.80
184 Alpha1-acid-glycoprotein protects against trauma-hemorrhagic shock. J Surg Res 2004 0.79
185 Trauma-hemorrhage inhibits splenic dendritic cell proinflammatory cytokine production via a mitogen-activated protein kinase process. Am J Physiol Cell Physiol 2008 0.79
186 Estrogen pretreatment protects males against hypoxia-induced immune depression. Am J Physiol Cell Physiol 2002 0.79
187 Gender differences in small intestinal endothelial function: inhibitory role of androgens. Am J Physiol Gastrointest Liver Physiol 2003 0.79
188 Salutary effects of androstenediol on cardiac function and splanchnic perfusion after trauma-hemorrhage. Am J Physiol Regul Integr Comp Physiol 2004 0.79
189 Lidocaine enhances apoptosis and suppresses mitochondrial functions of human neutrophil in vitro. J Trauma 2010 0.79
190 The role of estrogen receptor subtypes on hepatic neutrophil accumulation following trauma-hemorrhage: direct modulation of CINC-1 production by Kupffer cells. Cytokine 2008 0.79
191 Systematic analysis of the salutary effect of estrogen on cardiac performance after trauma-hemorrhage. Shock 2008 0.78
192 The effects of estrogen on various organs: therapeutic approach for sepsis, trauma, and reperfusion injury. Part 1: central nervous system, lung, and heart. J Anesth 2012 0.78
193 Estrogen ameliorates trauma-hemorrhage-induced lung injury via endothelial nitric oxide synthase-dependent activation of protein kinase G. Ann Surg 2008 0.78
194 Decreased 5alpha-dihydrotestosterone catabolism suppresses T lymphocyte functions in males after trauma-hemorrhage. Am J Physiol Cell Physiol 2002 0.78
195 Efficacy of 17α-ethynylestradiol-3-sulfate for severe hemorrhage in minipigs in the absence of fluid resuscitation. J Trauma Acute Care Surg 2014 0.78
196 Surgical trauma-induced adrenal insufficiency is associated with postoperative inflammatory responses. J Nippon Med Sch 2007 0.77
197 Does gender influence outcomes in critically ill patients? Crit Care 2012 0.77
198 Saturation of adrenomedullin receptors plays an important role in reducing pulmonary clearance of adrenomedullin during the late stage of sepsis. Biochim Biophys Acta 2002 0.77
199 A role for corticosterone in impaired intestinal immunity and barrier function in a rodent model of acute alcohol intoxication and burn injury. J Neuroimmune Pharmacol 2006 0.77
200 Lidocaine suppresses mouse Peyer's Patch T cell functions and induces bacterial translocation. Surgery 2010 0.77
201 Hepatoprotective effect of casodex after trauma hemorrhage in a rodent model. Shock 2015 0.77
202 L-arginine: a unique amino acid for improving depressed wound immune function following hemorrhage. Eur Surg Res 2002 0.77
203 Metabolic disturbances in shock, and the role of ATP-MgCl2 and sex steroids. Med Princ Pract 2003 0.77
204 The ERRor of Our Ways: Estrogen-Related Receptors are About Energy, Not Hormones, and are Potential New Targets for Trauma and Shock. Shock 2015 0.76
205 Androgen-mediated modulation of macrophage function after trauma-hemorrhage: central role of 5alpha-dihydrotestosterone. J Appl Physiol (1985) 2003 0.76
206 Salutary effects of 17beta-estradiol on Peyer's patch T cell functions following trauma-hemorrhage. Cytokine 2010 0.76
207 Upregulation of hepatic prolactin receptor gene expression by 17beta-estradiol following trauma-hemorrhage. J Appl Physiol (1985) 2003 0.76
208 Estradiol's effect on portal response to endothelin-1 after trauma-hemorrhage. J Surg Res 2004 0.75
209 Hepatic gene expression patterns following trauma-hemorrhage: effect of posttreatment with estrogen. Shock 2013 0.75
210 The potential role of T-cells and their interaction with antigen-presenting cells in mediating immunosuppression following trauma-hemorrhage. Innate Immun 2009 0.75
211 Estradiol's salutary effects on keratinocytes following trauma-hemorrhage are mediated by estrogen receptor (ER)-alpha and ER-beta. Mol Med 2008 0.75
212 Inhibition of protein tyrosine phosphatases prevents mesenteric lymph node T-cell suppression following alcohol intoxication and burn injury. J Burn Care Res 2008 0.75
213 Hepatoprotective Effects of Corilagin Following Hemorrhagic Shock are Through Akt-Dependent Pathway. Shock 2017 0.75
214 The Role and Use of Estrogens Following Trauma. Shock 2016 0.75
215 Trauma-haemorrhage-induced alterations in thymic prolactin receptor expression: implications in immune dysfunction. Cytokine 2002 0.75
216 Physiological levels of 5 alpha-dihydrotestosterone depress wound immune function and impair wound healing following trauma-hemorrhage. Arch Surg 2004 0.75