Published in Genomics on June 01, 2004
Cell-type specific gene expression profiles of leukocytes in human peripheral blood. BMC Genomics (2006) 3.27
Natural variation in cardiac metabolism and gene expression in Fundulus heteroclitus. Nat Genet (2004) 2.75
A common gene signature across multiple studies relate biomarkers and functional regulation in tolerance to renal allograft. Kidney Int (2015) 2.02
Microarray analysis of human leucocyte subsets: the advantages of positive selection and rapid purification. BMC Genomics (2007) 1.74
Elevating the perspective on human stress genomics. Psychoneuroendocrinology (2010) 1.53
Relation of platelet and leukocyte inflammatory transcripts to body mass index in the Framingham heart study. Circulation (2010) 1.47
Sources of variation in baseline gene expression levels from toxicogenomics study control animals across multiple laboratories. BMC Genomics (2008) 1.33
Deciphering normal blood gene expression variation--The NOWAC postgenome study. PLoS Genet (2010) 1.29
Variability of gene expression profiles in human blood and lymphoblastoid cell lines. BMC Genomics (2010) 1.22
Effect of acute physiological hyperinsulinemia on gene expression in human skeletal muscle in vivo. Am J Physiol Endocrinol Metab (2008) 1.17
A longitudinal study of gene expression in healthy individuals. BMC Med Genomics (2009) 1.11
Arguments for the sake of endophenotypes: examining common misconceptions about the use of endophenotypes in psychiatric genetics. Am J Med Genet B Neuropsychiatr Genet (2014) 1.08
The effect of food intake on gene expression in human peripheral blood. Hum Mol Genet (2010) 1.02
Blood-based gene expression signatures of infants and toddlers with autism. J Am Acad Child Adolesc Psychiatry (2012) 1.01
Haloperidol treatment induces tissue- and sex-specific changes in DNA methylation: a control study using rats. Behav Brain Funct (2006) 1.01
CD28-inducible transcription factor DEC1 is required for efficient autoreactive CD4+ T cell response. J Exp Med (2013) 0.98
Blood transcriptomic biomarkers in adult primary care patients with major depressive disorder undergoing cognitive behavioral therapy. Transl Psychiatry (2014) 0.96
Limited dynamic range of immune response gene expression observed in healthy blood donors using RT-PCR. Mol Med (2006) 0.94
Relationship among circulating inflammatory proteins, platelet gene expression, and cardiovascular risk. Arterioscler Thromb Vasc Biol (2013) 0.94
Investigation of variation in gene expression profiling of human blood by extended principle component analysis. PLoS One (2011) 0.93
Gene expression signatures of radiation exposure in peripheral white blood cells of smokers and non-smokers. Int J Radiat Biol (2011) 0.91
The effect of genetic and environmental variation on metabolic gene expression. Mol Ecol (2009) 0.88
Biomarker investigations related to pathophysiological pathways in schizophrenia and psychosis. Front Cell Neurosci (2013) 0.87
Gene expression profile of peripheral blood lymphocytes from renal cell carcinoma patients treated with IL-2, interferon-α and dendritic cell vaccine. PLoS One (2012) 0.86
A "crossomics" study analysing variability of different components in peripheral blood of healthy caucasoid individuals. PLoS One (2012) 0.86
The effects of globin on microarray-based gene expression analysis of mouse blood. Mamm Genome (2010) 0.85
Whole genome transcript profiling from fingerstick blood samples: a comparison and feasibility study. BMC Genomics (2009) 0.84
Assessing individual differences in genome-wide gene expression in human whole blood: reliability over four hours and stability over 10 months. Twin Res Hum Genet (2009) 0.83
Use of gene expression profiles of peripheral blood lymphocytes to distinguish BRCA1 mutation carriers in high risk breast cancer families. Cancer Inform (2009) 0.81
Omic personality: implications of stable transcript and methylation profiles for personalized medicine. Genome Med (2015) 0.81
Concordant gene expression in leukemia cells and normal leukocytes is associated with germline cis-SNPs. PLoS One (2008) 0.80
Using blood gene signatures for assessing effects of exposure to perfluoroalkyl acids (PFAAs) in humans: the NOWAC postgenome study. Int J Mol Epidemiol Genet (2011) 0.78
Variation analysis of transcriptome changes reveals cochlear genes and their associated functions in cochlear susceptibility to acoustic overstimulation. Hear Res (2015) 0.77
An easy operating pathogen microarray (EOPM) platform for rapid screening of vertebrate pathogens. BMC Infect Dis (2013) 0.77
Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 h fast provides evidence of effects on genes regulating inflammation, apoptosis and energy metabolism. Genes Nutr (2014) 0.77
Genome-Wide Profiling of RNA from Dried Blood Spots: Convergence with Bioinformatic Results Derived from Whole Venous Blood and Peripheral Blood Mononuclear Cells. Biodemography Soc Biol (2016) 0.76
Improving power to detect changes in blood miRNA expression by accounting for sources of variability in experimental designs. Cancer Epidemiol Biomarkers Prev (2014) 0.76
Interactions between the tumor and the blood systemic response of breast cancer patients. PLoS Comput Biol (2017) 0.75
Gene expression profiling predicts clinical outcome of breast cancer. Nature (2002) 71.36
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature (2005) 48.95
Functional profiling of the Saccharomyces cerevisiae genome. Nature (2002) 36.10
Genetics of gene expression surveyed in maize, mouse and man. Nature (2003) 22.17
A microRNA component of the p53 tumour suppressor network. Nature (2007) 19.25
Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays. Science (2003) 16.80
Expression profiling reveals off-target gene regulation by RNAi. Nat Biotechnol (2003) 16.63
An integrative genomics approach to infer causal associations between gene expression and disease. Nat Genet (2005) 11.40
A large-scale RNAi screen in human cells identifies new components of the p53 pathway. Nature (2004) 8.67
Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity. RNA (2006) 7.06
Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression. Mol Cell Biol (2007) 6.43
CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms. Mol Cell Biol (2005) 6.18
Minimizing the risk of reporting false positives in large-scale RNAi screens. Nat Methods (2006) 5.96
Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer. Nat Genet (2011) 5.68
MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol Cell Biol (2008) 5.21
Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm. Cell (2012) 5.16
Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell (2004) 4.91
MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression. Mol Cell Biol (2008) 4.76
Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing. RNA (2006) 4.72
Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application. Nat Rev Drug Discov (2010) 4.25
Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2. Genes Dev (2008) 4.24
Integrated genomic and proteomic analyses of gene expression in Mammalian cells. Mol Cell Proteomics (2004) 4.09
Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet (2012) 4.07
Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties. Am J Transplant (2005) 4.05
miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice. J Exp Med (2011) 3.78
Gene expression changes associated with progression and response in chronic myeloid leukemia. Proc Natl Acad Sci U S A (2006) 3.70
Synthetic shRNAs as potent RNAi triggers. Nat Biotechnol (2004) 3.67
Genomic portrait of resectable hepatocellular carcinomas: implications of RB1 and FGF19 aberrations for patient stratification. Hepatology (2014) 3.31
Designing siRNA that distinguish between genes that differ by a single nucleotide. PLoS Genet (2006) 3.23
MicroRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT. Cell Cycle (2009) 3.07
Coordinated regulation of cell cycle transcripts by p53-Inducible microRNAs, miR-192 and miR-215. Cancer Res (2008) 2.86
Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies. Nat Methods (2007) 2.83
Use of hybridization kinetics for differentiating specific from non-specific binding to oligonucleotide microarrays. Nucleic Acids Res (2002) 2.77
A cell proliferation signature is a marker of extremely poor outcome in a subpopulation of breast cancer patients. Cancer Res (2005) 2.65
MicroRNAs and cell cycle regulation. Cell Cycle (2007) 2.62
Gene expression profiling in patients with chronic obstructive pulmonary disease and lung cancer. Am J Respir Crit Care Med (2007) 2.39
Noise amidst the silence: off-target effects of siRNAs? Trends Genet (2004) 2.38
Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors. Proc Natl Acad Sci U S A (2002) 2.32
A comprehensive transcript index of the human genome generated using microarrays and computational approaches. Genome Biol (2004) 2.21
The peroxidase activity of mitochondrial superoxide dismutase. Free Radic Biol Med (2012) 2.14
Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma. Genome Res (2013) 2.12
Median absolute deviation to improve hit selection for genome-scale RNAi screens. J Biomol Screen (2008) 2.12
Haploinsufficiency-based large-scale forward genetic analysis of filamentous growth in the diploid human fungal pathogen C.albicans. EMBO J (2003) 2.11
Attenuation of gammadeltaTCR signaling efficiently diverts thymocytes to the alphabeta lineage. Immunity (2005) 2.11
Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions. Mol Cell Biol (2006) 1.97
Myc-regulated microRNAs attenuate embryonic stem cell differentiation. EMBO J (2009) 1.94
The hypoxia-inducible factor 2alpha N-terminal and C-terminal transactivation domains cooperate to promote renal tumorigenesis in vivo. Mol Cell Biol (2007) 1.92
T lymphocyte activation gene identification by coregulated expression on DNA microarrays. Genomics (2004) 1.86
RNA-Seq Atlas--a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics (2012) 1.74
microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma. Mol Syst Biol (2010) 1.69
Expression of alternatively spliced sodium channel alpha-subunit genes. Unique splicing patterns are observed in dorsal root ganglia. J Biol Chem (2004) 1.67
Functional genomics identifies therapeutic targets for MYC-driven cancer. Proc Natl Acad Sci U S A (2012) 1.65
Hypoxia-inducible factor linked to differential kidney cancer risk seen with type 2A and type 2B VHL mutations. Mol Cell Biol (2007) 1.62
Effect of apolipoprotein E genotype and diet on apolipoprotein E lipidation and amyloid peptides: randomized clinical trial. JAMA Neurol (2013) 1.52
Genetic context determines susceptibility to intraocular pressure elevation in a mouse pigmentary glaucoma. BMC Biol (2006) 1.52
Predicting prognosis in hepatocellular carcinoma after curative surgery with common clinicopathologic parameters. BMC Cancer (2009) 1.49
Galaxy LIMS for next-generation sequencing. Bioinformatics (2013) 1.45
Signatures of environmental exposures using peripheral leukocyte gene expression: tobacco smoke. Cancer Epidemiol Biomarkers Prev (2004) 1.44
Pillars article: T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1. 1990. Proc. Natl. Acad. Sci. USA 87: 5031-5035. J Immunol (2009) 1.43
Lymphoma chemovirotherapy: CD20-targeted and convertase-armed measles virus can synergize with fludarabine. Cancer Res (2007) 1.41
DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival. J Biol Chem (2011) 1.40
Pillars article: long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways. Nature. 1996. 381: 434-438. 1996. J Immunol (2011) 1.39
Carbon Dioxide versus Saline Tissue Expanders: Does It Matter? Plast Reconstr Surg (2016) 1.36
Comparative expression pathway analysis of human and canine mammary tumors. BMC Genomics (2009) 1.35
Targeting cadherin-17 inactivates Wnt signaling and inhibits tumor growth in liver carcinoma. Hepatology (2009) 1.32
Pathway and gene-set activation measurement from mRNA expression data: the tissue distribution of human pathways. Genome Biol (2006) 1.29
MicroRNA-like off-target transcript regulation by siRNAs is species specific. RNA (2009) 1.27
Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting. PLoS One (2011) 1.26
Genomic landscape of copy number aberrations enables the identification of oncogenic drivers in hepatocellular carcinoma. Hepatology (2013) 1.26
RNA interference-mediated silencing of mitotic kinesin KIF14 disrupts cell cycle progression and induces cytokinesis failure. Mol Cell Biol (2006) 1.23
An immunocompetent murine model for oncolysis with an armed and targeted measles virus. Mol Ther (2007) 1.21
Identification of SULF2 as a novel transcriptional target of p53 by use of integrated genomic analyses. Cancer Res (2009) 1.18
Nitric oxide-dependent Src activation and resultant caveolin-1 phosphorylation promote eNOS/caveolin-1 binding and eNOS inhibition. Mol Biol Cell (2012) 1.16
Diet intervention and cerebrospinal fluid biomarkers in amnestic mild cognitive impairment. Arch Neurol (2011) 1.15
Claudin-18 gene structure, regulation, and expression is evolutionary conserved in mammals. Gene (2011) 1.14
Comparison of different miR-21 inhibitor chemistries in a cardiac disease model. J Clin Invest (2011) 1.10
A comprehensive characterization of genome-wide copy number aberrations in colorectal cancer reveals novel oncogenes and patterns of alterations. PLoS One (2012) 1.08
Prognostic significance and therapeutic potential of eukaryotic translation initiation factor 5A (eIF5A) in hepatocellular carcinoma. Int J Cancer (2010) 1.08
Transcriptional and phenotypic comparisons of Ppara knockout and siRNA knockdown mice. Nucleic Acids Res (2006) 1.08
Next generation sequencing reveals genetic landscape of hepatocellular carcinomas. Cancer Lett (2012) 1.05
Food and botanical groupings and risk of breast cancer: a case-control study in Shanghai, China. Cancer Epidemiol Biomarkers Prev (2005) 1.05
Multiplexed gene expression and fusion transcript analysis to detect ALK fusions in lung cancer. J Mol Diagn (2012) 1.03
HIVID: an efficient method to detect HBV integration using low coverage sequencing. Genomics (2013) 1.02
Lyst mutation in mice recapitulates iris defects of human exfoliation syndrome. Invest Ophthalmol Vis Sci (2008) 1.00
Prediction of disease-free survival in hepatocellular carcinoma by gene expression profiling. Ann Surg Oncol (2013) 0.98
Off-target and a portion of target-specific siRNA mediated mRNA degradation is Ago2 'Slicer' independent and can be mediated by Ago1. Nucleic Acids Res (2009) 0.97