Published in Mol Cell on June 18, 2004
Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans. Cell (2007) 3.06
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The microtubule nucleation activity of centrobin in both the centrosome and cytoplasm. Cell Cycle (2015) 0.75
Loss of a doublecortin (DCX) domain protein causes structural defects in a tubulin-based organelle of Toxoplasma gondii and impairs host-cell invasion. Mol Biol Cell (2016) 0.75
Studies of HVC Plasticity in Adult Canaries Reveal Social Effects and Sex Differences as Well as Limitations of Multiple Markers Available to Assess Adult Neurogenesis. PLoS One (2017) 0.75
Everolimus Stabilizes Podocyte Microtubules via Enhancing TUBB2B and DCDC2 Expression. PLoS One (2015) 0.75
Dynamic microtubule association of Doublecortin X (DCX) is regulated by its C-terminus. Sci Rep (2017) 0.75
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Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells. Nature (2007) 4.87
A structural state of the myosin V motor without bound nucleotide. Nature (2003) 3.63
Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle. EMBO J (2002) 3.53
Three myosin V structures delineate essential features of chemo-mechanical transduction. EMBO J (2004) 3.21
Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans. Cell (2007) 3.06
Mutations in the beta-tubulin gene TUBB2B result in asymmetrical polymicrogyria. Nat Genet (2009) 3.01
Mutations in the JARID1C gene, which is involved in transcriptional regulation and chromatin remodeling, cause X-linked mental retardation. Am J Hum Genet (2004) 2.99
Genotype-phenotype analysis in 2,405 patients with a dystrophinopathy using the UMD-DMD database: a model of nationwide knowledgebase. Hum Mutat (2009) 2.93
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Structural and functional insights into the Myosin motor mechanism. Annu Rev Biophys (2010) 2.55
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Insights into antiparallel microtubule crosslinking by PRC1, a conserved nonmotor microtubule binding protein. Cell (2010) 2.50
The structure of the myosin VI motor reveals the mechanism of directionality reversal. Nature (2005) 2.50
Molecular genetics of Rett syndrome: when DNA methylation goes unrecognized. Nat Rev Genet (2006) 2.42
Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle. Nat Struct Biol (2002) 2.38
ARX, a novel Prd-class-homeobox gene highly expressed in the telencephalon, is mutated in X-linked mental retardation. Hum Mol Genet (2002) 2.30
Large spectrum of lissencephaly and pachygyria phenotypes resulting from de novo missense mutations in tubulin alpha 1A (TUBA1A). Hum Mutat (2007) 2.24
The structure of the rigor complex and its implications for the power stroke. Philos Trans R Soc Lond B Biol Sci (2004) 2.17
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MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments. J Cell Biol (2002) 2.04
A mechanism for microtubule depolymerization by KinI kinesins. Mol Cell (2002) 1.95
Griscelli syndrome restricted to hypopigmentation results from a melanophilin defect (GS3) or a MYO5A F-exon deletion (GS1). J Clin Invest (2003) 1.93
Mutations in the small GTPase gene RAB39B are responsible for X-linked mental retardation associated with autism, epilepsy, and macrocephaly. Am J Hum Genet (2010) 1.87
Visualizing ribosome biogenesis: parallel assembly pathways for the 30S subunit. Science (2010) 1.84
Mutations in the neuronal ß-tubulin subunit TUBB3 result in malformation of cortical development and neuronal migration defects. Hum Mol Genet (2010) 1.83
Submicroscopic duplications of the hydroxysteroid dehydrogenase HSD17B10 and the E3 ubiquitin ligase HUWE1 are associated with mental retardation. Am J Hum Genet (2008) 1.80
Detection of exonic copy-number changes using a highly efficient oligonucleotide-based comparative genomic hybridization-array method. Hum Mutat (2008) 1.78
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A lever-arm rotation drives motility of the minus-end-directed kinesin Ncd. Nature (2005) 1.64
Mutations in the polyglutamine binding protein 1 gene cause X-linked mental retardation. Nat Genet (2003) 1.61
A pseudoatomic model of the dynamin polymer identifies a hydrolysis-dependent powerstroke. Cell (2011) 1.59
Key clinical features to identify girls with CDKL5 mutations. Brain (2008) 1.59
The structural basis for the large powerstroke of myosin VI. Cell (2007) 1.56
The motor mechanism of myosin V: insights for muscle contraction. Philos Trans R Soc Lond B Biol Sci (2004) 1.53
Mutations in the ZNF41 gene are associated with cognitive deficits: identification of a new candidate for X-linked mental retardation. Am J Hum Genet (2003) 1.52
Orientation and structure of the Ndc80 complex on the microtubule lattice. J Cell Biol (2008) 1.51
Mutation screening in 86 known X-linked mental retardation genes by droplet-based multiplex PCR and massive parallel sequencing. Hugo J (2010) 1.50
Structural basis for recruitment of Rab6-interacting protein 1 to Golgi via a RUN domain. Structure (2009) 1.50
Mutation of the diamond-blackfan anemia gene Rps7 in mouse results in morphological and neuroanatomical phenotypes. PLoS Genet (2013) 1.50
Loss of X-linked mental retardation gene oligophrenin1 in mice impairs spatial memory and leads to ventricular enlargement and dendritic spine immaturity. J Neurosci (2007) 1.48
Transcription factor SOX3 is involved in X-linked mental retardation with growth hormone deficiency. Am J Hum Genet (2002) 1.45
Branching and nucleokinesis defects in migrating interneurons derived from doublecortin knockout mice. Hum Mol Genet (2006) 1.44
Myosin VI rewrites the rules for myosin motors. Cell (2010) 1.43
Mutations in the β-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities. Cell Rep (2012) 1.43
Myosin VI dimerization triggers an unfolding of a three-helix bundle in order to extend its reach. Mol Cell (2009) 1.42
Magnesium regulates ADP dissociation from myosin V. J Biol Chem (2004) 1.42
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Template-free 13-protofilament microtubule-MAP assembly visualized at 8 A resolution. J Cell Biol (2010) 1.38
The unique insert in myosin VI is a structural calcium-calmodulin binding site. Proc Natl Acad Sci U S A (2004) 1.38
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The unique insert at the end of the myosin VI motor is the sole determinant of directionality. Proc Natl Acad Sci U S A (2007) 1.30
GPR56-related bilateral frontoparietal polymicrogyria: further evidence for an overlap with the cobblestone complex. Brain (2010) 1.30
Mutations in the FTSJ1 gene coding for a novel S-adenosylmethionine-binding protein cause nonsyndromic X-linked mental retardation. Am J Hum Genet (2004) 1.29
Cell-autonomous roles of ARX in cell proliferation and neuronal migration during corticogenesis. J Neurosci (2008) 1.28
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Neuropathological phenotype of a distinct form of lissencephaly associated with mutations in TUBA1A. Brain (2008) 1.26
Mutation of plasma membrane Ca2+ ATPase isoform 3 in a family with X-linked congenital cerebellar ataxia impairs Ca2+ homeostasis. Proc Natl Acad Sci U S A (2012) 1.26
Structural basis for ARF1-mediated recruitment of ARHGAP21 to Golgi membranes. EMBO J (2007) 1.24
Human disorders of cortical development: from past to present. Eur J Neurosci (2006) 1.23
Distinct conformations of the kinesin Unc104 neck regulate a monomer to dimer motor transition. J Cell Biol (2003) 1.23
FACL4, encoding fatty acid-CoA ligase 4, is mutated in nonspecific X-linked mental retardation. Nat Genet (2002) 1.23
Human RTEL1 deficiency causes Hoyeraal-Hreidarsson syndrome with short telomeres and genome instability. Hum Mol Genet (2013) 1.23
MAP2c, but not tau, binds and bundles F-actin via its microtubule binding domain. Curr Biol (2004) 1.22
Differentially activated macrophages orchestrate myogenic precursor cell fate during human skeletal muscle regeneration. Stem Cells (2013) 1.22
Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles. Nucleic Acids Res (2003) 1.21
Lucky 13-microtubule depolymerisation by kinesin-13 motors. J Cell Sci (2006) 1.21
IL1 receptor accessory protein like, a protein involved in X-linked mental retardation, interacts with Neuronal Calcium Sensor-1 and regulates exocytosis. Hum Mol Genet (2003) 1.19
The role of the kinesin-13 neck in microtubule depolymerization. Cell Cycle (2006) 1.19
Neuroanatomical distribution of ARX in brain and its localisation in GABAergic neurons. Brain Res Mol Brain Res (2004) 1.19
Revised spectrum of mutations in sarcoglycanopathies. Eur J Hum Genet (2008) 1.17
Distinct roles of doublecortin modulating the microtubule cytoskeleton. EMBO J (2006) 1.16