Published in Cell on May 14, 2010
A rare variant in MYH6 is associated with high risk of sick sinus syndrome. Nat Genet (2011) 3.94
The nucleoskeleton as a genome-associated dynamic 'network of networks'. Nat Rev Mol Cell Biol (2011) 2.01
Dynein achieves processive motion using both stochastic and coordinated stepping. Nat Struct Mol Biol (2012) 1.98
Real-time monitoring of cell elasticity reveals oscillating myosin activity. Biophys J (2010) 1.19
A role for myosin VI in the localization of axonal proteins. PLoS Biol (2011) 1.14
Two single-headed myosin V motors bound to a tetrameric adapter protein form a processive complex. J Cell Biol (2011) 1.03
Evolution and classification of myosins, a paneukaryotic whole-genome approach. Genome Biol Evol (2014) 1.02
Detailed tuning of structure and intramolecular communication are dispensable for processive motion of myosin VI. Biophys J (2011) 1.00
Coiled-coil response to mechanical force: global stability and local cracking. Biophys J (2013) 0.98
Myosin motors at neuronal synapses: drivers of membrane transport and actin dynamics. Nat Rev Neurosci (2013) 0.97
Actin in hair cells and hearing loss. Hear Res (2011) 0.95
Vasoactive agonists exert dynamic and coordinated effects on vascular smooth muscle cell elasticity, cytoskeletal remodelling and adhesion. J Physiol (2014) 0.95
A master switch couples Mg²⁺-assisted catalysis to domain motion in B. stearothermophilus tryptophanyl-tRNA Synthetase. Structure (2012) 0.93
Myosin VI must dimerize and deploy its unusual lever arm in order to perform its cellular roles. Cell Rep (2014) 0.90
Multifunctional myosin VI has a multitude of cargoes. Proc Natl Acad Sci U S A (2011) 0.88
Modeling stochastic kinetics of molecular machines at multiple levels: from molecules to modules. Biophys J (2013) 0.87
Myosins, Actin and Autophagy. Traffic (2016) 0.86
Myosin-Va and dynamic actin oppose microtubules to drive long-range organelle transport. Curr Biol (2014) 0.85
Myosin VI in skeletal muscle: its localization in the sarcoplasmic reticulum, neuromuscular junction and muscle nuclei. Histochem Cell Biol (2012) 0.85
Lever-arm mechanics of processive myosins. Biophys J (2011) 0.85
Myosin VI deafness mutation prevents the initiation of processive runs on actin. Proc Natl Acad Sci U S A (2015) 0.84
Extension of a three-helix bundle domain of myosin VI and key role of calmodulins. Biophys J (2011) 0.82
Actin acting at the Golgi. Histochem Cell Biol (2013) 0.82
Processive steps in the reverse direction require uncoupling of the lead head lever arm of myosin VI. Mol Cell (2012) 0.80
Myosin VI regulates actin structure specialization through conserved cargo-binding domain sites. PLoS One (2011) 0.80
Involvement of unconventional myosin VI in myoblast function and myotube formation. Histochem Cell Biol (2015) 0.79
Molecular motors: forty years of interdisciplinary research. Mol Biol Cell (2011) 0.79
Myosin S2 origins track evolution of strong binding on actin by azimuthal rolling of motor domain. Biophys J (2015) 0.78
Insight into the role of Ca2+-binding protein 5 in vesicle exocytosis. Invest Ophthalmol Vis Sci (2011) 0.77
The myosin X motor is optimized for movement on actin bundles. Nat Commun (2016) 0.77
A pre-embedding immunogold approach reveals localization of myosin VI at the ultrastructural level in the actin cones that mediate Drosophila spermatid individualization. Protoplasma (2011) 0.76
A Kinase Anchoring Protein 9 Is a Novel Myosin VI Binding Partner That Links Myosin VI with the PKA Pathway in Myogenic Cells. Biomed Res Int (2015) 0.76
The path to visualization of walking myosin V by high-speed atomic force microscopy. Biophys Rev (2014) 0.76
Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain. Nat Struct Mol Biol (2016) 0.75
Structure of actomyosin rigour complex at 5.2 Å resolution and insights into the ATPase cycle mechanism. Nat Commun (2017) 0.75
Membrane-induced lever arm expansion allows myosin VI to walk with large and variable step sizes. J Biol Chem (2012) 0.75
Highly selective inhibition of myosin motors provides the basis of potential therapeutic application. Proc Natl Acad Sci U S A (2016) 0.75
The acquisition of mechano-electrical transducer current adaptation in auditory hair cells requires myosin VI. J Physiol (2016) 0.75
Investigations of human myosin VI targeting using optogenetically controlled cargo loading. Proc Natl Acad Sci U S A (2017) 0.75
A structural state of the myosin V motor without bound nucleotide. Nature (2003) 3.63
Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle. EMBO J (2002) 3.53
Three myosin V structures delineate essential features of chemo-mechanical transduction. EMBO J (2004) 3.21
Structural and functional insights into the Myosin motor mechanism. Annu Rev Biophys (2010) 2.55
The structure of the myosin VI motor reveals the mechanism of directionality reversal. Nature (2005) 2.50
The structure of the rigor complex and its implications for the power stroke. Philos Trans R Soc Lond B Biol Sci (2004) 2.17
Griscelli syndrome restricted to hypopigmentation results from a melanophilin defect (GS3) or a MYO5A F-exon deletion (GS1). J Clin Invest (2003) 1.93
What can myosin VI do in cells? Curr Opin Cell Biol (2006) 1.77
The structural basis for the large powerstroke of myosin VI. Cell (2007) 1.56
The motor mechanism of myosin V: insights for muscle contraction. Philos Trans R Soc Lond B Biol Sci (2004) 1.53
Mechanism of microtubule stabilization by doublecortin. Mol Cell (2004) 1.52
Structural basis for recruitment of Rab6-interacting protein 1 to Golgi via a RUN domain. Structure (2009) 1.50
Myosin VI dimerization triggers an unfolding of a three-helix bundle in order to extend its reach. Mol Cell (2009) 1.42
Magnesium regulates ADP dissociation from myosin V. J Biol Chem (2004) 1.42
Template-free 13-protofilament microtubule-MAP assembly visualized at 8 A resolution. J Cell Biol (2010) 1.38
The unique insert in myosin VI is a structural calcium-calmodulin binding site. Proc Natl Acad Sci U S A (2004) 1.38
The unique insert at the end of the myosin VI motor is the sole determinant of directionality. Proc Natl Acad Sci U S A (2007) 1.30
Structural basis for ARF1-mediated recruitment of ARHGAP21 to Golgi membranes. EMBO J (2007) 1.24
Distinct roles of doublecortin modulating the microtubule cytoskeleton. EMBO J (2006) 1.16
Cadherin-23, myosin VIIa and harmonin, encoded by Usher syndrome type I genes, form a ternary complex and interact with membrane phospholipids. Hum Mol Genet (2010) 1.14
New insights into genotype-phenotype correlations for the doublecortin-related lissencephaly spectrum. Brain (2013) 1.14
Free Brick1 is a trimeric precursor in the assembly of a functional wave complex. PLoS One (2008) 1.09
Molecular basis for specific regulation of neuronal kinesin-3 motors by doublecortin family proteins. Mol Cell (2012) 1.08
The structural basis of Arf effector specificity: the crystal structure of ARF6 in a complex with JIP4. EMBO J (2009) 1.07
Biochemical and functional characterization of Rab27a mutations occurring in Griscelli syndrome patients. Blood (2002) 1.03
An overview and online registry of microvillus inclusion disease patients and their MYO5B mutations. Hum Mutat (2013) 0.99
The post-rigor structure of myosin VI and implications for the recovery stroke. EMBO J (2007) 0.98
Biochemical and structural characterization of the gem GTPase. J Biol Chem (2006) 0.93
MAPping out distribution routes for kinesin couriers. Biol Cell (2013) 0.90
Electrospray ionization mass spectrometry studies of noncovalent myosin VI complexes reveal a new specific calmodulin binding site. J Am Soc Mass Spectrom (2005) 0.89
Structural aspects of Rab6-effector complexes. Biochem Soc Trans (2009) 0.87
Role of insert-1 of myosin VI in modulating nucleotide affinity. J Biol Chem (2011) 0.87
Isolation and characterization of an aggresome determinant in the NF2 tumor suppressor. J Biol Chem (2002) 0.84
Drosophila melanogaster myosin-18 represents a highly divergent motor with actin tethering properties. J Biol Chem (2011) 0.84
A double-take on MAPs. Nat Struct Biol (2003) 0.78
Structural studies of the doublecortin family of MAPs. Methods Cell Biol (2013) 0.75
[A myosin that moves backwards]. Med Sci (Paris) (2006) 0.75