PubRank

Nicole M Thielens

Author PubWeight™ 49.34‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Structure and activation of the C1 complex of complement: unraveling the puzzle. Trends Immunol 2004 1.59
2 Structural insights into the Slit-Robo complex. Proc Natl Acad Sci U S A 2007 1.54
3 Structural insights into the innate immune recognition specificities of L- and H-ficolins. EMBO J 2007 1.53
4 Synergy between ficolin-2 and pentraxin 3 boosts innate immune recognition and complement deposition. J Biol Chem 2009 1.29
5 X-ray structure of the Ca2+-binding interaction domain of C1s. Insights into the assembly of the C1 complex of complement. J Biol Chem 2003 1.21
6 Carbohydrate recognition properties of human ficolins: glycan array screening reveals the sialic acid binding specificity of M-ficolin. J Biol Chem 2009 1.16
7 Human astrovirus coat protein binds C1q and MBL and inhibits the classical and lectin pathways of complement activation. Mol Immunol 2009 1.14
8 The crystal structure of the zymogen catalytic domain of complement protease C1r reveals that a disruptive mechanical stress is required to trigger activation of the C1 complex. EMBO J 2002 1.13
9 Identification of the C1q-binding Sites of Human C1r and C1s: a refined three-dimensional model of the C1 complex of complement. J Biol Chem 2009 1.13
10 Molecular organization of human Ficolin-2. Mol Immunol 2006 1.11
11 Residue Lys57 in the collagen-like region of human L-ficolin and its counterpart Lys47 in H-ficolin play a key role in the interaction with the mannan-binding lectin-associated serine proteases and the collectin receptor calreticulin. J Immunol 2009 1.11
12 Modified low density lipoproteins differentially bind and activate the C1 complex of complement. Mol Immunol 2006 1.08
13 Crystal structure of the CUB1-EGF-CUB2 domain of human MASP-1/3 and identification of its interaction sites with mannan-binding lectin and ficolins. J Biol Chem 2008 1.08
14 Structural basis for innate immune sensing by M-ficolin and its control by a pH-dependent conformational switch. J Biol Chem 2007 1.04
15 Studies on the interactions between C-reactive protein and complement proteins. Immunology 2007 1.01
16 Heteromeric complexes of native collectin kidney 1 and collectin liver 1 are found in the circulation with MASPs and activate the complement system. J Immunol 2013 1.01
17 The two major oligomeric forms of human mannan-binding lectin: chemical characterization, carbohydrate-binding properties, and interaction with MBL-associated serine proteases. J Immunol 2005 1.00
18 Identification of the site of human mannan-binding lectin involved in the interaction with its partner serine proteases: the essential role of Lys55. J Immunol 2007 0.99
19 Characterization of recombinant mannan-binding lectin-associated serine protease (MASP)-3 suggests an activation mechanism different from that of MASP-1 and MASP-2. J Immunol 2004 0.98
20 Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism. Structure 2002 0.98
21 M-ficolin interacts with the long pentraxin PTX3: a novel case of cross-talk between soluble pattern-recognition molecules. J Immunol 2011 0.96
22 Elucidation of the substrate specificity of the MASP-2 protease of the lectin complement pathway and identification of the enzyme as a major physiological target of the serpin, C1-inhibitor. Mol Immunol 2007 0.95
23 Expression of recombinant human complement C1q allows identification of the C1r/C1s-binding sites. Proc Natl Acad Sci U S A 2013 0.94
24 Cutting edge: C1q binds deoxyribose and heparan sulfate through neighboring sites of its recognition domain. J Immunol 2010 0.94
25 Assembly of C1 and the MBL- and ficolin-MASP complexes: structural insights. Immunobiology 2006 0.93
26 The X-ray structure of human mannan-binding lectin-associated protein 19 (MAp19) and its interaction site with mannan-binding lectin and L-ficolin. J Biol Chem 2004 0.93
27 Oxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner. J Biol Chem 2013 0.92
28 Structural insights into the recognition properties of human ficolins. J Innate Immun 2009 0.92
29 The human c1q globular domain: structure and recognition of non-immune self ligands. Front Immunol 2012 0.91
30 Structural biology of the C1 complex of complement unveils the mechanisms of its activation and proteolytic activity. Mol Immunol 2002 0.91
31 Complement protein C1q recognizes a conformationally modified form of the prion protein. Biochemistry 2005 0.91
32 Characterization of the interaction between L-ficolin/p35 and mannan-binding lectin-associated serine proteases-1 and -2. J Immunol 2002 0.89
33 Human and pneumococcal cell surface glyceraldehyde-3-phosphate dehydrogenase (GAPDH) proteins are both ligands of human C1q protein. J Biol Chem 2012 0.88
34 The lectin-like activity of human C1q and its implication in DNA and apoptotic cell recognition. FEBS Lett 2008 0.87
35 Structure and properties of the Ca(2+)-binding CUB domain, a widespread ligand-recognition unit involved in major biological functions. Biochem J 2011 0.87
36 Deciphering complement receptor type 1 interactions with recognition proteins of the lectin complement pathway. J Immunol 2013 0.87
37 Complement protein C1q forms a complex with cytotoxic prion protein oligomers. J Biol Chem 2010 0.86
38 A novel peptide inhibitor of classical and lectin complement activation including ABO incompatibility. Mol Immunol 2012 0.86
39 Functional characterization of complement proteases C1s/mannan-binding lectin-associated serine protease-2 (MASP-2) chimeras reveals the higher C4 recognition efficacy of the MASP-2 complement control protein modules. J Biol Chem 2005 0.85
40 Direct interaction between CD91 and C1q. FEBS J 2010 0.85
41 Characterization of the interaction between collectin 11 (CL-11, CL-K1) and nucleic acids. Mol Immunol 2013 0.82
42 M-ficolin and leukosialin (CD43): new partners in neutrophil adhesion. J Leukoc Biol 2011 0.81
43 The role of nanometer-scaled ligand patterns in polyvalent binding by large mannan-binding lectin oligomers. J Immunol 2012 0.81
44 CD91 interacts with mannan-binding lectin (MBL) through the MBL-associated serine protease-binding site. FEBS J 2010 0.80
45 Functional role of the linker between the complement control protein modules of complement protease C1s. J Immunol 2005 0.80
46 Studies on the mechanisms of allergen-induced activation of the classical and lectin pathways of complement. Mol Immunol 2003 0.79
47 Classical complement pathway components C1r and C1s: purification from human serum and in recombinant form and functional characterization. Methods Mol Biol 2014 0.77
48 The double life of M-ficolin: what functions when circulating in serum and tethered to leukocyte surfaces? J Leukoc Biol 2011 0.76
49 The serine protease domain of MASP-3: enzymatic properties and crystal structure in complex with ecotin. PLoS One 2013 0.76
50 Protective effect of surfactant protein d in pulmonary vaccinia virus infection: implication of A27 viral protein. Viruses 2013 0.76
51 Structure, function and molecular genetics of human and murine C1r. Immunobiology 2002 0.75
52 A recombinant chimeric epidermal growth factor-like module with high binding affinity for integrins. J Biol Chem 2003 0.75
53 MASP interactions with plasma-derived MBL. Mol Immunol 2012 0.75