Published in Biol Cell on June 01, 2004
A role for serotonin (5-HT) in hepatic stellate cell function and liver fibrosis. Am J Pathol (2006) 1.24
Serotonin as a modulator of glutamate- and GABA-mediated neurotransmission: implications in physiological functions and in pathology. Curr Neuropharmacol (2006) 1.08
c-Src tyrosine kinase, a critical component for 5-HT2A receptor-mediated contraction in rat aorta. J Physiol (2008) 1.02
Serotonin 5-HT2C receptor protein expression is enriched in synaptosomal and post-synaptic compartments of rat cortex. J Neurochem (2010) 0.98
Irving Page Lecture: 5-HT(2A) serotonin receptor biology: interacting proteins, kinases and paradoxical regulation. Neuropharmacology (2011) 0.97
Anxious interactions. Nat Neurosci (2010) 0.83
Systematic protein-protein interaction mapping for clinically relevant human GPCRs. Mol Syst Biol (2017) 0.75
Shank expression is sufficient to induce functional dendritic spine synapses in aspiny neurons. J Neurosci (2005) 2.96
Engineering GPCR signaling pathways with RASSLs. Nat Methods (2008) 2.29
Chromatin and sequence features that define the fine and gross structure of genomic methylation patterns. Genome Res (2010) 2.25
Angiogenesis is associated with blood-brain barrier permeability in temporal lobe epilepsy. Brain (2007) 1.83
Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome Med (2011) 1.78
GPCR interacting proteins (GIP). Pharmacol Ther (2004) 1.61
Plant insecticide L-canavanine repels Drosophila via the insect orphan GPCR DmX. PLoS Biol (2009) 1.60
Inflammatory reactions in human medial temporal lobe epilepsy with hippocampal sclerosis. Brain Res (2002) 1.53
A single mutation in the 5-HT4 receptor (5-HT4-R D100(3.32)A) generates a Gs-coupled receptor activated exclusively by synthetic ligands (RASSL). J Biol Chem (2002) 1.42
New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targeting. J Cell Sci (2004) 1.40
Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca2+-dependent K+ channels in cerebellar neurons. Proc Natl Acad Sci U S A (2007) 1.40
Neuronal 5-HT metabotropic receptors: fine-tuning of their structure, signaling, and roles in synaptic modulation. Cell Tissue Res (2006) 1.38
Signaling at G-protein-coupled serotonin receptors: recent advances and future research directions. Trends Pharmacol Sci (2008) 1.37
GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells. J Biol Chem (2009) 1.36
Synaptic multiprotein complexes associated with 5-HT(2C) receptors: a proteomic approach. EMBO J (2002) 1.35
GPCR-jacking: from a new route in RTK signalling to a new concept in GPCR activation. Trends Pharmacol Sci (2007) 1.33
Shaggy, the homolog of glycogen synthase kinase 3, controls neuromuscular junction growth in Drosophila. J Neurosci (2004) 1.32
The 'magic tail' of G protein-coupled receptors: an anchorage for functional protein networks. FEBS Lett (2003) 1.32
Conformational toggle switches implicated in basal constitutive and agonist-induced activated states of 5-hydroxytryptamine-4 receptors. Mol Pharmacol (2009) 1.29
GPCR interacting proteins (GIPs) in the nervous system: Roles in physiology and pathologies. Annu Rev Pharmacol Toxicol (2010) 1.27
The serotonin 5-HT2A and 5-HT2C receptors interact with specific sets of PDZ proteins. J Biol Chem (2004) 1.25
Co-assembly of two GluR6 kainate receptor splice variants within a functional protein complex. Neuron (2005) 1.24
G protein activation by serotonin type 4 receptor dimers: evidence that turning on two protomers is more efficient. J Biol Chem (2011) 1.21
Epileptiform activity induces vascular remodeling and zonula occludens 1 downregulation in organotypic hippocampal cultures: role of VEGF signaling pathways. J Neurosci (2011) 1.19
Proteomic analysis of astrocytic secretion in the mouse. Comparison with the cerebrospinal fluid proteome. J Biol Chem (2003) 1.18
Epac mediates PACAP-dependent long-term depression in the hippocampus. J Physiol (2008) 1.17
Homer-dependent cell surface expression of metabotropic glutamate receptor type 5 in neurons. Mol Cell Neurosci (2002) 1.15
Increased number of neural progenitors in human temporal lobe epilepsy. Neurobiol Dis (2005) 1.12
Direct interaction enables cross-talk between ionotropic and group I metabotropic glutamate receptors. J Biol Chem (2008) 1.11
The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C. J Biol Chem (2011) 1.11
Inverse agonist and neutral antagonist actions of antidepressants at recombinant and native 5-hydroxytryptamine2C receptors: differential modulation of cell surface expression and signal transduction. Mol Pharmacol (2007) 1.10
Attenuated response to stress and novelty and hypersensitivity to seizures in 5-HT4 receptor knock-out mice. J Neurosci (2004) 1.10
Physical interaction of calmodulin with the 5-hydroxytryptamine2C receptor C-terminus is essential for G protein-independent, arrestin-dependent receptor signaling. Mol Biol Cell (2008) 1.08
Subcellular imaging of dynamic protein interactions by bioluminescence resonance energy transfer. Biophys J (2007) 1.08
Anorexia induced by activation of serotonin 5-HT4 receptors is mediated by increases in CART in the nucleus accumbens. Proc Natl Acad Sci U S A (2007) 1.06
MethylomeDB: a database of DNA methylation profiles of the brain. Nucleic Acids Res (2011) 1.06
Genome-wide divergence of DNA methylation marks in cerebral and cerebellar cortices. PLoS One (2010) 1.03
Calpain product of WT-CRMP2 reduces the amount of surface NR2B NMDA receptor subunit. J Neurochem (2006) 1.03
PICK1 uncoupling from mGluR7a causes absence-like seizures. Nat Neurosci (2008) 1.03
Akt mediates the anti-apoptotic effect of NMDA but not that induced by potassium depolarization in cultured cerebellar granule cells. Eur J Neurosci (2002) 1.03
Stimulation of the ERK pathway by GTP-loaded Rap1 requires the concomitant activation of Ras, protein kinase C, and protein kinase A in neuronal cells. J Biol Chem (2002) 1.01
The Drosophila metabotropic glutamate receptor DmGluRA regulates activity-dependent synaptic facilitation and fine synaptic morphology. J Neurosci (2004) 1.00
Opposite effects of PSD-95 and MPP3 PDZ proteins on serotonin 5-hydroxytryptamine2C receptor desensitization and membrane stability. Mol Biol Cell (2006) 1.00
A model for the functioning of family 3 GPCRs. Trends Pharmacol Sci (2002) 0.99
Muscle dystroglycan organizes the postsynapse and regulates presynaptic neurotransmitter release at the Drosophila neuromuscular junction. PLoS One (2008) 0.99
G protein-coupled receptors: dominant players in cell-cell communication. Int Rev Cytol (2002) 0.99
Metabotropic glutamate receptor 2/3-dependent long-term depression in the nucleus accumbens is blocked in morphine withdrawn mice. Eur J Neurosci (2002) 0.99
The proteomic analysis of mouse choroid plexus secretome reveals a high protein secretion capacity of choroidal epithelial cells. Proteomics (2006) 0.97
Motoneurons secrete angiogenin to induce RNA cleavage in astroglia. J Neurosci (2012) 0.97
5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia. EMBO Mol Med (2012) 0.95
Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling. EMBO J (2009) 0.95
Enhanced detection of CNS cell secretome in plasma protein-depleted cerebrospinal fluid. J Proteome Res (2008) 0.95
Identification of new proteins in follicular fluid of mature human follicles. Electrophoresis (2002) 0.94
Adaptive changes in serotonin neurons of the raphe nuclei in 5-HT(4) receptor knock-out mouse. Eur J Neurosci (2006) 0.94
Homer1a-dependent crosstalk between NMDA and metabotropic glutamate receptors in mouse neurons. PLoS One (2010) 0.94
Uncoupling and endocytosis of 5-hydroxytryptamine 4 receptors. Distinct molecular events with different GRK2 requirements. J Biol Chem (2005) 0.92
Dynamic remodeling of scaffold interactions in dendritic spines controls synaptic excitability. J Cell Biol (2012) 0.92
Alzheimer culprits: cellular crossroads and interplay. Cell Signal (2012) 0.91
Collapsin response mediator protein 4a (CRMP4a) is upregulated in motoneurons of mutant SOD1 mice and can trigger motoneuron axonal degeneration and cell death. J Neurosci (2010) 0.91
MacMARCKS interacts with the metabotropic glutamate receptor type 7 and modulates G protein-mediated constitutive inhibition of calcium channels. J Neurochem (2006) 0.91
A 5-HT4 receptor transmembrane network implicated in the activity of inverse agonists but not agonists. J Biol Chem (2002) 0.90
PACAP type I receptor transactivation is essential for IGF-1 receptor signalling and antiapoptotic activity in neurons. EMBO J (2007) 0.90
β-Arrestin2 plays a key role in the modulation of the pancreatic beta cell mass in mice. Diabetologia (2013) 0.89
Characterization and localization of cocaine- and amphetamine-regulated transcript (CART) binding sites. Peptides (2005) 0.89
Shank3-Rich2 interaction regulates AMPA receptor recycling and synaptic long-term potentiation. J Neurosci (2013) 0.89
Divergent evolution in metabotropic glutamate receptors. A new receptor activated by an endogenous ligand different from glutamate in insects. J Biol Chem (2003) 0.89
Difference in mass analysis using labeled lysines (DIMAL-K): a new, efficient proteomic quantification method applied to the analysis of astrocytic secretomes. Mol Cell Proteomics (2005) 0.89
5-hydroxytryptamine 4 receptor activation of the extracellular signal-regulated kinase pathway depends on Src activation but not on G protein or beta-arrestin signaling. Mol Biol Cell (2007) 0.89
A proteomic approach based on peptide affinity chromatography, 2-dimensional electrophoresis and mass spectrometry to identify multiprotein complexes interacting with membrane-bound receptors. Biol Proced Online (2002) 0.89
Frontocortical 5-HT4 receptors exert positive feedback on serotonergic activity: viral transfections, subacute and chronic treatments with 5-HT4 agonists. Biol Psychiatry (2005) 0.88
beta-Arrestin 1 is required for PAC1 receptor-mediated potentiation of long-lasting ERK1/2 activation by glucose in pancreatic beta-cells. J Biol Chem (2008) 0.88
Constitutive activity of serotonin 2C receptors at G protein-independent signaling: modulation by RNA editing and antidepressants. Mol Pharmacol (2010) 0.88
Role of CpG context and content in evolutionary signatures of brain DNA methylation. Epigenetics (2011) 0.86
5-HT4 receptors constitutively promote the non-amyloidogenic pathway of APP cleavage and interact with ADAM10. ACS Chem Neurosci (2012) 0.86
Synergistic Regulation of Cytosolic Ca2+ Concentration by Adenosine and alpha1-Adrenergic Agonists in Mouse Striatal Astrocytes. Eur J Neurosci (1991) 0.86