PubRank

Joël Bockaert

Author PubWeight™ 84.33‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Shank expression is sufficient to induce functional dendritic spine synapses in aspiny neurons. J Neurosci 2005 2.96
2 Engineering GPCR signaling pathways with RASSLs. Nat Methods 2008 2.29
3 Angiogenesis is associated with blood-brain barrier permeability in temporal lobe epilepsy. Brain 2007 1.83
4 Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome Med 2011 1.78
5 Plant insecticide L-canavanine repels Drosophila via the insect orphan GPCR DmX. PLoS Biol 2009 1.60
6 Inflammatory reactions in human medial temporal lobe epilepsy with hippocampal sclerosis. Brain Res 2002 1.53
7 A single mutation in the 5-HT4 receptor (5-HT4-R D100(3.32)A) generates a Gs-coupled receptor activated exclusively by synthetic ligands (RASSL). J Biol Chem 2002 1.42
8 New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targeting. J Cell Sci 2004 1.40
9 Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca2+-dependent K+ channels in cerebellar neurons. Proc Natl Acad Sci U S A 2007 1.40
10 GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells. J Biol Chem 2009 1.36
11 Synaptic multiprotein complexes associated with 5-HT(2C) receptors: a proteomic approach. EMBO J 2002 1.35
12 GPCR-jacking: from a new route in RTK signalling to a new concept in GPCR activation. Trends Pharmacol Sci 2007 1.33
13 Shaggy, the homolog of glycogen synthase kinase 3, controls neuromuscular junction growth in Drosophila. J Neurosci 2004 1.32
14 Conformational toggle switches implicated in basal constitutive and agonist-induced activated states of 5-hydroxytryptamine-4 receptors. Mol Pharmacol 2009 1.29
15 The serotonin 5-HT2A and 5-HT2C receptors interact with specific sets of PDZ proteins. J Biol Chem 2004 1.25
16 G protein activation by serotonin type 4 receptor dimers: evidence that turning on two protomers is more efficient. J Biol Chem 2011 1.21
17 Epileptiform activity induces vascular remodeling and zonula occludens 1 downregulation in organotypic hippocampal cultures: role of VEGF signaling pathways. J Neurosci 2011 1.19
18 Proteomic analysis of astrocytic secretion in the mouse. Comparison with the cerebrospinal fluid proteome. J Biol Chem 2003 1.18
19 Epac mediates PACAP-dependent long-term depression in the hippocampus. J Physiol 2008 1.17
20 Homer-dependent cell surface expression of metabotropic glutamate receptor type 5 in neurons. Mol Cell Neurosci 2002 1.15
21 Increased number of neural progenitors in human temporal lobe epilepsy. Neurobiol Dis 2005 1.12
22 Direct interaction enables cross-talk between ionotropic and group I metabotropic glutamate receptors. J Biol Chem 2008 1.11
23 Attenuated response to stress and novelty and hypersensitivity to seizures in 5-HT4 receptor knock-out mice. J Neurosci 2004 1.10
24 Inverse agonist and neutral antagonist actions of antidepressants at recombinant and native 5-hydroxytryptamine2C receptors: differential modulation of cell surface expression and signal transduction. Mol Pharmacol 2007 1.10
25 Physical interaction of calmodulin with the 5-hydroxytryptamine2C receptor C-terminus is essential for G protein-independent, arrestin-dependent receptor signaling. Mol Biol Cell 2008 1.08
26 Subcellular imaging of dynamic protein interactions by bioluminescence resonance energy transfer. Biophys J 2007 1.08
27 Anorexia induced by activation of serotonin 5-HT4 receptors is mediated by increases in CART in the nucleus accumbens. Proc Natl Acad Sci U S A 2007 1.06
28 Akt mediates the anti-apoptotic effect of NMDA but not that induced by potassium depolarization in cultured cerebellar granule cells. Eur J Neurosci 2002 1.03
29 PICK1 uncoupling from mGluR7a causes absence-like seizures. Nat Neurosci 2008 1.03
30 Stimulation of the ERK pathway by GTP-loaded Rap1 requires the concomitant activation of Ras, protein kinase C, and protein kinase A in neuronal cells. J Biol Chem 2002 1.01
31 The Drosophila metabotropic glutamate receptor DmGluRA regulates activity-dependent synaptic facilitation and fine synaptic morphology. J Neurosci 2004 1.00
32 Opposite effects of PSD-95 and MPP3 PDZ proteins on serotonin 5-hydroxytryptamine2C receptor desensitization and membrane stability. Mol Biol Cell 2006 1.00
33 A model for the functioning of family 3 GPCRs. Trends Pharmacol Sci 2002 0.99
34 Metabotropic glutamate receptor 2/3-dependent long-term depression in the nucleus accumbens is blocked in morphine withdrawn mice. Eur J Neurosci 2002 0.99
35 Muscle dystroglycan organizes the postsynapse and regulates presynaptic neurotransmitter release at the Drosophila neuromuscular junction. PLoS One 2008 0.99
36 The proteomic analysis of mouse choroid plexus secretome reveals a high protein secretion capacity of choroidal epithelial cells. Proteomics 2006 0.97
37 5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia. EMBO Mol Med 2012 0.95
38 Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling. EMBO J 2009 0.95
39 Enhanced detection of CNS cell secretome in plasma protein-depleted cerebrospinal fluid. J Proteome Res 2008 0.95
40 Adaptive changes in serotonin neurons of the raphe nuclei in 5-HT(4) receptor knock-out mouse. Eur J Neurosci 2006 0.94
41 Homer1a-dependent crosstalk between NMDA and metabotropic glutamate receptors in mouse neurons. PLoS One 2010 0.94
42 Uncoupling and endocytosis of 5-hydroxytryptamine 4 receptors. Distinct molecular events with different GRK2 requirements. J Biol Chem 2005 0.92
43 Dynamic remodeling of scaffold interactions in dendritic spines controls synaptic excitability. J Cell Biol 2012 0.92
44 MacMARCKS interacts with the metabotropic glutamate receptor type 7 and modulates G protein-mediated constitutive inhibition of calcium channels. J Neurochem 2006 0.91
45 Alzheimer culprits: cellular crossroads and interplay. Cell Signal 2012 0.91
46 A 5-HT4 receptor transmembrane network implicated in the activity of inverse agonists but not agonists. J Biol Chem 2002 0.90
47 PACAP type I receptor transactivation is essential for IGF-1 receptor signalling and antiapoptotic activity in neurons. EMBO J 2007 0.90
48 β-Arrestin2 plays a key role in the modulation of the pancreatic beta cell mass in mice. Diabetologia 2013 0.89
49 Shank3-Rich2 interaction regulates AMPA receptor recycling and synaptic long-term potentiation. J Neurosci 2013 0.89
50 Divergent evolution in metabotropic glutamate receptors. A new receptor activated by an endogenous ligand different from glutamate in insects. J Biol Chem 2003 0.89
51 Characterization and localization of cocaine- and amphetamine-regulated transcript (CART) binding sites. Peptides 2005 0.89
52 Difference in mass analysis using labeled lysines (DIMAL-K): a new, efficient proteomic quantification method applied to the analysis of astrocytic secretomes. Mol Cell Proteomics 2005 0.89
53 5-hydroxytryptamine 4 receptor activation of the extracellular signal-regulated kinase pathway depends on Src activation but not on G protein or beta-arrestin signaling. Mol Biol Cell 2007 0.89
54 A proteomic approach based on peptide affinity chromatography, 2-dimensional electrophoresis and mass spectrometry to identify multiprotein complexes interacting with membrane-bound receptors. Biol Proced Online 2002 0.89
55 beta-Arrestin 1 is required for PAC1 receptor-mediated potentiation of long-lasting ERK1/2 activation by glucose in pancreatic beta-cells. J Biol Chem 2008 0.88
56 Frontocortical 5-HT4 receptors exert positive feedback on serotonergic activity: viral transfections, subacute and chronic treatments with 5-HT4 agonists. Biol Psychiatry 2005 0.88
57 Constitutive activity of serotonin 2C receptors at G protein-independent signaling: modulation by RNA editing and antidepressants. Mol Pharmacol 2010 0.88
58 5-HT4 receptors constitutively promote the non-amyloidogenic pathway of APP cleavage and interact with ADAM10. ACS Chem Neurosci 2012 0.86
59 Molecular and functional characterization of proteins interacting with the C-terminal domains of 5-HT2 receptors: emergence of 5-HT2 "receptosomes". Biol Cell 2004 0.85
60 Caffeic acid phenethyl ester (CAPE) prevents inflammatory stress in organotypic hippocampal slice cultures. Brain Res Mol Brain Res 2003 0.85
61 Quantitative assessment of transcriptome differences between brain territories. Genome Res 2003 0.83
62 Widespread brain distribution of the Drosophila metabotropic glutamate receptor. Neuroreport 2008 0.82
63 Transcription of the mouse PAC1 receptor gene: cell-specific expression and regulation by Zac1. Biochim Biophys Acta 2002 0.82
64 Proteomic detection of prostate-specific antigen using a serum fractionation procedure: potential implication for new low-abundance cancer biomarkers detection. Anal Biochem 2005 0.82
65 Dynamic reorganization of the astrocyte actin cytoskeleton elicited by cAMP and PACAP: a role for phosphatidylInositol 3-kinase inhibition. Eur J Neurosci 2005 0.82
66 3,4-N-methlenedioxymethamphetamine-induced hypophagia is maintained in 5-HT1B receptor knockout mice, but suppressed by the 5-HT2C receptor antagonist RS102221. Neuropsychopharmacology 2005 0.81
67 S32212, a novel serotonin type 2C receptor inverse agonist/α2-adrenoceptor antagonist and potential antidepressant: I. A mechanistic characterization. J Pharmacol Exp Ther 2011 0.81
68 Effects of oral monosodium (L)-glutamate on insulin secretion and glucose tolerance in healthy volunteers. Br J Clin Pharmacol 2002 0.81
69 Constitutive secretion of protease nexin-1 by glial cells and its regulation by G-protein-coupled receptors. J Neurosci 2005 0.80
70 Quantitative phosphoproteomics unravels biased phosphorylation of serotonin 2A receptor at Ser280 by hallucinogenic versus nonhallucinogenic agonists. Mol Cell Proteomics 2014 0.79
71 Calcineurin interacts with the serotonin transporter C-terminus to modulate its plasma membrane expression and serotonin uptake. J Neurosci 2013 0.79
72 The melatonergic agonist and clinically active antidepressant, agomelatine, is a neutral antagonist at 5-HT(2C) receptors. Int J Neuropsychopharmacol 2010 0.79
73 Implication of p53 and caspase-3 in kainic acid but not in N-methyl-D-aspartic acid-induced apoptosis in organotypic hippocampal mouse cultures. Neurosci Lett 2002 0.79
74 Inhibition of voltage-gated Ca2+ channels by antazoline. Neuroreport 2002 0.79
75 Effect of Glutamate and Ionomycin on the Release of Arachidonic Acid, Prostaglandins and HETEs from Cultured Neurons and Astrocytes. Eur J Neurosci 1991 0.79
76 [Feeding disorders in 5-HT4 receptor knockout mice]. J Soc Biol 2004 0.79
77 Gαo is required for L-canavanine detection in Drosophila. PLoS One 2013 0.78
78 Up-regulation of the PACAP type-1 receptor (PAC1) promoter by neurotrophins in rat PC12 cells and mouse cerebellar granule cells via the Ras/mitogen-activated protein kinase cascade. J Neurochem 2002 0.78
79 The Identification and Localization of the Guanine Nucleotide Binding Protein G0 in the Auditory System. Eur J Neurosci 1991 0.78
80 Hyperfunction of muscarinic receptor maintains long-term memory in 5-HT4 receptor knock-out mice. PLoS One 2010 0.78
81 Immature-like astrocytes are associated with dentate granule cell migration in human temporal lobe epilepsy. Neurosci Lett 2002 0.77
82 Quantitative proteomic analysis reveals protein expression changes in the murine neuronal secretome during apoptosis. J Proteomics 2012 0.77
83 Enhancement of reference memory in aged rats by specific activation of 5-HT(4) receptors using an olfactory associative discrimination task. Brain Res 2011 0.76
84 Pharmacological profile of engineered 5-HT₄ receptors and identification of 5-HT₄ receptor-biased ligands. Brain Res 2012 0.75
85 [When two molecules involved in the regulation of mood meet: mutual modulation of the serotonin transporter and neuronal NO-synthase]. Med Sci (Paris) 2007 0.75
86 [The mTOR pathway: a new target for treating cognitive deficits of schizophrenia?]. Med Sci (Paris) 2013 0.75
87 Techniques for studying inverse agonist activity of antidepressants at recombinant nonedited 5-HT(₂C-INI) receptor and native neuronal 5-HT(₂C) receptors. Methods Enzymol 2010 0.75