Published in Nat Med on July 11, 2004
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Staphylococcus aureus protein A activates TACE through EGFR-dependent signaling. EMBO J (2007) 1.32
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Microbial patterns signaling via Toll-like receptors 2 and 5 contribute to epithelial repair, growth and survival. PLoS One (2008) 1.22
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Staphylococcus aureus beta-toxin induces lung injury through syndecan-1. Am J Pathol (2009) 1.16
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Toxin-induced necroptosis is a major mechanism of Staphylococcus aureus lung damage. PLoS Pathog (2015) 1.11
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Immunostimulatory properties of the emerging pathogen Stenotrophomonas maltophilia. Infect Immun (2007) 1.11
Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome. J Leukoc Biol (2012) 1.11
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Non-spa-typeable clinical Staphylococcus aureus strains are naturally occurring protein A mutants. J Clin Microbiol (2009) 0.96
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The chaperone ClpX stimulates expression of Staphylococcus aureus protein A by Rot dependent and independent pathways. PLoS One (2010) 0.95
Concurrent proinflammatory and apoptotic activity of a Helicobacter pylori protein (HP986) points to its role in chronic persistence. PLoS One (2011) 0.95
Bacterial pathogens activate a common inflammatory pathway through IFNλ regulation of PDCD4. PLoS Pathog (2013) 0.94
Regulation of exoprotein gene expression by the Staphylococcus aureus cvfB gene. Infect Immun (2007) 0.94
Fibronectin-binding protein B variation in Staphylococcus aureus. BMC Microbiol (2010) 0.94
Host chemokines bind to Staphylococcus aureus and stimulate protein A release. J Biol Chem (2010) 0.93
Staphylococcus aureus elicits marked alterations in the airway proteome during early pneumonia. Infect Immun (2008) 0.93
The yjeQ gene is required for virulence of Staphylococcus aureus. Infect Immun (2006) 0.93
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Staphylococcus aureus protein A plays a critical role in mediating bone destruction and bone loss in osteomyelitis. PLoS One (2012) 0.92
Exploring Staphylococcus aureus pathways to disease for vaccine development. Semin Immunopathol (2011) 0.90
Shedding of tumor necrosis factor receptor 1 induced by protein A decreases tumor necrosis factor alpha availability and inflammation during systemic Staphylococcus aureus infection. Infect Immun (2013) 0.90
BDCA1-positive dendritic cells (DCs) represent a unique human myeloid DC subset that induces innate and adaptive immune responses to Staphylococcus aureus Infection. Infect Immun (2014) 0.89
A disintegrin and metalloproteinase 17 (ADAM17) and epidermal growth factor receptor (EGFR) signaling drive the epithelial response to Staphylococcus aureus toxic shock syndrome toxin-1 (TSST-1). J Biol Chem (2012) 0.89
Host airway proteins interact with Staphylococcus aureus during early pneumonia. Infect Immun (2008) 0.87
Soluble CD14 and CD83 from human neonatal antigen-presenting cells are inducible by commensal bacteria and suppress allergen-induced human neonatal Th2 differentiation. Infect Immun (2007) 0.87
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Staphylococcus aureus protein A induced inflammatory response in human corneal epithelial cells. Biochem Biophys Res Commun (2007) 0.84
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The statistical conformation of a highly flexible protein: small-angle X-ray scattering of S. aureus protein A. Structure (2014) 0.82
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Innate Immune Signaling Activated by MDR Bacteria in the Airway. Physiol Rev (2016) 0.81
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Mapping the transcription start points of the Staphylococcus aureus eap, emp, and vwb promoters reveals a conserved octanucleotide sequence that is essential for expression of these genes. J Bacteriol (2007) 0.81
Genome-wide analysis of the regulatory function mediated by the small regulatory psm-mec RNA of methicillin-resistant Staphylococcus aureus. Int J Med Microbiol (2014) 0.81
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Host defense proteins derived from human saliva bind to Staphylococcus aureus. Infect Immun (2013) 0.80
Identification of staphylococcal protein A in infected atopic dermatitis lesions. J Invest Dermatol (2010) 0.80
Role of Staphylococcus aureus Virulence Factors in Inducing Inflammation and Vascular Permeability in a Mouse Model of Bacterial Endophthalmitis. PLoS One (2015) 0.80
Suppression of conformational heterogeneity at a protein-protein interface. Proc Natl Acad Sci U S A (2015) 0.79
The Role of Staphylococcus aureus Virulence Factors in Skin Infection and Their Potential as Vaccine Antigens. Pathogens (2016) 0.79
Diverse modulation of spa transcription by cell wall active antibiotics in Staphylococcus aureus. BMC Res Notes (2012) 0.79
The Sbi Protein Contributes to Staphylococcus aureus Inflammatory Response during Systemic Infection. PLoS One (2015) 0.79
EV71-infected CD14(+) cells modulate the immune activity of T lymphocytes in rhesus monkeys. Emerg Microbes Infect (2013) 0.79
Staphylococcal protein A inflames the lungs. Nat Med (2004) 0.78
Protein A is released into the Staphylococcus aureus culture supernatant with an unprocessed sorting signal. Infect Immun (2015) 0.77
Secretion of IL-16 through TNFR1 and calpain-caspase signaling contributes to MRSA pneumonia. Mucosal Immunol (2014) 0.77
Interaction of the GraRS two-component system with the VraFG ABC transporter to support vancomycin-intermediate resistance in Staphylococcus aureus. Antimicrob Agents Chemother (2007) 2.14
Pseudomonas aeruginosa flagella activate airway epithelial cells through asialoGM1 and toll-like receptor 2 as well as toll-like receptor 5. Am J Respir Cell Mol Biol (2003) 2.09
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TLR2-induced calpain cleavage of epithelial junctional proteins facilitates leukocyte transmigration. Cell Host Microbe (2009) 1.87
Staphylococcus aureus activates type I IFN signaling in mice and humans through the Xr repeated sequences of protein A. J Clin Invest (2009) 1.77
TLR2 is mobilized into an apical lipid raft receptor complex to signal infection in airway epithelial cells. J Clin Invest (2004) 1.70
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Staphylococcus aureus activation of caspase 1/calpain signaling mediates invasion through human keratinocytes. J Infect Dis (2012) 1.66
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Confinement-induced quorum sensing of individual Staphylococcus aureus bacteria. Nat Chem Biol (2009) 1.61
Bacterial neuraminidase facilitates mucosal infection by participating in biofilm production. J Clin Invest (2006) 1.54
PP1/PP2A phosphatases are required for the second step of Pre-mRNA splicing and target specific snRNP proteins. Mol Cell (2006) 1.51
Regulation of Set9-mediated H4K20 methylation by a PWWP domain protein. Mol Cell (2009) 1.45
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The NanA neuraminidase of Streptococcus pneumoniae is involved in biofilm formation. Infect Immun (2009) 1.36
Streptococcus pneumoniae DNA initiates type I interferon signaling in the respiratory tract. MBio (2011) 1.34
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Staphylococcus aureus induces type I IFN signaling in dendritic cells via TLR9. J Immunol (2012) 1.16
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Participation of CD11c(+) leukocytes in methicillin-resistant Staphylococcus aureus clearance from the lung. Infect Immun (2011) 1.14
Repression of hla by rot is dependent on sae in Staphylococcus aureus. Infect Immun (2008) 1.14
Immunopathogenesis of Staphylococcus aureus pulmonary infection. Semin Immunopathol (2011) 1.12
Staphylococcus aureus protein A mediates invasion across airway epithelial cells through activation of RhoA GTPase signaling and proteolytic activity. J Biol Chem (2011) 1.11
Immunostimulatory properties of the emerging pathogen Stenotrophomonas maltophilia. Infect Immun (2007) 1.11
The staphylococcal respiratory response regulator SrrAB induces ica gene transcription and polysaccharide intercellular adhesin expression, protecting Staphylococcus aureus from neutrophil killing under anaerobic growth conditions. Mol Microbiol (2007) 1.10
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